Debra Saxe PhD
Academic Appointment
- Associate Professor /Adjunct Professor, Emory University School of Medicine
- Associate Professor, Department of Pathology and Laboratory Medicine, Emory University School of Medicine
- Associate Professor /Adjunct Professor, Emory University School of Medicine
Education
Degrees
- PhD from University of Arizona
- BA from University of Texas
- MS from University of Arizona
Research
Focus
- I am collaborating with Emory Biomarker Service Center to develop a single nucleotide polymorphic (SNP) microarray for leukemias and lymphomas that can be transitioned into clinical use. I am also a co-investigator on a study to correlate flourescent in situ hybridation (FISH) and whole genome analysis on specific lung tumors with disease progression and response to therapies. I am developing cytogenomic microarray testing for clinical use in oncology.
Publications
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Transposon DNA sequences facilitate the tissue-specific gene transfer of circulating tumor DNA between human cells.
Nucleic Acids Res Volume: 52 Page(s): 7539 - 7555
07/22/2024 Authors: Cinar M; Martinez-Medina L; Puvvula PK; Arakelyan A; Vardarajan BN; Anthony N; Nagaraju GP; Park D; Feng L; Sheff F -
Loss of heterozygosity leading to incorrect HLA typing for platelet-transfusion refractory patient.
Volume: 63 Page(s): 263 - 268
01/01/2023 Authors: Horwath M; Tvrdik T; Saxe D; Deeb KK; Roback JD; Gebel HM; Bray RA; Sullivan HC -
Clinical Validation and Diagnostic Utility of Optical Genome Mapping for Enhanced Cytogenomic Analysis of Hematological Neoplasms.
J Mol Diagn Volume: 24 Page(s): 1279 - 1291
12/01/2022 Authors: Sahajpal NS; Mondal AK; Tvrdik T; Hauenstein J; Shi H; Deeb KK; Saxe D; Hastie AR; Chaubey A; Savage NM -
Cryptic t(6;11) KMT2A rearrangement in a pediatric acute myeloid leukemia patient detected by next-generation sequencing and dual-fusion FISH analysis.
Pediatr Blood Cancer Volume: 69 Page(s): e29428
03/01/2022 Authors: Raghunandan S; Jain J; Saxe D; Pauly M; Aljudi AA; Ketterling RP; Carter AB; Raikar SS -
Sustained Complete Molecular Remission With Imatinib Monotherapy in a Child Presenting With Blast Phase FIP1L1-PDGFRA-Associated Myeloid Neoplasm With Eosinophilia.
Hemasphere Volume: 4 Page(s): e486
12/01/2020 Authors: Jain J; Weinzierl EP; Saxe D; Bergsagel J; Gotlib J; Reiter A; Raikar SS -
Copy number assessment in the genomic analysis of CNS neoplasia: An evidence-based review from the cancer genomics consortium (CGC) working group on primary CNS tumors.
Cancer Genet Volume: 243 Page(s): 19 - 47
05/01/2020 Authors: Neill SG; Hauenstein J; Li MM; Liu YJ; Luo M; Saxe DF; Ligon AH -
Genomic copy number variation correlates with survival outcomes in WHO grade IV glioma.
Sci Rep Volume: 10 Page(s): 7355
04/30/2020 Authors: Buchwald ZS; Tian S; Rossi M; Smith GH; Switchenko J; Hauenstein JE; Moreno CS; Press RH; Prabhu RS; Zhong J -
Clonal Evolution of B-Cell Acute Lymphoblastic Leukemia with del(9)(p13p21) into Mixed Phenotype Acute Leukemia Presenting as an Isolated Testicular Relapse.
Reports (MDPI) Volume: 2
09/01/2019 Authors: Miller LH; Park SI; Saxe D; Lew G; Raikar SS -
Gliosarcoma: distinct molecular pathways and genomic alterations identified by DNA copy number/SNP microarray analysis.
J Neurooncol Volume: 143 Page(s): 381 - 392
07/01/2019 Authors: Lowder L; Hauenstein J; Woods A; Chen H-R; Rupji M; Kowalski J; Olson JJ; Saxe D; Schniederjan M; Neill S -
Evaluating approaches to enhance survival in children with hypodiploid acute lymphoblastic leukaemia (ALL).
Br J Haematol Volume: 185 Page(s): 613 - 616
05/01/2019 Authors: Miller L; Kobayashi S; Pauly M; Lew G; Saxe D; Keller F; Qayed M; Castellino S