Publications

• piv does not impact Pseudomonas aeruginosa virulence in Galleria mellonella.
  Microbiol Spectr Page(s): e0281124
  05/21/2025 Authors: Robinson RE; Robertson JK; Moustafa DA; Goldberg JB
• Monoclonal antibodies derived from B cells in subjects with cystic fibrosis reduce Pseudomonas aeruginosa burden in mice.
  Elife Volume: 13
  04/24/2025 Authors: Hale M; Takehara KK; Thouvenel CD; Moustafa DA; Repele A; Fontana MF; Netland J; McNamara S; Gibson RL; Goldberg JB
• RNA-seq reproducibility of Pseudomonas aeruginosa in laboratory models of cystic fibrosis.
  Microbiol Spectr Volume: 13 Page(s): e0151324
  01/07/2025 Authors: Duncan RP; Lewin GR; Cornforth DM; Diggle FL; Kapur A; Moustafa DA; Hilliam Y; Bomberger JM; Whiteley M; Goldberg JB
• Pseudomonas aeruginosa elongation factor-Tu (EF-Tu) is an immunogenic protective protein antigen.
  Vaccine Volume: 42 Page(s): 126476
  12/02/2024 Authors: Moustafa DA; Lou E; Schafer-Kestenman ME; Mateu-Borrs M; Domnech-Sanchez A; Albert S; Goldberg JB
• Serotype switching in Pseudomonas aeruginosa ST111 enhances adhesion and virulence.
  PLoS Pathog Volume: 20 Page(s): e1012221
  12/01/2024 Authors: Anbo M; Lubna MA; Moustafa DA; Paiva TO; Serioli L; Zor K; Sternberg C; Jeannot K; Ciofu O; Dufrne YF
• Characterization of Pseudomonas aeruginosa from subjects with diffuse panbronchiolitis.
  Microbiol Spectr Volume: 12 Page(s): e0053024
  11/05/2024 Authors: Met CM; Hofstaedter CE; O'Keefe IP; Yang H; Moustafa DA; Sherman ME; Doi Y; Rasko DA; Sweet CR; Goldberg JB
• Monoclonal antibodies derived from B cells in subjects with cystic fibrosis reduce Pseudomonas aeruginosa burden in mice.
  bioRxiv
  10/09/2024 Authors: Hale M; Takehara KK; Thouvenel CD; Moustafa DA; Repele A; Fontana MF; Netland J; McNamara S; Gibson RL; Goldberg JB
• Flagellum-deficient Pseudomonas aeruginosa is more virulent than non-motile but flagellated mutants in a cystic fibrosis mouse model.
  Microbiol Spectr Volume: 12 Page(s): e0132524
  10/03/2024 Authors: Moustafa DA; Fantone KM; Tucker SL; McCarty NA; Stecenko AA; Goldberg JB; Rada B
• Chronic hyperglycemia aggravates lung function in a Scnn1b-Tg murine model.
  Am J Physiol Lung Cell Mol Physiol Volume: 327 Page(s): L473 - L486
  10/01/2024 Authors: Cui G; Moustafa DA; Zhao S; Cegla AV; Lyles JT; Goldberg JB; Chandler JD; McCarty NA
• Improvement of a mouse infection model to capture Pseudomonas aeruginosa chronic physiology in cystic fibrosis.
  Proc Natl Acad Sci U S A Volume: 121 Page(s): e2406234121
  08/13/2024 Authors: Duncan RP; Moustafa DA; Lewin GR; Diggle FL; Bomberger JM; Whiteley M; Goldberg JB
• Mutation of hmgA, encoding homogentisate 1,2-dioxygenase, is responsible for pyomelanin production but does not impact the virulence of Burkholderia cenocepacia in a chronic granulomatous disease mouse lung infection.
  Microbiol Spectr Volume: 12 Page(s): e0041024
  07/02/2024 Authors: Moustafa DA; Wu L; Ivey M; Fankhauser SC; Goldberg JB
• Efficacy of a Pseudomonas aeruginosa serogroup O9 vaccine.
  Infect Immun Volume: 91 Page(s): e0024723
  12/12/2023 Authors: Moustafa DA; DiGiandomenico A; Raghuram V; Schulman M; Scarff JM; Davis MR; Varga JJ; Dean CR; Goldberg JB
• Sequence specificity defines the effectiveness of PPMOs targeting Pseudomonas aeruginosa.
  Antimicrob Agents Chemother Volume: 67 Page(s): e0024523
  09/19/2023 Authors: Nanayakkara AK; Moustafa DA; Pifer R; Goldberg JB; Greenberg DE
• Efficacy of a Pseudomonas aeruginosa Serogroup O9 Vaccine.
  bioRxiv
  07/13/2023 Authors: Moustafa DA; DiGiandomenico A; Raghuram V; Schulman M; Scarff JM; Davis MR; Varga JJ; Dean CR; Goldberg JB
• A Pseudomonas aeruginosa small RNA regulates chronic and acute infection.
  Nature Volume: 618 Page(s): 358 - 364
  06/01/2023 Authors: Cao P; Fleming D; Moustafa DA; Dolan SK; Szymanik KH; Redman WK; Ramos A; Diggle FL; Sullivan CS; Goldberg JB
• Application of a quantitative framework to improve the accuracy of a bacterial infection model.
  Proc Natl Acad Sci U S A Volume: 120 Page(s): e2221542120
  05/09/2023 Authors: Lewin GR; Kapur A; Cornforth DM; Duncan RP; Diggle FL; Moustafa DA; Harrison SA; Skaar EP; Chazin WJ; Goldberg JB
• The PqsE Active Site as a Target for Small Molecule Antimicrobial Agents against Pseudomonas aeruginosa.
  Biochemistry Volume: 61 Page(s): 1894 - 1903
  09/06/2022 Authors: Taylor IR; Jeffrey PD; Moustafa DA; Goldberg JB; Bassler BL
• Bacteriophage-Loaded Poly(lactic-co-glycolic acid) Microparticles Mitigate Staphylococcus aureus Infection and Cocultures of Staphylococcus aureus and Pseudomonas aeruginosa.
  Adv Healthc Mater Volume: 11 Page(s): e2102539
  05/01/2022 Authors: Kalelkar PP; Moustafa DA; Riddick M; Goldberg JB; McCarty NA; Garca AJ
• Vfr or CyaB promote the expression of the pore-forming toxin exlBA operon in Pseudomonas aeruginosa ATCC 9027 without increasing its virulence in mice.
  Microbiology (Reading) Volume: 167
  08/01/2021 Authors: Garca-Reyes S; Moustafa DA; Attre I; Goldberg JB; Quiroz-Morales SE; Sobern-Chvez G
• Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers Retain Activity against Multidrug-Resistant Pseudomonas aeruginosa In Vitro and In Vivo.
  mBio Volume: 12
  01/12/2021 Authors: Moustafa DA; Wu AW; Zamora D; Daly SM; Sturge CR; Pybus C; Geller BL; Goldberg JB; Greenberg DE
• Modulation of Early Mitotic Inhibitor 1 (EMI1) depletion on the sensitivity of PARP inhibitors in BRCA1 mutated triple-negative breast cancer cells.
  PLoS One Volume: 16 Page(s): e0235025
  01/01/2021 Authors: Moustafa D; Elwahed MRA; Elsaid HH; Parvin JD
• Role of Pseudomonas aeruginosa Glutathione Biosynthesis in Lung and Soft Tissue Infection.
  Infect Immun Volume: 88
  05/20/2020 Authors: Michie KL; Dees JL; Fleming D; Moustafa DA; Goldberg JB; Rumbaugh KP; Whiteley M
• The PqsE and RhlR proteins are an autoinducer synthase-receptor pair that control virulence and biofilm development in Pseudomonas aeruginosa.
  Proc Natl Acad Sci U S A Volume: 115 Page(s): E9411 - E9418
  10/02/2018 Authors: Mukherjee S; Moustafa DA; Stergioula V; Smith CD; Goldberg JB; Bassler BL
• GENE-SILENCING ANTISENSE OLIGOMERS: A NOVEL THERAPEUTIC APPROACH TO COMBAT MULTIDRUG RESISTANT PSEUDOMONAS AERUGINOSA IN VITRO AND IN VIVO
  Volume: 52 Page(s): S359 - S359
  09/01/2017 Authors: Moustafa DA; Zamora D; Daly S; Sturge C; Geller B; Goldberg J; Greenberg D
• The RhlR quorum-sensing receptor controls Pseudomonas aeruginosa pathogenesis and biofilm development independently of its canonical homoserine lactone autoinducer.
  PLoS Pathog Volume: 13 Page(s): e1006504
  07/01/2017 Authors: Mukherjee S; Moustafa D; Smith CD; Goldberg JB; Bassler BL
• Inhibition of Pseudomonas aeruginosa by Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers.
  Antimicrob Agents Chemother Volume: 61
  04/01/2017 Authors: Howard JJ; Sturge CR; Moustafa DA; Daly SM; Marshall-Batty KR; Felder CF; Zamora D; Yabe-Gill M; Labandeira-Rey M; Bailey SM
• Recombinant Salmonella Expressing Burkholderia mallei LPS O Antigen Provides Protection in a Murine Model of Melioidosis and Glanders.
  PLoS One Volume: 10 Page(s): e0132032
  01/01/2015 Authors: Moustafa DA; Scarff JM; Garcia PP; Cassidy SKB; DiGiandomenico A; Waag DM; Inzana TJ; Goldberg JB
• Identification of a single-nucleotide insertion in the promoter region affecting the sodC promoter activity in Brucella neotomae.
  PLoS One Volume: 5 Page(s): e14112
  11/24/2010 Authors: Moustafa DA; Jain N; Sriranganathan N; Vemulapalli R
• Prevalence of antibiotic resistance among Egyptian Salmonella typhi strains.
  J Egypt Public Health Assoc Volume: 71 Page(s): 149 - 160
  01/01/1996 Authors: Wasfy MO; Moustafa DA; El-Gendy AM; Mohran ZS; Ismail TF; El-Etr SH; Oyofo BA