Publications

• Identification of leukemia-enriched signature through the development of a comprehensive pediatric single-cell atlas.
  Nat Commun Volume: 16 Page(s): 4114
  05/02/2025 Authors: Mumme HL; Huang C; Ohlstrom D; Bakhtiari M; Raikar SS; DeRyckere D; Qayed M; Castellino SM; Wechsler DS; Porter CC
• Azacitidine as epigenetic priming for chemotherapy is safe and well-tolerated in infants with newly diagnosed KMT2A-rearranged acute lymphoblastic leukemia: Children's Oncology Group trial AALL15P1.
  Haematologica Volume: 109 Page(s): 3918 - 3927
  12/01/2024 Authors: Guest EM; Kairalla JA; Devidas M; Hibbitts E; Carroll AJ; Heerema NA; Kubaney HR; August MA; Ramesh S; Yoo B
• Prototypical innate immune mechanism hijacked by leukemia-initiating mutant stem cells for selective advantage and immune evasion in Ptpn11-associated juvenile myelomonocytic leukemia.
  Res Sq
  08/02/2024 Authors: Zheng H; Zhao P; Tan Z; Yu W-M; Werner J; Stieglitz E; Porter C; Chandrakasan S; Wechsler D; Mendez-Ferrer S
• Health Supervision for Children and Adolescents With Sickle Cell Disease: Clinical Report.
  Pediatrics Volume: 154
  08/01/2024 Authors: Yates AM; Aygun B; Nuss R; Rogers ZR; Section on Hematology/Oncology; AMERICAN SOCIETY OF PEDIATRIC HEMATOLOGY/ONCOLOGY
• Novel-and Not So Novel-Inhibitors of the Multifunctional CRM1 Protein.
  Oncol Rev Volume: 18 Page(s): 1427497
  01/01/2024 Authors: Aumann WK; Kazi R; Harrington AM; Wechsler DS
• Single-cell RNA sequencing distinctly characterizes the wide heterogeneity in pediatric mixed phenotype acute leukemia.
  Genome Med Volume: 15 Page(s): 83
  10/16/2023 Authors: Mumme HL; Raikar SS; Bhasin SS; Thomas BE; Lawrence T; Weinzierl EP; Pang Y; DeRyckere D; Gawad C; Wechsler DS
• Single-cell analysis reveals altered tumor microenvironments of relapse- and remission-associated pediatric acute myeloid leukemia.
  Nat Commun Volume: 14 Page(s): 6209
  10/05/2023 Authors: Mumme H; Thomas BE; Bhasin SS; Krishnan U; Dwivedi B; Perumalla P; Sarkar D; Ulukaya GB; Sabnis HS; Park SI
• BEYOND SOLID TUMORS: A PREVIOUSLY UNRECOGNIZED ROLE FOR SIX1 IN PEDIATRIC ACUTE LEUKEMIAS
  Volume: 70 Page(s): S45 - S46
  06/01/2023 Authors: Aumann W; Chen D; Lavau C; Reese T; Ford H; Wechsler D
• PEGASPARGASE LEVELS IN INFANTS WITH ACUTE LYMPHOBLASTIC LEUKEMIA: A REPORT FROM THE CHILDREN'S ONCOLOGY GROUP TRIAL AALL15P1
  Volume: 69
  11/01/2022 Authors: Faulk K; Kairalla J; Devidas M; Hibbitts E; Carroll A; Heerema N; Kubaney H; August A; Pauly M; Wechsler D
• Evaluation for Bleeding Disorders in Suspected Child Abuse.
  Pediatrics Volume: 150
  10/01/2022 Authors: Anderst J; Carpenter SL; Abshire TC; Killough E; AAP SECTION ON HEMATOLOGY/ONCOLOGY, THE AMERICAN SOCIETY OF PEDIATRIC HEMATOLOGY/ONCOLOGY, THE AAP COUNCIL ON CHILD ABUSE AND NEGLECT; Consultants; Mendonca EA; Downs SM; Section on Hematology/Oncology executive committee, 20202021; Wetmore C
• A NOVEL SIX1/EYA2 INHIBITOR IMPAIRS CALM-AF10 LEUKEMIA CELL PROLIFERATION
  Volume: 69
  06/01/2022 Authors: Aumann W; Lavau C; Chen D; Conway A; Ford H; Wechsler D
• ESTABLISHING THE CALM-AF10 INTERACTOME: POTENTIAL LEUKEMOGENIC ROLES FOR EPS15,DVL2, AND CTTN
  Volume: 69
  06/01/2022 Authors: Kazi R; Aumann W; Bagchi P; Wechsler D
• Comprehensive Genomic Profiling of High-Risk Pediatric Cancer Patients Has a Measurable Impact on Clinical Care.
  JCO Precis Oncol Volume: 6 Page(s): e2100451
  04/01/2022 Authors: Summers RJ; Castellino SM; Porter CC; MacDonald TJ; Basu GD; Szelinger S; Bhasin MK; Cash T; Carter AB; Castellino RC
• Multicenter Analysis of Genomically Targeted Single Patient Use Requests for Pediatric Neoplasms.
  J Clin Oncol Volume: 39 Page(s): 3822 - 3828
  12/01/2021 Authors: Sabnis HS; Shulman DS; Mizukawa B; Bouvier N; Zehir A; Fangusaro J; Fabrizio VA; Whitlow C; Winchester M; Agresta L
• Caught in the In-Between: Challenges in Treating Adolescents and Young Adults With Cancer.
  JCO Oncol Pract Volume: 17 Page(s): 299 - 301
  06/01/2021 Authors: Janardan SK; Wechsler DS
• CHARACTERIZING PROTEINS THAT MEDIATE CALM-AF10 LEUKEMOGENESIS
  Volume: 68 Page(s): S48 - S49
  06/01/2021 Authors: Kazi R; Aumann W; Bagchi P; Tope D; Wechsler D
• THE SIX1 HOMEOBOX PROTEIN IS A NOVEL THERAPEUTIC TARGET IN CALM-AF10 LEUKEMOGENESIS
  Volume: 68 Page(s): S49 - S50
  06/01/2021 Authors: Aumann W; Lavau C; Chen D; Tope D; Conway A; Zhou H; Ford H; Wechsler D
• Neonatal Malignant Tumors.
  Clin Perinatol Volume: 48 Page(s): xix - xx
  03/01/2021 Authors: Wechsler DS
• Fusion of the CRM1 nuclear export receptor to AF10 causes leukemia and transcriptional activation of HOXA genes.
  Leukemia Volume: 35 Page(s): 876 - 880
  03/01/2021 Authors: Aumann WK; Heath JL; Conway AE; Sze S-GK; Gupta VK; Kazi RR; Tope DR; Wechsler DS; Lavau CP
• Covid-19 will not "magically disappear": Why access to widespread testing is paramount.
  Am J Hematol Volume: 96 Page(s): 174 - 178
  02/01/2021 Authors: George PE; Stokes CL; Bassit LC; Chahroudi A; Figueroa J; Griffiths MA; Heilman S; Ku DN; Nehl EJ; Leong T
• Retrospective Diagnosis of Ataxia-Telangiectasia in an Adolescent Patient With a Remote History of T-Cell Leukemia.
  J Pediatr Hematol Oncol Volume: 43 Page(s): e138 - e140
  01/01/2021 Authors: Sze S-GK; Lederman HM; Crawford TO; Wangler MF; Lewis AM; Kastan MB; Dibra HK; Taylor AMR; Wechsler DS
• Characterizing Proteins That Mediate CALM-AF10 Leukemogenesis
  Volume: 136
  11/05/2020 Authors: Kazi R; Aumann WK; Bagchi P; Wechsler DS
• Single Cell Transcriptomics Revealed AML and Non-AML Cell Clusters Relevant to Relapse and Remission in Pediatric AML
  Volume: 136
  11/05/2020 Authors: Thomas BE; Perumalla P; Bhasin SS; Sarkar D; Dwivedi B; Park SI; DeRyckere D; Henry CJ; Raikar SS; Porter CC
• The SIX1 homeobox Gene Is a Novel Therapeutic Target in CALM-AF10 Leukemogenesis
  Volume: 136
  11/05/2020 Authors: Aumann WK; Lavau CP; Harrington A; Tope D; Conway AE; Zhou H; Ford H; Wechsler DS
• Very late recurrence of B-cell acute lymphoblastic leukemia masquerading as a pituitary tumor.
  Pediatr Hematol Oncol Volume: 37 Page(s): 438 - 444
  08/01/2020 Authors: Fridlyand DM; Keller FG; Sabnis HS; Patterson BC; Gadde JA; Peragallo JH; Biousse V; Wechsler DS
• Targeted therapies for children and young adults with cancer: Single-patient use (SPU) experience at three large pediatric cancer programs
  Volume: 80 Page(s): 69 - 70
  07/01/2020 Authors: Sabnis H; Mizukawa B; Glade-Bender J; Fangusaro J; Roberts S; Whitlow C; Winchester M; O'Brien M; Agresta L; Turpin B
• THE SIX1 HOMEOBOX GENE IS A NOVEL THERAPEUTIC TARGET IN CALM-AF10 LEUKEMOGENESIS
  Volume: 67 Page(s): S172 - S173
  06/01/2020 Authors: Aumann W; Lavau C; Tope D; Conway A; Patnaik S; Marugan J; Zhou H; Zhao R; Ford H; Wechsler D
• A ROLE FOR THE NUP214 NUCLEAR PORE PROTEIN IN LEUKEMOGENESIS
  Volume: 67 Page(s): S171 - S172
  06/01/2020 Authors: Harrington A; Aumann W; Tope D; Wechsler D
• IDENTIFICATION OF A POTENTIAL ROLE FOR EPS15 IN CALM-AF10 LEUKEMOGENESIS
  Volume: 67 Page(s): S167 - S168
  06/01/2020 Authors: Kazi R; Aumann W; Tope R; Wechsler D
• NEXT-GENERATION SEQUENCING REVEALS INCREASED PREVALENCE OF PICALM-MLLT10 FUSIONS IN T-ALL AND T-LLY
  Volume: 67 Page(s): S167 - S167
  06/01/2020 Authors: Summers R; Aumann W; Pauly M; Goldsmith K; Porter C; Worsley R; Graham D; Castellino S; Wechsler D
• Leukoerythroblastosis as an Unusual Presentation of Parvovirus B19 Infection in a Sickle Cell Patient.
  Case Rep Pediatr Volume: 2020 Page(s): 8841607
  01/01/2020 Authors: Patel PA; Weinzierl EP; Wechsler DS
• The SQSTM1-NUP214 fusion protein interacts with Crm1, activates Hoxa and Meis1 genes, and drives leukemogenesis in mice.
  PLoS One Volume: 15 Page(s): e0232036
  01/01/2020 Authors: Lavau CP; Aumann WK; Sze S-GK; Gupta V; Ripple K; Port SA; Kehlenbach RH; Wechsler DS
• The SQSTM1-NUP214 Fusion Protein Cooperates with Crm1 to Activate Hoxa Genes and Drives Leukemogenesis in Mice
  Volume: 134
  11/13/2019 Authors: Aumann WK; Sze S-GK; Gupta V; Ripple K; Port S; Kehlenbach R; Wechsler DS; Lavau CP
• SIX1 Is a Novel Effector Gene in CALM-AF10 Leukemia
  Volume: 134
  11/13/2019 Authors: Aumann WK; Lavau CP; Harrington A; Conway AE; Wechsler DS
• IDENTIFYING NOVEL CRM1-INTERACTING PROTEINS IN CALM-AF10 LEUKEMOGENESIS BY PROXIMITY BASED LABELING
  Volume: 66
  06/01/2019 Authors: Kazi R; Aumann W; Tope D; Wechsler D
• THE ROLE OF NUP214 IN MEDIATING THE INTERACTION BETWEEN CRM1 AND THE HOXA GENE LOCUS
  Volume: 66
  06/01/2019 Authors: Harrington A; Aumann W; Wechsler D; Tope D
• A ROLE FOR THE SIX1 HOMEOBOX GENE IN CALM-AF10 LEUKEMOGENESIS
  Volume: 66
  06/01/2019 Authors: Aumann W; Lavau C; Harrington A; Conway A; Wechsler D
• Favorable response to nivolumab in a young adult patient with metastatic histiocytic sarcoma.
  Pediatr Blood Cancer Volume: 66 Page(s): e27491
  01/01/2019 Authors: Bose S; Robles J; McCall CM; Lagoo AS; Wechsler DS; Schooler GR; Van Mater D
• FOXO3a-dependent up-regulation of Mxi1-0 promotes hypoxia-induced apoptosis in endothelial cells.
  Cell Signal Volume: 51 Page(s): 233 - 242
  11/01/2018 Authors: Hu Z; Wang F; Wu Z; Gu H; Dong N; Jiang X; Xu J; Wu Z; Wechsler DS; Zheng D
• Wilms Tumor After Orthotopic Liver Transplant in a Patient With Alagille Syndrome.
  Urology Volume: 121 Page(s): 171 - 174
  11/01/2018 Authors: Carlos EC; Ajay D; Muniz-Alers S; Wechsler DS; Sushama DV; Rice HE; Madden J; Routh JC
• Isolated Central Nervous System Chloroma as a Presenting Sign of Relapsed Pediatric Acute Lymphoblastic Leukemia.
  J Pediatr Hematol Oncol Volume: 40 Page(s): e442 - e445
  10/01/2018 Authors: Heath JL; Aumann WK; Maxfield CM; Wechsler DS
• Pediatric Cancer in Northern Tanzania: Evaluation of Diagnosis, Treatment, and Outcomes.
  J Glob Oncol Volume: 4 Page(s): 1 - 10
  09/01/2018 Authors: Schroeder K; Saxton A; McDade J; Chao C; Masalu N; Chao C; Wechsler DS; Likonda B; Chao N
• THE SIX1 HOMEOBOX GENE IS A NOVEL CRM1-DEPENDENT TARGET IN CALM-AF10 LEUKEMIAS
  Volume: 65
  06/01/2018 Authors: Aumann W; Conway A; Lavau C; Wechsler D
• Looking beyond the exome: a phenotype-first approach to molecular diagnostic resolution in rare and undiagnosed diseases.
  Genet Med Volume: 20 Page(s): 464 - 469
  04/01/2018 Authors: Pena LDM; Jiang Y-H; Schoch K; Spillmann RC; Walley N; Stong N; Rapisardo Horn S; Sullivan JA; McConkie-Rosell A; Kansagra S
• Adolescent and Young Adult Oncology, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology.
  J Natl Compr Canc Netw Volume: 16 Page(s): 66 - 97
  01/01/2018 Authors: Coccia PF; Pappo AS; Beaupin L; Borges VF; Borinstein SC; Chugh R; Dinner S; Folbrecht J; Frazier AL; Goldsby R
• A Role for the CRM1 Nuclear Export Receptor in HOXA Gene Deregulation and CALM-AF10Leukemogenesis
  Volume: 130
  12/07/2017 Authors: Aumann WK; Heath JL; Sze S-GK; Conway AE; Lavau CP; Wechsler DS
• MXI1 and MXI0 Differentially Affect N-MYC Expression in Neuroblastoma
  Volume: 64 Page(s): S46 - S46
  06/01/2017 Authors: Armstrong M; Murray E; Tope DR; Ellis DC; Bartram J; Wechsler D
• The Role of Nucleoporins in CALM-AF10 and CRM1-AF10 Leukemogenesis
  Volume: 64 Page(s): S39 - S39
  05/01/2014 Authors: Sze S-G; Port S; Kehlenbach R; Lavau C; Wechsler D
• The Six1 Homeobox Gene is a Novel Transcriptional Target of the Leukemogenic CALM-AF10 Protein
  Volume: 64 Page(s): S39 - S39
  05/01/2014 Authors: Aumann W; Reddy S; Lavau C; Wechsler D
• Insights into the Molecular Basis of CRM1-AF10 Leukemogenesis
  Volume: 64 Page(s): S38 - S38
  06/01/2017 Authors: Aumann W; Heath J; Conway A; Sze S-G; Gupta V; Lavau C; Wechsler D
• Transplanting One Problem for Another.
  Pediatrics Volume: 139
  05/01/2017 Authors: Borst AJ; Wechsler DS
• A positive feedback loop between ROS and Mxi1-0 promotes hypoxia-induced VEGF expression in human hepatocellular carcinoma cells.
  Cell Signal Volume: 31 Page(s): 79 - 86
  02/01/2017 Authors: Hu Z; Dong N; Lu D; Jiang X; Xu J; Wu Z; Zheng D; Wechsler DS
• The Role of MXI1 in Neuroblastoma Pathogenesis and Chemosensitivity
  Volume: 63 Page(s): S192 - S192
  11/01/2016 Authors: Bartram J; Ellis DC; Kirchner S; Wechsler D; Armstrong M
• MXI1 AND MXI0 HAVE DIFFERENTIAL EFFECTS ON NEUROBLASTOMA PATHOGENESIS AND CHEMOSENSITIVITY
  Volume: 63 Page(s): S58 - S58
  06/01/2016 Authors: Bartram J; Ellis DC; Kirchner S; Elssner I; Wechsler D; Armstrong M
• MXI1 AND MXI0, PUTATIVE N-MYC ANTAGONISTS IN NEUROBLASTOMA, DISPLAY DISTINCT SUBCELLULAR LOCALIZATION PATTERNS
  Volume: 63 Page(s): S61 - S62
  06/01/2016 Authors: Kirchner S; Bartram J; Wechsler D; Armstrong M
• The 2016 ASPHO Distinguished Career Award Goes to David G. Poplack, MD.
  Pediatr Blood Cancer Volume: 63 Suppl 1 Page(s): S5 - S6
  06/01/2016 Authors: Blaney SM; Adamson PC; Wechsler DS
• THE ROLE OF CRM1 DIMERIZATION IN CRM1-AF10 LEUKEMOGENESIS
  Volume: 63 Page(s): S11 - S11
  06/01/2016 Authors: Aumann W; Kim SG; Lavau C; Wechsler D
• THE ROLE OF NUP98 IN CALM-AF10 AND CRM1-AF10 LEUKEMOGENESIS
  Volume: 63 Page(s): S24 - S24
  06/01/2016 Authors: Kim SG; Aumann W; Lavau C; Wechsler D
• DISCOVERY OF NOVEL EFFECTOR GENES REGULATED BY CALM-AF10 IN PEDIATRIC LEUKEMIAS
  Volume: 63 Page(s): S22 - S22
  06/01/2016 Authors: Aumann W; Lavau C; Wechsler D
• The role of Exon 0 in mediating Mxi0 activity in neuroblastoma
  Volume: 76
  03/01/2016 Authors: Kirchner SJ; Bartram JT; Ellis DC; Wechsler DS; Armstrong MB
• MXI1 AND MXI0 HAVE DIFFERENTIAL IMPACT ON N-MYC FUNCTION IN NEUROBLASTOMA GROWTH AND CHEMOSENSITIVITY
  Volume: 62 Page(s): S224 - S224
  11/01/2015 Authors: Ellis DC; Kirchner S; Bartram J; Wechsler D; Armstrong M
• THE CRM1 NUCLEAR EXPORT RECEPTOR IS CRITICAL FOR THE EXPRESSION OF HOXA GENES AND CAN SUBSTITUTE FOR CALM IN CALM-AF10 LEUKEMOGENESIS
  Volume: 62 Page(s): S156 - S156
  11/01/2015 Authors: Wechsler D; Heath J; Aumann W; Lavau C
• PEDIATRIC ONCOLOGY IN THE LAKE REGION OF TANZANIA: EVALUATION OF CLINICAL DIAGNOSIS, TREATMENT AND OUTCOMES
  Volume: 62 Page(s): S296 - S296
  11/01/2015 Authors: Schroeder K; Chao C; Masalu N; Mafwimbo S; Mafwimbo J; Wechsler D; Chao N; Likonda B
• Persistent and Prolonged Parvovirus B19 Viremia in a Pediatric Patient With Acute Lymphoblastic Leukemia.
  J Pediatric Infect Dis Soc Volume: 4 Page(s): e38 - e40
  09/01/2015 Authors: Fritch Lilla SA; Burgett SE; McGann KA; Wechsler DS
• DIFFERENTIAL EFFECTS OF MXI1 AND MXI0 ON N-MYC-DEPENDENT NEUROBLASTOMA PATHOGENESIS AND CHEMOSENSITIVITY
  Volume: 62 Page(s): 98 - 98
  06/01/2015 Authors: Ellis DC; Kirchner S; Bartram J; Wechsler D; Armstrong M
• THE CRM1 NUCLEAR EXPORT RECEPTOR ACTIVATES HOXA GENE EXPRESSION IN SEVERAL LEUKEMIA MODELS
  Volume: 62 Page(s): 24 - 24
  06/01/2015 Authors: Heath J; Aumann W; Conway A; Lavau C; Wechsler D
• A critical role for CRM1 in regulating HOXA gene transcription in CALM-AF10 leukemias.
  Leukemia Volume: 29 Page(s): 423 - 432
  02/01/2015 Authors: Conway AE; Haldeman JM; Wechsler DS; Lavau CP
• Mxi1 and mxi1-0 antagonize N-myc function and independently mediate apoptosis in neuroblastoma.
  Transl Oncol Volume: 8 Page(s): 65 - 74
  02/01/2015 Authors: Erichsen DA; Armstrong MB; Wechsler DS
• Modulation of PICALM Levels Perturbs Cellular Cholesterol Homeostasis.
  PLoS One Volume: 10 Page(s): e0129776
  01/01/2015 Authors: Mercer JL; Argus JP; Crabtree DM; Keenan MM; Wilks MQ; Chi J-TA; Bensinger SJ; Lavau CP; Wechsler DS
• The CRM1 Nuclear Export Receptor Activates HOXA Gene Expression in Leukemogenesis
  Volume: 124
  03/01/2011 Authors: Lavau CP; Heath JL; Lee WH; Conway AE; Wechsler DS
• Effects of iron depletion on CALM-AF10 leukemias.
  Exp Hematol Volume: 42 Page(s): 1022 - 1030.e1
  12/01/2014 Authors: Heath JL; Weiss JM; Lavau CP; Wechsler DS
• Successful treatment of pediatric histiocytic sarcoma using abbreviated high-risk leukemia chemotherapy.
  Pediatr Blood Cancer Volume: 61 Page(s): 1874 - 1876
  10/01/2014 Authors: Heath JL; Burgett SE; Gaca AM; Jaffe R; Wechsler DS
• PICALM modulates autophagy activity and tau accumulation.
  Nat Commun Volume: 5 Page(s): 4998
  09/22/2014 Authors: Moreau K; Fleming A; Imarisio S; Lopez Ramirez A; Mercer JL; Jimenez-Sanchez M; Bento CF; Puri C; Zavodszky E; Siddiqi F
• TARGETING OF CALM-AF10 LEUKEMIAS BY IRON DEPRIVATION
  Volume: 61 Page(s): S49 - S49
  05/01/2014 Authors: Heath J; Lavau C; Weiss J; Wechsler D
• CRITICAL CONTRIBUTIONS OF CRM1 TO CALM-AF10 LEUKEMOGENESIS
  Volume: 61 Page(s): S48 - S49
  05/01/2014 Authors: Heath J; Conway A; Lavau C; Wechsler D
• TARGETING CALM-AF10 LEUKEMIA CELLS WITH NUCLEAR EXPORT INHIBITORS
  Volume: 61 Page(s): S24 - S24
  05/01/2014 Authors: Lilla SF; Conway A; Lavau C; Wechsler D
• Adolescent and young adult oncology, version 2.2014.
  J Natl Compr Canc Netw Volume: 12 Page(s): 21 - 32
  01/01/2014 Authors: Coccia PF; Pappo AS; Altman J; Bhatia S; Borinstein SC; Flynn J; Frazier AL; George S; Goldsby R; Hayashi R
• N-Myc differentially regulates expression of MXI1 isoforms in neuroblastoma.
  Neoplasia Volume: 15 Page(s): 1363 - 1370
  12/01/2013 Authors: Armstrong MB; Mody RJ; Ellis DC; Hill AB; Erichsen DA; Wechsler DS
• High motility group overexpression accelerates T-cell leukemogenesis.
  Leuk Lymphoma Volume: 54 Page(s): 1577 - 1578
  08/01/2013 Authors: Heath JL; Wechsler DS
• Iron deprivation in cancer--potential therapeutic implications.
  Nutrients Volume: 5 Page(s): 2836 - 2859
  07/24/2013 Authors: Heath JL; Weiss JM; Lavau CP; Wechsler DS
• A CALM-derived nuclear export signal is essential for CALM-AF10-mediated leukemogenesis.
  Blood Volume: 121 Page(s): 4758 - 4768
  06/06/2013 Authors: Conway AE; Scotland PB; Lavau CP; Wechsler DS
• CALM-AF10 LEUKEMIA CELL PROLIFERATION IS IMPAIRED BY IRON DEPRIVATION IN VITRO AND IN VIVO
  Volume: 60 Page(s): S40 - S40
  06/01/2013 Authors: Heath J; Lavau C; Weiss J; Scotland P; Wechsler D
• THE ROLES OF MXI1 AND MXI0 IN N-MYC-MEDIATED NEUROBLASTOMA TUMOR PATHOGENESIS
  Volume: 60 Page(s): S65 - S65
  06/01/2013 Authors: Armstrong M; Ellis DC; Wechsler D
• NUCLEAR EXPORT INHIBITORS REDUCE PROLIFERATION OF CALM-AF10 LEUKEMIA CELLS
  Volume: 60 Page(s): S41 - S42
  06/01/2013 Authors: Lilla SF; Conway A; Scotland P; Lavau C; Wechsler D
• Iron Deprivation Impairs Proliferation of CALM-AF10 leukemia Cells in Vitro and in Vivo
  Volume: 120
  11/16/2012 Authors: Heath JL; Weiss J; Scotland PB; Lavau CP; Wechsler DS
• Adolescent and young adult oncology. Clinical practice guidelines in oncology.
  J Natl Compr Canc Netw Volume: 10 Page(s): 1112 - 1150
  09/01/2012 Authors: Coccia PF; Altman J; Bhatia S; Borinstein SC; Flynn J; George S; Goldsby R; Hayashi R; Huang MS; Johnson RH
• WHIM syndrome caused by a single amino acid substitution in the carboxy-tail of chemokine receptor CXCR4.
  Blood Volume: 120 Page(s): 181 - 189
  07/05/2012 Authors: Liu Q; Chen H; Ojode T; Gao X; Anaya-O'Brien S; Turner NA; Ulrick J; DeCastro R; Kelly C; Cardones AR
• IRON DEPRIVATION IMPAIRS PROLIFERATION OF CALM-AF10 LEUKEMIA IN VITRO AND IN VIVO
  Volume: 58 Page(s): 1039 - 1039
  07/01/2012 Authors: Heath J; Lavau C; Scotland P; Wechsler D
• MXI1 AND N-MYC INDUCE NEUROBLASTOMA CELL APOPTOSIS VIA DISTINCT PATHWAYS
  Volume: 58 Page(s): 1077 - 1077
  07/01/2012 Authors: Armstrong M; Hill A; Wechsler D
• Successful treatment of disseminated cryptococcal infection in a pediatric acute lymphoblastic leukemia patient during induction.
  J Pediatr Hematol Oncol Volume: 34 Page(s): e161 - e163
  05/01/2012 Authors: Heath JL; Yin DE; Wechsler DS; Turner DA
• Nuclear export of CALM-AF10 is essential for leukemogenesis
  Volume: 72
  04/15/2012 Authors: Conway AE; Scotland PB; Lavau CP; Wechsler DS
• MLL duplication in a pediatric patient with B-cell lymphoblastic lymphoma.
  J Pediatr Hematol Oncol Volume: 34 Page(s): e120 - e123
  04/01/2012 Authors: Mater DV; Goodman BK; Wang E; Gaca AM; Wechsler DS
• The PICALM protein plays a key role in iron homeostasis and cell proliferation.
  PLoS One Volume: 7 Page(s): e44252
  01/01/2012 Authors: Scotland PB; Heath JL; Conway AE; Porter NB; Armstrong MB; Walker JA; Klebig ML; Lavau CP; Wechsler DS
• CALM Insufficiency Impairs Leukemia Cell Proliferation by Limiting Iron Uptake
  Volume: 118 Page(s): 642 - 642
  11/18/2011 Authors: Lavau CP; Heath JL; Scotland PB; Wechsler DS
• MXI1, A MEMBER OF THE MAD PROTEIN FAMILY, ANTAGONIZES N-MYC DEPENDENT APOPTOSIS AND PROLIFERATION IN NEUROBLASTOMA CELLS
  Volume: 56 Page(s): 960 - 960
  06/01/2011 Authors: Armstrong M; Erichsen D; Wechsler D
• PERTURBED IRON METABOLISM IN CALM-DEFICIENT CELLS
  Volume: 56 Page(s): 921 - 921
  06/01/2011 Authors: Heath J; Scotland P; Walker J; Lavau C; Wechsler D
• Synchronous occurrence of metastatic Wilms tumor and ganglioneuroma.
  Pediatr Blood Cancer Volume: 55 Page(s): 562 - 565
  09/01/2010 Authors: Moran C; Greiner RJ; Mardam-Bey SW; Hollingsworth CL; Kulbacki E; Wechsler DS
• CALM DEFICIENCY ALTERS EXPRESSION AND ENDOCYTOSIS OF GROWTH FACTOR RECEPTORS
  Volume: 54 Page(s): 817 - 817
  06/01/2010 Authors: Wechsler D; Scotland P; Conway A; Lavau C
• (POSTER 151) MECHANISMS OF CALM-DEPENDENT LEUKEMOGENESIS: CALM FUSION PROTEINS UPREGULATE EXPRESSION OF THE IL-3 GROWTH FACTOR RECEPTOR
  Volume: 52 Page(s): 715 - 716
  06/01/2009 Authors: Walker JA; Wechsler DS; Lavau CP
• DISSECTING THE ROLE OF CALM IN LEUKEMOGENESIS: ELUCIDATION OF FUNCTIONAL DOMAINS REQUIRED FOR CLATHRIN-DEPENDENT ENDOCYTOSIS
  Volume: 52 Page(s): 714 - 715
  06/01/2009 Authors: Scotland PB; Conway AE; Brooks NL; Lavau CP; Wechsler DS
• MECHANISMS OF CALM-DEPENDENT ACUTE MYELOID LEUKEMOGENESIS: DEVELOPMENT OF CALM-INDUCIBLE CELL LINES
  Volume: 52 Page(s): 722 - 722
  06/01/2009 Authors: Greiner RJ; Goldstein SA; Scotland PB; Lavau CP; Wechsler DS
• Dissecting the role of CALM in leukemogenesis: Identification of a functional domain required for clathrin-dependent endocytosis
  Volume: 69
  05/01/2009 Authors: Scotland P; Conway A; Brooks N; Lavau C; Wechsler D
• Treatment with sirolimus results in complete responses in patients with autoimmune lymphoproliferative syndrome.
  Br J Haematol Volume: 145 Page(s): 101 - 106
  04/01/2009 Authors: Teachey DT; Greiner R; Seif A; Attiyeh E; Bleesing J; Choi J; Manno C; Rappaport E; Schwabe D; Sheen C
• Complete Responses in Patients with Autoimmune Lymphoproliferative Syndrome (ALPS) Using the mTOR Inhibitor Sirolimus (rapamycin).
  Volume: 112 Page(s): 891 - 892
  11/16/2008 Authors: Teachey DT; Greiner RJ; Schwabe D; Bleesing J; Manno CS; Sullivan K; Wechsler DS; Grupp SA
• Perturbed endocytosis as a mechanism of CALM-dependent leukemogenesis: Identification of specific CALM domains required for internalization and demonstration of prolonged JAK2 signaling in response to GM-CSF
  Volume: 110 Page(s): 538A - 538A
  11/16/2007 Authors: Brooks NL; Erichsen DA; Wechsler DS
• Consensus on a core curriculum in American training programs in pediatric hematology-oncology: a report from the ASPHO Training Committee.
  Pediatr Hematol Oncol Volume: 24 Page(s): 503 - 512
  01/01/2007 Authors: Hastings C; Wechsler DS; Stine KC; Graham DK; Abshire T
• Perturbed endocytosis by leukemogenic CALM-containing fusion proteins is associated with prolonged growth factor signaling and enhanced cellular proliferation.
  Volume: 106 Page(s): 696A - 696A
  11/16/2005 Authors: Chao MM; Erichsen DA; Krajewski ML; Bohlander SK; Wechsler DS
• Utility of cranial boost in addition to total body irradiation in the treatment of high risk acute lymphoblastic leukemia.
  Int J Radiat Oncol Biol Phys Volume: 63 Page(s): 1191 - 1196
  11/15/2005 Authors: Alexander BM; Wechsler D; Braun TM; Levine J; Herman J; Yanik G; Hutchinson R; Pierce LJ
• Burkitt lymphoma in a child with osteogenesis imperfecta.
  Pediatr Blood Cancer Volume: 45 Page(s): 863 - 864
  11/01/2005 Authors: Choi SW; Wechsler DS
• Early diagnosis remains the most reliable way to cure children with melanoma.
  Pediatr Blood Cancer Volume: 45 Page(s): 355
  09/01/2005 Authors: Bono A; Ferrari A
• Early diagnosis remains the most reliable way to cure chidren with melanoma: Response
  PEDIATRIC BLOOD & CANCER Volume: 45 Page(s): 356 - 356
  09/01/2005 Authors: Chao MM; Wechsler DS
• Aortobronchial fistula in a pediatric patient with massive hemoptysis: treatment by means of an aortic endograft.
  Ann Thorac Surg Volume: 80 Page(s): 731 - 733
  08/01/2005 Authors: Khare RK; Settimi PD; Mba NI; Wechsler DS; Bratton SL; Williams DM
• Testicular chloroma in a nonleukemic infant.
  Volume: 27 Page(s): 393 - 396
  07/01/2005 Authors: Armstrong MB; Nafiu OO; Valdez R; Park JM; Williams JA; Wechsler DS
• High-risk surgically resected pediatric melanoma and adjuvant interferon therapy.
  Pediatr Blood Cancer Volume: 44 Page(s): 441 - 448
  05/01/2005 Authors: Chao MM; Schwartz JL; Wechsler DS; Thornburg CD; Griffith KA; Williams JA
• Mechanisms of leukemic transformation by MLL-CALM: Identification of a CALM-derived transcriptional regulatory domain
  Volume: 19 Page(s): A875 - A875
  03/04/2005 Authors: Fox EJ; Chao MM; Wechsler D
• Perturbed endocytosis by CALM-containing fusion proteins: A leukemogenic mechanism in AML.
  Volume: 104 Page(s): 922A - 923A
  11/16/2004 Authors: Chao MM; Walker AC; Pendergast MB; Bohlander SK; Wechsler DS
• Mechanisms of leukemogenesis by MLL-CALM: Characterization of a CALM-derived transcriptional regulatory domain.
  Volume: 104 Page(s): 924A - 924A
  11/16/2004 Authors: Chao MM; Fox EJ; Wechsler DS
• Metastatic neuroblastoma presenting with binocular blindness from intracranial compression of the optic nerves.
  J Neuroophthalmol Volume: 24 Page(s): 119 - 124
  06/01/2004 Authors: Lau JJC; Trobe JD; Ruiz RE; Cho RW; Wechsler DS; Shah GV; Gebarski SS
• Differential expression of Mxi0 and MAi1 isoforms in cell differentiation and proliferation
  Volume: 55 Page(s): 300A - 300A
  04/01/2004 Authors: Zheng D; Wechsler DS
• Mechanisms of leukemic transformation by MLL-CALM: A CALM-derived transcriptional regulatory domain modulates MLL transcriptional activity
  Volume: 55 Page(s): 296A - 296A
  04/01/2004 Authors: Chao MM; Walker AC; Luo RT; Thirman MJ; Wechsler DS
• Role of cranial boost in addition to total body irradiation in the treatment of high risk acute lymphoblastic leukemia
  Volume: 60 Page(s): S564 - S564
  01/01/2004 Authors: Alexander B; Wechsler D; Herman J; Braun T; Yanik G; Hutchinson R; Levine J; Pierce L
• Mxi1-0, an alternatively transcribed Mxi1 isoform, is overexpressed in glioblastomas.
  Neoplasia Volume: 6 Page(s): 660 - 673
  01/01/2004 Authors: Engstrom LD; Youkilis AS; Gorelick JL; Zheng D; Ackley V; Petroff CA; Benson LQ; Coon MR; Zhu X; Hanash SM
• MLL-CALM inhibits clathrin-dependent endocytosis and confers a growth advantage in FL5.12 cells.
  Volume: 102 Page(s): 850A - 850A
  11/16/2003 Authors: Chao MM; Walker AC; Wechsler DS
• Characterization of gene expression profiles associated with glioma progression using oligonucleotide-based microarray analysis and real-time reverse transcription-polymerase chain reaction.
  Am J Pathol Volume: 163 Page(s): 1033 - 1043
  09/01/2003 Authors: van den Boom J; Wolter M; Kuick R; Misek DE; Youkilis AS; Wechsler DS; Sommer C; Reifenberger G; Hanash SM
• Inhibition of endocytosis by MLL-CALM, a novel fusion protein in infant acute myeloid leukemia
  Volume: 53 Page(s): 288A - 288A
  04/01/2003 Authors: Walker AC; Chao MM; Wechsler DS
• Refractory iron deficiency anemia as the primary clinical manifestation of celiac disease.
  J Pediatr Hematol Oncol Volume: 25 Page(s): 169 - 172
  02/01/2003 Authors: Mody RJ; Brown PI; Wechsler DS
• A novel chromosomal inversion at 11q23 in infant acute myeloid leukemia fuses MLL to CALM, a gene that encodes a clathrin assembly protein.
  Genes Chromosomes Cancer Volume: 36 Page(s): 26 - 36
  01/01/2003 Authors: Wechsler DS; Engstrom LD; Alexander BM; Motto DG; Roulston D
• Mediastinal seminoma in a patient with Wiskott-Aldrich syndrome.
  Volume: 24 Page(s): 672 - 676
  11/01/2002 Authors: Snyder KM; Rubin MA; Shulkin BL; Hutchinson RJ; Wechsler DS
• Differential regulation of MXI1 isoforms by N-MYC neuroblastoma
  Volume: 51 Page(s): 232A - 232A
  04/01/2002 Authors: Mody RJ; Engstrom LD; So NC; Wechsler DS
• A novel inversion of chromosome 11 in infant acute myeloid leukemia fuses MLL to Calm, a clathrin assembly protein gene.
  Volume: 98 Page(s): 576A - 577A
  11/16/2001 Authors: Alexander BM; Engstrom LD; Motto DG; Roulston D; Wechsler DS
• Characterisation of gene expression profiles associated with glioma progression using oligonucleotide-based microarray analysis
  Volume: 102 Page(s): 547 - 547
  11/01/2001 Authors: Wolter M; van den Boom J; Misek D; Kuick R; Youkilis A; Wechsler D; Reifenberger G; Hanash S
• Mxi1, a Myc antagonist, suppresses proliferation of DU145 human prostate cells.
  Prostate Volume: 47 Page(s): 194 - 204
  05/15/2001 Authors: Taj MM; Tawil RJ; Engstrom LD; Zeng Z; Hwang C; Sanda MG; Wechsler DS
• Expression of MXI1, a Myc antagonist, is regulated by Sp1 and AP2.
  J Biol Chem Volume: 274 Page(s): 28794 - 28802
  10/01/1999 Authors: Benson LQ; Coon MR; Krueger LM; Han GC; Sarnaik AA; Wechsler DS
• MXI1, a putative tumor suppressor gene, suppresses growth of human glioblastoma cells.
  Cancer Res Volume: 57 Page(s): 4905 - 4912
  11/01/1997 Authors: Wechsler DS; Shelly CA; Petroff CA; Dang CV
• The MXI1 tumor suppressor gene is regulated by a tata-less promoter
  Volume: 88 Page(s): 3169 - 3169
  11/15/1996 Authors: Quinn LM; Sarnaik A; Wechsler DS
• Hemolysis following coil embolization of a patent ductus arteriosus.
  Cathet Cardiovasc Diagn Volume: 39 Page(s): 287 - 290
  11/01/1996 Authors: Shim D; Wechsler DS; Lloyd TR; Beekman RH
• Genomic organization of human MXI1, a putative tumor suppressor gene.
  Genomics Volume: 32 Page(s): 466 - 470
  03/15/1996 Authors: Wechsler DS; Shelly CA; Dang CV
• Gene structure of MXI1, a putative tumor suppressor gene.
  Volume: 86 Page(s): 646 - 646
  11/15/1995 Authors: Wechsler DS; Dang CV
• TaqI polymorphism of the human MXI1 gene.
  Volume: 3 Page(s): 2266
  12/01/1994 Authors: Bova GS; Wechsler DS; Van Dang C; Isaacs WB
• Anti-Hu antibody in a neuroblastoma-associated paraneoplastic syndrome.
  Pediatr Neurol Volume: 10 Page(s): 309 - 312
  06/01/1994 Authors: Fisher PG; Wechsler DS; Singer HS
• Differential binding of c-Myc and Max to nucleosomal DNA.
  Mol Cell Biol Volume: 14 Page(s): 4097 - 4107
  06/01/1994 Authors: Wechsler DS; Papoulas O; Dang CV; Kingston RE
• Localization of the human Mxi1 transcription factor gene (MXI1) to chromosome 10q24-q25.
  Genomics Volume: 21 Page(s): 669 - 672
  06/01/1994 Authors: Wechsler DS; Hawkins AL; Li X; Jabs EW; Griffin CA; Dang CV
• Cytogenetic abnormalities in two cases of neuroblastoma.
  Cancer Genet Cytogenet Volume: 74 Page(s): 30 - 34
  05/01/1994 Authors: Lo R; Perlman E; Hawkins AL; Hayashi R; Wechsler DS; Look AT; Griffin CA
• Yersinia enterocolitica infection in a patient with sickle cell disease after exposure to chitterlings.
  Am J Pediatr Hematol Oncol Volume: 16 Page(s): 153 - 155
  05/01/1994 Authors: Stoddard JJ; Wechsler DS; Nataro JP; Casella JF
• Resolution of nephrocalcinosis associated with tumor lysis syndrome.
  Pediatr Hematol Oncol Volume: 11 Page(s): 115 - 118
  01/01/1994 Authors: Wechsler DS; Kastan MB; Fivush BA
• Dermatitis as a presenting sign of cystic fibrosis.
  Arch Dermatol Volume: 128 Page(s): 1358 - 1364
  10/01/1992 Authors: Darmstadt GL; Schmidt CP; Wechsler DS; Tunnessen WW; Rosenstein BJ
• Opposite orientations of DNA bending by c-Myc and Max.
  Proc Natl Acad Sci U S A Volume: 89 Page(s): 7635 - 7639
  08/15/1992 Authors: Wechsler DS; Dang CV
• DNA binding by the Myc oncoproteins.
  Cancer Treat Res Volume: 63 Page(s): 313 - 325
  01/01/1992 Authors: Kato GJ; Wechsler DS; Dang CV
• Apparent proteinuria as a consequence of sodium bicarbonate ingestion.
  Pediatrics Volume: 86 Page(s): 318 - 319
  08/01/1990 Authors: Wechsler D; Ibsen L; Fosarelli P
• Further characterization of the curative antibodies in Trypanosoma musculi infection.
  Infect Immun Volume: 56 Page(s): 2379 - 2384
  09/01/1988 Authors: Wechsler DS; Kongshavn PA
• Heat-labile IgG2a antibodies affect cure of Trypanosoma musculi infection in C57BL/6 mice.
  J Immunol Volume: 137 Page(s): 2968 - 2972
  11/01/1986 Authors: Wechsler DS; Kongshavn PA
• In vitro assay for curative activity in blood of mice infected with Trypanosoma musculi.
  Infect Immun Volume: 53 Page(s): 240 - 244
  08/01/1986 Authors: Wechsler DS; Kongshavn PA
• Characterization of antibodies mediating protection and cure of Trypanosoma musculi infection in mice.
  Infect Immun Volume: 48 Page(s): 787 - 794
  06/01/1985 Authors: Wechsler DS; Kongshavn PA
• Cure of Trypanosoma musculi infection by heat-labile activity in immune plasma.
  Infect Immun Volume: 44 Page(s): 756 - 759
  06/01/1984 Authors: Wechsler DS; Kongshavn PA
• CHARACTERIZATION OF THERMOLABILE CURATIVE ACTIVITY IN PLASMA OF MICE INFECTED WITH TRYPANOSOMA MUSCULI
  Volume: 36 Page(s): 399 - 399
  01/01/1984 Authors: WECHSLER DS; KONGSHAVN PAL
• MECHANISMS OF PROTECTIVE IMMUNITY IN MURINE TRYPANOSOMIASIS - ELIMINATION OF BLOOD PARASITEMIA INVOLVES CELLULAR MECHANISM
  Volume: 41 Page(s): 581 - 581
  01/01/1982 Authors: KONGSHAVN PAL; STCHARLES C; WECHSLER D; RAPPATONI W; GHADIRIAN E