David Jaye MD

Department of Pathology and Laboratory Medicine
Associate Professor

Overview

Dr. Jaye is an attending physician on the hematopathology service for Emory Healthcare and a consultant at Children's Healthcare of Atlanta and Grady Memorial Hospital. A board certified pathologist, he began practicing with Emory Healthcare in 2002.

Dr. Jaye is a member of the Cancer Immunology Research Program at Winship Cancer Institute of Emory University and has an extensive research background.

Education

Degrees

MD from Washington University School of Medicine
BA from University of California at San Diego
MA from Washington University School of Medicine

Research

Focus

Hematolymphoid neoplasms and disorders
I work, often collaboratively, on projects broadly related to biology, laboratory diagnosis and treatment of hematolymphoid neoplasms. Ongoing research endeavors include studies of B-lineage neoplasms (lymphoma, multiple myeloma) including clinico-pathologic correlations, machine-learning approaches to analysis of digital pathology slide images, and pathologic analysis of murine allogeneic transplant models.

Publications

Interleukin-1 receptor antagonist is a conserved early factor for exacerbating tuberculosis susceptibility.
bioRxiv
03/29/2025 Authors: Lee OV; Ji DX; Rosa BA; Jaye DL; Suliman S; Mitreva M; Gabay C; Vance RE; Kotov DI
Heme promotes venetoclax resistance in multiple myeloma through MEK-ERK signaling and purine biosynthesis.
Blood Volume: 145 Page(s): 732 - 747
02/13/2025 Authors: Nair R; Vu AH; Freer AK; Bhatia KS; Wang D; Savani MR; Matulis SM; Lonial S; Jaye DL; Boise LH
Real-world impact of differences in the WHO and ICC classifications of non-Hodgkin lymphoma: a LEO cohort study analysis.
Blood Volume: 144 Page(s): 2063 - 2066
11/07/2024 Authors: Abro B; Maurer MJ; Habermann TM; Burack WR; Chapman JR; Cohen JB; Friedberg JW; Inghirami G; Kahl BS; Larson MC
The unnecessary use of short tandem repeat testing on bone marrow samples in patients after 1 year following allogeneic hematopoietic stem cell transplant.
Am J Clin Pathol Volume: 162 Page(s): 464 - 470
11/04/2024 Authors: Morris AB; Sullivan HC; Wooten MS; Waller EK; Jaye DL
SAMHD1 expression contributes to doxorubicin resistance and predicts survival outcomes in diffuse large B-cell lymphoma patients.
NAR Cancer Volume: 6 Page(s): zcae007
03/01/2024 Authors: Daddacha W; Monroe D; Schlafstein AJ; Withers AE; Thompson EB; Danelia D; Luong NC; Sesay F; Rath SK; Usoro ER
The Lymphoma Epidemiology of Outcomes cohort study: Design, baseline characteristics, and early outcomes.
Am J Hematol Volume: 99 Page(s): 408 - 421
03/01/2024 Authors: Cerhan JR; Maurer MJ; Link BK; Feldman AL; Habermann TM; Jaye DL; Burack WR; McDonnell TJ; Vega F; Chapman JR
Translating prognostic quantification of c-MYC and BCL2 from tissue microarrays to whole slide images in diffuse large B-cell lymphoma using deep learning.
Diagn Pathol Volume: 19 Page(s): 17
01/19/2024 Authors: Tavolara TE; Niazi MKK; Feldman AL; Jaye DL; Flowers C; Cooper LAD; Gurcan MN
Automated Deep Learning-Based Diagnosis and Molecular Characterization of Acute Myeloid Leukemia Using Flow Cytometry.
Mod Pathol Volume: 37 Page(s): 100373
01/01/2024 Authors: Lewis JE; Cooper LAD; Jaye DL; Pozdnyakova O
Early cellular mechanisms of type I interferon-driven susceptibility to tuberculosis.
Cell Volume: 186 Page(s): 5536 - 5553.e22
12/07/2023 Authors: Kotov DI; Lee OV; Fattinger SA; Langner CA; Guillen JV; Peters JM; Moon A; Burd EM; Witt KC; Stetson DB
Profiling endogenous, environmental, and infectious disease mutational signatures in blastic plasmacytoid dendritic cell neoplasms.
Int J Lab Hematol Volume: 45 Page(s): 726 - 734
10/01/2023 Authors: Small C; Mukerjee S; Jangam D; Gollapudi S; Singh K; Jaye DL; Aung PP; Querfeld C; Yao K; Chisholm KM
Automated Deep Learning-Based Diagnosis and Molecular Characterization of Acute Myeloid Leukemia using Flow Cytometry.
bioRxiv
09/25/2023 Authors: Lewis JE; Cooper LAD; Jaye DL; Pozdnyakova O
Regulation of antigen-specific T cell infiltration and spatial architecture in multiple myeloma and premalignancy.
J Clin Invest Volume: 133
08/01/2023 Authors: Robinson MH; Villa NY; Jaye DL; Nooka AK; Duffy A; McCachren SS; Manalo J; Switchenko JM; Barnes S; Potdar S
An Analysis of the Pathologic Features of Blastic Plasmacytoid Dendritic Cell Neoplasm Based on a Comprehensive Literature Database of Cases.
Arch Pathol Lab Med Volume: 147 Page(s): 837 - 846
07/01/2023 Authors: Ohgami RS; Aung PP; Gru AA; Hussaini M; Singh K; Querfeld C; Yao K; Small C; Gollapudi S; Jaye D
ALK-negative anaplastic large cell lymphoma with JAK2 rearrangement mimicking classic Hodgkin lymphoma.
Blood Volume: 141 Page(s): 2160
04/27/2023 Authors: Jaye DL; Feldman AL
An Automated Pipeline for Differential Cell Counts on Whole-Slide Bone Marrow Aspirate Smears.
Mod Pathol Volume: 36 Page(s): 100003
02/01/2023 Authors: Lewis JE; Shebelut CW; Drumheller BR; Zhang X; Shanmugam N; Attieh M; Horwath MC; Khanna A; Smith GH; Gutman DA
Herpes simplex virus lymphadenitis is associated with tumor reduction in a patient with chronic lymphocytic leukemia.
J Clin Invest Volume: 132
09/15/2022 Authors: Chang A; Sholukh AM; Wieland A; Jaye DL; Carrington M; Huang M-L; Xie H; Jerome KR; Roychoudhury P; Greninger AL
Venetoclax ex vivo functional profiling predicts improved progression-free survival.
Blood Cancer J Volume: 12 Page(s): 115
08/04/2022 Authors: Gupta VA; Matulis SM; Barwick BG; Bog RD; Shebelut CW; Shanmugam M; Neri P; Bahlis NJ; Dhodapkar MV; Heffner LT
NuCLS: A scalable crowdsourcing approach and dataset for nucleus classification and segmentation in breast cancer.
Gigascience Volume: 11
05/17/2022 Authors: Amgad M; Atteya LA; Hussein H; Mohammed KH; Hafiz E; Elsebaie MAT; Alhusseiny AM; AlMoslemany MA; Elmatboly AM; Pappalardo PA
Erythropoietic properties of human induced pluripotent stem cells-derived red blood cells in immunodeficient mice.
Am J Hematol Volume: 97 Page(s): 194 - 202
02/01/2022 Authors: Deng J; Lancelot M; Jajosky R; Deng Q; Deeb K; Saakadze N; Gao Y; Jaye D; Liu S; Stowell SR
Lightweight, open source, easy-use algorithm and web service for paraprotein screening using spatial frequency domain analysis of electrophoresis studies.
J Pathol Inform Volume: 13 Page(s): 100128
01/01/2022 Authors: Chen R; Jaye DL; Roback JD; Sherman MA; Smith GH
Venetoclax sensitivity in multiple myeloma is associated with B-cell gene expression.
Blood Volume: 137 Page(s): 3604 - 3615
07/01/2021 Authors: Gupta VA; Barwick BG; Matulis SM; Shirasaki R; Jaye DL; Keats JJ; Oberlton B; Joseph NS; Hofmeister CC; Heffner LT
Chromatin Accessibility Identifies Regulatory Elements Predictive of Gene Expression and Disease Outcome in Multiple Myeloma.
Clin Cancer Res Volume: 27 Page(s): 3178 - 3189
06/01/2021 Authors: Barwick BG; Gupta VA; Matulis SM; Patton JC; Powell DR; Gu Y; Jaye DL; Conneely KN; Lin YC; Hofmeister CC
A Mimic of Posttransplant Lymphoproliferative Disease Following Liver Transplant.
Exp Clin Transplant Volume: 18 Page(s): 741 - 743
11/01/2020 Authors: Kitchens WH; Jaye DL; Wedd JP; Magliocca JF
Early Development of a Machine Learning Approach to Quantify MYC Immunohistochemical Staining in Lymphoma
Volume: 154 Page(s): S19 - S19
10/01/2020 Authors: Drumheller B; Amgad M; Aljudi A; Burdette E; Kutob L; Neely C; Perricone A; Shebelut C; Jaye D
Early Development of a Machine Learning Approach to Quantify MYC Immunohistochemical Staining in Lymphoma
Volume: 154 Page(s): S19 - S19
10/01/2020 Authors: Drumheller B; Amgad M; Aljudi A; Burdette E; Kutob L; Neely C; Perricone A; Shebelut C; Jaye D
Automated Serum Protein Electrophoresis Interpretation Using Machine Learning-Based Algorithm for Paraprotein Detection
Volume: 154 Page(s): S7 - S8
10/01/2020 Authors: Chen R; Jaye DL; Roback JD; Sherman MA; Smith GH
Clinician-ordered peripheral blood smears have low reimbursement and variable clinical value: a three-institution study, with suggestions for operational efficiency.
Diagn Pathol Volume: 15 Page(s): 112
09/17/2020 Authors: Beckman AK; Ng VL; Jaye DL; Gaddh M; Williams SA; Yohe SL; Zhang L; Linden MA
Clinical features and survival of multiple myeloma patients harboring t(14;16) in the era of novel agents.
Blood Cancer J Volume: 10 Page(s): 40
04/14/2020 Authors: Mina R; Joseph NS; Gay F; Kastritis E; Petrucci MT; Kaufman JL; Montefusco V; Gavriatopoulou M; Patriarca F; Omed P
Rituximab leads to early elimination of circulating CD20+ T and B lymphocytes in patients with iTTP despite ongoing TPEx.
Blood Adv Volume: 4 Page(s): 477 - 481
02/11/2020 Authors: Carden MA; Gaddh M; Hoskote A; Brown M; Merrill V; Stowell SR; Chandrakasan S; Antun A; Kudchadkar R; Kotanchiyev S
Machine-based detection and classification for bone marrow aspirate differential counts: initial development focusing on nonneoplastic cells.
Lab Invest Volume: 100 Page(s): 98 - 109
01/01/2020 Authors: Chandradevan R; Aljudi AA; Drumheller BR; Kunananthaseelan N; Amgad M; Gutman DA; Cooper LAD; Jaye DL
Retroperitoneal Follicular Dendritic Cell Sarcoma: A Case Report.
Adv Radiat Oncol Volume: 5 Page(s): 297 - 300
01/01/2020 Authors: Jiang C; Syed YA; Burdette EB; Jaye DL; Flowers CR; Khan MK
Gain of Chromosome 1q is associated with early progression in multiple myeloma patients treated with lenalidomide, bortezomib, and dexamethasone.
Blood Cancer J Volume: 9 Page(s): 94
11/25/2019 Authors: Schmidt TM; Barwick BG; Joseph N; Heffner LT; Hofmeister CC; Bernal L; Dhodapkar MV; Gupta VA; Jaye DL; Wu J
Whole Exome and Transcriptome Sequencing in 1042 Cases Reveals Distinct Clinically Relevant Genetic Subgroups of Follicular Lymphoma.
Blood Volume: 134 Page(s): 19
11/13/2019 Authors: Li X; Kositsky R; Reddy A; Love C; Naresh K; Koff JL; Nystrand I; Lepp S; Pasanen A; Karjalainen-Lindsberg M-L
The (Un)Necessary Use of Short-Tandem-Repeat (STR) Testing on Bone Marrow Samples in Patients After 1 Year Postallogeneic Hematopoietic Stem Cell Transplant
Volume: 152 Page(s): S8 - S8
10/01/2019 Authors: Wooten M; Sullivan HC; Jaye D
Flt3L Treatment of Bone Marrow Donors Increases Graft Plasmacytoid Dendritic Cell Content and Improves Allogeneic Transplantation Outcomes.
Biol Blood Marrow Transplant Volume: 25 Page(s): 1075 - 1084
06/01/2019 Authors: Hassan M; Ulezko Antonova A; Li JM; Hosoba S; Rupji M; Kowalski J; Perricone AJ; Jaye DL; Marsh H; Yellin M
Multiple myeloma immunoglobulin lambda translocations portend poor prognosis.
Nat Commun Volume: 10 Page(s): 1911
04/23/2019 Authors: Barwick BG; Neri P; Bahlis NJ; Nooka AK; Dhodapkar MV; Jaye DL; Hofmeister CC; Kaufman JL; Gupta VA; Auclair D
Oligoclonal T Cells Transiently Expand and Express Tim-3 and PD-1 Following Anti-CD19 CAR T Cell Therapy: A Case Report.
Int J Mol Sci Volume: 19
12/19/2018 Authors: Funk CR; Petersen CT; Jagirdar N; Ravindranathan S; Jaye DL; Flowers CR; Langston A; Waller EK
Early Experience in Developing a Machine-Learning and Digital Pathology Approach to Automate Bone Marrow Differential Counts
Volume: 150 Page(s): S149 - S150
10/01/2018 Authors: Abdulrahman A; Amgad M; Cooper L; Jaye D
Is a 500-Cell Count Necessary for Bone Marrow Differentials?: A Proposed Analytical Method for Validating a Lower Cutoff.
Am J Clin Pathol Volume: 150 Page(s): 84 - 91
05/31/2018 Authors: Abdulrahman AA; Patel KH; Yang T; Koch DD; Sivers SM; Smith GH; Jaye DL
Prevalence and clinical correlates of vulnerable status using the Vulnerable Elders Survey 13 (VES-13) in newly diagnosed adult non-Hodgkin lymphoma (NHL) patients: A LEO cross-sectional analysis.
Volume: 36
05/20/2018 Authors: Fama A; Martin P; Casulo C; Nastoupil LJ; Thompson CA; Link BK; Lossos IS; Kahl B; Maurer M; Allmer C
Isolated myeloperoxidase expression in pediatric B/myeloid mixed phenotype acute leukemia is linked with better survival.
Blood Volume: 131 Page(s): 573 - 577
02/01/2018 Authors: Raikar SS; Park SI; Leong T; Jaye DL; Keller FG; Horan JT; Woods WG
Informatics Approaches to Address New Challenges in the Classification of Lymphoid Malignancies.
JCO Clin Cancer Inform Volume: 2
01/01/2018 Authors: Jordan J; Goldstein JS; Jaye DL; Gurcan M; Flowers CR; Cooper LAD
Diagnosis of GATA2 haplo-insufficiency in a young woman prompted by pancytopenia with deficiencies of B-cell and dendritic cell development.
Biomark Res Volume: 6 Page(s): 13
01/01/2018 Authors: Sanyi A; Jaye DL; Rosand CB; Box A; Shanmuganathan C; Waller EK
Isolated Myeloperoxidase Expression in Pediatric B/Myeloid Mixed Phenotype Acute Leukemia Is Associated with Improved Survival Using ALL-Only Regimens
Volume: 130
12/07/2017 Authors: Raikar SS; Park S; Leong T; Jaye DL; Keller FG; Horan JT; Woods WG
CD303 Positive Plasmacytoid Dendritic Cells in Mycobacteria-Associated Granulomatous Inflammation
Volume: 147 Page(s): S161 - +
03/01/2017 Authors: Moon A; Burd E; Jaye D
CD303 Positive Plasmacytoid Dendritic Cells in Mycobacteria-Associated Granulomatous Inflammation.
Am J Clin Pathol Volume: 147 Page(s): S164 - S165
03/01/2017 Authors: Moon A; Burd E; Jaye D
Is a 500 Cell Bone Marrow Differential Count Necessary?
Am J Clin Pathol Volume: 147 Page(s): S27
03/01/2017 Authors: Patel K; Smith G; Koch D; Sivers S; Jaye D
Multimodality Technologies in the Assessment of Hematolymphoid Neoplasms.
Arch Pathol Lab Med Volume: 141 Page(s): 341 - 354
03/01/2017 Authors: Li S; Jaye DL; Bradley KT; Zhang L; Saxe D; Deeb G; Hill CE; Mann KP
PD-1 and CTLA-4 up regulation on donor T cells is insufficient to prevent GvHD in allo-HSCT recipients.
PLoS One Volume: 12 Page(s): e0184254
01/01/2017 Authors: Hossain MS; Kunter GM; El-Najjar VF; Jaye DL; Al-Kadhimi Z; Taofeek OK; Li J-M; Waller EK
Bortezomib-induced heat shock response protects multiple myeloma cells and is activated by heat shock factor 1 serine 326 phosphorylation.
Oncotarget Volume: 7 Page(s): 59727 - 59741
09/13/2016 Authors: Shah SP; Nooka AK; Jaye DL; Bahlis NJ; Lonial S; Boise LH
Identification of human plasma cells with a lamprey monoclonal antibody.
JCI Insight Volume: 1
01/01/2016 Authors: Yu C; Liu Y; Chan JTH; Tong J; Li Z; Shi M; Davani D; Parsons M; Khan S; Zhan W
A Phase 2 Trial of Fludarabine Combined With Subcutaneous Alemtuzumab for the Treatment of Relapsed/Refractory B-Cell Chronic Lymphocytic Leukemia.
Clin Lymphoma Myeloma Leuk Volume: 15 Page(s): 694 - 698
11/01/2015 Authors: Flowers CR; Brown JR; Rosenthal H; Stock W; Katzen HI; Cohen JB; Sinha R; Lakhanpal S; Leis JF; Waller EK
Improving Test Utilization for Chimerism Analysis After Hematopoietic Stem Cell Transplantation
Volume: 143 Page(s): A48 - A48
05/01/2015 Authors: Stelton C; Geller R; Waller E; Langston A; Gebel H; Jaye D
Successful treatment of severe immune hemolytic anemia after allogeneic stem cell transplantation with bortezomib: report of a case and review of literature.
Transfusion Volume: 55 Page(s): 259 - 264
02/01/2015 Authors: Hosoba S; Jaye DL; Cohen C; Roback JD; Waller EK
A LAMPREY MONOCLONAL VLR ANTIBODY RECOGNIZES A NOVEL PLASMA CELL ANTIGEN
JOURNAL OF MEDICAL PRIMATOLOGY Volume: 43 Page(s): 406 - 406
10/01/2014 Authors: Yu C; Herrin BR; Jaye DL; Cooper MD; Ehrhardt GRA
Sensitivity and specificity of cerebrospinal fluid flow cytometry for the diagnosis of leukemic meningitis in acute lymphoblastic leukemia/lymphoma.
Leuk Lymphoma Volume: 55 Page(s): 1498 - 1500
07/01/2014 Authors: Mitri Z; Siddiqui MT; El Rassi F; Holden JT; Heffner LT; Langston A; Waller EK; Winton E; McLemore M; Bernal-Mizrachi L
DNA methylation profiling in human B cells reveals immune regulatory elements and epigenetic plasticity at Alu elements during B-cell activation.
Genome Res Volume: 23 Page(s): 2030 - 2041
12/01/2013 Authors: Lai AY; Mav D; Shah R; Grimm SA; Phadke D; Hatzi K; Melnick A; Geigerman C; Sobol SE; Jaye DL
Using RNA-Seq, SNP-CN and Targeted Deep Sequencing To Improve The Diagnostic Paradigm In Multiple Myeloma
Volume: 122
11/15/2013 Authors: Rossi MR; Newman S; Nooka AK; Kaufman JL; Bahlis NJ; Neri P; Matulis SM; Bernal-Mizrachi L; Gupta VA; Varma A
Expression Of PD-L1 Is Required To Control Acute GvHD In Allo-HSCT Recipients
Volume: 122
11/15/2013 Authors: Hossain MS; El-Najjar VF; Jaye DL; Ahmed R; Waller EK
A Rational Approach to Karyotyping Utilization for Multiple Myeloma
Volume: 140 Page(s): 436 - 436
09/01/2013 Authors: Nasser N; Fatima N; El-Najjar V; Guarner J; Jaye D; Hill C
An Approach to Optimize FISH Test Utilization for Multiple Myeloma
Volume: 140 Page(s): 432 - 433
09/01/2013 Authors: El-Najjar V; Nasser N; Fatima N; Guarner J; Jaye D
Certification and role of local pathologists for diffuse large B-cell lymphoma (DLBCL) subtyping and eligibility determination in the phase II PYRAMID study
Volume: 31
05/20/2013 Authors: Said JW; Reeves JA; Flinn I; Tulpule A; Robles RL; Flowers C; DiBella NJ; Kolibaba KS; Venugopal P; Kolevska T
A lamprey monoclonal VLR antibody recognizes a novel plasma cell antigen
Volume: 190
05/01/2013 Authors: Yu C; Herrin B; Jaye D; Cooper M; Ehrhardt G
Examining racial differences in diffuse large B-cell lymphoma presentation and survival.
Leuk Lymphoma Volume: 54 Page(s): 268 - 276
02/01/2013 Authors: Flowers CR; Shenoy PJ; Borate U; Bumpers K; Douglas-Holland T; King N; Brawley OW; Lipscomb J; Lechowicz MJ; Sinha R
VIPhyb, an antagonist of vasoactive intestinal peptide receptor, enhances cellular antiviral immunity in murine cytomegalovirus infected mice.
PLoS One Volume: 8 Page(s): e63381
01/01/2013 Authors: Li J-M; Darlak KA; Southerland L; Hossain MS; Jaye DL; Josephson CD; Rosenthal H; Waller EK
Purification and identification of cell surface antigens using lamprey monoclonal antibodies.
J Immunol Methods Volume: 386 Page(s): 43 - 49
12/14/2012 Authors: Yu C; Ali S; St-Germain J; Liu Y; Yu X; Jaye DL; Moran MF; Cooper MD; Ehrhardt GRA
Characteristics and outcomes of diffuse large B-cell lymphoma presenting in leukaemic phase.
Br J Haematol Volume: 158 Page(s): 608 - 614
09/01/2012 Authors: Muringampurath-John D; Jaye DL; Flowers CR; Saxe D; Chen Z; Lechowicz MJ; Weisenburger DD; Bast M; Arellano ML; Bernal-Mizrachi L
Translational applications of flow cytometry in clinical practice.
J Immunol Volume: 188 Page(s): 4715 - 4719
05/15/2012 Authors: Jaye DL; Bray RA; Gebel HM; Harris WAC; Waller EK
Rituximab-hyperfractionated cyclophosphamide, vincristine, adriamycin and dexamethasone alternating with high-dose cytarabine and methotrexate for aggressive non-Hodgkin lymphoma.
Leuk Lymphoma Volume: 53 Page(s): 725 - 727
04/01/2012 Authors: Muringampurath-John D; Flowers CR; Toscano M; Zhengjia C; Kaufman JL; Arellano M; Bernal-Mizrachi L; Heffner LT; Lechowicz M-J; McLemore M
Recovery and rebound of platelet counts in mice after thrombocytopenia induced by combination bortezomib + romidepsin.
Exp Hematol Volume: 40 Page(s): 95 - 96
02/01/2012 Authors: Giver CR; Jaye DL; Waller EK; Lonial S
Racial Differences in Prognostic Biomarkers of Diffuse Large B-Cell Lymphoma
Volume: 92 Page(s): 328A - 328A
02/01/2012 Authors: Chastain EC; Fisher KE; Bumpers K; Reddy V; Fu K; Flowers CR; Jaye DL
Racial Differences in Prognostic Biomarkers of Diffuse Large B-Cell Lymphoma
Volume: 25 Page(s): 328A - 328A
02/01/2012 Authors: Chastain EC; Fisher KE; Bumpers K; Reddy V; Fu K; Flowers CR; Jaye DL
Flagellin, a TLR5 Agonist, Reduces GvHD in Allogeneic HSCT Recipients While Enhancing Anti-Viral Immunity: A Novel Therapeutic Approach
Volume: 118 Page(s): 69 - 69
11/18/2011 Authors: Hossain MS; Jaye DL; Pollack BP; Farr AB; Roback J; Gewirtz AT; Waller EK
Flagellin, a TLR5 agonist, reduces graft-versus-host disease in allogeneic hematopoietic stem cell transplantation recipients while enhancing antiviral immunity.
J Immunol Volume: 187 Page(s): 5130 - 5140
11/15/2011 Authors: Hossain MS; Jaye DL; Pollack BP; Farris AB; Tselanyane ML; David E; Roback JD; Gewirtz AT; Waller EK
Rapid recovery from panobinostat (LBH589)-induced thrombocytopenia in mice involves a rebound effect of bone marrow megakaryocytes.
Leukemia Volume: 25 Page(s): 362 - 365
02/01/2011 Authors: Giver CR; Jaye DL; Waller EK; Kaufman JL; Lonial S
Gene and Protein Isoform Expression Analysis of the BCL-6 Associated Transcriptional Corepressor MTA3 in B- lineage Cells
Volume: 91 Page(s): 323A - 323A
02/01/2011 Authors: Spencer DV; Foulks CL; Geigerman CM; Akl PS; Lai AY; Wade PA; Jaye DL; Hill CE
Gene and Protein Isoform Expression Analysis of the BCL-6 Associated Transcriptional Corepressor MTA3 in B- lineage Cells
Volume: 24 Page(s): 323A - 323A
02/01/2011 Authors: Spencer DV; Foulks CL; Geigerman CM; Akl PS; Lai AY; Wade PA; Jaye DL; Hill CE
Examining the Racial Disparities In Presentation and Treatment for Patients with Diffuse Large B-Cell Lymphoma (DLBCL).
Volume: 116 Page(s): 647 - 647
11/12/2010 Authors: Shenoy PJ; Borate U; Bumpers K; Douglas-Holland T; King N; Lechowicz MJ; Jaye DL; Donnellan W; The A; Reddy V
Use of Rituximab with CHOP Chemotherapy Appears to Overcome Racial Disparities In Survival In Black Patients with Diffuse Large B Cell Lymphoma When Compared to CHOP Chemotherapy Alone.
Volume: 116 Page(s): 650 - 650
11/19/2010 Authors: Borate U; Shenoy PJ; Donnellan W; Bumpers K; Douglas-Holland T; King N; Lechowicz MJ; The A; Jaye DL; Reddy V
DNA methylation prevents CTCF-mediated silencing of the oncogene BCL6 in B cell lymphomas.
J Exp Med Volume: 207 Page(s): 1939 - 1950
08/30/2010 Authors: Lai AY; Fatemi M; Dhasarathy A; Malone C; Sobol SE; Geigerman C; Jaye DL; Mav D; Shah R; Li L
The role of CD11c expression in the diagnosis of mantle cell lymphoma.
Am J Clin Pathol Volume: 134 Page(s): 271 - 277
08/01/2010 Authors: Kraus TS; Sillings CN; Saxe DF; Li S; Jaye DL
Activation, immune polarization, and graft-versus-leukemia activity of donor T cells are regulated by specific subsets of donor bone marrow antigen-presenting cells in allogeneic hemopoietic stem cell transplantation.
J Immunol Volume: 183 Page(s): 7799 - 7809
12/15/2009 Authors: Li J-M; Southerland LT; Lu Y; Darlak KA; Giver CR; McMillin DW; Harris WAC; Jaye DL; Waller EK
Prognostic Significance of Circulating Lymphoma Cells in Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL)
Volume: 114 Page(s): 1151 - 1152
11/20/2009 Authors: Muringampurath-John D; Flowers CR; Jabbar AA; Sinha R; Arellano M; Bernal-Mizrachi L; Kaufman JL; Jaye DL; Chen Z; Lechowicz MJ
Functional interaction of plasmacytoid dendritic cells with multiple myeloma cells: a therapeutic target.
Cancer Cell Volume: 16 Page(s): 309 - 323
10/06/2009 Authors: Chauhan D; Singh AV; Brahmandam M; Carrasco R; Bandi M; Hideshima T; Bianchi G; Podar K; Tai Y-T; Mitsiades C
Selective targeting of nanocarriers to neutrophils and monocytes.
Ann Biomed Eng Volume: 37 Page(s): 1984 - 1992
10/01/2009 Authors: Karathanasis E; Geigerman CM; Parkos CA; Chan L; Bellamkonda RV; Jaye DL
A new immunostain algorithm classifies diffuse large B-cell lymphoma into molecular subtypes with high accuracy.
Clin Cancer Res Volume: 15 Page(s): 5494 - 5502
09/01/2009 Authors: Choi WWL; Weisenburger DD; Greiner TC; Piris MA; Banham AH; Delabie J; Braziel RM; Geng H; Iqbal J; Lenz G
14-3-3zeta mediates resistance of diffuse large B cell lymphoma to an anthracycline-based chemotherapeutic regimen.
J Biol Chem Volume: 284 Page(s): 22379 - 22389
08/14/2009 Authors: Maxwell SA; Li Z; Jaya D; Ballard S; Ferrell J; Fu H
The Mi-2/NuRD complex associates with pericentromeric heterochromatin during S phase in rapidly proliferating lymphoid cells.
Chromosoma Volume: 118 Page(s): 445 - 457
08/01/2009 Authors: Helbling Chadwick L; Chadwick BP; Jaye DL; Wade PA
Neutropenia in a patient treated with ipilimumab (anti-CTLA-4 antibody).
J Immunother Volume: 32 Page(s): 322 - 324
04/01/2009 Authors: Akhtari M; Waller EK; Jaye DL; Lawson DH; Ibrahim R; Papadopoulos NE; Arellano ML
DONOR DENDRITIC CELLS INITIATE COUNTER-REGULATORY IMMUNE RESPONSES AND GVL EFFECTS IN ALLLOGENEIC BMT
Volume: 15 Page(s): 119 - 119
02/01/2009 Authors: Li J-M; Darlak KA; Lu Y; Harris W; Jaye DL; Waller EK
Mycosis Fungoides/Sezary Syndrome Staging: Potential Pitfalls in Analyzing Bone Marrow and Lymph Nodes Using Flow Cytometric and Molecular Diagnostic Methods
Volume: 89 Page(s): 256A - 256A
01/01/2009 Authors: Bradley KT; Parker SS; Jaye DL
Mycosis Fungoides/Sezary Syndrome Staging: Potential Pitfalls in Analyzing Bone Marrow and Lymph Nodes Using Flow Cytometric and Molecular Diagnostic Methods
Volume: 22 Page(s): 256A - 256A
01/01/2009 Authors: Bradley KT; Parker SS; Jaye DL
Rational identification of a novel peptide for targeting nanocarriers to 9L glioma.
J Biomed Mater Res A Volume: 87 Page(s): 728 - 738
12/01/2008 Authors: Agarwal A; Jaye DL; Giegerman CM; Bellamkonda RV
A new immunostain algorithm improves the classification of diffuse large B-cell lymphoma into prognostically significant subgroups
Volume: 88 Page(s): 250A - 250A
01/01/2008 Authors: Choi WWL; Weisenburger DD; Greiner TC; Piris MA; Banham AH; Jaye DL; Wade PA; Iqbal J; Hans CP; Fu K
CD11b-donor dendritic cells elevate donor T-Cell production of interferon-gamma and graft-versus-leukemia activity in allogeneic bone marrow transplantation
Volume: 110 Page(s): 648A - 649A
11/16/2007 Authors: Li J-M; Southerland L; Giver C; McMillion D; Harris W; Jaye DL; Waller N
Analysis of minimal residual disease (MRD) from the phase 2 multicenter study of subcutaneous (SC) alemtuzumab combined with fludarabine for treatment of relapsed/refractory B-cell chronic lymphocytic leukemia (CLL).
Volume: 110 Page(s): 915A - 915A
11/16/2007 Authors: Flowers C; Rosenthal H; Brown J; Stock W; Katzen H; Lakhanpal S; Jaye D
The BCL6-associated transcriptional co-repressor, MTA3, is selectively expressed by germinal centre B cells and lymphomas of putative germinal centre derivation.
J Pathol Volume: 213 Page(s): 106 - 115
09/01/2007 Authors: Jaye DL; Iqbal J; Fujita N; Geigerman CM; Li S; Karanam S; Fu K; Weisenburger DD; Chan WC; Moreno CS
Chronic GvHD decreases antiviral immune responses in allogeneic BMT.
Blood Volume: 109 Page(s): 4548 - 4556
05/15/2007 Authors: Hossain MS; Roback JD; Pollack BP; Jaye DL; Langston A; Waller EK
Chronic GVHD decreases anti-cmv immune responses in allogeneic BMT: Defect in T-cell homing
Volume: 13 Page(s): 126 - 126
02/01/2007 Authors: Hossain MS; Roback JD; Pollack BP; Jaye DL; Waller EK
Expression of the plasmacytoid dendritic cell marker BDCA-2 supports a spectrum of maturation among CD4+ CD56+ hematodermic neoplasms.
Mod Pathol Volume: 19 Page(s): 1555 - 1562
12/01/2006 Authors: Jaye DL; Geigerman CM; Herling M; Eastburn K; Waller EK; Jones D
Sex-determining region Y box 4 is a transforming oncogene in human prostate cancer cells.
Cancer Res Volume: 66 Page(s): 4011 - 4019
04/15/2006 Authors: Liu P; Ramachandran S; Ali Seyed M; Scharer CD; Laycock N; Dalton WB; Williams H; Karanam S; Datta MW; Jaye DL
Relapse rates in patients with AML in relation to type of transplant and CD56 positivity
Volume: 86 Page(s): 248A - 248A
01/01/2006 Authors: Taylor K; Jaye D; Graiser M; Easley K; Waller E
Relapse rates in patients with AML in relation to type of transplant and CD56 positivity
Volume: 19 Page(s): 248A - 248A
01/01/2006 Authors: Taylor K; Jaye D; Graiser M; Easley K; Waller E
Risk factors and kinetics of thrombocytopenia associated with bortezomib for relapsed, refractory multiple myeloma.
Blood Volume: 106 Page(s): 3777 - 3784
12/01/2005 Authors: Lonial S; Waller EK; Richardson PG; Jagannath S; Orlowski RZ; Giver CR; Jaye DL; Francis D; Giusti S; Torre C
Interaction of ICAM-1 with beta 2-integrin CD11c/CD18: characterization of a peptide ligand that mimics a putative binding site on domain D4 of ICAM-1.
Eur J Immunol Volume: 35 Page(s): 3610 - 3621
12/01/2005 Authors: Frick C; Odermatt A; Zen K; Mandell KJ; Edens H; Portmann R; Mazzucchelli L; Jaye DL; Parkos CA
Donor DC subsets polarize donor T-cell immune responses in allogeneic BMT.
Volume: 106 Page(s): 170A - 170A
11/16/2005 Authors: Li JM; Giver C; McMillan D; Harris W; Jaye DL; Walter N
Apolipoprotein D is down-regulated during malignant transformation of neurofibromas.
Hum Pathol Volume: 36 Page(s): 987 - 993
09/01/2005 Authors: Hunter S; Weiss S; Ou C-Y; Jaye D; Young A; Wilcox J; Arbiser JL; Monson D; Goldblum J; Nolen JD
Bortezomib-associated transient and cyclical thrombocytopenia: evidence for lack of marrow cytotoxicity.
Volume: 23 Page(s): 587S - 587S
06/01/2005 Authors: Lonial S; Waller EK; Richardson PG; Jagannath S; Orlowski RZ; Giver CR; Jaye DL; Barlogie B; Heffner LT; Anderson KC
Interaction of ICAM-1 with beta 2-integrin CD11c/CD18
Volume: 19 Page(s): A269 - A269
03/04/2005 Authors: Frick C; Odermatt A; Zen K; Mandell KJ; Edens H; Portmann R; Mazzucchelli L; Jaye DL; Parkos CA
Direct fluorochrome labeling of phage display library clones for studying binding specificities: applications in flow cytometry and fluorescence microscopy.
J Immunol Methods Volume: 295 Page(s): 119 - 127
12/01/2004 Authors: Jaye DL; Geigerman CM; Fuller RE; Akyildiz A; Parkos CA
Identification of peptide sequences that selectively bind type 2 dendritic cells and a subset of plasmacytoid dendritic cell-related acute myelogenous leukemia: Implications for immunotherapy
Volume: 27 Page(s): S6 - S7
11/01/2004 Authors: Waller E; Rosenthal H; Taylor K; Li JM; Jaye D
MTA3 and the Mi-2/NuRD complex regulate cell fate during B lymphocyte differentiation.
Cell Volume: 119 Page(s): 75 - 86
10/01/2004 Authors: Fujita N; Jaye DL; Geigerman C; Akyildiz A; Mooney MR; Boss JM; Wade PA
Evidence for a role of TLR 2 in modulation of FMLP-directed PMN transmigration by lumenal bacterial products
Volume: 126 Page(s): A120 - A121
04/01/2004 Authors: Reaves TA; Liu Y; Jaye D; Lee HK; Tobias P; Parkos C
Isolation and functional inhibitory affects of specific peptides bound to type 2 dendritic cells (DC2)
Volume: 10 Page(s): 16 - 17
02/01/2004 Authors: Rosenthal HS; Jaye DL; Cherry E; Waller EK
Allogeneic T cells treated with amotosalen prevent lethal cytomegalovirus disease without producing graft-versus-host disease following bone marrow transplantation.
J Immunol Volume: 171 Page(s): 6023 - 6031
12/01/2003 Authors: Roback JD; Hossain MS; Lezhava L; Gorechlad JW; Alexander SA; Jaye DL; Mittelstaedt S; Talib S; Hearst JE; Hillyer CD
Ex vivo fludarabine exposure inhibits graft-versus-host activity of allogeneic T cells while preserving graft-versus-leukemia effects.
Biol Blood Marrow Transplant Volume: 9 Page(s): 616 - 632
10/01/2003 Authors: Giver CR; Montes RO; Mittelstaedt S; Li J-M; Jaye DL; Lonial S; Boyer MW; Waller EK
Use of real-time polymerase chain reaction to identify cell- and tissue-type-selective peptides by phage display.
Am J Pathol Volume: 162 Page(s): 1419 - 1429
05/01/2003 Authors: Jaye DL; Nolte FS; Mazzucchelli L; Geigerman C; Akyildiz A; Parkos CA
MTA3, a Mi-2/NuRD complex subunit, regulates an invasive growth pathway in breast cancer.
Cell Volume: 113 Page(s): 207 - 219
04/18/2003 Authors: Fujita N; Jaye DL; Kajita M; Geigerman C; Moreno CS; Wade PA
Local synthesis of coagulation factor VII in prostate cancer
Volume: 17 Page(s): A1345 - A1345
03/17/2003 Authors: Wilcox JN; Jaye DL; Joseph G; Casanova JR
Writ pathway abnormalities in synovial sarcoma (SS): An immunohistochemical study of Wnt-1, beta-catenin, axin, APC, and GSK-3 beta proteins
Volume: 83 Page(s): 299A - 299A
01/01/2003 Authors: Popp AC; Jaye D; Weiss SW; Fisher C; Folpe AL
Wnt pathway abnormalities in synovial sarcoma (SS): An immunohistochemical study of Wnt-1, beta-catenin, axin, APC, and GSK-3 beta proteins
Volume: 16 Page(s): 299A - 299A
01/01/2003 Authors: Popp AC; Jaye D; Weiss SW; Fisher C; Folpe AL
Fludarabine treatment of allogeneic donor lymphocytes selects for Th2 regulatory T-cells and reduces GvHD activity in MHC mis-matched murine BMT.
Volume: 100 Page(s): 824A - 825A
11/16/2002 Authors: Giver CR; Montes RO; Mittelstaedt S; Jaye DL; Lonial S; Li JM; Boyer MW; Waller EK
Neutrophil transepithelial migration: evidence for sequential, contact-dependent signaling events and enhanced paracellular permeability independent of transjunctional migration.
J Immunol Volume: 169 Page(s): 476 - 486
07/01/2002 Authors: Edens HA; Levi BP; Jaye DL; Walsh S; Reaves TA; Turner JR; Nusrat A; Parkos CA
Differential expression between pilocytic and anaplastic astrocytomas: identification of apolipoprotein D as a marker for low-grade, non-infiltrating primary CNS neoplasms.
J Neuropathol Exp Neurol Volume: 61 Page(s): 275 - 281
03/01/2002 Authors: Hunter S; Young A; Olson J; Brat DJ; Bowers G; Wilcox JN; Jaye D; Mendrinos S; Neish A
Novel G protein-coupled responses in leukocytes elicited by a chemotactic bacteriophage displaying a cell type-selective binding peptide.
J Immunol Volume: 166 Page(s): 7250 - 7259
06/15/2001 Authors: Jaye DL; Edens HA; Mazzucchelli L; Parkos CA
Neutrophil interactions with intestinal epithelium: Transepithelial migration-independent effects of neutrophils on paracellular permeability can occur in the absence of gross alterations in intercellular junction structure
GASTROENTEROLOGY Volume: 120 Page(s): A125 - A125
04/01/2001 Authors: Edens HA; Jaye DL; Nusrat A; Parkos CA
Leukemia-specific cell surface binding peptides: Identification using phage display techniques.
AMERICAN JOURNAL OF CLINICAL PATHOLOGY Volume: 114 Page(s): 648 - 648
10/01/2000 Authors: Jaye DL; Mazzucchelli L; Parkos CA
Histologic examination of bone marrow core biopsy specimens has limited value in the diagnosis of mycobacterial and fungal infections in patients with the acquired immunodeficiency syndrome.
Ann Diagn Pathol Volume: 4 Page(s): 1 - 6
02/01/2000 Authors: Marques MB; Waites KB; Jaye DL; Kilby JM; Reddy VV
Neutrophil migration across intestinal epithelium.
Ann N Y Acad Sci Volume: 915 Page(s): 151 - 161
01/01/2000 Authors: Jaye DL; Parkos CA
An automated semiquantitative B and T cell clonality assay.
Mol Diagn Volume: 4 Page(s): 101 - 117
06/01/1999 Authors: Miller JE; Wilson SS; Jaye DL; Kronenberg M
Comparison of two rapid latex agglutination tests for detection of cryptococcal capsular polysaccharide.
Am J Clin Pathol Volume: 109 Page(s): 634 - 641
05/01/1998 Authors: Jaye DL; Waites KB; Parker B; Bragg SL; Moser SA
The yield of bone marrow biopsy and culture compared with blood culture in the evaluation of HIV-infected patients for mycobacterial and fungal infections.
Am J Med Volume: 104 Page(s): 123 - 128
02/01/1998 Authors: Kilby JM; Marques MB; Jaye DL; Tabereaux PB; Reddy VB; Waites KB
Diagnosis of opportunistic infections in AIDS patients by bone marrow examination.
MODERN PATHOLOGY Volume: 11 Page(s): 146A - 146A
01/01/1998 Authors: Marques MB; Jaye DL; Waites KB; Reddy VVB
Clinical applications of C-reactive protein in pediatrics.
Pediatr Infect Dis J Volume: 16 Page(s): 735 - 746
08/01/1997 Authors: Jaye DL; Waites KB
Gene transfer to avian embryos with a recombinant adenovirus.
Dev Biol Volume: 166 Page(s): 355 - 359
11/01/1994 Authors: Yamagata M; Jaye DL; Sanes JR
The properdin-like type I repeats of human thrombospondin contain a cell attachment site.
J Cell Biol Volume: 112 Page(s): 1031 - 1040
03/01/1991 Authors: Prater CA; Plotkin J; Jaye D; Frazier WA
Purification and characterization of an abundant cytosolic protein from human neutrophils that promotes Ca2(+)-dependent aggregation of isolated specific granules.
J Clin Invest Volume: 85 Page(s): 1065 - 1071
04/01/1990 Authors: Ernst JD; Hoye E; Blackwood RA; Jaye D

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