David Smith PhD
Academic Appointment
- Technical Director, The National Center for Functional Glycomics, Emory University School of Medicine
- Director, The Emory University Glycomics Center, Emory University School of Medicine
- Director, Department of Biochemistry, Emory University School of Medicine
- Professor of Biochemistry, Department of Biochemistry, Emory University School of Medicine
Education
Degrees
- PhD from The University of Texas Graduate School of Biomedical Sciences at Houston
- BS from Texas Lutheran University
- M.S. from The University of Texas Graduate School of Biomedical Sciences at Houston
Research
Focus
- My research interests are structure, function, and biosynthesis of glycoconjugates emphasizing protein-carbohydrate interactions. As Director of the Protein-Carbohydrate Interaction Core (H), I collaborate with investigators from all over the world on the specificity of Glycan Binding Proteins, including animal and plant lectins and antibodies, as well as viruses and other microorganisms.
Publications
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Serum glycomic profile as a predictive biomarker of recurrence in patients with differentiated thyroid cancer.
Cancer Med Volume: 12 Page(s): 6768 - 6777
03/01/2023 Authors: Kudelka MR; Lasanajak Y; Smith DF; Song X; Hossain MS; Owonikoko TK -
A Useful Guide to Lectin Binding: Machine-Learning Directed Annotation of 57 Unique Lectin Specificities.
ACS Chem Biol Volume: 17 Page(s): 2993 - 3012
11/18/2022 Authors: Bojar D; Meche L; Meng G; Eng W; Smith DF; Cummings RD; Mahal LK -
Morphology of Biomaterials Affect O-Glycosylation of HUVECs.
J Funct Biomater Volume: 13
11/11/2022 Authors: Hu X; Sheng J; Guan G; Ju T; Smith DF; Wang L -
Novel fold of rotavirus glycan-binding domain predicted by AlphaFold2 and determined by X-ray crystallography.
Commun Biol Volume: 5 Page(s): 419
05/05/2022 Authors: Hu L; Salmen W; Sankaran B; Lasanajak Y; Smith DF; Crawford SE; Estes MK; Prasad BVV -
Cellular O-Glycome Reporter/Amplification (CORA): Analytical and Preparative Tools to Study Mucin-Type O-Glycans of Living Cells.
Curr Protoc Volume: 1 Page(s): e142
06/01/2021 Authors: Kudelka MR; Li Z; Chernova TA; Smith DF; Song X; Cummings RD; Ju T -
Structural analysis of carbohydrate binding by the macrophage mannose receptor CD206.
J Biol Chem Volume: 296 Page(s): 100368
01/01/2021 Authors: Feinberg H; Jgouzo SAF; Lasanajak Y; Smith DF; Drickamer K; Weis WI; Taylor ME -
Erratum to: Identification of Tn antigen O-GalNAc-expressing glycoproteins in human carcinomas using novel anti-Tn recombinant antibodies.
Glycobiology Volume: 30 Page(s): 1015
12/09/2020 Authors: Matsumoto Y; Kudelka MR; Hanes MS; Lehoux S; Dutta S; Jones MB; Stackhouse KA; Cervoni GE; Heimburg-Molinaro J; Smith DF -
Amplification and Preparation of Cellular O-Glycomes for Functional Glycomics.
Anal Chem Volume: 92 Page(s): 10390 - 10401
08/04/2020 Authors: Li Z; Zhang Q; Ashline D; Zhu Y; Lasanajak Y; Chernova T; Reinhold V; Cummings RD; Wang PG; Ju T -
O-Benzylhydroxylamine (BHA) as a Cleavable Tag for Isolation and Purification of Reducing Glycans.
SLAS Technol Volume: 25 Page(s): 388 - 396
08/01/2020 Authors: Zhang Y; Zhu Y; Lasanajak Y; Smith DF; Song X -
Structural Characterization of Cuta- and Tusavirus: Insight into Protoparvoviruses Capsid Morphology.
Viruses Volume: 12
06/17/2020 Authors: Mietzsch M; McKenna R; Visnen E; Yu JC; Ilyas M; Hull JA; Kurian J; Smith JK; Chipman P; Lasanajak Y -
Influenza D virus diverges from its related influenza C virus in the recognition of 9-O-acetylated N-acetyl- or N-glycolyl-neuraminic acid-containing glycan receptors.
Virology Volume: 545 Page(s): 16 - 23
06/01/2020 Authors: Liu R; Sreenivasan C; Yu H; Sheng Z; Newkirk SJ; An W; Smith DF; Chen X; Wang D; Li F -
Identification of Tn antigen O-GalNAc-expressing glycoproteins in human carcinomas using novel anti-Tn recombinant antibodies.
Glycobiology Volume: 30 Page(s): 282 - 300
04/20/2020 Authors: Matsumoto Y; Kudelka MR; Hanes MS; Lehoux S; Dutta S; Jones MB; Stackhouse KA; Cervoni GE; Heimburg-Molinaro J; Smith DF -
Enhanced Pro-apoptotic Effects of Fe(II)-Modified IVIG on Human Neutrophils.
Front Immunol Volume: 11 Page(s): 973
01/01/2020 Authors: Graeter S; Schneider C; Verschoor D; von Dniken S; Seibold F; Yawalkar N; Villiger P; Dimitrov JD; Smith DF; Cummings RD -
Limited Neonatal Carbohydrate-Specific Antibody Repertoire Consecutive to Partial Prenatal Transfer of Maternal Antibodies.
Front Immunol Volume: 11 Page(s): 573629
01/01/2020 Authors: Kappler K; Restin T; Lasanajak Y; Smith DF; Bassler D; Hennet T -
Increased Antibody Response to Fucosylated Oligosaccharides and Fucose-Carrying Bacteroides Species in Crohn's Disease.
Front Microbiol Volume: 11 Page(s): 1553
01/01/2020 Authors: Kappler K; Lasanajak Y; Smith DF; Opitz L; Hennet T -
The architecture of the IgG anti-carbohydrate repertoire in primary antibody deficiencies.
Volume: 134 Page(s): 1941 - 1950
11/28/2019 Authors: Jandus P; Boligan KF; Smith DF; de Graauw E; Grimbacher B; Jandus C; Abdelhafez MM; Despont A; Bovin N; Simon D -
Synthesis and Characterization of Versatile O-Glycan Precursors for Cellular O-Glycomics.
ACS Synth Biol Volume: 8 Page(s): 2507 - 2513
11/15/2019 Authors: Zhang Q; Li Z; Chernova T; Saikam V; Cummings R; Song X; Ju T; Smith DF; Wang PG -
CD23 is a glycan-binding receptor in some mammalian species.
J Biol Chem Volume: 294 Page(s): 14845 - 14859
10/11/2019 Authors: Jgouzo SAF; Feinberg H; Morrison AG; Holder A; May A; Huang Z; Jiang L; Lasanajak Y; Smith DF; Werling D -
Next-Generation Glycan Microarray Enabled by DNA-Coded Glycan Library and Next-Generation Sequencing Technology.
Anal Chem Volume: 91 Page(s): 9221 - 9228
07/16/2019 Authors: Yan M; Zhu Y; Liu X; Lasanajak Y; Xiong J; Lu J; Lin X; Ashline D; Reinhold V; Smith DF -
Absence of a human ortholog of rodent Kupffer cell galactose-binding receptor encoded by the CLEC4f gene.
Glycobiology Volume: 29 Page(s): 332 - 345
04/01/2019 Authors: Taylor ME; Snelling T; Smith DF; Drickamer K -
History and future of shotgun glycomics.
Biochem Soc Trans Volume: 47 Page(s): 1 - 11
02/28/2019 Authors: Smith DF; Cummings RD; Song X -
Identification of a secondary binding site in human macrophage galactose-type lectin by microarray studies: Implications for the molecular recognition of its ligands.
J Biol Chem Volume: 294 Page(s): 1300 - 1311
01/25/2019 Authors: Marcelo F; Supekar N; Corzana F; van der Horst JC; Vuist IM; Live D; Boons G-JPH; Smith DF; van Vliet SJ -
A Well-Characterized Human Chimeric Anti-Tn Monoclonal Antibody as a Tumor Diagnostic Biomarker
Volume: 28 Page(s): 1049 - 1050
12/01/2018 Authors: Matsumoto Y; Kudelka MR; Hanes MS; Lehoux S; Heimburg-Molinaro J; Jones MB; Dutta S; Smith DF; Ju T; Cummings RD -
Preparation of an O-glycan Library from Porcine Stomach Mucin by Oxidative Release of Natural Glycans (ORNG)
Volume: 28 Page(s): 1082 - 1082
12/01/2018 Authors: Zhang S; Lasanajak Y; Zhu Y; Liu X; Bowen TJ; Smith DF; Song X -
Development of Preparative Cora for Amplification and Preparation of Cellular O-Glycans
Volume: 28 Page(s): 1074 - 1074
12/01/2018 Authors: Li Z; Zhang Q; Wang PG; Song X; Cummings RD; Ju T; Smith DF -
Anthranilic Acid as a Versatile Fluorescent Tag and Linker for Gycan Bioconjugation and Microarrary Preparation
Volume: 28 Page(s): 1087 - 1087
12/01/2018 Authors: Zhu Y; Liu X; Zhang Y; Lasanajak Y; Smith DF; Song X -
Development of Anti-Glycan VLRB Libraries from Immunized Lampreys
Volume: 28 Page(s): 1090 - 1090
12/01/2018 Authors: McKitrick TR; Rosenberg C; Heimburg-Molinaro J; Rivers N; Smith D; Cooper M; Herrin B; Cummings RD -
Next Generation Glycan Microarray Enabled by Next Generation Sequencing
Volume: 28 Page(s): 1067 - 1068
12/01/2018 Authors: Yan M; Lasanajak Y; Smith DF; Song X -
Large Scale N-glycan Preparation from Soy Proteins by Oxidative Release of Natural Glycans (ORNG)
Volume: 28 Page(s): 1086 - 1087
12/01/2018 Authors: Zhu Y; Lasanajak Y; Smith DF; Song X -
Development of a novel yeast cell-based system for studying Core 1-beta 3Galactosyltransferase and its Molecular Chaperone Cosmc
Volume: 28 Page(s): 1088 - 1088
12/01/2018 Authors: Chernova TA; Wang Q; Smith DF; Ju T -
Identification of Human Alloantibodies Using Non-Human Gene Modified RBCs as a "Blank Canvas"
Volume: 58 Page(s): 50A - 50A
10/01/2018 Authors: Zimring JC; Er LS; Kapp L; Aye T; Armour R; Smith D; Lasanajak Y; AuBuchon J; Wu Y -
Large scale preparation of high mannose and paucimannose N-glycans from soybean proteins by oxidative release of natural glycans (ORNG).
Carbohydr Res Volume: 464 Page(s): 19 - 27
07/15/2018 Authors: Zhu Y; Yan M; Lasanajak Y; Smith DF; Song X -
Glycan recognition in globally dominant human rotaviruses.
Nat Commun Volume: 9 Page(s): 2631
07/06/2018 Authors: Hu L; Sankaran B; Laucirica DR; Patil K; Salmen W; Ferreon ACM; Tsoi PS; Lasanajak Y; Smith DF; Ramani S -
A comprehensive Caenorhabditis elegans N-glycan shotgun array.
Glycobiology Volume: 28 Page(s): 223 - 232
04/01/2018 Authors: Jankowska E; Parsons LM; Song X; Smith DF; Cummings RD; Cipollo JF -
Amplification and Preparation of Cellular O-glycans using Cellular O-glycome Reporter/Amplification (CORA)
Volume: 27 Page(s): 1212 - 1213
12/01/2017 Authors: Li Z; Zhang Q; Chernova T; Wang G; Song X; Smith DF; Richard CD; Ju T -
Quantitative O-Glycomics: metabolic Stable Isotopic Labeling of O-glycomes of cultured Cells (SILOC)
Volume: 27 Page(s): 1214 - 1214
12/01/2017 Authors: Chernova TA; Li Z; Jiang Y; Wang Q; Smith DF; Ju T -
A Yeast Model to Define the Molecular Interactions between Core 1 b3GalT and its Molecular Chaperone Cosmc
Volume: 27 Page(s): 1213 - 1213
12/01/2017 Authors: Chernova TA; Wang Q; Jiang Y; Smith DF; Ju T -
A Well-Characterized Human Chimeric Anti-Tn Monoclonal Antibody with Cytotoxic Potential
Volume: 27 Page(s): 1224 - 1225
12/01/2017 Authors: Matsumoto Y; Kudelka MR; Hanes MS; Lehoux S; Heimburg-Molinaro J; Smith DF; Ju T; Cummings RD -
Expression of the Tn Tumor Antigen in Carcinomas Is Caused by Mislocalization of Cosmc/T-synthase due to Dysregulation of MAPK Pathway
Volume: 27 Page(s): 1240 - 1240
12/01/2017 Authors: Jiang Y; Kotian S; Arthur C; Stowell S; Smith DF; An G; Ju T -
Mining High-Complexity Motifs in Glycans: A New Language To Uncover the Fine Specificities of Lectins and Glycosidases.
Anal Chem Volume: 89 Page(s): 12342 - 12350
11/21/2017 Authors: Klamer Z; Staal B; Prudden AR; Liu L; Smith DF; Boons G-J; Haab B -
Pathogenicity and transmission of a swine influenza A(H6N6) virus.
Emerg Microbes Infect Volume: 6 Page(s): e17
04/12/2017 Authors: Sun H; Kaplan BS; Guan M; Zhang G; Ye J; Long L-P; Blackmon S; Yang C-K; Chiang M-J; Xie H -
The minimum information required for a glycomics experiment (MIRAGE) project: improving the standards for reporting glycan microarray-based data.
Glycobiology Volume: 27 Page(s): 280 - 284
04/01/2017 Authors: Liu Y; McBride R; Stoll M; Palma AS; Silva L; Agravat S; Aoki-Kinoshita KF; Campbell MP; Costello CE; Dell A -
Identification of the binding roles of terminal and internal glycan epitopes using enzymatically synthesized N-glycans containing tandem epitopes
Volume: 26 Page(s): 1490 - 1490
12/01/2016 Authors: Guan W; Wu Z; Liu Y; Ma C; Li L; Bai J; Byrd-Leotis L; Lasanajak Y; Guo Y; Wen L -
Identification of influenza A virus receptors found in natural tissue using shotgun glycomics approach
Volume: 26 Page(s): 1401 - 1401
12/01/2016 Authors: Byrd-Leotis LA; Liu R; Bradley KC; Lasanajak Y; Cummings SF; Song X; Heimburg-Molinaro J; Galloway SE; Culhane MR; Smith DF -
Developing Smart Anti-Glycan Reagents Using an Ancient Immune System
Volume: 26 Page(s): 1464 - 1465
12/01/2016 Authors: McKitrick TR; Rosenberg CS; Heimburg-Molinaro J; Smith DF; Herrin BR; Cooper MD; Cummings RD -
Human Intelectin-1, a member of the X-type lectin family, binds specific microbial glycans
Volume: 26 Page(s): 1490 - 1491
12/01/2016 Authors: Viola J; Lee JK; McBride R; Smith D; Cummings R; Paulson J; Moremen K; Pierce M -
Identification of the binding roles of terminal and internal glycan epitopes using enzymatically synthesized N-glycans containing tandem epitopes.
Org Biomol Chem Volume: 14 Page(s): 11106 - 11116
11/29/2016 Authors: Wu Z; Liu Y; Ma C; Li L; Bai J; Byrd-Leotis L; Lasanajak Y; Guo Y; Wen L; Zhu H -
The minimum information required for a glycomics experiment (MIRAGE) project: sample preparation guidelines for reliable reporting of glycomics datasets.
Glycobiology Volume: 26 Page(s): 907 - 910
09/01/2016 Authors: Struwe WB; Agravat S; Aoki-Kinoshita KF; Campbell MP; Costello CE; Dell A; Ten Feizi; Haslam SM; Karlsson NG; Khoo K-H -
Galectins are human milk glycan receptors.
Glycobiology Volume: 26 Page(s): 655 - 669
06/01/2016 Authors: Noll AJ; Gourdine J-P; Yu Y; Lasanajak Y; Smith DF; Cummings RD -
Oxidative release of natural glycans for functional glycomics.
Nat Methods Volume: 13 Page(s): 528 - 534
06/01/2016 Authors: Song X; Ju H; Lasanajak Y; Kudelka MR; Smith DF; Cummings RD -
Computational approaches to define a human milk metaglycome.
Bioinformatics Volume: 32 Page(s): 1471 - 1478
05/15/2016 Authors: Agravat SB; Song X; Rojsajjakul T; Cummings RD; Smith DF -
Human DC-SIGN binds specific human milk glycans.
Biochem J Volume: 473 Page(s): 1343 - 1353
05/15/2016 Authors: Noll AJ; Yu Y; Lasanajak Y; Duska-McEwen G; Buck RH; Smith DF; Cummings RD -
Identification of Antigenic Glycans from Schistosoma mansoni by Using a Shotgun Egg Glycan Microarray.
Infect Immun Volume: 84 Page(s): 1371 - 1386
05/01/2016 Authors: Mickum ML; Prasanphanich NS; Song X; Dorabawila N; Mandalasi M; Lasanajak Y; Luyai A; Secor WE; Wilkins PP; Van Die I -
Single-chain antibody-fragment M6P-1 possesses a mannose 6-phosphate monosaccharide-specific binding pocket that distinguishes N-glycan phosphorylation in a branch-specific manner.
Glycobiology Volume: 26 Page(s): 181 - 192
02/01/2016 Authors: Blackler RJ; Evans DW; Smith DF; Cummings RD; Brooks CL; Braulke T; Liu X; Evans SV; Mller-Loennies S -
Structural basis of unique glycan recognition in neonate-specific rotaviruses
Volume: 25 Page(s): 1264 - 1265
11/01/2015 Authors: Hu L; Ramani S; Czako R; Sankaran B; Yu Y; Smith DF; Cummings RD; Estes MK; Prasad BVV -
Glycan microarrays of fluorescently-tagged natural glycans.
Glycoconj J Volume: 32 Page(s): 465 - 473
10/01/2015 Authors: Song X; Heimburg-Molinaro J; Smith DF; Cummings RD -
Structural basis of glycan specificity in neonate-specific bovine-human reassortant rotavirus.
Nat Commun Volume: 6 Page(s): 8346
09/30/2015 Authors: Hu L; Ramani S; Czako R; Sankaran B; Yu Y; Smith DF; Cummings RD; Estes MK; Venkataram Prasad BV -
Recognition of microbial glycans by human intelectin-1.
Nat Struct Mol Biol Volume: 22 Page(s): 603 - 610
08/01/2015 Authors: Wesener DA; Wangkanont K; McBride R; Song X; Kraft MB; Hodges HL; Zarling LC; Splain RA; Smith DF; Cummings RD -
Upregulation of glycans containing 3' fucose in a subset of pancreatic cancers uncovered using fusion-tagged lectins.
J Proteome Res Volume: 14 Page(s): 2594 - 2605
06/05/2015 Authors: Singh S; Pal K; Yadav J; Tang H; Partyka K; Kletter D; Hsueh P; Ensink E; Kc B; Hostetter G -
Identification of a fourth mannose 6-phosphate binding site in the cation-independent mannose 6-phosphate receptor.
Glycobiology Volume: 25 Page(s): 591 - 606
06/01/2015 Authors: Olson LJ; Castonguay AC; Lasanajak Y; Peterson FC; Cummings RD; Smith DF; Dahms NM -
Intact reducing glycan promotes the specific immune response to lacto-N-neotetraose-BSA neoglycoconjugates.
Bioconjug Chem Volume: 26 Page(s): 559 - 571
03/18/2015 Authors: Prasanphanich NS; Song X; Heimburg-Molinaro J; Luyai AE; Lasanajak Y; Cutler CE; Smith DF; Cummings RD -
The human IgG anti-carbohydrate repertoire exhibits a universal architecture and contains specificity for microbial attachment sites.
Sci Transl Med Volume: 7 Page(s): 269ra1
01/07/2015 Authors: Schneider C; Smith DF; Cummings RD; Boligan KF; Hamilton RG; Bochner BS; Miescher S; Simon H-U; Pashov A; Vassilev T -
Examining galectin binding specificity using glycan microarrays.
Methods Mol Biol Volume: 1207 Page(s): 115 - 131
01/01/2015 Authors: Arthur CM; Rodrigues LC; Baruffi MD; Sullivan HC; Heimburg-Molinaro J; Smith DF; Cummings RD; Stowell SR -
Glycoarrays with engineered phages displaying structurally diverse oligosaccharides enable high-throughput detection of glycan-protein interactions.
Biotechnol J Volume: 10 Page(s): 199 - 209
01/01/2015 Authors: elik E; Ollis AA; Lasanajak Y; Fisher AC; Gr G; Smith DF; DeLisa MP -
A receptor-binding protein of Campylobacter jejuni bacteriophage NCTC 12673 recognizes flagellin glycosylated with acetamidino-modified pseudaminic acid.
Mol Microbiol Volume: 95 Page(s): 101 - 115
01/01/2015 Authors: Javed MA; van Alphen LB; Sacher J; Ding W; Kelly J; Nargang C; Smith DF; Cummings RD; Szymanski CM -
GlycoPattern: a web platform for glycan array mining.
Bioinformatics Volume: 30 Page(s): 3417 - 3418
12/01/2014 Authors: Agravat SB; Saltz JH; Cummings RD; Smith DF -
Structural characterization by multistage mass spectrometry (MSn) of human milk glycans recognized by human rotaviruses.
Mol Cell Proteomics Volume: 13 Page(s): 2961 - 2974
11/01/2014 Authors: Ashline DJ; Yu Y; Lasanajak Y; Song X; Hu L; Ramani S; Prasad V; Estes MK; Cummings RD; Smith DF -
Human milk contains novel glycans that are potential decoy receptors for neonatal rotaviruses.
Mol Cell Proteomics Volume: 13 Page(s): 2944 - 2960
11/01/2014 Authors: Yu Y; Lasanajak Y; Song X; Hu L; Ramani S; Mickum ML; Ashline DJ; Prasad BVV; Estes MK; Reinhold VN -
Novel Strategy to Release and Tag Glycans from Glycoproteins and Glycosphingolipids for Functional Glycomics
Volume: 24 Page(s): 1115 - 1115
11/01/2014 Authors: Song X; Ju H; Zhao C; Lasanajak Y; Smith DF; Cummings RD -
Developing unique glycan binding reagents using an ancient immune system
Volume: 24 Page(s): 1135 - 1136
11/01/2014 Authors: McKitrick T; Heimburg-Molinaro J; Herrin B; Smith D; Cooper M; Cummings R -
Novel Interactions of Human Milk Glycans with Human Galectins
Volume: 24 Page(s): 1130 - 1130
11/01/2014 Authors: Noll A; Yu Y; Lasanajak Y; Gourdine J-P; Smith D; Cummings R -
Genetic determinants of common epilepsies: a meta-analysis of genome-wide association studies.
Lancet Neurol Volume: 13 Page(s): 893 - 903
09/01/2014 Authors: International League Against Epilepsy Consortium on Complex Epilepsies. Electronic address: epilepsy-austin@unimelb.edu.au -
Investigating virus-glycan interactions using glycan microarrays.
Curr Opin Virol Volume: 7 Page(s): 79 - 87
08/01/2014 Authors: Smith DF; Cummings RD -
Functional Glycomics - Defining Glycan Recognition by Proteins
MOLECULAR & CELLULAR PROTEOMICS Volume: 13 Page(s): S42 - S42
08/01/2014 Authors: Cummings RD; Smith DF; Song X -
Differential expression of anti-glycan antibodies in schistosome-infected humans, rhesus monkeys and mice.
Glycobiology Volume: 24 Page(s): 602 - 618
07/01/2014 Authors: Luyai AE; Heimburg-Molinaro J; Prasanphanich NS; Mickum ML; Lasanajak Y; Song X; Nyame AK; Wilkins P; Rivera-Marrero CA; Smith DF -
Immunization with recombinantly expressed glycan antigens from Schistosoma mansoni induces glycan-specific antibodies against the parasite.
Glycobiology Volume: 24 Page(s): 619 - 637
07/01/2014 Authors: Prasanphanich NS; Luyai AE; Song X; Heimburg-Molinaro J; Mandalasi M; Mickum M; Smith DF; Nyame AK; Cummings RD -
Shotgun glycomics of pig lung identifies natural endogenous receptors for influenza viruses.
Proc Natl Acad Sci U S A Volume: 111 Page(s): E2241 - E2250
06/03/2014 Authors: Byrd-Leotis L; Liu R; Bradley KC; Lasanajak Y; Cummings SF; Song X; Heimburg-Molinaro J; Galloway SE; Culhane MR; Smith DF -
Cross-platform comparison of glycan microarray formats.
Glycobiology Volume: 24 Page(s): 507 - 517
06/01/2014 Authors: Wang L; Cummings RD; Smith DF; Huflejt M; Campbell CT; Gildersleeve JC; Gerlach JQ; Kilcoyne M; Joshi L; Serna S -
Microbial glycan microarrays define key features of host-microbial interactions.
Nat Chem Biol Volume: 10 Page(s): 470 - 476
06/01/2014 Authors: Stowell SR; Arthur CM; McBride R; Berger O; Razi N; Heimburg-Molinaro J; Rodrigues LC; Gourdine J-P; Noll AJ; von Gunten S -
MIRAGE: the minimum information required for a glycomics experiment.
Glycobiology Volume: 24 Page(s): 402 - 406
05/01/2014 Authors: York WS; Agravat S; Aoki-Kinoshita KF; McBride R; Campbell MP; Costello CE; Dell A; Feizi T; Haslam SM; Karlsson N -
Chemistry of natural glycan microarrays.
Curr Opin Chem Biol Volume: 18 Page(s): 70 - 77
02/01/2014 Authors: Song X; Heimburg-Molinaro J; Cummings RD; Smith DF -
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CURRENT OPINION IN CHEMICAL BIOLOGY Volume: 18 Page(s): V - VI
02/01/2014 Authors: Matson RS; Smith DF -
Profiling of glycan receptors for minute virus of mice in permissive cell lines towards understanding the mechanism of cell recognition.
PLoS One Volume: 9 Page(s): e86909
01/01/2014 Authors: Halder S; Cotmore S; Heimburg-Molinaro J; Smith DF; Cummings RD; Chen X; Trollope AJ; North SJ; Haslam SM; Dell A -
Glycan array analysis of influenza H1N1 binding and release.
Cancer Biomark Volume: 14 Page(s): 43 - 53
01/01/2014 Authors: Gulati S; Lasanajak Y; Smith DF; Cummings RD; Air GM -
Mice deficient in the St3gal3 gene product 2,3 sialyltransferase (ST3Gal-III) exhibit enhanced allergic eosinophilic airway inflammation.
J Allergy Clin Immunol Volume: 133 Page(s): 240-7.e1-3
01/01/2014 Authors: Kiwamoto T; Brummet ME; Wu F; Motari MG; Smith DF; Schnaar RL; Zhu Z; Bochner BS -
Mutation tryptophan to leucine at position 222 of haemagglutinin could facilitate H3N2 influenza A virus infection in dogs.
J Gen Virol Volume: 94 Page(s): 2599 - 2608
12/01/2013 Authors: Yang G; Li S; Blackmon S; Ye J; Bradley KC; Cooley J; Smith D; Hanson L; Cardona C; Steinhauer DA -
Novel cleavage of reductively aminated glycan-tags by N-bromosuccinimide to regenerate free, reducing glycans.
ACS Chem Biol Volume: 8 Page(s): 2478 - 2483
11/15/2013 Authors: Song X; Johns BA; Ju H; Lasanajak Y; Zhao C; Smith DF; Cummings RD -
Human Milk Glycans Are Potential Receptor Decoys During Neonatal Rotavirus Infection
Volume: 23 Page(s): 1343 - 1344
11/01/2013 Authors: Yu Y; Lasanajak Y; Song X; Hu L; Ramani S; Ashline DJ; Prasad BVV; Estes MK; Reinhold VN; Cummings RD -
Tn and sialyl-Tn antigens, aberrant O-glycomics as human disease markers.
Proteomics Clin Appl Volume: 7 Page(s): 618 - 631
10/01/2013 Authors: Ju T; Wang Y; Aryal RP; Lehoux SD; Ding X; Kudelka MR; Cutler C; Zeng J; Wang J; Sun X -
Structure and receptor binding specificity of hemagglutinin H13 from avian influenza A virus H13N6.
J Virol Volume: 87 Page(s): 9077 - 9085
08/01/2013 Authors: Lu X; Qi J; Shi Y; Wang M; Smith DF; Heimburg-Molinaro J; Zhang Y; Paulson JC; Xiao H; Gao GF -
Development and characterization of a specific IgG monoclonal antibody toward the Lewis x antigen using splenocytes of Schistosoma mansoni-infected mice.
Glycobiology Volume: 23 Page(s): 877 - 892
07/01/2013 Authors: Mandalasi M; Dorabawila N; Smith DF; Heimburg-Molinaro J; Cummings RD; Nyame AK -
The VP8* domain of neonatal rotavirus strain G10P[11] binds to type II precursor glycans.
J Virol Volume: 87 Page(s): 7255 - 7264
07/01/2013 Authors: Ramani S; Cortes-Penfield NW; Hu L; Crawford SE; Czako R; Smith DF; Kang G; Ramig RF; Le Pendu J; Prasad BVV -
Application of microarrays for deciphering the structure and function of the human glycome.
Mol Cell Proteomics Volume: 12 Page(s): 902 - 912
04/01/2013 Authors: Smith DF; Cummings RD -
Structural studies of the interaction of Crataeva tapia bark protein with heparin and other glycosaminoglycans.
Biochemistry Volume: 52 Page(s): 2148 - 2156
03/26/2013 Authors: Zhang F; Walcott B; Zhou D; Gustchina A; Lasanajak Y; Smith DF; Ferreira RS; Correia MTS; Paiva PMG; Bovin NV -
Selective breeding for helplessness in rats alters the metabolic profile of the hippocampus and frontal cortex: a 1H-MRS study at 9.4 T.
Int J Neuropsychopharmacol Volume: 16 Page(s): 199 - 212
02/01/2013 Authors: Schulz D; Smith D; Yu M; Lee H; Henn FA -
Human H3N2 Influenza Viruses Isolated from 1968 To 2012 Show Varying Preference for Receptor Substructures with No Apparent Consequences for Disease or Spread.
PLoS One Volume: 8 Page(s): e66325
01/01/2013 Authors: Gulati S; Smith DF; Cummings RD; Couch RB; Griesemer SB; St George K; Webster RG; Air GM -
Computational screening of the human TF-glycome provides a structural definition for the specificity of anti-tumor antibody JAA-F11.
PLoS One Volume: 8 Page(s): e54874
01/01/2013 Authors: Tessier MB; Grant OC; Heimburg-Molinaro J; Smith D; Jadey S; Gulick AM; Glushka J; Deutscher SL; Rittenhouse-Olson K; Woods RJ -
Functional glycomic analysis of human milk glycans reveals the presence of virus receptors and embryonic stem cell biomarkers.
J Biol Chem Volume: 287 Page(s): 44784 - 44799
12/28/2012 Authors: Yu Y; Mishra S; Song X; Lasanajak Y; Bradley KC; Tappert MM; Air GM; Steinhauer DA; Halder S; Cotmore S -
Characterization of the FLDNF glycan epitope in Schistosoma manonsi and a semi-synthetic approach for heterologous expression
Volume: 22 Page(s): 1541 - 1541
11/01/2012 Authors: Mickum ML; Dorabawila N; Heimburg-Molinaro J; Lasanajak Y; Mandalasi M; Song X; Smith DF; Nyame AK; Cummings RD -
Functional glycomic studies of human milk glycans reveals presence of embryonic stem cell biomarkers and virus receptors
Volume: 22 Page(s): 1616 - 1616
11/01/2012 Authors: Yu Y; Mishra S; Song X; Lasanajak Y; Bradley KC; Tappert M; Air GM; Steinhauer DA; Halder S; Cotmore S -
Shotgun glycan glycomics studies of influenza virus pathogenesis
Volume: 22 Page(s): 1610 - 1610
11/01/2012 Authors: Liu R; Bradley K; Byrd-Leotis L; Cummings SF; Smith DF; Steinhauer D; Cummings RD -
Cross-platform comparison of carbohydrate microarrays: Six groups and five lectins
Volume: 22 Page(s): 1647 - 1647
11/01/2012 Authors: Wang L; Campbell C; Cummings R; Gerlach JQ; Gildersleeve JC; Huflejt M; Joshi L; Kane M; Pieters R; Reichardt N -
Automated motif discovery from glycan array data.
OMICS Volume: 16 Page(s): 497 - 512
10/01/2012 Authors: Cholleti SR; Agravat S; Morris T; Saltz JH; Song X; Cummings RD; Smith DF -
Nonenzymatic release of free reducing glycans from glycosphingolipids.
Anal Biochem Volume: 429 Page(s): 82 - 87
10/01/2012 Authors: Song X; Smith DF; Cummings RD -
Expression analysis of a type S2 EUL-related lectin from rice in Pichia pastoris.
Glycoconj J Volume: 29 Page(s): 467 - 479
10/01/2012 Authors: Al Atalah B; Roug P; Smith DF; Proost P; Lasanajak Y; Van Damme EJM -
Porphyromonas gingivalis fimbriae carbohydrate specificity assessment by glycomics.
FEMS Immunol Med Microbiol Volume: 66 Page(s): 83 - 87
10/01/2012 Authors: Sojar HT; Smith DF -
2G12/PGT-binding yeast glycoprotein Gp38 elicits mannose-specific HIV-1 Env cross-reactive antibodies
RETROVIROLOGY Volume: 9
09/13/2012 Authors: Zhang H; Fu H; Liu B; Luallen RJ; Doms RW; Smith DF; Geng Y -
The glycan-binding properties of the cation-independent mannose 6-phosphate receptor are evolutionary conserved in vertebrates.
Glycobiology Volume: 22 Page(s): 983 - 996
07/01/2012 Authors: Castonguay AC; Lasanajak Y; Song X; Olson LJ; Cummings RD; Smith DF; Dahms NM -
Cross-comparison of protein recognition of sialic acid diversity on two novel sialoglycan microarrays.
J Biol Chem Volume: 287 Page(s): 22593 - 22608
06/29/2012 Authors: Padler-Karavani V; Song X; Yu H; Hurtado-Ziola N; Huang S; Muthana S; Chokhawala HA; Cheng J; Verhagen A; Langereis MA -
Deciphering structural elements of mucin glycoprotein recognition.
ACS Chem Biol Volume: 7 Page(s): 1031 - 1039
06/15/2012 Authors: Borgert A; Heimburg-Molinaro J; Song X; Lasanajak Y; Ju T; Liu M; Thompson P; Ragupathi G; Barany G; Smith DF -
Pathogen array reveals innate immune defense against molecular mimicry
Volume: 188
05/01/2012 Authors: Stowell S; Arthur C; McBride R; Smith D; Paulson J; Cummings R -
Cell attachment protein VP8* of a human rotavirus specifically interacts with A-type histo-blood group antigen.
Nature Volume: 485 Page(s): 256 - 259
04/15/2012 Authors: Hu L; Crawford SE; Czako R; Cortes-Penfield NW; Smith DF; Le Pendu J; Estes MK; Prasad BVV -
Bivalent carbohydrate binding is required for biological activity of Clitocybe nebularis lectin (CNL), the N,N'-diacetyllactosediamine (GalNAc1-4GlcNAc, LacdiNAc)-specific lectin from basidiomycete C. nebularis.
J Biol Chem Volume: 287 Page(s): 10602 - 10612
03/23/2012 Authors: Pohleven J; Renko M; Magister ; Smith DF; Knzler M; trukelj B; Turk D; Kos J; Saboti J -
Chemoenzymatic probes for detecting and imaging fucose-(1-2)-galactose glycan biomarkers.
J Am Chem Soc Volume: 134 Page(s): 4489 - 4492
03/14/2012 Authors: Chaubard J-L; Krishnamurthy C; Yi W; Smith DF; Hsieh-Wilson LC -
Fucose-binding lectin from opportunistic pathogen Burkholderia ambifaria binds to both plant and human oligosaccharidic epitopes.
J Biol Chem Volume: 287 Page(s): 4335 - 4347
02/03/2012 Authors: Audfray A; Claudinon J; Abounit S; Ruvon-Clouet N; Larson G; Smith DF; Wimmerov M; Le Pendu J; Rmer W; Varrot A -
Similarities And Differences Between Lung Ligands For Mouse Siglec-f And Human Siglec-8
Volume: 129 Page(s): AB49 - AB49
02/01/2012 Authors: Kiwamoto T; Na HJ; Brummet ME; Smith DF; Bochner BS -
Probing virus-glycan interactions using glycan microarrays.
Methods Mol Biol Volume: 808 Page(s): 251 - 267
01/01/2012 Authors: Heimburg-Molinaro J; Tappert M; Song X; Lasanajak Y; Air G; Smith DF; Cummings RD -
Preparation of a mannose-6-phosphate glycan microarray through fluorescent derivatization, phosphorylation, and immobilization of natural high-mannose N-glycans and application in ligand identification of P-type lectins.
Methods Mol Biol Volume: 808 Page(s): 137 - 148
01/01/2012 Authors: Song X; Heimburg-Molinaro J; Dahms NM; Smith DF; Cummings RD -
Glycan microarrays.
Methods Mol Biol Volume: 800 Page(s): 163 - 171
01/01/2012 Authors: Song X; Heimburg-Molinaro J; Smith DF; Cummings RD -
Analysis of influenza virus hemagglutinin receptor binding mutants with limited receptor recognition properties and conditional replication characteristics.
J Virol Volume: 85 Page(s): 12387 - 12398
12/01/2011 Authors: Bradley KC; Galloway SE; Lasanajak Y; Song X; Heimburg-Molinaro J; Yu H; Chen X; Talekar GR; Smith DF; Cummings RD -
Fixation of oligosaccharides to a surface may increase the susceptibility to human parainfluenza virus 1, 2, or 3 hemagglutinin-neuraminidase.
J Virol Volume: 85 Page(s): 12146 - 12159
12/01/2011 Authors: Tappert MM; Smith DF; Air GM -
Antibodies recognising sulfated carbohydrates are prevalent in systemic sclerosis and associated with pulmonary vascular disease.
Ann Rheum Dis Volume: 70 Page(s): 2218 - 2224
12/01/2011 Authors: Grader-Beck T; Boin F; von Gunten S; Smith D; Rosen A; Bochner BS -
Glycan microarray profiling of parasite infection sera identifies the LDNF glycan as a potential antigen for serodiagnosis of trichinellosis.
Exp Parasitol Volume: 129 Page(s): 221 - 226
11/01/2011 Authors: Aranzamendi C; Tefsen B; Jansen M; Chiumiento L; Bruschi F; Kortbeek T; Smith DF; Cummings RD; Pinelli E; Van Die I -
Use of Siglec-F-Fc and a Novel IgY Antibody Recognizing 6 '-sulfated-sialyl Lewis X to Identify Endogenous Lung Ligands for Siglec-F
Volume: 21 Page(s): 1484 - 1484
11/01/2011 Authors: Kiwamoto T; Na HJ; Brummet M; Finn MG; Smith D; Hong V; Polonskaya Z; Bovin NV; Hudson S; Bochner B -
GlycoPattern: A Platform for Motif Discovery and Glycan Array Exploration
Volume: 21 Page(s): 1470 - 1471
11/01/2011 Authors: Agravat S; Cholleti S; Morris T; Saltz J; Song X; Cummings R; Smith D -
Lectin activity of the nucleocytoplasmic EUL protein from Arabidopsis thaliana.
Biochem Biophys Res Commun Volume: 414 Page(s): 101 - 105
10/14/2011 Authors: Van Hove J; Fouquaert E; Smith DF; Proost P; Van Damme EJM -
A sialylated glycan microarray reveals novel interactions of modified sialic acids with proteins and viruses.
J Biol Chem Volume: 286 Page(s): 31610 - 31622
09/09/2011 Authors: Song X; Yu H; Chen X; Lasanajak Y; Tappert MM; Air GM; Tiwari VK; Cao H; Chokhawala HA; Zheng H -
Expression analysis of the nucleocytoplasmic lectin 'Orysata' from rice in Pichia pastoris.
FEBS J Volume: 278 Page(s): 2064 - 2079
06/01/2011 Authors: Al Atalah B; Fouquaert E; Vanderschaeghe D; Proost P; Balzarini J; Smith DF; Roug P; Lasanajak Y; Callewaert N; Van Damme EJM -
Comparison of the receptor binding properties of contemporary swine isolates and early human pandemic H1N1 isolates (Novel 2009 H1N1).
Virology Volume: 413 Page(s): 169 - 182
05/10/2011 Authors: Bradley KC; Jones CA; Tompkins SM; Tripp RA; Russell RJ; Gramer MR; Heimburg-Molinaro J; Smith DF; Cummings RD; Steinhauer DA -
Characterization of annexin A1 glycan binding reveals binding to highly sulfated glycans with preference for highly sulfated heparan sulfate and heparin.
Biochemistry Volume: 50 Page(s): 2650 - 2659
04/05/2011 Authors: Horlacher T; Noti C; de Paz JL; Bindschdler P; Hecht M-L; Smith DF; Fukuda MN; Seeberger PH -
Derivatization of free natural glycans for incorporation onto glycan arrays: derivatizing glycans on the microscale for microarray and other applications (ms# CP-10-0194).
Curr Protoc Chem Biol Volume: 3 Page(s): 53 - 63
04/01/2011 Authors: Song X; Heimburg-Molinaro J; Smith DF; Cummings RD -
Preparation and analysis of glycan microarrays.
Curr Protoc Protein Sci Volume: Chapter 12 Page(s): Unit12.10
04/01/2011 Authors: Heimburg-Molinaro J; Song X; Smith DF; Cummings RD -
Structural basis of molecular recognition of the Leishmania small hydrophilic endoplasmic reticulum-associated protein (SHERP) at membrane surfaces.
J Biol Chem Volume: 286 Page(s): 9246 - 9256
03/18/2011 Authors: Moore B; Miles AJ; Guerra-Giraldez C; Simpson P; Iwata M; Wallace BA; Matthews SJ; Smith DF; Brown KA -
Identification and characterization of endogenous galectins expressed in Madin Darby canine kidney cells.
J Biol Chem Volume: 286 Page(s): 6780 - 6790
02/25/2011 Authors: Poland PA; Rondanino C; Kinlough CL; Heimburg-Molinaro J; Arthur CM; Stowell SR; Smith DF; Hughey RP -
Shotgun glycomics: a microarray strategy for functional glycomics.
Nat Methods Volume: 8 Page(s): 85 - 90
01/01/2011 Authors: Song X; Lasanajak Y; Xia B; Heimburg-Molinaro J; Rhea JM; Ju H; Zhao C; Molinaro RJ; Cummings RD; Smith DF -
Glycan arrays to decipher the specificity of plant lectins.
Volume: 705 Page(s): 757 - 767
01/01/2011 Authors: Van Damme EJM; Smith DF; Cummings R; Peumans WJ -
An Igg Monoclonal Antibody from Spleens of Schistosoma mansoni Infected Mice Binds Lewis X Epitopes on Schistosomes and Human Leukocytes
Volume: 20 Page(s): 1532 - 1532
11/01/2010 Authors: Mandalasi M; Dorabawila N; Smith D; Cummings RD; Nyame K -
Shotgun Glycomics: Functional Identification of Glycan Determinants through a Microarray Strategy using Fluorescently Tagged Glycans
Volume: 20 Page(s): 1466 - 1466
11/01/2010 Authors: Song X; Lasanajak Y; Xia B; Heimburg-Molinaro J; Rhea J; Ju H; Zhao C; Molinaro R; Cummings R; Smith D -
Galectins Recognize and Kill Bacteria Expressing Host-Like Antigens
Volume: 20 Page(s): 1533 - 1533
11/01/2010 Authors: Stowell S; Arthur C; Dias-Baruffi M; Rodrigues L; Gourdine J-P; Heimburg-Molinaro J; Ju T; Molinaro R; Rivera-Marrero C; Xia B -
Elements of Mucin Glycoprotein Recognition
Volume: 20 Page(s): 1518 - 1519
11/01/2010 Authors: Heimburg-Molinaro J; Liu M; Lasanajak Y; Smith D; Cummings R; Live D -
Mutational analysis of the carbohydrate binding activity of the tobacco lectin.
Glycoconj J Volume: 27 Page(s): 613 - 623
08/01/2010 Authors: Schouppe D; Roug P; Lasanajak Y; Barre A; Smith DF; Proost P; Van Damme EJM -
Innate immune lectins kill bacteria expressing blood group antigen.
Nat Med Volume: 16 Page(s): 295 - 301
03/01/2010 Authors: Stowell SR; Arthur CM; Dias-Baruffi M; Rodrigues LC; Gourdine J-P; Heimburg-Molinaro J; Ju T; Molinaro RJ; Rivera-Marrero C; Xia B -
Antibodies against Manalpha1,2-Manalpha1,2-Man oligosaccharide structures recognize envelope glycoproteins from HIV-1 and SIV strains.
Glycobiology Volume: 20 Page(s): 280 - 286
03/01/2010 Authors: Luallen RJ; Agrawal-Gamse C; Fu H; Smith DF; Doms RW; Geng Y -
Carbohydrate recognition properties of human ficolins: glycan array screening reveals the sialic acid binding specificity of M-ficolin.
J Biol Chem Volume: 285 Page(s): 6612 - 6622
02/26/2010 Authors: Gout E; Garlatti V; Smith DF; Lacroix M; Dumestre-Prard C; Lunardi T; Martin L; Cesbron J-Y; Arlaud GJ; Gaboriaud C -
Use of glycan microarrays to explore specificity of glycan-binding proteins.
Methods Enzymol Volume: 480 Page(s): 417 - 444
01/01/2010 Authors: Smith DF; Song X; Cummings RD -
Generation of a natural glycan microarray using 9-fluorenylmethyl chloroformate (FmocCl) as a cleavable fluorescent tag.
Anal Biochem Volume: 395 Page(s): 151 - 160
12/15/2009 Authors: Song X; Lasanajak Y; Rivera-Marrero C; Luyai A; Willard M; Smith DF; Cummings RD -
Cation-independent mannose 6-phosphate receptor: a composite of distinct phosphomannosyl binding sites.
J Biol Chem Volume: 284 Page(s): 35215 - 35226
12/11/2009 Authors: Bohnsack RN; Song X; Olson LJ; Kudo M; Gotschall RR; Canfield WM; Cummings RD; Smith DF; Dahms NM -
Glycan microarray analysis of P-type lectins reveals distinct phosphomannose glycan recognition.
J Biol Chem Volume: 284 Page(s): 35201 - 35214
12/11/2009 Authors: Song X; Lasanajak Y; Olson LJ; Boonen M; Dahms NM; Kornfeld S; Cummings RD; Smith DF -
Changes of the receptor-binding properties of influenza B virus B/Victoria/504/2000 during adaptation in chicken eggs.
Virology Volume: 394 Page(s): 218 - 226
11/25/2009 Authors: Lugovtsev VY; Smith DF; Weir JP -
Investigating the Specificity of Influenza Neuraminidase
Volume: 19 Page(s): 1359 - 1359
11/01/2009 Authors: Air GM; Tappert M; Gulati S; Lasanajak Y; Smith DF; Cummings RD -
Fluorescent Glycosylamides Produced by Microscale Derivatization of Free Glycans for Natural Glycan Microarrays
Volume: 19 Page(s): 1347 - 1347
11/01/2009 Authors: Song X; Lasanajak Y; Xia B; Smith D; Cummings R -
Defining Mucin Recognition with a Glycopeptide Microarray
Volume: 19 Page(s): 1352 - 1352
11/01/2009 Authors: Heimburg-Molinaro J; Lasanajak Y; Ju T; Liu M; Cummings R; Smith D; Live D -
Facile Preparation of Fluorescent Neo-Glycoproteins using P-Nitrophenyl Anthranilate as a Heterobifunctional Linker
Volume: 19 Page(s): 1348 - 1349
11/01/2009 Authors: Luyai A; Lasanajak Y; Smith D; Cummings R; Song X -
Glycan Microarray Analysis of P-Type Lectins Reveals Distinct Phospho-Mannose Glycan Recognition
Volume: 19 Page(s): 1353 - 1353
11/01/2009 Authors: Song X; Lasanajak Y; Olson L; Boonen M; Dahms N; Kornfeld S; Cummings R; Smith D -
Generation of a Natural Glycan Microarray using 9-Fluorenylmethyl Chloroformate (Fmoccl) as a Cleavable Fluorescent Tag
Volume: 19 Page(s): 1349 - 1349
11/01/2009 Authors: Song X; Lasanajak Y; Rivera-Marrero C; Luyai A; Willard M; Smith D; Cummings R -
Identification of Schistosoma Mansoni Egg Immunodominant Glycan Antigens by the Use of Natural Glycan Microarrays
Volume: 19 Page(s): 1357 - 1357
11/01/2009 Authors: Rivera-Marrero C; Song X; Lasanajak Y; Luyai A; Willard M; Wilkins P; Secor WE; Smith D; Cummings R -
Cation-Independent Mannose 6-Phosphate Receptor: A Composite of Distinct Phosphomannosyl Binding Sites
Volume: 19 Page(s): 1293 - 1293
11/01/2009 Authors: Dahms N; Bohnsack R; Song X; Olson L; Kudo M; Gotschall R; Canfield W; Cummings R; Smith D -
Fluorescent glycosylamides produced by microscale derivatization of free glycans for natural glycan microarrays.
ACS Chem Biol Volume: 4 Page(s): 741 - 750
09/18/2009 Authors: Song X; Lasanajak Y; Xia B; Smith DF; Cummings RD -
Carbohydrate recognition properties of human ficolins: Glycan array screening provides insights into the sialic acid binding specificity of M-ficolin
Volume: 46 Page(s): 2819 - 2819
09/01/2009 Authors: Gout E; Garlatti V; Smith D; Lacroix M; Lunardi T; Arlaud GJ; Gaboriaud C; Thielens NM -
Facile preparation of fluorescent neoglycoproteins using p-nitrophenyl anthranilate as a heterobifunctional linker.
Bioconjug Chem Volume: 20 Page(s): 1618 - 1624
08/19/2009 Authors: Luyai A; Lasanajak Y; Smith DF; Cummings RD; Song X -
Intravenous immunoglobulin contains a broad repertoire of anticarbohydrate antibodies that is not restricted to the IgG2 subclass.
J Allergy Clin Immunol Volume: 123 Page(s): 1268 - 76.e15
06/01/2009 Authors: von Gunten S; Smith DF; Cummings RD; Riedel S; Miescher S; Schaub A; Hamilton RG; Bochner BS -
Glycan reductive isotope labeling for quantitative glycomics.
Anal Biochem Volume: 387 Page(s): 162 - 170
04/15/2009 Authors: Xia B; Feasley CL; Sachdev GP; Smith DF; Cummings RD -
Seasonal influenza virus isolates vary in binding specificity to sialylated glycans
Volume: 237 Page(s): 704 - 704
03/22/2009 Authors: Air G; Gulati S; Tappert M; Smith DF; Cummings R -
Related lectins from snowdrop and maize differ in their carbohydrate-binding specificity.
Biochem Biophys Res Commun Volume: 380 Page(s): 260 - 265
03/06/2009 Authors: Fouquaert E; Smith DF; Peumans WJ; Proost P; Balzarini J; Savvides SN; Damme EJMV -
Identification of mRNA splicing factors as the endothelial receptor for carbohydrate-dependent lung colonization of cancer cells.
Proc Natl Acad Sci U S A Volume: 106 Page(s): 3095 - 3100
03/03/2009 Authors: Hatakeyama S; Sugihara K; Nakayama J; Akama TO; Wong S-MA; Kawashima H; Zhang J; Smith DF; Ohyama C; Fukuda M -
Deletions of neuraminidase and resistance to oseltamivir may be a consequence of restricted receptor specificity in recent H3N2 influenza viruses.
Virol J Volume: 6 Page(s): 22
02/14/2009 Authors: Gulati S; Smith DF; Air GM -
Novel fluorescent glycan microarray strategy reveals ligands for galectins.
Chem Biol Volume: 16 Page(s): 36 - 47
01/30/2009 Authors: Song X; Xia B; Stowell SR; Lasanajak Y; Smith DF; Cummings RD -
Glycan-Binding Proteins and Glycan Microarrays
Page(s): 139 - 160
01/01/2009 Authors: Smith DF; Cummings RD -
Isotopic Labeling of Glycans for Quantitative Glycomics
Page(s): 83 - 93
01/01/2009 Authors: Cummings RD; Smith DF -
Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin.
Nature Volume: 456 Page(s): 648 - 652
12/04/2008 Authors: Byres E; Paton AW; Paton JC; Lfling JC; Smith DF; Wilce MCJ; Talbot UM; Chong DC; Yu H; Huang S -
Distinct Glycan Recognition by Galectins Underscores Unique Roles in Immune Regulation
Volume: 18 Page(s): 1004 - 1004
11/01/2008 Authors: Stowell SR; Arthur CM; Ju T; Smith DF; Cummings RD -
Probing the Function of the Hemagglutinin-Neuraminidase Protein of the Human Parainfluenza Viruses
Volume: 18 Page(s): 985 - 985
11/01/2008 Authors: Tappert MA; Gulati S; Smith DF; Cummings RD; Air GM -
Role of cellular heparan sulfate proteoglycans in infection of human adenovirus serotype 3 and 35.
PLoS Pathog Volume: 4 Page(s): e1000189
10/01/2008 Authors: Tuve S; Wang H; Jacobs JD; Yumul RC; Smith DF; Lieber A -
Dimeric Galectin-8 induces phosphatidylserine exposure in leukocytes through polylactosamine recognition by the C-terminal domain.
J Biol Chem Volume: 283 Page(s): 20547 - 20559
07/18/2008 Authors: Stowell SR; Arthur CM; Slanina KA; Horton JR; Smith DF; Cummings RD -
Characterization of a streptococcal cholesterol-dependent cytolysin with a lewis y and b specific lectin domain.
Biochemistry Volume: 47 Page(s): 7097 - 7107
07/08/2008 Authors: Farrand S; Hotze E; Friese P; Hollingshead SK; Smith DF; Cummings RD; Dale GL; Tweten RK -
An engineered Saccharomyces cerevisiae strain binds the broadly neutralizing human immunodeficiency virus type 1 antibody 2G12 and elicits mannose-specific gp120-binding antibodies.
J Virol Volume: 82 Page(s): 6447 - 6457
07/01/2008 Authors: Luallen RJ; Lin J; Fu H; Cai KK; Agrawal C; Mboudjeka I; Lee F-H; Montefiori D; Smith DF; Doms RW -
Functional characterization of HFR1, a high-mannose N-glycan-specific wheat lectin induced by Hessian fly larvae.
Plant Physiol Volume: 147 Page(s): 1412 - 1426
07/01/2008 Authors: Subramanyam S; Smith DF; Clemens JC; Webb MA; Sardesai N; Williams CE -
The "old" Euonymus europaeus agglutinin represents a novel family of ubiquitous plant proteins.
Plant Physiol Volume: 147 Page(s): 1316 - 1324
07/01/2008 Authors: Fouquaert E; Peumans WJ; Smith DF; Proost P; Savvides SN; Van Damme EJM -
Glycan microarray analysis of Candida glabrata adhesin ligand specificity.
Mol Microbiol Volume: 68 Page(s): 547 - 559
05/01/2008 Authors: Zupancic ML; Frieman M; Smith D; Alvarez RA; Cummings RD; Cormack BP -
Galectin-1, -2, and -3 exhibit differential recognition of sialylated glycans and blood group antigens.
J Biol Chem Volume: 283 Page(s): 10109 - 10123
04/11/2008 Authors: Stowell SR; Arthur CM; Mehta P; Slanina KA; Blixt O; Leffler H; Smith DF; Cummings RD -
A novel mechanism for LSECtin binding to Ebola virus surface glycoprotein through truncated glycans.
J Biol Chem Volume: 283 Page(s): 593 - 602
01/04/2008 Authors: Powlesland AS; Fisch T; Taylor ME; Smith DF; Tissot B; Dell A; Phlmann S; Drickamer K -
Quantifiable fluorescent glycan microarrays.
Glycoconj J Volume: 25 Page(s): 15 - 25
01/01/2008 Authors: Song X; Xia B; Lasanajak Y; Smith DF; Cummings RD -
Metabolomics of neural progenitor cells: a novel approach to biomarker discovery.
Volume: 73 Page(s): 389 - 401
01/01/2008 Authors: Maleti-Savati M; Vingara LK; Manganas LN; Li Y; Zhang S; Sierra A; Hazel R; Smith D; Wagshul ME; Henn F -
Investigation of L-ficolin binding specificity
Volume: 44 Page(s): 3959 - 3959
09/01/2007 Authors: Krarup A; Girija UV; Mitchell DA; Smith DF; Sim RB -
Immunization by avian H5 influenza hemagglutinin mutants with altered receptor binding specificity.
Science Volume: 317 Page(s): 825 - 828
08/10/2007 Authors: Yang Z-Y; Wei C-J; Kong W-P; Wu L; Xu L; Smith DF; Nabel GJ -
Human parainfluenza viruses hPIV1 and hPIV3 bind oligosaccharides with alpha2-3-linked sialic acids that are distinct from those bound by H5 avian influenza virus hemagglutinin.
J Virol Volume: 81 Page(s): 8341 - 8345
08/01/2007 Authors: Amonsen M; Smith DF; Cummings RD; Air GM -
Affinity of galectin-8 and its carbohydrate recognition domains for ligands in solution and at the cell surface.
Glycobiology Volume: 17 Page(s): 663 - 676
06/01/2007 Authors: Carlsson S; Oberg CT; Carlsson MC; Sundin A; Nilsson UJ; Smith D; Cummings RD; Almkvist J; Karlsson A; Leffler H -
Phylogenetic and specificity studies of two-domain GNA-related lectins: generation of multispecificity through domain duplication and divergent evolution.
Biochem J Volume: 404 Page(s): 51 - 61
05/15/2007 Authors: Van Damme EJM; Nakamura-Tsuruta S; Smith DF; Ongenaert M; Winter HC; Roug P; Goldstein IJ; Mo H; Kominami J; Culerrier R -
Receptor binding specificity of recent human H3N2 influenza viruses.
Virol J Volume: 4 Page(s): 42
05/09/2007 Authors: Kumari K; Gulati S; Smith DF; Gulati U; Cummings RD; Air GM -
Alpha 2,3-sialyltransferase-IV is essential for L-selectin ligand function in inflammation.
Eur J Immunol Volume: 36 Page(s): 3207 - 3215
12/01/2006 Authors: Sperandio M; Frommhold D; Babushkina I; Ellies LG; Olson TS; Smith ML; Fritzsching B; Pauly E; Smith DF; Nobiling R -
Sialic acid binding and release in myxoviruses
Volume: 16 Page(s): 1147 - 1147
11/01/2006 Authors: Gulati S; Amonsen M; Kumari K; Veeraprame H; Alvarez R; Smith DF; Cummings RD -
Induction of LFA-1-dependent neutrophil rolling on ICAM-1 by engagement of E-selectin.
Microcirculation Volume: 13 Page(s): 99 - 109
03/01/2006 Authors: Chesnutt BC; Smith DF; Raffler NA; Smith ML; White EJ; Ley K -
Expression of human H-type alpha1,2-fucosyltransferase encoding for blood group H(O) antigen in Chinese hamster ovary cells. Evidence for preferential fucosylation and truncation of polylactosamine sequences.
J Biol Chem Volume: 272 Page(s): 2089 - 2097
01/24/1997 Authors: Prieto PA; Larsen RD; Cho M; Rivera HN; Shilatifard A; Lowe JB; Cummings RD; Smith DF -
Immobilized Lotus tetragonolobus agglutinin binds oligosaccharides containing the Le(x) determinant.
Glycoconj J Volume: 14 Page(s): 45 - 55
01/01/1997 Authors: Yan L; Wilkins PP; Alvarez-Manilla G; Do SI; Smith DF; Cummings RD -
alpha1,4-Fucosyltransferase activity in human serum and saliva.
Arch Biochem Biophys Volume: 335 Page(s): 109 - 117
11/01/1996 Authors: DeBose-Boyd RA; Nyame AK; Smith DF; Cummings RD -
Remodeling of mouse milk glycoconjugates by transgenic expression of a human glycosyltransferase.
J Biol Chem Volume: 270 Page(s): 29515 - 29519
12/08/1995 Authors: Prieto PA; Mukerji P; Kelder B; Erney R; Gonzalez D; Yun JS; Smith DF; Moremen KW; Nardelli C; Pierce M -
Demonstration of a novel UDPGalNAc:GlcNAc beta 1-4 N-acetylgalactosaminyltransferase in extracts of Schistosoma mansoni.
J Parasitol Volume: 80 Page(s): 884 - 890
12/01/1994 Authors: Srivatsan J; Smith DF; Cummings RD -
Determination of GDP-Fuc:Gal beta 1-4GlcNAc-R (Fuc to GlcNAc) alpha 1,3 fucosyltransferase activity by a solid-phase method.
Anal Biochem Volume: 223 Page(s): 111 - 118
11/15/1994 Authors: Yan L; Smith DF; Cummings RD -
The selectin family of carbohydrate-binding proteins: structure and importance of carbohydrate ligands for cell adhesion.
Bioessays Volume: 14 Page(s): 849 - 856
12/01/1992 Authors: Cummings RD; Smith DF -
A solid-phase assay for the activity of CMPNeuAc:Gal beta 1-4GlcNAc-R alpha-2,6-sialyltransferase.
Anal Biochem Volume: 206 Page(s): 430 - 436
11/01/1992 Authors: Mattox S; Walrath K; Ceiler D; Smith DF; Cummings RD -
The human blood fluke Schistosoma mansoni synthesizes glycoproteins containing the Lewis X antigen.
J Biol Chem Volume: 267 Page(s): 20196 - 20203
10/05/1992 Authors: Srivatsan J; Smith DF; Cummings RD -
Schistosoma mansoni synthesizes novel biantennary Asn-linked oligosaccharides containing terminal beta-linked N-acetylgalactosamine.
Glycobiology Volume: 2 Page(s): 445 - 452
10/01/1992 Authors: Srivatsan J; Smith DF; Cummings RD -
Identification of a specific glycoprotein ligand for P-selectin (CD62) on myeloid cells.
J Cell Biol Volume: 118 Page(s): 445 - 456
07/01/1992 Authors: Moore KL; Stults NL; Diaz S; Smith DF; Cummings RD; Varki A; McEver RP -
Use of recombinant biotinylated aequorin in microtiter and membrane-based assays: purification of recombinant apoaequorin from Escherichia coli.
Biochemistry Volume: 31 Page(s): 1433 - 1442
02/11/1992 Authors: Stults NL; Stocks NF; Rivera H; Gray J; McCann RO; O'Kane D; Cummings RD; Cormier MJ; Smith DF -
The human blood fluke Schistosoma mansoni synthesizes a novel type of glycosphingolipid.
J Biol Chem Volume: 267 Page(s): 2251 - 2257
02/05/1992 Authors: Makaaru CK; Damian RT; Smith DF; Cummings RD -
A microplate assay for analysis of solution-phase glycosyltransferase reactions: determination of kinetic constants.
Anal Biochem Volume: 199 Page(s): 286 - 292
12/01/1991 Authors: Mengeling BJ; Smith PL; Stults NL; Smith DF; Baenziger JU -
The selectin GMP-140 binds to sialylated, fucosylated lactosaminoglycans on both myeloid and nonmyeloid cells.
J Cell Biol Volume: 115 Page(s): 557 - 564
10/01/1991 Authors: Zhou Q; Moore KL; Smith DF; Varki A; McEver RP; Cummings RD -
Decreased biosynthesis of Forssman glycolipid after retinoic acid-induced differentiation of mouse F9 teratocarcinoma cells. Lectin-affinity chromatography of the glycolipid-derived oligosaccharide.
Carbohydr Res Volume: 213 Page(s): 155 - 168
06/25/1991 Authors: Clark GF; Gorbea CM; Cummings RD; Mattox S; Smith DF -
A solid-phase assay for beta-1,4-galactosyltransferase activity in human serum using recombinant aequorin.
Anal Biochem Volume: 194 Page(s): 185 - 191
04/01/1991 Authors: Zatta PF; Nyame K; Cormier MJ; Mattox SA; Prieto PA; Smith DF; Cummings RD -
LAMP-1 in CHO cells is a primary carrier of poly-N-acetyllactosamine chains and is bound preferentially by a mammalian S-type lectin.
Biochem Biophys Res Commun Volume: 173 Page(s): 1123 - 1128
12/31/1990 Authors: Do KY; Smith DF; Cummings RD -
Transfer and expression of a murine UDP-Gal:beta-D-Gal-alpha 1,3-galactosyltransferase gene in transfected Chinese hamster ovary cells. Competition reactions between the alpha 1,3-galactosyltransferase and the endogenous alpha 2,3-sialyltransferase.
J Biol Chem Volume: 265 Page(s): 6225 - 6234
04/15/1990 Authors: Smith DF; Larsen RD; Mattox S; Lowe JB; Cummings RD -
Complex-type asparagine-linked oligosaccharides in glycoproteins synthesized by Schistosoma mansoni adult males contain terminal beta-linked N-acetylgalactosamine.
J Biol Chem Volume: 264 Page(s): 3235 - 3243
02/25/1989 Authors: Nyame K; Smith DF; Damian RT; Cummings RD -
Lectin affinity chromatography of glycolipids and glycolipid-derived oligosaccharides.
Methods Enzymol Volume: 179 Page(s): 30 - 45
01/01/1989 Authors: Smith DF; Torres BV -
Separation of oligosaccharides containing terminal alpha-linked galactose residues by affinity chromatography on Griffonia simplicifolia I bound to concanavalin A-sepharose.
Anal Biochem Volume: 175 Page(s): 390 - 396
12/01/1988 Authors: Wang WC; Clark GF; Smith DF; Cummings RD -
A novel sialylhexasaccharide from human milk: purification by affinity chromatography on immobilized wheat germ agglutinin.
Arch Biochem Biophys Volume: 267 Page(s): 353 - 362
11/15/1988 Authors: Tarrago MT; Tucker KH; Van Halbeek H; Smith DF -
Purification of Forssman and human blood group A glycolipids by affinity chromatography on immobilized Helix pomatia lectin.
Anal Biochem Volume: 170 Page(s): 209 - 219
04/01/1988 Authors: Torres BV; Smith DF -
Glycolipid-lectin interactions: reactivity of lectins from Helix pomatia, Wisteria floribunda, and Dolichos biflorus with glycolipids containing N-acetylgalactosamine.
Arch Biochem Biophys Volume: 262 Page(s): 1 - 11
04/01/1988 Authors: Torres BV; McCrumb DK; Smith DF -
DETECTION OF METABOLICALLY LABELED FORSSMAN GLYCOLIPID IN F9 CELLS AND ITS LOSS DURING RETINOIC ACID-INDUCED DIFFERENTIATION
Volume: 2 Page(s): A1781 - A1781
03/25/1988 Authors: CLARK GF; CUMMINGS RD; SMITH DF -
III6NeuAcLc4Cer in human SW1116 colorectal carcinoma cells: a possible oncofetal antigen that is not dependent on Lewis gene expression.
Arch Biochem Biophys Volume: 258 Page(s): 315 - 323
11/01/1987 Authors: Law KL; Smith DF -
A novel sialylfucopentaose in human milk. Presence of this oligosaccharide is not dependent on expression of the secretor or Lewis fucosyltransferases.
J Biol Chem Volume: 262 Page(s): 12040 - 12047
09/05/1987 Authors: Smith DF; Prieto PA; McCrumb DK; Wang WC -
Toxin A from Clostridium difficile binds to rabbit erythrocyte glycolipids with terminal Gal alpha 1-3Gal beta 1-4GlcNAc sequences.
Arch Biochem Biophys Volume: 257 Page(s): 217 - 229
08/15/1987 Authors: Clark GF; Krivan HC; Wilkins TD; Smith DF -
Cell surface binding site for Clostridium difficile enterotoxin: evidence for a glycoconjugate containing the sequence Gal alpha 1-3Gal beta 1-4GlcNAc.
Infect Immun Volume: 53 Page(s): 573 - 581
09/01/1986 Authors: Krivan HC; Clark GF; Smith DF; Wilkins TD -
A new ganglioside in human meconium detected with antiserum against human milk sialyltetrasaccharide a.
Arch Biochem Biophys Volume: 249 Page(s): 243 - 253
08/15/1986 Authors: Prieto PA; Smith DF -
Rabbit antibodies against the human milk sialyloligosaccharide alditol of LS-tetrasaccharide a (NeuAc alpha 2-3Gal beta 1-3GlcNAc beta 1-3Gal beta 1-4GlcOH).
Arch Biochem Biophys Volume: 241 Page(s): 298 - 303
08/15/1985 Authors: Smith DF; Prieto PA; Torres BV -
A new ganglioside in human meconium detected by antiserum against the human milk sialyloligosaccharide, LS-tetrasaccharide b.
Arch Biochem Biophys Volume: 241 Page(s): 281 - 289
08/15/1985 Authors: Prieto PA; Smith DF -
A new sialyloligosaccharide from human milk: isolation and characterization using anti-oligosaccharide antibodies.
Arch Biochem Biophys Volume: 229 Page(s): 650 - 656
03/01/1984 Authors: Prieto PA; Smith DF -
Glycolipid-lectin interactions: detection by direct binding of 125I-lectins to thin layer chromatograms.
Biochem Biophys Res Commun Volume: 115 Page(s): 360 - 367
08/30/1983 Authors: Smith DF -
Detection of glycolipid ligands by direct binding of carbohydrate-binding proteins to thin-layer chromatograms.
Methods Enzymol Volume: 83 Page(s): 235 - 241
01/01/1982 Authors: Magnani JL; Brockhaus M; Smith DF; Ginsburg V -
Isolation of specific sugar sequences using carbohydrate-binding proteins.
Methods Enzymol Volume: 83 Page(s): 241 - 248
01/01/1982 Authors: Smith DF -
Glycolipids of cell surfaces: isolation of specific sugar sequences using carbohydrate-binding proteins.
Arch Biochem Biophys Volume: 209 Page(s): 52 - 56
06/01/1981 Authors: Smith DF; Magnani JL; Ginsburg V -
A monosialoganglioside is a monoclonal antibody-defined antigen of colon carcinoma.
Science Volume: 212 Page(s): 55 - 56
04/03/1981 Authors: Magnani JL; Brockhaus M; Smith DF; Ginsburg V; Blaszczyk M; Mitchell KF; Steplewski Z; Koprowski H -
Detection of gangliosides that bind cholera toxin: direct binding of 125I-labeled toxin to thin-layer chromatograms.
Anal Biochem Volume: 109 Page(s): 399 - 402
12/01/1980 Authors: Magnani JL; Smith DF; Ginsburg V -
A human Le(a-b+) blood group agglutinin prepared by polymerizing goat anti-lacto-N-difucohexaose I IgG.
Mol Immunol Volume: 17 Page(s): 1163 - 1166
09/01/1980 Authors: Warner CV; Smith DF; Zopf DA; Ginsburg V -
Antibodies against sialyloligosaccharides coupled to protein.
J Biol Chem Volume: 255 Page(s): 55 - 59
01/10/1980 Authors: Smith DF; Ginsburg V -
Le(b)-active glycolipid in human plasma: measurement by radioimmunoassay.
Arch Biochem Biophys Volume: 199 Page(s): 265 - 269
01/01/1980 Authors: Rohr TE; Smith DF; Zopf DA; Ginsburg V -
Fractionation of sialyl oligosaccharides of human milk by ion-exchange chromatography.
Anal Biochem Volume: 85 Page(s): 602 - 608
04/01/1978 Authors: Smith DF; Zopf DA; Ginsburg V -
Affinity purification of antibodies using oligosaccharide-phenethylamine derivaties coupled to Sepharose.
Methods Enzymol Volume: 50 Page(s): 171 - 175
01/01/1978 Authors: Zopf DA; Smith DF; Drzeniek Z; Tsai CM; Ginburg V -
Carbohydrate antigens: coupling of oligosaccharide phenethylamine-isothiocyanate derivatives to bovine serum albumin.
Methods Enzymol Volume: 50 Page(s): 169 - 171
01/01/1978 Authors: Smith DF; Zopf DA; Ginsburg V -
Sialyl oligosaccharides from milk.
Methods Enzymol Volume: 50 Page(s): 221 - 226
01/01/1978 Authors: Smith DF; Zopf DA; Ginsburg V -
Comparative chemical analyses and partial amino acid sequences of the heavy chains of HL-A antigens.
Cold Spring Harb Symp Quant Biol Volume: 41 Pt 1 Page(s): 341 - 342
01/01/1977 Authors: Appella E; Tanigaki N; Henriksen O; Pressman D; Smith DF; Fairwell T -
Comparative chemical analyses of the alloantigenic fragments of HL-A antigens.
J Biol Chem Volume: 251 Page(s): 4214 - 4219
07/25/1976 Authors: Henriksen O; Appella E; Smith DF; Tanigaki N; Pressman D -
Chemical characterization of a mouse immunoglobulin A heavy chain with a 100-residue deletion. Amino acid and carbohydrate compositions and NH2-and COOH-terminal sequences.
J Biol Chem Volume: 249 Page(s): 6605 - 6610
10/25/1974 Authors: Robinson EA; Smith DF; Appella E