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Profile

Dawn Laney MS/CGC

  • Department of Human Genetics
    Associate Professor
  • (404) 778-8518
  • dawn.laney@emory.edu
  • 101 Woodruff Circle
    Suite 7130
    Atlanta, GA 30322
Head shot of Dawn Laney

Overview

Ms. Laney is a genetic counselor, associate professor, researcher, director of the Genetic Clinical Trials Center, and program leader of the Emory Lysosomal Storage Disease Center at Emory University in the Department of Human Genetics. Ms. Laney received her masters degree in medical genetics from Sarah Lawrence College in 1999. She received her certification from the American Board of Genetic Counseling in 2002. Since joining the Emory Division of Medical Genetics in 2002, Ms. Laney has been involved in the follow-up of abnormal metabolic newborn screening for the state of Georgia development, and management of a genetic infusion center, and lysosomal storage disease clinical care and research.

As well as being the Emory Lysosomal Storage Disease Center Program Lead and Emory Genetic Clinical Trials Center Director, Ms. Laney also serves on the Emory Biomedical IRB Committee and teaches Developmental Biology and Human Malformation course (HGC 725).

Ms. Laney's main clinical research interests are in the lysosomal storage diseases, particularly Fabry disease, with emphasis on elucidation of natural history, exploration of psychological disease manifestations and treatment, assisting with the transition from childhood to adulthood, clarifying disease information provision to patients/families, finding mechanisms to facilitate testing at-risk family members, and delineating disease-related reproductive issues. She is also deeply interested in genetic education and the creation of new resources for patients/families living with genetic conditions and healthcare providers.

Academic Appointment

  • Associate Professor, Human Genetics, Emory University
  • Assistant Professor, Human Genetics, Emory School of Medicine
  • Research Interviewer, Emory University Hospital
  • Genetic Counselor, Childrens Healthcare of Atlanta
  • Genetic Counselor, Emory School of Medicine

Education

Degrees

  • M.S. from Sarah Lawrence College
  • BA from Trinity College

Research

Focus

  • My clinical research interest is in the lysosomal storage diseases, particularly Fabry disease, with emphasis on elucidation of natural history, exploration of psychological disease manifestations and treatment, assisting with transition from childhood to adulthood, clarifying disease information provision to patients/families, finding mechanisms to facilitate testing at risk family members, and delineating disease related reproductive issues.

Publications

  • Benefits, limitations, and impacts of reproductive carrier screening and telehealth-based genetic counseling for individuals with an increased chance to have a child with agenetic condition.
    J Genet Couns Volume: 34 Page(s): e70002
    06/01/2025 Authors: Hardy MW; Bruder K; Rosen A; Ali N; Laney D; Moore RH; Rose E; Sun Y; Grinzaid KA
  • Health care providers' experiences with genetic testing in patients at risk for hereditary angioedema.
    J Allergy Clin Immunol Glob Volume: 4 Page(s): 100445
    05/01/2025 Authors: Laney DA; Lee TD; Druss J; O'Keefe RL; Engel P; Riedl M
  • A study to identify individuals at risk to be affected by late-onset Pompe disease who had previously been given a non-specific or tentative diagnosis for their muscle weakness (Pompe PURSUE).
    Orphanet J Rare Dis Volume: 20 Page(s): 23
    01/14/2025 Authors: Laney DA; Banks KA; Botha EG; Keever M; Long V; Foley AL
  • Patient-reported experience with Fabry disease and its management in the real-world setting: results from a double-blind, cross-sectional survey of 280 respondents.
    Orphanet J Rare Dis Volume: 19 Page(s): 153
    04/11/2024 Authors: Berry L; Walter J; Johnson J; Alton J; Powers J; Llria X; Koulinska I; McGee M; Laney D
  • Prospective characterization of early symptom onset and progression in young pediatric patients with variants in the G LA gene across 5 years: Longitudinal data from the Fabry MOPPet Study.
    Genet Med Open Volume: 2 Page(s): 101891
    01/01/2024 Authors: Laney DA; Houde MF; Foley AL; Peck DS; Atherton AM; Manwaring LP; Grange DK; Heese BA; Holida MD; Quillin AL
  • FDrisk: development of a validated risk assessment tool for Fabry disease utilizing electronic health record data.
    J Rare Dis (Berlin) Volume: 3 Page(s): 2
    01/01/2024 Authors: Lobel CJ; Laney DA; Yang J; Jacob D; Rickheim A; Ogg CZ; Clynes D; Dronen J
  • Patient-reported experiences with Fabry disease monitoring and disease burden in the real-world setting: Results from a doubleblind, cross-sectional survey
    Volume: 138 Page(s): 16 - 17
    02/01/2023 Authors: Berry L; Johnson J; Alton J; Lloria X; Koulinska I; Laney DA
  • Validation of a suspicion index to identify patients at risk for hereditary angioedema.
    J Allergy Clin Immunol Glob Volume: 2 Page(s): 76 - 78
    02/01/2023 Authors: Shams M; Laney DA; Jacob DA; Yang J; Dronen J; Logue A; Rosen A; Riedl M
  • A study to identify individuals at risk to be affected by Pompe disease who had previously been given a non-specific or tentative diagnosis for their muscle weakness (Pompe PURSUE)
    Volume: 135 Page(s): S103 - S103
    02/03/2022 Authors: Quirin KA; Botha EG; Keever M; Long V; Foley AL; Laney DA
  • Possible increased incidence of pathogenic GALC deletions in exons 11-17 causing infantile onset Krabbe disease in individuals from Ahmadabad in the Indian state of Gujarat
    Volume: 135 Page(s): S70 - S70
    02/03/2022 Authors: Laney DA; Black E; Russo RS
  • Initial symptom presentation in young pediatric patients with classic pathogenic variants in the GLA gene: Data from the Fabry MOPPet study
    Volume: 135 Page(s): S71 - S71
    02/03/2022 Authors: Laney DA; Houde MF; Foley A; Peck DS; Atherton AM; Toler TL; Manwaring L; Nimmons K; Grange DK; Kidwell C
  • Implementation of an automated prediction scoring system to identify patients at possible increased risk for Hereditary Angioedema
    Volume: 149 Page(s): AB42 - AB42
    02/01/2022 Authors: Laney D; Shams M; Jacob D; Yang JJ; Dronen J; Logue A; Rosen A; Riedl M
  • Attention Deficits and ADHD Symptoms in Adults with Fabry Disease-A Pilot Investigation.
    J Clin Med Volume: 10
    07/29/2021 Authors: Ali N; Caceres A; Hall EW; Laney D
  • KrabbeConnect patient journey map
    Volume: 132 Page(s): S92 - S92
    02/01/2021 Authors: Rugari A; Ogg C; Laney D; Pike-Langenfeld S
  • Fabry disease and COVID-19: International expert recommendations for management based on real-world experience
    Volume: 132 Page(s): S62 - S62
    02/01/2021 Authors: Laney DA; Germain DP; Oliveira JP; Burlina AP; Cabrera GH; Hong G-R; Hopkin RJ; Niu D-M; Thomas M; Trimarchi H
  • Fabry disease and COVID-19: international expert recommendations for management based on real-world experience.
    Clin Kidney J Volume: 13 Page(s): 913 - 925
    12/01/2020 Authors: Laney DA; Germain DP; Oliveira JP; Burlina AP; Cabrera GH; Hong G-R; Hopkin RJ; Niu D-M; Thomas M; Trimarchi H
  • Fabry Disease practice resource: Focused revision.
    J Genet Couns Volume: 29 Page(s): 715 - 717
    10/01/2020 Authors: Henderson N; Berry L; Laney DA
  • Disease burden and treatment considerations in Krabbe disease: The caregiver perspective
    Volume: 129 Page(s): S129 - S129
    02/01/2020 Authors: Pike-Langenfeld SL; Laney D; Rugari A; Ogg C
  • Facial phenotyping in Fabry disease using Face2Gene
    Volume: 129 Page(s): S109 - S109
    02/01/2020 Authors: Mehr L; Simmons M; Laney D
  • Use of flotation-REST (restricted environmental stimulation technique) therapy in treatment of Fabry disease related pain
    Volume: 129 Page(s): S95 - S95
    02/01/2020 Authors: Laney DA; Westhoff C
  • Longitudinal change in the urinary biomarkers of young pediatric patients with pathogenic variants in the GIA gene: Data from the MOPPet study
    Volume: 129 Page(s): S94 - S95
    02/01/2020 Authors: Laney DA; Holida M; Simmons MF; Nimmons K; Atherton AM; Vengoechea E; Hall EW; Kidwell CF; Peck D; Manwaring L
  • Key signs and symptoms associated with GLA variant detection in relatives of an individual with a known GLA variant
    Volume: 129 Page(s): S148 - S148
    02/01/2020 Authors: Simmons MF; Laney DA; Urquhart OR; Pass S; Mulle JG
  • Determining the disease-specific knowledge gaps in patients, family members, and caregivers living with lysosomal diseases
    Volume: 126 Page(s): S95 - S95
    02/01/2019 Authors: Loucopoulos G; Laney D; Simmons M; Babu D; Garber K; Bellcross C
  • Interfamily variability in patients with classical Fabry disease
    Volume: 126 Page(s): S90 - S91
    02/01/2019 Authors: Laney DA
  • Phenotypic characteristics of the p.Asn215Ser (p.N215S) GLA mutation in male and female patients with Fabry disease: A multicenter Fabry Registry study.
    Mol Genet Genomic Med Volume: 6 Page(s): 492 - 503
    04/12/2018 Authors: Germain DP; Brand E; Burlina A; Cecchi F; Garman SC; Kempf J; Laney DA; Linhart A; Mardi L; Nicholls K
  • Fabry disease revisited: Management and treatment recommendations for adult patients.
    Mol Genet Metab Volume: 123 Page(s): 416 - 427
    04/01/2018 Authors: Ortiz A; Germain DP; Desnick RJ; Politei J; Mauer M; Burlina A; Eng C; Hopkin RJ; Laney D; Linhart A
  • The future is now: Technology's impact on the practice of genetic counseling.
    Am J Med Genet C Semin Med Genet Volume: 178 Page(s): 15 - 23
    03/01/2018 Authors: Gordon ES; Babu D; Laney DA
  • ThinkGenetic: A pilot project to create an educational website/application providing increased access to information on accurate natural history, diagnosis, and treatment information with treatable genetic disorders to healthcare providers
    Volume: 123 Page(s): S82 - S82
    02/01/2018 Authors: Laney DA; Simmons M
  • Identification of a HEXB variant of unknown clinical significance in a family with Sandhoff disease
    Volume: 123 Page(s): S131 - S132
    02/01/2018 Authors: Simmons MF; Laney D
  • Planning, implementation, and initial results of newborn screening for Pompe disease and MPS I in Georgia
    Volume: 123 Page(s): S47 - S47
    02/01/2018 Authors: Foley A; Cagle S; Hagar A; Hall P; Laney D; Russo RS; Wittenauer A; Wilcox WR
  • A prospective, multicenter pilot study of Fabry disease clinical and biochemical findings in young pediatric patients: The MOPPet baseline data
    Volume: 123 Page(s): S82 - S82
    02/01/2018 Authors: Laney DA; Simmons MF; Foley AL; Smith ED; Hall EW; Clark AK; Peck DS; Atherton AM; Toler TL; Manwaring L
  • The Psychosocial Impact of Carrying a Debated Variant in the GLA Gene.
    J Genet Couns Volume: 27 Page(s): 217 - 224
    02/01/2018 Authors: Macklin S; Laney D; Lisi E; Atherton A; Smith E
  • Treatment of Depression in Adults with Fabry Disease.
    JIMD Rep Volume: 38 Page(s): 13 - 21
    01/01/2018 Authors: Ali N; Gillespie S; Laney D
  • Sudden, pronounced height increase for adolescent and young adult males with Fabry disease
    Volume: 120 Page(s): S80 - S80
    01/01/2017 Authors: Laney DA
  • ThinkGenetic: identification of misinformation and educational gaps using an innovative and interactive website
    Volume: 120 Page(s): S123 - S123
    01/01/2017 Authors: Simmons MF; Laney DA
  • The phenotypic characteristics of the p.N215S Fabry disease genotype in male and female patients: a multi-center Fabry Registry study
    Volume: 120 Page(s): S51 - S52
    01/01/2017 Authors: Germain DP; Brand E; Cecchi F; Kempf J; Laney DA; Linhart A; Marodi L; Nicholls K; Pieruzzi F; Shankar SP
  • Preliminary validation of telecounseling for depression in patients with Fabry disease
    Volume: 120 Page(s): S19 - S20
    01/01/2017 Authors: Ali N; Gillespie S; Laney D
  • Identification of lysosomal acid lipase (LAL) deficiency patients using key existing clinical data points focused on BMI, type 2 hyperlipidemia, and/or fatty liver disease
    Volume: 120 Page(s): S86 - S86
    01/01/2017 Authors: Long V; Laney D; Shankar S; Li H
  • The Impact of Fabry Disease on Reproductive Fitness.
    Volume: 37 Page(s): 85 - 97
    01/01/2017 Authors: Laney DA; Clarke V; Foley A; Hall EW; Gillespie SE; Holida M; Simmons M; Wadley A
  • Patients' perspectives on newborn screening for later-onset lysosomal storage diseases.
    Mol Genet Metab Volume: 119 Page(s): 109 - 114
    09/01/2016 Authors: Lisi EC; Gillespie S; Laney D; Ali N
  • Machine learning based analytics of micro-MRI trabecular bone microarchitecture and texture in type 1 Gaucher disease.
    J Biomech Volume: 49 Page(s): 1961 - 1968
    06/14/2016 Authors: Sharma GB; Robertson DD; Laney DA; Gambello MJ; Terk M
  • The impact of treatment availability on reproduction in Fabry disease
    Volume: 117 Page(s): S91 - S91
    02/01/2016 Authors: Pass S; Laney D
  • Examining the psychosocial impact of carrying the p.A143T variant in the GLA gene
    Volume: 117 Page(s): S76 - S76
    02/01/2016 Authors: Macklin S; Laney D; Atherton A; Peck D; Manwaring L; Christensen K
  • Barriers in communication and available resources to facilitate conversation about infertility with girls diagnosed with Turner syndrome.
    J Pediatr Endocrinol Metab Volume: 29 Page(s): 185 - 191
    02/01/2016 Authors: King JE; Plamondon J; Counts D; Laney D; Dixon SD
  • Eye findings in Fabry disease and correlation with disease severity
    Volume: 117 Page(s): S104 - S105
    02/01/2016 Authors: Shankar SP; Bradley A; Gillespie S; Stelton C; Kharod-Dholakia B; Laney D; Yan J
  • Natural history of Fabry disease in male and female patients with the N215S genotype
    Volume: 117 Page(s): S48 - S49
    02/01/2016 Authors: Germain DP; Brand E; Cecchi F; Kempf J; Laney DA; Linhart A; Marodi L; Shankar SP; Waldek S; Wanner C
  • The impact of Fabry disease on reproductive fitness
    Volume: 117 Page(s): S70 - S70
    02/01/2016 Authors: Laney DA; Clark V; Holida M
  • Anti-proteinuric therapy and Fabry nephropathy; factors associated with preserved kidney function during agalsidase-beta therapy
    Volume: 117 Page(s): S120 - S120
    02/01/2016 Authors: Warnock DG; Thomas CP; Vujkovac B; Campbell RC; Charrow J; Laney DA; Jackson LL; Wilcox WR; Wanner C
  • The management and treatment of children with Fabry disease: A United States-based perspective.
    Mol Genet Metab Volume: 117 Page(s): 104 - 113
    02/01/2016 Authors: Hopkin RJ; Jefferies JL; Laney DA; Lawson VH; Mauer M; Taylor MR; Wilcox WR; Fabry Pediatric Expert Panel
  • Antiproteinuric therapy and Fabry nephropathy: factors associated with preserved kidney function during agalsidase-beta therapy.
    J Med Genet Volume: 52 Page(s): 860 - 866
    12/01/2015 Authors: Warnock DG; Thomas CP; Vujkovac B; Campbell RC; Charrow J; Laney DA; Jackson LL; Wilcox WR; Wanner C
  • Fabry disease in infancy and early childhood: a systematic literature review.
    Genet Med Volume: 17 Page(s): 323 - 330
    05/01/2015 Authors: Laney DA; Peck DS; Atherton AM; Manwaring LP; Christensen KM; Shankar SP; Grange DK; Wilcox WR; Hopkin RJ
  • Trabeculae bone structure analysis in individuals affected by type 1 Gaucher disease using micro magnetic resonance imaging
    Volume: 114 Page(s): S74 - S74
    02/01/2015 Authors: Long V; Sharma GB; Robertson DD; Xing M; Harmouche E; Podgorsky Y; Laney DA; Gambello MJ; Lisi E; Chamieh J
  • Comparison of clinical practice guidelines and actual clinical practice in Fabry disease diagnosis
    Volume: 114 Page(s): S68 - S68
    02/01/2015 Authors: Laney DA; White AL; Holida M; Clarke V; Lipinski S; Berry L; May K; Long K
  • A Retrospective Survey Studying the Impact of Fabry Disease on Pregnancy.
    Volume: 21 Page(s): 57 - 63
    01/01/2015 Authors: Holmes A; Laney D
  • Cognitive function in adults aging with fabry disease: a case-control feasibility study using telephone-based assessments.
    JIMD Rep Volume: 18 Page(s): 41 - 50
    01/01/2015 Authors: Wadley VG; McClure LA; Warnock DG; Lassen-Greene CL; Hopkin RJ; Laney DA; Clarke VM; Kurella Tamura M; Howard G; Sims K
  • A Retrospective Survey Studying the Impact of Fabry Disease on Pregnancy
    JIMD Reports Volume: 21 Page(s): 57 - 63
    01/01/2015 Authors: Laney DA; Holmes A
  • Climbing the branches of a family tree: diagnosis of fragile X syndrome.
    J Pediatr Volume: 164 Page(s): 1292 - 1295
    06/01/2014 Authors: Visootsak J; Hipp H; Clark H; Berry-Kravis E; Anderson T; Laney D
  • Fabry disease practice guidelines: recommendations of the National Society of Genetic Counselors.
    J Genet Couns Volume: 22 Page(s): 555 - 564
    10/01/2013 Authors: Laney DA; Bennett RL; Clarke V; Fox A; Hopkin RJ; Johnson J; O'Rourke E; Sims K; Walter G
  • An open-label, switchover trial to assess the safety and efficacy of Fabrazyme in patients with Fabry disease treated with Replagal enzyme replacement therapy
    Volume: 108 Page(s): S78 - S79
    02/01/2013 Authors: Richards S; Laney D; Pervaiz MA; Shankar S
  • Beyond brochures: Evaluating resources about lysosomal storage diseases for children and preteens
    Volume: 108 Page(s): S58 - S58
    02/01/2013 Authors: Laney D
  • The impact of Fabry on pregnancy (IFOP)
    Volume: 108 Page(s): S48 - S48
    02/01/2013 Authors: Holmes A; Laney D; Shankar S
  • Depression in Patients with Fabry Disease: The Benefits of Telephone-Administered Versus Face-to-Face Psychological Counseling
    Volume: 105 Page(s): S16 - S16
    02/01/2012 Authors: Ali N; Laney D; Fernhoff P; Shankar S
  • Dyslipidemia and Fabry Disease
    Volume: 105 Page(s): S43 - S43
    02/01/2012 Authors: Laney D; Fernhoff P; Hill C; Yupari ME; Shankar S; Pervaiz MA; Thompson R
  • Social-adaptive and psychological functioning of patients affected by Fabry disease.
    J Inherit Metab Dis Volume: 33 Suppl 3 Page(s): S73 - S81
    12/01/2010 Authors: Laney DA; Gruskin DJ; Fernhoff PM; Cubells JF; Ousley OY; Hipp H; Mehta AJ
  • PROTEIN QUANTIFICATION OF HUMAN ACID ALPHA-GLUCOSIDASE IN LEUKOCYTES BY MRM-INITIATED DETECTION AND SEQUENCING (MIDAS) USING LC-MSMS/TRAP 5500
    Volume: 99 Page(s): 237 - 237
    03/01/2010 Authors: Xia B; Li X; Botha EG; Na L; Laney D; He M
  • Spontaneous pneumothorax in a young man affected by Fabry disease
    Volume: 99 Page(s): S24 - S24
    02/01/2010 Authors: Laney D; Fernhoff P; Abramowsky C; Roman-Rodriguez J; Hennigar R
  • Fabry nephropathy (FN) and the agalsidase beta and ARBs and ACE inhibitor treatment (FAACET) study: Determinants of proteinuria during the titration phase
    Volume: 99 Page(s): S38 - S38
    02/01/2010 Authors: Warnock DG; Jackson L; Thomas C; Phillips E; Guasch T; Laney DA; Charrow J; Widera S
  • Environmental and genetic explorations into discordant disease expression in a pair of female monozygotic twins affected by Fabry disease
    Volume: 99 Page(s): S24 - S24
    02/01/2010 Authors: Laney D; Fernhoff P; Hedge M; Alexander C
  • FABRY NEPHROPATHY AND THE FABRAZYME AND ARBS AND ACE INHIBITOR TREATMENT (FAACET) STUDY: DETERMINANTS OF PROTEINURIA DURING THE TITRATION PHASE
    Volume: 32 Page(s): S115 - S115
    01/01/2010 Authors: Campbell RC; Jackson L; Thomas CP; Birrer E; Guasch T; Laney DA; Charrow J; Widera S; Warnock DG
  • FABRY NEPHROPATHY AND THE FABRAZYME AND ARBS AND ACE INHIBITOR TREATMENT (FAACET) STUDY: BASELINE EVALUATION AND REDUCTION OF PROTEINURIA TO 0.5 GRAMS/DAY
    Volume: 32 Page(s): S114 - S115
    01/01/2010 Authors: Warnock DG; Jackson L; Thomas CP; Birrer E; Guasch T; Laney DA; Charrow J; Widera S
  • Severe hydrocephalus in mucolipidosis type II: A case report
    Volume: 96 Page(s): S18 - S18
    02/01/2009 Authors: Clark H; Laney D; Fernhoff P
  • Creating genetics-based infusion centers: a case study of two models.
    Genet Med Volume: 10 Page(s): 626 - 632
    08/01/2008 Authors: Laney DJ; White AL; Rhead WJ; Fernhoff P
  • Diagnosis of Fabry disease via analysis of family history.
    J Genet Couns Volume: 17 Page(s): 79 - 83
    02/01/2008 Authors: Laney DA; Fernhoff PM
  • Reproductive fitness in individuals affected by Fabry disease
    Volume: 93 Page(s): S28 - S28
    02/01/2008 Authors: Laney D; Gruskin D; Mehta A
  • The incidence of depression and anxiety is increased in patients affected by Fabry disease
    Volume: 92 Page(s): S25 - S26
    12/01/2007 Authors: Gruskin D; Laney D; Cubells J
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