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Profile

Dale Edmondson PhD

  • Department of Biochemistry
    Professor Emeritus
  • (404) 727-5972
  • deedmon@emory.edu

Academic Appointment

  • Adjunct Professor of Chemistry, Emory University School of Medicine
  • Professor, Department of Biochemistry, Emory University School of Medicine
  • Professor of Biochemistry, Emory University School of Medicine

Education

Degrees

  • PhD from University of Arizona
  • BS from Northern Illinois University

Research

Focus

  • Flavin chemistry and flavoenzyme catalysis, mechanism of action of molybdoenzymes, dinuclear iron structure and function.

Publications

  • Crystallization of Human Monoamine Oxidase B.
    Methods Mol Biol Volume: 2558 Page(s): 115 - 122
    01/01/2023 Authors: Binda C; Edmondson DE; Mattevi A
  • Purification of Recombinant Eukaryotic MAO A and MAO B Utilizing the Pichia pastoris Expression System.
    Methods Mol Biol Volume: 2558 Page(s): 11 - 22
    01/01/2023 Authors: Edmondson DE
  • Purification of MAO A and MAO B from Mammalian Tissue Sources.
    Methods Mol Biol Volume: 2558 Page(s): 1 - 10
    01/01/2023 Authors: Edmondson DE
  • Rational Redesign of Monoamine Oxidase A into a Dehydrogenase to Probe ROS in Cardiac Aging.
    ACS Chem Biol Volume: 15 Page(s): 1795 - 1800
    07/17/2020 Authors: Iacovino LG; Manzella N; Resta J; Vanoni MA; Rotilio L; Pisani L; Edmondson DE; Parini A; Mattevi A; Mialet-Perez J
  • Monoamine Oxidases.
    Subcell Biochem Volume: 87 Page(s): 117 - 139
    01/01/2018 Authors: Edmondson DE; Binda C
  • Biosensor for the characterisation of hMAO B inhibitors and the quantification of selegiline.
    Talanta Volume: 174 Page(s): 696 - 702
    11/01/2017 Authors: Aigner M; Preissegger P; Kalcher K; Mehmeti E; Macheroux P; Edmondson D; Ortner A
  • Monoamine Oxidases, Oxidative Stress, and Altered Mitochondrial Dynamics in Cardiac Ageing.
    Oxid Med Cell Longev Volume: 2017 Page(s): 3017947
    01/01/2017 Authors: Maggiorani D; Manzella N; Edmondson DE; Mattevi A; Parini A; Binda C; Mialet-Perez J
  • Design and synthesis of novel chalcones as potent selective monoamine oxidase-B inhibitors.
    Eur J Med Chem Volume: 114 Page(s): 162 - 169
    05/23/2016 Authors: Hammuda A; Shalaby R; Rovida S; Edmondson DE; Binda C; Khalil A
  • Why p-OMe- and p-Cl--Methylphenethylamines Display Distinct Activities upon MAO-B Binding.
    PLoS One Volume: 11 Page(s): e0154989
    01/01/2016 Authors: Fierro A; Edmondson DE; Celis-Barros C; Rebolledo-Fuentes M; Zapata-Torres G
  • Reversible and irreversible small molecule inhibitors of monoamine oxidase B (MAO-B) investigated by biophysical techniques.
    Bioorg Med Chem Volume: 23 Page(s): 770 - 778
    02/15/2015 Authors: Rojas RJ; Edmondson DE; Almos T; Scott R; Massari ME
  • Hydrogen peroxide produced by mitochondrial monoamine oxidase catalysis: biological implications.
    Curr Pharm Des Volume: 20 Page(s): 155 - 160
    01/01/2014 Authors: Edmondson DE
  • Truncated FAD synthetase for direct biocatalytic conversion of riboflavin and analogs to their corresponding flavin mononucleotides.
    Protein Eng Des Sel Volume: 26 Page(s): 791 - 795
    12/01/2013 Authors: Iamurri SM; Daugherty AB; Edmondson DE; Lutz S
  • Do MAO A and MAO B utilize the same mechanism for the C-H bond cleavage step in catalysis? Evidence suggesting differing mechanisms.
    J Neural Transm (Vienna) Volume: 120 Page(s): 847 - 851
    06/01/2013 Authors: Orru R; Aldeco M; Edmondson DE
  • Mirroring human monoamine oxidases A and B: Similar structures with opposite mechanisms of C-H bond cleavage
    Volume: 27
    04/01/2013 Authors: Orru R; Aldeco M; Edmondson DE
  • Beyond the Protein Matrix: Probing Cofactor Variants in a Baeyer-Villiger Oxygenation Reaction.
    ACS Catal Volume: 3 Page(s): 3058 - 3062
    01/01/2013 Authors: Martinoli C; Dudek HM; Orru R; Edmondson DE; Fraaije MW; Mattevi A
  • Precursor of ether phospholipids is synthesized by a flavoenzyme through covalent catalysis.
    Proc Natl Acad Sci U S A Volume: 109 Page(s): 18791 - 18796
    11/13/2012 Authors: Nenci S; Piano V; Rosati S; Aliverti A; Pandini V; Fraaije MW; Heck AJR; Edmondson DE; Mattevi A
  • Structural basis for benzothiazinone-mediated killing of Mycobacterium tuberculosis.
    Sci Transl Med Volume: 4 Page(s): 150ra121
    09/05/2012 Authors: Neres J; Pojer F; Molteni E; Chiarelli LR; Dhar N; Boy-Rttger S; Buroni S; Fullam E; Degiacomi G; Lucarelli AP
  • The 'gating' residues Ile199 and Tyr326 in human monoamine oxidase B function in substrate and inhibitor recognition.
    FEBS J Volume: 278 Page(s): 4860 - 4869
    12/01/2011 Authors: Milczek EM; Binda C; Rovida S; Mattevi A; Edmondson DE
  • Lights and shadows on monoamine oxidase inhibition in neuroprotective pharmacological therapies.
    Curr Top Med Chem Volume: 11 Page(s): 2788 - 2796
    11/01/2011 Authors: Binda C; Milczek EM; Bonivento D; Wang J; Mattevi A; Edmondson DE
  • Molecular Insights into Human Monoamine Oxidase B Inhibition by the Glitazone Anti-Diabetes Drugs.
    ACS Med Chem Lett Volume: 3 Page(s): 39 - 42
    10/15/2011 Authors: Binda C; Aldeco M; Geldenhuys WJ; Tortorici M; Mattevi A; Edmondson DE
  • H kinetic isotope effects and pH dependence of catalysis as mechanistic probes of rat monoamine oxidase A: comparisons with the human enzyme.
    Biochemistry Volume: 50 Page(s): 7710 - 7717
    09/06/2011 Authors: Wang J; Edmondson DE
  • Nitrogen kinetic isotope effects for the monoamine oxidase B-catalyzed oxidation of benzylamine and (1,1-(2)H2)benzylamine: nitrogen rehybridization and CH bond cleavage are not concerted.
    J Am Chem Soc Volume: 133 Page(s): 12319 - 12321
    08/17/2011 Authors: MacMillar S; Edmondson DE; Matsson O
  • Catalytic and inhibitor binding properties of zebrafish monoamine oxidase (zMAO): comparisons with human MAO A and MAO B.
    Comp Biochem Physiol B Biochem Mol Biol Volume: 159 Page(s): 78 - 83
    06/01/2011 Authors: Aldeco M; Arslan BK; Edmondson DE
  • Topological probes of monoamine oxidases A and B in rat liver mitochondria: inhibition by TEMPO-substituted pargyline analogues and inactivation by proteolysis.
    Biochemistry Volume: 50 Page(s): 2499 - 2505
    04/05/2011 Authors: Wang J; Edmondson DE
  • Interactions of monoamine oxidases with the antiepileptic drug zonisamide: specificity of inhibition and structure of the human monoamine oxidase B complex.
    J Med Chem Volume: 54 Page(s): 909 - 912
    02/10/2011 Authors: Binda C; Aldeco M; Mattevi A; Edmondson DE
  • Structural properties of human monoamine oxidases A and B.
    Int Rev Neurobiol Volume: 100 Page(s): 1 - 11
    01/01/2011 Authors: Binda C; Mattevi A; Edmondson DE
  • Potentiation of ligand binding through cooperative effects in monoamine oxidase B.
    J Biol Chem Volume: 285 Page(s): 36849 - 36856
    11/19/2010 Authors: Bonivento D; Milczek EM; McDonald GR; Binda C; Holt A; Edmondson DE; Mattevi A
  • Biochemical, structural, and biological evaluation of tranylcypromine derivatives as inhibitors of histone demethylases LSD1 and LSD2.
    J Am Chem Soc Volume: 132 Page(s): 6827 - 6833
    05/19/2010 Authors: Binda C; Valente S; Romanenghi M; Pilotto S; Cirilli R; Karytinos A; Ciossani G; Botrugno OA; Forneris F; Tardugno M
  • High-level expression and purification of rat monoamine oxidase A (MAO A) in Pichia pastoris: comparison with human MAO A.
    Protein Expr Purif Volume: 70 Page(s): 211 - 217
    04/01/2010 Authors: Wang J; Edmondson DE
  • Expression of zebrafish (Danio rerio) monoamine oxidase (MAO) in Pichia pastoris: purification and comparison with human MAO A and MAO B.
    Protein Expr Purif Volume: 70 Page(s): 290 - 297
    04/01/2010 Authors: Arslan BK; Edmondson DE
  • 2-Arylthiomorpholine derivatives as potent and selective monoamine oxidase B inhibitors.
    Bioorg Med Chem Volume: 18 Page(s): 1388 - 1395
    02/15/2010 Authors: Lhr S; Vilches-Herrera M; Fierro A; Ramsay RR; Edmondson DE; Reyes-Parada M; Cassels BK; Iturriaga-Vsquez P
  • Dual role of FMN in flavodoxin function: electron transfer cofactor and modulation of the protein-protein interaction surface.
    Biochim Biophys Acta Volume: 1797 Page(s): 262 - 271
    02/01/2010 Authors: Frago S; Lans I; Navarro JA; Hervs M; Edmondson DE; De la Rosa MA; Gmez-Moreno C; Mayhew SG; Medina M
  • Serine 209 resides within a putative p38(MAPK) consensus motif and regulates monoamine oxidase-A activity.
    J Neurochem Volume: 111 Page(s): 101 - 110
    10/01/2009 Authors: Cao X; Rui L; Pennington PR; Chlan-Fourney J; Jiang Z; Wei Z; Li X-M; Edmondson DE; Mousseau DD
  • Mutagenic probes of the role of Ser209 on the cavity shaping loop of human monoamine oxidase A.
    FEBS J Volume: 276 Page(s): 4569 - 4581
    08/01/2009 Authors: Wang J; Harris J; Mousseau DD; Edmondson DE
  • Molecular and mechanistic properties of the membrane-bound mitochondrial monoamine oxidases.
    Biochemistry Volume: 48 Page(s): 4220 - 4230
    05/26/2009 Authors: Edmondson DE; Binda C; Wang J; Upadhyay AK; Mattevi A
  • Development of spin-labeled pargyline analogues as specific inhibitors of human monoamine oxidases A and B.
    Biochemistry Volume: 48 Page(s): 3928 - 3935
    05/12/2009 Authors: Upadhyay AK; Edmondson DE
  • Inhibition of monoamine oxidase by (E)-styrylisatin analogues.
    Bioorg Med Chem Lett Volume: 19 Page(s): 2509 - 2513
    05/01/2009 Authors: Van der Walt EM; Milczek EM; Malan SF; Edmondson DE; Castagnoli N; Bergh JJ; Petzer JP
  • Structural and mechanistic studies of mofegiline inhibition of recombinant human monoamine oxidase B.
    J Med Chem Volume: 51 Page(s): 8019 - 8026
    12/25/2008 Authors: Milczek EM; Bonivento D; Binda C; Mattevi A; McDonald IA; Edmondson DE
  • Bioactive contaminants leach from disposable laboratory plasticware.
    Science Volume: 322 Page(s): 917
    11/07/2008 Authors: McDonald GR; Hudson AL; Dunn SMJ; You H; Baker GB; Whittal RM; Martin JW; Jha A; Edmondson DE; Holt A
  • Characterization of detergent purified recombinant rat liver monoamine oxidase B expressed in Pichia pastoris.
    Protein Expr Purif Volume: 59 Page(s): 349 - 356
    06/01/2008 Authors: Upadhyay AK; Edmondson DE
  • Structural and mechanistic studies of arylalkylhydrazine inhibition of human monoamine oxidases A and B.
    Biochemistry Volume: 47 Page(s): 5616 - 5625
    05/20/2008 Authors: Binda C; Wang J; Li M; Hubalek F; Mattevi A; Edmondson DE
  • Stereochemical studies on the novel monoamine oxidase B substrates (1R,6S)- and (1S,6R)-3-methyl-6-phenyl-3-aza-bicyclo[4.1.0]heptane.
    Bioorg Med Chem Volume: 16 Page(s): 3557 - 3564
    04/01/2008 Authors: Bissel P; Khalil A; Rimoldi JM; Igarashi K; Edmondson D; Miller A; Castagnoli N
  • Determination of the oligomeric states of human and rat monoamine oxidases in the outer mitochondrial membrane and octyl beta-D-glucopyranoside micelles using pulsed dipolar electron spin resonance spectroscopy.
    Biochemistry Volume: 47 Page(s): 1554 - 1566
    02/12/2008 Authors: Upadhyay AK; Borbat PP; Wang J; Freed JH; Edmondson DE
  • Comparison of the structural properties of the active site cavities of human and rat monoamine oxidase A and B in their soluble and membrane-bound forms.
    Biochemistry Volume: 47 Page(s): 526 - 536
    01/15/2008 Authors: Upadhyay AK; Wang J; Edmondson DE
  • AZOTOBACTER VINELANDII NITROGENASE MoFe PROTEIN: PRE-STEADY STATE SPECTROSCOPIC STUDIES OF THE METAL COFACTORS
    Volume: 42 Page(s): 331 - 333
    01/01/2008 Authors: Newton WE; Fisher K; Huynh BH; Edmondson DE; Tavares P; Pereira AS; Lowe DJ
  • Monoamine oxidases and LSD1: Similar chemistry for neurotransmitter and chromatin modification
    Volume: 64 Page(s): C37 - C38
    01/01/2008 Authors: Mattevi A; Forneris F; Edmondson DE; Binda C
  • Structures of human monoamine oxidase B complexes with selective noncovalent inhibitors: safinamide and coumarin analogs.
    J Med Chem Volume: 50 Page(s): 5848 - 5852
    11/15/2007 Authors: Binda C; Wang J; Pisani L; Caccia C; Carotti A; Salvati P; Edmondson DE; Mattevi A
  • Conformations generated during turnover of the Azotobacter vinelandii nitrogenase MoFe protein and their relationship to physiological function.
    J Inorg Biochem Volume: 101 Page(s): 1649 - 1656
    11/01/2007 Authors: Fisher K; Lowe DJ; Tavares P; Pereira AS; Huynh BH; Edmondson D; Newton WE
  • Structural insights into the mechanism of amine oxidation by monoamine oxidases A and B.
    Arch Biochem Biophys Volume: 464 Page(s): 269 - 276
    08/15/2007 Authors: Edmondson DE; Binda C; Mattevi A
  • Human and rat monoamine oxidase-A are differentially inhibited by (S)-4-alkylthioamphetamine derivatives: insights from molecular modeling studies.
    Bioorg Med Chem Volume: 15 Page(s): 5198 - 5206
    08/01/2007 Authors: Fierro A; Osorio-Olivares M; Cassels BK; Edmondson DE; Seplveda-Boza S; Reyes-Parada M
  • Plasmalogen assembly: a key flavoenzyme.
    Structure Volume: 15 Page(s): 639 - 641
    06/01/2007 Authors: Edmondson DE
  • Do monomeric vs dimeric forms of MAO-A make a difference? A direct comparison of the catalytic properties of rat and human MAO-A's.
    J Neural Transm (Vienna) Volume: 114 Page(s): 721 - 724
    01/01/2007 Authors: Wang J; Edmondson DE
  • New insights into the structures and functions of human monoamine oxidases A and B.
    J Neural Transm (Vienna) Volume: 114 Page(s): 703 - 705
    01/01/2007 Authors: Edmondson DE; DeColibus L; Binda C; Li M; Mattevi A
  • Kinetic properties of recombinant MAO-A on incorporation into phospholipid nanodisks.
    J Neural Transm (Vienna) Volume: 114 Page(s): 699 - 702
    01/01/2007 Authors: Cruz F; Edmondson DE
  • The aromatic cage in the active site of monoamine oxidase B: effect on the structural and electronic properties of bound benzylamine and p-nitrobenzylamine.
    J Neural Transm (Vienna) Volume: 114 Page(s): 693 - 698
    01/01/2007 Authors: Akyz MA; Erdem SS; Edmondson DE
  • Functional role of the "aromatic cage" in human monoamine oxidase B: structures and catalytic properties of Tyr435 mutant proteins.
    Biochemistry Volume: 45 Page(s): 4775 - 4784
    04/18/2006 Authors: Li M; Binda C; Mattevi A; Edmondson DE
  • The therapeutic potential of monoamine oxidase inhibitors.
    Nat Rev Neurosci Volume: 7 Page(s): 295 - 309
    04/01/2006 Authors: Youdim MBH; Edmondson D; Tipton KF
  • Studies on the role of lysine-296 in human mitochondrial monoamine oxidase B catalysis
    Volume: 20 Page(s): A478 - A479
    03/06/2006 Authors: Kacar B; Edmondson DE
  • Binding of rasagiline-related inhibitors to human monoamine oxidases: a kinetic and crystallographic analysis.
    J Med Chem Volume: 48 Page(s): 8148 - 8154
    12/29/2005 Authors: Binda C; Hublek F; Li M; Herzig Y; Sterling J; Edmondson DE; Mattevi A
  • Three-dimensional structure of human monoamine oxidase A (MAO A): relation to the structures of rat MAO A and human MAO B.
    Proc Natl Acad Sci U S A Volume: 102 Page(s): 12684 - 12689
    09/06/2005 Authors: De Colibus L; Li M; Binda C; Lustig A; Edmondson DE; Mattevi A
  • Demonstration of isoleucine 199 as a structural determinant for the selective inhibition of human monoamine oxidase B by specific reversible inhibitors.
    J Biol Chem Volume: 280 Page(s): 15761 - 15766
    04/22/2005 Authors: Hublek F; Binda C; Khalil A; Li M; Mattevi A; Castagnoli N; Edmondson DE
  • Oxygen isotope effects on electron transfer to O-2 probed using chemically modified flavins bound to glucose oxidase
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY Volume: 127 Page(s): 5727 - 5727
    04/20/2005 Authors: Roth JP; Wincek R; Nodet G; Edmondson DE; McIntire WS; Klinman JP
  • Oxygen isotope effects on electron transfer to O2 probed using chemically modified flavins bound to glucose oxidase.
    J Am Chem Soc Volume: 126 Page(s): 15120 - 15131
    11/24/2004 Authors: Roth JP; Wincek R; Nodet G; Edmondson DE; McIntire WS; Klinman JP
  • High-level expression and characterization of a highly functional Comamonas acidovorans xanthine dehydrogenase in Pseudomonas aeruginosa.
    Protein Expr Purif Volume: 37 Page(s): 72 - 82
    09/01/2004 Authors: Ivanov NV; Trani M; Edmondson DE
  • Structure and mechanism of monoamine oxidase.
    Curr Med Chem Volume: 11 Page(s): 1983 - 1993
    08/01/2004 Authors: Edmondson DE; Mattevi A; Binda C; Li M; Hublek F
  • Crystal structure of human monoamine oxidase B, a drug target enzyme monotopically inserted into the mitochondrial outer membrane.
    FEBS Lett Volume: 564 Page(s): 225 - 228
    04/30/2004 Authors: Binda C; Hublek F; Li M; Edmondson DE; Mattevi A
  • Inactivation of purified human recombinant monoamine oxidases A and B by rasagiline and its analogues.
    J Med Chem Volume: 47 Page(s): 1760 - 1766
    03/25/2004 Authors: Hublek F; Binda C; Li M; Herzig Y; Sterling J; Youdim MBH; Mattevi A; Edmondson DE
  • Crystal structures of monoamine oxidase B in complex with four inhibitors of the N-propargylaminoindan class.
    J Med Chem Volume: 47 Page(s): 1767 - 1774
    03/25/2004 Authors: Binda C; Hublek F; Li M; Herzig Y; Sterling J; Edmondson DE; Mattevi A
  • The FAD binding sites of human monoamine oxidases A and B.
    Neurotoxicology Volume: 25 Page(s): 63 - 72
    01/01/2004 Authors: Edmondson DE; Binda C; Mattevi A
  • Structure of the human outer-mitochondrial membrane Monoamine Oxidase B at 1.7 angstrom resolution
    Volume: 60 Page(s): S22 - S22
    01/01/2004 Authors: Mattevi A; Li M; Hubalek F; Edmondson DE; Binda C
  • Factors involved in the assembly of a functional molybdopyranopterin center in recombinant Comamonas acidovorans xanthine dehydrogenase.
    Eur J Biochem Volume: 270 Page(s): 4744 - 4754
    12/01/2003 Authors: Ivanov NV; Hublek F; Trani M; Edmondson DE
  • Ability of tetrahydrobiopterin analogues to support catalysis by inducible nitric oxide synthase: formation of a pterin radical is required for enzyme activity.
    Biochemistry Volume: 42 Page(s): 13287 - 13303
    11/18/2003 Authors: Hurshman AR; Krebs C; Edmondson DE; Marletta MA
  • Polystyrene microbridges used in sitting-drop crystallization release 1,4-diphenyl-2-butene, a novel inhibitor of human MAO B.
    Acta Crystallogr D Biol Crystallogr Volume: 59 Page(s): 1874 - 1876
    10/01/2003 Authors: Hublek F; Binda C; Li M; Mattevi A; Edmondson DE
  • Insights into the mode of inhibition of human mitochondrial monoamine oxidase B from high-resolution crystal structures.
    Proc Natl Acad Sci U S A Volume: 100 Page(s): 9750 - 9755
    08/19/2003 Authors: Binda C; Li M; Hubalek F; Restelli N; Edmondson DE; Mattevi A
  • Structural comparison of human monoamine oxidases A and B: mass spectrometry monitoring of cysteine reactivities.
    J Biol Chem Volume: 278 Page(s): 28612 - 28618
    08/01/2003 Authors: Hubalek F; Pohl J; Edmondson DE
  • Structure-function relationships in flavoenzyme-dependent amine oxidations: a comparison of polyamine oxidase and monoamine oxidase.
    J Biol Chem Volume: 277 Page(s): 23973 - 23976
    07/05/2002 Authors: Binda C; Mattevi A; Edmondson DE
  • Synthesis and characterization of a collagen model delta-O-phosphohydroxylysine-containing peptide.
    Anal Biochem Volume: 306 Page(s): 124 - 134
    07/01/2002 Authors: Hublek F; Edmondson DE; Pohl J
  • Phentermine inhibition of recombinant human liver monoamine oxidases A and B.
    Biochem Pharmacol Volume: 63 Page(s): 865 - 869
    03/01/2002 Authors: Nandigama RK; Newton-Vinson P; Edmondson DE
  • High-level expression of human liver monoamine oxidase A in Pichia pastoris: comparison with the enzyme expressed in Saccharomyces cerevisiae.
    Protein Expr Purif Volume: 24 Page(s): 152 - 162
    02/01/2002 Authors: Li M; Hublek F; Newton-Vinson P; Edmondson DE
  • Structure of human monoamine oxidase B, a drug target for the treatment of neurological disorders.
    Nat Struct Biol Volume: 9 Page(s): 22 - 26
    01/01/2002 Authors: Binda C; Newton-Vinson P; Hublek F; Edmondson DE; Mattevi A
  • STRUCTURE OF HUMAN MONOAMINE OXIDASE B, A DRUG TARGET FOR NEUROLOGICAL DISORDERS
    Volume: 58 Page(s): C246 - C246
    01/01/2002 Authors: Mattevi A; Edmondson DE; Binda C
  • Demonstration of peroxodiferric intermediate in M-ferritin ferroxidase reaction using rapid freeze-quench Mssbauer, resonance Raman, and XAS spectroscopies.
    Methods Enzymol Volume: 354 Page(s): 436 - 454
    01/01/2002 Authors: Krebs C; Edmondson DE; Huynh BH
  • Loss of serotonin oxidation as a component of the altered substrate specificity in the Y444F mutant of recombinant human liver MAO A.
    Biochemistry Volume: 40 Page(s): 14839 - 14846
    12/11/2001 Authors: Nandigama RK; Miller JR; Edmondson DE
  • The covalent FAD of monoamine oxidase: structural and functional role and mechanism of the flavinylation reaction.
    Antioxid Redox Signal Volume: 3 Page(s): 789 - 806
    10/01/2001 Authors: Edmondson DE; Newton-Vinson P
  • Properties of C-terminal truncated mutants of monoamine oxidase B
    Volume: 15 Page(s): A524 - A524
    03/07/2001 Authors: Newton-Vinson P; Edmondson DE
  • Structure-activity relations in the oxidation of phenethylamine analogues by recombinant human liver monoamine oxidase A.
    Biochemistry Volume: 39 Page(s): 15258 - 15265
    12/12/2000 Authors: Nandigama RK; Edmondson DE
  • High-level expression of human liver monoamine oxidase B in Pichia pastoris.
    Protein Expr Purif Volume: 20 Page(s): 334 - 345
    11/01/2000 Authors: Newton-Vinson P; Hubalek F; Edmondson DE
  • Influence of FAD structure on its binding and activity with the C406A mutant of recombinant human liver monoamine oxidase A.
    J Biol Chem Volume: 275 Page(s): 20527 - 20532
    07/07/2000 Authors: Nandigama RK; Edmondson DE
  • Evidence for alternative binding modes in the interaction of benzylamine analogues with bovine liver monoamine oxidase B.
    Biochim Biophys Acta Volume: 1479 Page(s): 52 - 58
    06/15/2000 Authors: Edmondson DE; Bhattacharrya AK; Xu J
  • Evidence for alternative binding modes in the interaction of benzylamine analogs with bovine liver monoamine oxidase B (MAOB).
    Volume: 14 Page(s): A1416 - A1416
    05/11/2000 Authors: Bhattacharyya AK; Edmondson DE; Xu JJ
  • A short Fe-Fe distance in peroxodiferric ferritin: control of Fe substrate versus cofactor decay?
    Science Volume: 287 Page(s): 122 - 125
    01/07/2000 Authors: Hwang J; Krebs C; Huynh BH; Edmondson DE; Theil EC; Penner-Hahn JE
  • The FAD binding sites of human liver monoamine oxidases A and B: investigation of the role of flavin ribityl side chain hydroxyl groups in the covalent flavinylation reaction and catalytic activities.
    Biochim Biophys Acta Volume: 1476 Page(s): 27 - 32
    01/03/2000 Authors: Miller JR; Guan N; Hubalek F; Edmondson DE
  • Formation of a pterin radical in the reaction of the heme domain of inducible nitric oxide synthase with oxygen.
    Biochemistry Volume: 38 Page(s): 15689 - 15696
    11/30/1999 Authors: Hurshman AR; Krebs C; Edmondson DE; Huynh BH; Marletta MA
  • Structure-activity relationships in the oxidation of para-substituted benzylamine analogues by recombinant human liver monoamine oxidase A.
    Biochemistry Volume: 38 Page(s): 13670 - 13683
    10/12/1999 Authors: Miller JR; Edmondson DE
  • Influence of flavin analogue structure on the catalytic activities and flavinylation reactions of recombinant human liver monoamine oxidases A and B.
    J Biol Chem Volume: 274 Page(s): 23515 - 23525
    08/13/1999 Authors: Miller JR; Edmondson DE
  • Rapid freeze-quench mossbauer investigations of intermediates in oxygen activation reactions of carboxylate-bridged diiron proteins
    Volume: 74 Page(s): 33 - 33
    04/30/1999 Authors: Krebs C; Edmondson DE; Huynh BH
  • Mossbauer and EPR spectroscopic evidence for spin-coupled X-protein radical intermediates during oxygen activation of ribonucleotide reductase R2 protein from E-coli
    Volume: 74 Page(s): 195 - 195
    04/30/1999 Authors: Krebs C; Baldwin J; Chen S; Ley BA; Edmondson DE; Bollinger JM; Huynh BH
  • Rational engineering of the R2 subunit of Escherichia coli ribonucleotide reductase into a self-hydroxylating monooxygenase
    Volume: 74 Page(s): 74 - 74
    04/30/1999 Authors: Baldwin J; Moenne-Loccoz P; Krebs C; Ley BA; Edmondson DE; Huynh BH; Loehr TM; Bollinger JM
  • Structural determinants of the mechanisms and outcomes of O-2 activation by the diiron carboxylate proteins
    Volume: 74 Page(s): 13 - 13
    04/30/1999 Authors: Bollinger JM; Baldwin J; Krebs C; Chen S; Ley BA; Edmondson DE; Huynh BH
  • The ferroxidase reaction of ferritin reveals a diferric mu-1,2 bridging peroxide intermediate in common with other O2-activating non-heme diiron proteins.
    Biochemistry Volume: 38 Page(s): 5290 - 5295
    04/27/1999 Authors: Monne-Loccoz P; Krebs C; Herlihy K; Edmondson DE; Theil EC; Huynh BH; Loehr TM
  • Influence of isoalloxazine modification on the activity of human liver monoamine oxidase a C406A mutant expressed in Saccharomyces cerevisiae.
    Volume: 13 Page(s): A1436 - A1436
    04/23/1999 Authors: Nandigama RK; Edmondson DE
  • Expression, purification, and characterization of human liver MAO B from Pichia pastoris
    Volume: 13 Page(s): A1437 - A1437
    04/23/1999 Authors: Newton-Vinson AP; Edmondson DE
  • Benzylamine analog binding studies as probes of the substrate sites of monoamine oxidases A and B.
    Drug Metab Rev Volume: 31 Page(s): 235 - 245
    02/01/1999 Authors: Edmondson DE
  • Flavoenzyme structure and function. Approaches using flavin analogues.
    Methods Mol Biol Volume: 131 Page(s): 157 - 179
    01/01/1999 Authors: Edmondson D; Ghisla S
  • Direct spectroscopic and kinetic evidence for the involvement of a peroxodiferric intermediate during the ferroxidase reaction in fast ferritin mineralization.
    Biochemistry Volume: 37 Page(s): 9871 - 9876
    07/14/1998 Authors: Pereira AS; Small W; Krebs C; Tavares P; Edmondson DE; Theil EC; Huynh BH
  • Characterization of Y122F R2 of Escherichia coli ribonucleotide reductase by time-resolved physical biochemical methods and X-ray crystallography.
    Biochemistry Volume: 37 Page(s): 5840 - 5848
    04/28/1998 Authors: Tong W; Burdi D; Riggs-Gelasco P; Chen S; Edmondson D; Huynh BH; Stubbe J; Han S; Arvai A; Tainer J
  • Reaction of Escherichia coli cytochrome bo3 with substoichiometric ubiquinol-2: a freeze-quench electron paramagnetic resonance investigation.
    Biochemistry Volume: 37 Page(s): 4160 - 4168
    03/24/1998 Authors: Schultz BE; Edmondson DE; Chan SI
  • The recombinant alpha subunit of glutamate synthase: spectroscopic and catalytic properties.
    Biochemistry Volume: 37 Page(s): 1828 - 1838
    02/17/1998 Authors: Vanoni MA; Fischer F; Ravasio S; Verzotti E; Edmondson DE; Hagen WR; Zanetti G; Curti B
  • Electron injection through a specific pathway determines the outcome of oxygen activation at the diiron cluster in the F208Y mutant of Escherichia coli ribonucleotide reductase protein R2.
    Biochemistry Volume: 37 Page(s): 1124 - 1130
    01/27/1998 Authors: Parkin SE; Chen S; Ley BA; Mangravite L; Edmondson DE; Huynh BH; Bollinger JM
  • Rapid formation of a semiquinone species on oxidation of quinol by the cytochrome bo(3) oxidase from Escherichia coli
    Volume: 1 Page(s): 33 - 39
    01/01/1998 Authors: Osborne JP; Musser SM; Schultz BE; Edmondson DE; Chan SI; Gennis RB
  • Characterization of a diiron(III) peroxo intermediate in the reaction cycle of methane monooxygenase hydroxylase from Methylococcus capsulatus (Bath) (vol 117, pg 4997, 1995)
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY Volume: 119 Page(s): 11134 - 11134
    11/12/1997 Authors: Liu KE; Valentine AM; Qiu D; Edmondson DE; Appelman EH; Spiro TG; Lippard SJ
  • Rapid and parallel formation of Fe3+ multimers, including a trimer, during H-type subunit ferritin mineralization.
    Biochemistry Volume: 36 Page(s): 7917 - 7927
    06/24/1997 Authors: Pereira AS; Tavares P; Lloyd SG; Danger D; Edmondson DE; Theil EC; Huynh BH
  • Mossbauer spectroscopic and kinetic characterization of ferric clusters formed in h-chain ferritin mineralization.
    Volume: 213 Page(s): 503 - INOR
    04/13/1997 Authors: Tavares P; Pereira AS; Lloyd SG; Danger D; Edmondson DE; Theil EC; Huynh BH
  • From the mass production of Methylococcus capsulatus to the efficient separation and isolation of methane monooxygenase proteins. Characterization of novel intermediates in substrate reactions of methane monooxygenase.
    Volume: 26 Page(s): 273 - 286
    01/01/1997 Authors: Liu KE; Valentine AM; Wang DL; Huynh BH; Edmondson DE; Salifoglou A; Lippard SJ
  • Purification and characterization of a prokaryotic xanthine dehydrogenase from Comamonas acidovorans.
    Biochemistry Volume: 35 Page(s): 5441 - 5450
    04/30/1996 Authors: Xiang Q; Edmondson DE
  • Sarcosine oxidase contains a novel covalently bound FMN.
    Biochemistry Volume: 35 Page(s): 5292 - 5299
    04/23/1996 Authors: Willie A; Edmondson DE; Jorns MS
  • Aminium cation radical mechanism proposed for monoamine oxidase B catalysis: are there alternatives?
    Xenobiotica Volume: 25 Page(s): 735 - 753
    07/01/1995 Authors: Edmondson DE
  • SEQUENCE SIMILARITIES OF PSEUDOMONAS ACIDOVORANS XANTHINE DEHYDROGENASE WITH THOSE FROM EUKARYOTES
    Volume: 9 Page(s): A1358 - A1358
    04/24/1995 Authors: XIANG Q; EDMONDSON DE
  • Structure activity studies of the substrate binding site in monoamine oxidase B.
    Biochimie Volume: 77 Page(s): 643 - 650
    01/01/1995 Authors: Edmondson DE
  • Use of rapid kinetics methods to study the assembly of the diferric-tyrosyl radical cofactor of E. coli ribonucleotide reductase.
    Methods Enzymol Volume: 258 Page(s): 278 - 303
    01/01/1995 Authors: Bollinger JM; Tong WH; Ravi N; Huynh BH; Edmondson DE; Stubbe JA
  • Hydrogen tunneling in the flavoenzyme monoamine oxidase B.
    Biochemistry Volume: 33 Page(s): 14871 - 14878
    12/13/1994 Authors: Jonsson T; Edmondson DE; Klinman JP
  • Flavin substrate specificity of the vitamin B2-aldehyde-forming enzyme from Schizophyllum commune.
    Arch Biochem Biophys Volume: 315 Page(s): 100 - 103
    11/15/1994 Authors: Kekelidze TN; Edmondson DE; McCormick DB
  • Kinetic studies on the electron-transfer reaction between cytochrome c3 and flavodoxin from Desulfovibrio vulgaris strain Hildenborough.
    Biochemistry Volume: 33 Page(s): 10386 - 10392
    08/30/1994 Authors: De Francesco R; Edmondson DE; Moura I; Moura JJ; LeGall J
  • Structure-activity relationships in the oxidation of benzylamine analogues by bovine liver mitochondrial monoamine oxidase B.
    Biochemistry Volume: 33 Page(s): 7088 - 7098
    06/14/1994 Authors: Walker MC; Edmondson DE
  • FLAVIN SPECIFICITY OF THE VITAMIN-B(2)-ALDEHYDE FORMING ENZYME IN SCHIZOPHYLLUM-COMMUNE
    Volume: 8 Page(s): A1422 - A1422
    04/19/1994 Authors: KEKELIDZE TN; EDMONDSON DE; MCCORMICK DB
  • PURIFICATION AND PROPERTIES OF XANTHINE DEHYDROGENASE FROM PSEUDOMONAS-ACIDOVORANS
    Volume: 8 Page(s): A1422 - A1422
    04/19/1994 Authors: XIANG O; EDMONDSON DE
  • Quantitative structure-activity relationships in the oxidation of benzylamine analogues by bovine liver monoamine oxidase B
    Page(s): 109 - 115
    01/01/1994 Authors: Walker MC; Edmondson DE
  • Studies on the induction and phosphorylation of xanthine dehydrogenase in cultured chick embryo hepatocytes.
    Eur J Biochem Volume: 215 Page(s): 307 - 314
    07/15/1993 Authors: Schieber A; Edmondson DE
  • Spectral and kinetic studies of imine product formation in the oxidation of p-(N,N-dimethylamino)benzylamine analogues by monoamine oxidase B.
    Biochemistry Volume: 32 Page(s): 5196 - 5202
    05/18/1993 Authors: Edmondson DE; Bhattacharyya AK; Walker MC
  • Resonance Raman spectroscopic evidence for an anionic flavin semiquinone in bovine liver monoamine oxidase.
    Arch Biochem Biophys Volume: 300 Page(s): 178 - 185
    01/01/1993 Authors: Yue KT; Bhattacharyya AK; Zhelyaskov VR; Edmondson DE
  • Role of phospholipase D-derived diradylglycerol in the activation of the human neutrophil respiratory burst oxidase. Inhibition by phosphatidic acid phosphohydrolase inhibitors.
    J Immunol Volume: 149 Page(s): 2749 - 2758
    10/15/1992 Authors: Perry DK; Hand WL; Edmondson DE; Lambeth JD
  • Characterization of the flavins and the iron-sulfur centers of glutamate synthase from Azospirillum brasilense by absorption, circular dichroism, and electron paramagnetic resonance spectroscopies.
    Biochemistry Volume: 31 Page(s): 4613 - 4623
    05/19/1992 Authors: Vanoni MA; Edmondson DE; Zanetti G; Curti B
  • Riboflavin 5'-pyrophosphate: a contaminant of commercial FAD, a coenzyme for FAD-dependent oxidases, and an inhibitor of FAD synthetase.
    Anal Biochem Volume: 202 Page(s): 348 - 355
    05/01/1992 Authors: Hartman HA; Edmondson DE; McCormick DB
  • Effect of KCl on the interactions between NADPH:cytochrome P-450 reductase and either cytochrome c, cytochrome b5 or cytochrome P-450 in octyl glucoside micelles.
    Eur J Biochem Volume: 204 Page(s): 1075 - 1082
    03/15/1992 Authors: Nisimoto Y; Edmondson DE
  • INHIBITION OF PHOSPHATIDIC-ACID (PA) PHOSPHOHYDROLASE BLOCKS PHORBOL ESTER-STIMULATED SUPEROXIDE GENERATION IN HUMAN NEUTROPHILS
    Volume: 6 Page(s): A1923 - A1923
    02/28/1992 Authors: PERRY D; HAND WL; EDMONDSON DE
  • ESR STUDIES OF THE FE/S CENTERS OF AZOSPIRILLUM-BRASILENSE GLUTAMATE SYNTHASE
    Volume: 6 Page(s): A191 - A191
    01/01/1992 Authors: EDMONDSON DE; VANONI MA; CURTI B; ZANETTI G
  • RESONANCE RAMAN-SPECTROSCOPIC EVIDENCE FOR AN ANIONIC FLAVIN SEMIQUINONE IN BEEF-LIVER MONOAMINE-OXIDASE
    Volume: 6 Page(s): A319 - A319
    01/01/1992 Authors: ZHELYASKOV VR; BHATTACHARYYA AK; EDMONDSON DE; YUE KT
  • INVIVO PHOSPHORYLATION OF CHICKEN LIVER XANTHINE DEHYDROGENASE
    Volume: 6 Page(s): A190 - A190
    01/01/1992 Authors: SCHIEBER A; EDMONDSON DE
  • Mechanistic studies on Azospirillum brasilense glutamate synthase.
    Biochemistry Volume: 30 Page(s): 11478 - 11484
    12/03/1991 Authors: Vanoni MA; Edmondson DE; Rescigno M; Zanetti G; Curti B
  • MECHANISM OF ASSEMBLY OF THE DINUCLEAR IRON CENTER - TYROSYL RADICAL COFACTOR OF RIBONUCLEOTIDE REDUCTASE
    Volume: 202 Page(s): 22 - BIOL
    08/25/1991 Authors: STUBBE J; BOLLINGER M; EDMONDSON DE; HUYNH BH; FILLEY J; NORTON J
  • Mechanism of assembly of the tyrosyl radical-dinuclear iron cluster cofactor of ribonucleotide reductase.
    Science Volume: 253 Page(s): 292 - 298
    07/19/1991 Authors: Bollinger JM; Edmondson DE; Huynh BH; Filley J; Norton JR; Stubbe J
  • Kinetic comparison of reduction and intramolecular electron transfer in milk xanthine oxidase and chicken liver xanthine dehydrogenase by laser flash photolysis.
    Biochemistry Volume: 30 Page(s): 5912 - 5917
    06/18/1991 Authors: Walker MC; Hazzard JT; Tollin G; Edmondson DE
  • Light-dependent de-activation/re-activation of Anabaena variabilis ferredoxin: NADP+ reductase.
    Biochem J Volume: 274 ( Pt 3) Page(s): 781 - 786
    03/15/1991 Authors: Fillat MF; Edmondson DE; Gomez-Moreno C
  • GLUTAMATE SYNTHASE FROM AZOSPIRILLUM-BRASILENSE - ROLE OF FLAVINS AND IRON SULFUR CENTERS
    Page(s): 749 - 753
    01/01/1991 Authors: VANONI MA; ZANETTI G; CURTI B; EDMONDSON DE
  • ELECTRON-SPIN-RESONANCE SPECTRAL STUDIES OF N-15-H-2 FLAVIN COENZYME SEMIQUINONES IN FLAVOENZYMES
    Page(s): 67 - 72
    01/01/1991 Authors: EDMONDSON DE; MULLER F; SCHAUB F; NISIMOTO Y
  • COVALENT PHOSPHORUS GROUPS IN FLAVOPROTEINS - THE PHOSPHODIESTER LINKAGE IN AZOTOBACTER (OP) FLAVODOXIN
    Page(s): 385 - 391
    01/01/1991 Authors: EDMONDSON DE; BOYLAN M; TAYLOR M
  • EVIDENCE FOR PARTICIPATION OF THE PHOSPHOSERYL RESIDUE OF XANTHINE-OXIDASE IN THE HYDROXYLATION EVENT DURING ENZYME CATALYSIS
    Page(s): 685 - 689
    01/01/1991 Authors: DARDENNE SC; EDMONDSON DE
  • Kinetic isotope effect studies on milk xanthine oxidase and on chicken liver xanthine dehydrogenase.
    Biochemistry Volume: 29 Page(s): 9046 - 9052
    09/25/1990 Authors: D'Ardenne SC; Edmondson DE
  • Structural and chemical properties of a flavodoxin from Anabaena PCC 7119.
    Biochim Biophys Acta Volume: 1040 Page(s): 301 - 307
    09/03/1990 Authors: Fillat MF; Edmondson DE; Gomez-Moreno C
  • Azotobacter vinelandii flavodoxin: purification and properties of the recombinant, dephospho form expressed in Escherichia coli.
    Biochemistry Volume: 29 Page(s): 6911 - 6918
    07/24/1990 Authors: Taylor MF; Boylan MH; Edmondson DE
  • A 31P-nuclear-magnetic-resonance study of NADPH-cytochrome-P-450 reductase and of the Azotobacter flavodoxin/ferredoxin-NADP+ reductase complex.
    Eur J Biochem Volume: 190 Page(s): 531 - 537
    07/05/1990 Authors: Bonants PJ; Mller F; Vervoort J; Edmondson DE
  • Studies on the incorporation of a covalently bound disubstituted phosphate residue into Azotobacter vinelandii flavodoxin in vivo.
    Biochem J Volume: 268 Page(s): 745 - 749
    06/15/1990 Authors: Boylan MH; Edmondson DE
  • Preparation and properties of a cross-linked complex between ferredoxin--NADP+ reductase and flavodoxin.
    Eur J Biochem Volume: 183 Page(s): 539 - 544
    08/15/1989 Authors: Pueyo JJ; Sancho J; Edmondson DE; Gmez-Moreno C
  • Electron-nuclear double resonance spectroscopy of the desulfo-inhibited molybdenum(V) center in bovine milk xanthine oxidase.
    Biochemistry Volume: 28 Page(s): 5924 - 5930
    07/11/1989 Authors: Edmondson DE; D'Ardenne SC
  • Effect of hypoxia on tert-butylhydroperoxide-induced oxidative injury in hepatocytes.
    Mol Pharmacol Volume: 34 Page(s): 413 - 420
    09/01/1988 Authors: Tribble DL; Jones DP; Edmondson DE
  • pKa values of the 8 alpha-imidazole substituents in selected flavoenzymes containing 8 alpha-histidylflavins.
    Arch Biochem Biophys Volume: 264 Page(s): 281 - 287
    07/01/1988 Authors: De Francesco R; Edmondson DE
  • Oxidation-reduction potential studies on p-hydroxybenzoate hydroxylase from Pseudomonas fluorescens.
    Biochim Biophys Acta Volume: 953 Page(s): 258 - 262
    04/14/1988 Authors: Williamson G; Edmondson DE; Mller F
  • INVIVO STUDIES OF AZOTOBACTER FLAVODOXIN PHOSPHORYLATION
    Volume: 2 Page(s): A355 - A355
    03/15/1988 Authors: BOYLAN M; EDMONDSON DE
  • PROTON-DETECTED H-1-P-31 2D NMR-SPECTROSCOPY OF AZOTOBACTER FLAVODOXIN - EVIDENCE FOR A PHOSPHODIESTER LINKAGE BETWEEN A SERYL AND A THREONYL RESIDUE
    Volume: 2 Page(s): A355 - A355
    03/15/1988 Authors: EDMONDSON DE; LIVE D
  • PULSED ELECTRON-PARAMAGNETIC-RES STUDIES OF THE FMN NEUTRAL SEMIQUINONE OF AZOTOBACTER FLAVODOXIN
    Volume: 2 Page(s): A354 - A354
    03/15/1988 Authors: DEFRANCESCO R; EDMONDSON DE; MCCRACKEN J; PEISACH J
  • KINETIC-STUDIES OF C-H BOND-CLEAVAGE IN THE CATALYTIC MECHANISM OF XANTHINE-OXIDASE
    Volume: 2 Page(s): A587 - A587
    03/15/1988 Authors: DARDENNE S; EDMONDSON DE
  • Purification and properties of ferredoxin-NADP+ oxidoreductase from the nitrogen-fixing cyanobacteria Anabaena variabilis.
    Arch Biochem Biophys Volume: 260 Page(s): 200 - 207
    01/01/1988 Authors: Sancho J; Peleato ML; Gomez-Moreno C; Edmondson DE
  • Flavodoxin-cytochrome c interactions: circular dichroism and nuclear magnetic resonance studies.
    Biochemistry Volume: 26 Page(s): 5042 - 5048
    08/11/1987 Authors: Tollin G; Brown K; De Francesco R; Edmondson DE
  • Influence of 8 alpha-imidazole substitution of the FMN cofactor on the rate of electron transfer from the neutral semiquinones of two flavodoxins to cytochrome c.
    Biochemistry Volume: 26 Page(s): 5036 - 5042
    08/11/1987 Authors: De Francesco R; Tollin G; Edmondson DE
  • EFFECT OF THE LABILE PHOSPHORUS GROUP ON THE INTERACTIONS OF AZOTOBACTER FLAVODOXIN WITH FERREDOXIN-NADP+ OXIDOREDUCTASE FROM ANABAENA-VARIABILIS
    Volume: 45 Page(s): 1888 - 1888
    05/01/1986 Authors: SANCHO J; PELEATO ML; GOMEZMORENO C; EDMONDSON DE
  • ANDROST-5-ENE-3-BETA-OL-17-BETA-SULFATE - A WATER-SOLUBLE SUBSTRATE FOR CHOLESTEROL OXIDASE
    Volume: 45 Page(s): 1888 - 1888
    05/01/1986 Authors: EDMONDSON DE; BAKER KH; WILLIAMSON G; JACKSON K; GOLDSMITH DJ
  • INFLUENCE OF THE SIDE-CHAIN PHOSPHATE ON THE BINDING OF REDUCED FLAVIN TO AZOTOBACTER APOFLAVODOXIN
    Volume: 49 Page(s): A500 - A500
    02/01/1986 Authors: EDMONDSON DE; WILLIAMSON G
  • 1H NMR spectral analysis of the ribityl side chain of riboflavin and its ring-substituted analogs.
    Methods Enzymol Volume: 122 Page(s): 240 - 248
    01/01/1986 Authors: Williamson G; Edmondson DE
  • H-1-NMR SPECTRAL-ANALYSIS OF THE RIBITYL SIDE-CHAIN OF RIBOFLAVIN AND ITS RING-SUBSTITUTED ANALOGS
    METHODS IN ENZYMOLOGY Volume: 122 Page(s): 240 - 248
    01/01/1986 Authors: WILLIAMSON G; EDMONDSON DE
  • Proton nuclear magnetic resonance studies of 8 alpha-N-imidazolylriboflavin in its oxidized and reduced forms.
    Biochemistry Volume: 24 Page(s): 7918 - 7926
    12/31/1985 Authors: Williamson G; Edmondson DE
  • Effect of pH on oxidation-reduction potentials of 8 alpha-N-imidazole-substituted flavins.
    Biochemistry Volume: 24 Page(s): 7790 - 7797
    12/17/1985 Authors: Williamson G; Edmondson DE
  • Electron-spin-resonance studies on flavoenzymes.
    Biochem Soc Trans Volume: 13 Page(s): 593 - 600
    06/01/1985 Authors: Edmondson DE
  • Evidence for an aldehyde intermediate in the catalytic mechanism of thiamine oxidase.
    Arch Biochem Biophys Volume: 239 Page(s): 46 - 52
    05/15/1985 Authors: Gomez-Moreno C; Edmondson DE
  • N-nitrosodialkylamines do not function as substrates for liver monoamine oxidase.
    Proc Natl Acad Sci U S A Volume: 82 Page(s): 682 - 683
    02/01/1985 Authors: Edmondson DE; Bruice TC
  • H-1-NMR SPECTRAL-ANALYSIS OF THE RIBITYL SIDE-CHAIN OF VARIOUS RIBOFLAVIN ANALOGS
    Volume: 44 Page(s): 1211 - 1211
    01/01/1985 Authors: WILLIAMSON G; EDMONDSON DE
  • 31P nuclear magnetic resonance and chemical studies of the phosphorus residues in bovine milk xanthine oxidase.
    Eur J Biochem Volume: 145 Page(s): 237 - 243
    12/03/1984 Authors: Davis MD; Edmondson DE; Mller F
  • Evidence for two copper atoms/subunit in dopamine beta-monooxygenase catalysis.
    J Biol Chem Volume: 259 Page(s): 3399 - 3402
    03/25/1984 Authors: Klinman JP; Krueger M; Brenner M; Edmondson DE
  • Biochemistry.
    Science Volume: 219 Page(s): 1317
    03/18/1983 Authors: Edmondson DE
  • Kinetic properties of pyridoxamine (pyridoxine)-5'-phosphate oxidase from rabbit liver.
    J Biol Chem Volume: 258 Page(s): 840 - 845
    01/25/1983 Authors: Choi JD; Bowers-Komro M; Davis MD; Edmondson DE; McCormick DB
  • Semiquinone formation in flavo- and metalloflavoproteins.
    Top Curr Chem Volume: 108 Page(s): 109 - 138
    01/01/1983 Authors: Edmondson DE; Tollin G
  • INTRAMOLECULAR ELECTRON-TRANSFER IN XANTHINE-OXIDASE
    Volume: 41 Page(s): A392 - A392
    01/01/1983 Authors: BHATTACHARYYA A; TOLLIN G; DAVIS M; EDMONDSON DE
  • The role of the membrane in the regulation of activity of microsomal glucose-6-phosphatase.
    J Biol Chem Volume: 257 Page(s): 1145 - 1148
    02/10/1982 Authors: Zakim D; Edmondson DE
  • Kinetic studies on the catalytic mechanism of liver monoamine oxidase.
    Biochemistry Volume: 21 Page(s): 595 - 600
    02/02/1982 Authors: Husain M; Edmondson DE; Singer TP
  • CATALYTIC PROPERTIES OF OXIDASES CONTAINING COVALENTLY BOUND FLAVIN COENZYMES
    Volume: 184 Page(s): 2 - BIOL
    01/01/1982 Authors: EDMONDSON DE
  • 8 alpha-(O-Tyrosyl)flavin adenine dinucleotide, the prosthetic group of bacterial p-cresol methylhydroxylase.
    Biochemistry Volume: 20 Page(s): 3068 - 3075
    05/26/1981 Authors: McIntire W; Edmondson DE; Hopper DJ; Singer TP
  • Identification of neutral and anionic 8 alpha-substituted flavin semiquinones in flavoproteins by electron spin resonance spectroscopy.
    Arch Biochem Biophys Volume: 208 Page(s): 69 - 74
    04/15/1981 Authors: Edmondson DE; Ackrell BA; Kearney EB
  • Glucose oxidase contains a disubstituted phosphorus residue. Phosphorus-31 nuclear magnetic resonance studies of the flavin and nonflavin phosphate residues.
    Biochemistry Volume: 20 Page(s): 617 - 621
    02/03/1981 Authors: James TL; Edmondson DE; Husain M
  • Formation and mode of action of flavoproteins.
    Annu Rev Nutr Volume: 1 Page(s): 281 - 317
    01/01/1981 Authors: Merrill AH; Lambeth JD; Edmondson DE; McCormick DB
  • Suicide inhibitors of central nervous system enzymes.
    Essays Neurochem Neuropharmacol Volume: 5 Page(s): 131 - 153
    01/01/1981 Authors: Singer TP; Edmondson DE; Salach JI
  • 8 alpha-O-Tyrosyl-FAD: a new form of covalently bound flavin from p-cresol methylhydroxylase.
    J Biol Chem Volume: 255 Page(s): 6553 - 6555
    07/25/1980 Authors: McIntire W; Edmondson DE; Singer TP; Hopper DJ
  • Structure, properties, and determination of covalently bound flavins.
    Methods Enzymol Volume: 66 Page(s): 253 - 264
    01/01/1980 Authors: Singer TP; Edmondson DE
  • DEMONSTRATION OF A NEW TYPE OF COVALENT FLAVIN IN P-CRESOL-METHYLHYDROXYLASE
    Volume: 39 Page(s): 1698 - 1698
    01/01/1980 Authors: MCINTIRE W; EDMONDSON DE; SINGER TP; HOPPER DJ
  • KINETIC-STUDIES ON THE MECHANISM OF LIVER MONOAMINE-OXIDASE
    Volume: 180 Page(s): 55 - BIOL
    01/01/1980 Authors: HUSAIN M; EDMONDSON DE; SINGER TP
  • P-31 NMR-STUDIES ON THE FLAVIN AND NON-FLAVIN PHOSPHATES OF GLUCOSE-OXIDASE
    Volume: 39 Page(s): 1119 - 1119
    01/01/1980 Authors: JAMES TL; EDMONDSON DE; HUSAI M
  • Purification and properties of the bacterial flavoprotein: thiamin dehydrogenase.
    J Biol Chem Volume: 254 Page(s): 7630 - 7635
    08/25/1979 Authors: Gomez-Moreno C; Choy M; Edmondson DE
  • Covalently bound non-coenzyme phosphorus residues in flavoproteins: 31P nuclear magnetic resonance studies of Azotobacter flavodoxin.
    Proc Natl Acad Sci U S A Volume: 76 Page(s): 3786 - 3789
    08/01/1979 Authors: Edmondson DE; James TL
  • Inactivation of succinate dehydrogenase by 3-nitropropionate.
    J Biol Chem Volume: 254 Page(s): 5161 - 5167
    06/25/1979 Authors: Coles CJ; Edmondson DE; Singer TP
  • Identification of the covalently-bound flavin of L-galactonolactone oxidase from yeast.
    FEBS Lett Volume: 97 Page(s): 40 - 42
    01/01/1979 Authors: Kenney WC; Edmondson DE; Singer TP; Nishikimi M; Noguchi E; Yagi K
  • Flavoproteins (overview).
    Methods Enzymol Volume: 53 Page(s): 397 - 418
    01/01/1978 Authors: Singer TP; Edmondson DE
  • Synthesis and isolation of 8 alpha-substituted flavins and flavin peptides.
    Methods Enzymol Volume: 53 Page(s): 449 - 465
    01/01/1978 Authors: Edmondson DE; Kenney WC; Singer TP
  • Reversible inactivation of L-amino acid oxidase. Properties of the three conformational forms.
    J Biol Chem Volume: 252 Page(s): 8035 - 8039
    11/25/1977 Authors: Coles CJ; Edmondson DE; Singer TP
  • 2',5'-Anhydro-8alpha-histidylflavins: their formation and structural elucidation.
    Biochemistry Volume: 16 Page(s): 4308 - 4311
    09/20/1977 Authors: Edmondson DE
  • The effect of 8alpha-substitution on flavin triplet state and semiquinone properties as investigated by flash photolysis.
    Photochem Photobiol Volume: 25 Page(s): 445 - 450
    05/01/1977 Authors: Edmondson DE; Rizzuto F; Tollin G
  • Identification and properties of the covalently bound flavin of beta-cyclopiazonate oxidocyclase.
    Biochemistry Volume: 15 Page(s): 4931 - 4935
    11/02/1976 Authors: Kenney WC; Edmondson DE; Singer TP; Steenkamp DJ; Schabort JC
  • Identification of the covalently bound flavin of thiamin dehydrogenase.
    J Biol Chem Volume: 251 Page(s): 5386 - 5390
    09/10/1976 Authors: Kenney WC; Edmondson DE; Seng RL
  • Identification of the covalently bound flavin of L-gulono-gamma-lactone oxidase.
    Biochem Biophys Res Commun Volume: 71 Page(s): 1194 - 1200
    08/23/1976 Authors: Kenney WC; Edmondson DE; Singer TP
  • Structural elucidation and properties of 8alpha-(N1-histidyl)riboflavin: the flavin component of thiamine dehydrogenase and beta-cyclopiazonate oxidocyclase.
    Biochemistry Volume: 15 Page(s): 2937 - 2945
    07/13/1976 Authors: Edmondson DE; Kenney WC; Singer TP
  • 8alpha-substituted flavins of biological importance: an updating.
    FEBS Lett Volume: 64 Page(s): 255 - 265
    05/01/1976 Authors: Edmondson DE; Singer TP
  • Identification and properties of 8alpha-(N(1)-histidyl)-riboflavin: the flavin component of thiamine dehydrogenase and beta-cyclopiazonate oxidocyclase.
    Biochem Biophys Res Commun Volume: 68 Page(s): 242 - 248
    01/12/1976 Authors: Edmondson DE; Kenney WC
  • 2',5'-ANHYDRO-8-ALPHA-HISTIDYL FLAVINS - THEIR OCCURRENCE AND STRUCTURAL ELUCIDATION
    Volume: 35 Page(s): 1542 - 1542
    01/01/1976 Authors: EDMONDSON DE
  • IDENTIFICATION OF STRUCTURE OF COVALENTLY BOUND FLAVIN COENZYME OF THIAMINE DEHYDROGENASE AND BETA-CYCLOPIAZONATE OXIDOCYCLASE
    Volume: 35 Page(s): 1542 - 1542
    01/01/1976 Authors: KENNEY WC; EDMONDSON DE
  • 2',5'-ANHYDRO-8-ALPHA-HISTIDYL FLAVINS - THEIR OCCURRENCE AND STRUCTURAL ELUCIDATION
    Volume: 172 Page(s): 147 - 147
    01/01/1976 Authors: EDMONDSON DE
  • Mechanism of the reductive activation of succinate dehydrogenase.
    J Biol Chem Volume: 250 Page(s): 7114 - 7119
    09/25/1975 Authors: Ackrell BA; Kearney EB; Edmondson D
  • The covalently bound flavin of Chromatium cytochrome c552. 2. Sequence of flavin peptides and flavin-tyrosine interaction.
    Eur J Biochem Volume: 48 Page(s): 449 - 453
    10/02/1974 Authors: Kenney WC; Edmondson DE; Singer TP
  • The covalently bound flavin of Chromatium cytochrome c552. 1. Evidence for cysteine thiohemiacetal at the 8 alpha position.
    Eur J Biochem Volume: 48 Page(s): 439 - 448
    10/02/1974 Authors: Walker WH; Kenney WC; Edmondson DE; Singer TP; Cronin JR; Hendriks R
  • Intramolecular hemiacetal formation in 8-formylriboflavine.
    Biochemistry Volume: 13 Page(s): 2817 - 2821
    07/02/1974 Authors: Edmondson DE
  • 8 alpha-substituted flavins of biological importance.
    FEBS Lett Volume: 42 Page(s): 1 - 14
    05/15/1974 Authors: Singer TP; Edmondson DE
  • The covalently bound flavin prosthetic group of beta-cyclopiazonate oxidocyclase.
    FEBS Lett Volume: 41 Page(s): 111 - 114
    04/15/1974 Authors: Kenney WC; Edmondson DE; Singer TP; Steenkamp DJ; Schabort JC
  • A novel form of covalently bound flavin from thiamine dehydrogenase.
    Biochem Biophys Res Commun Volume: 57 Page(s): 106 - 111
    03/15/1974 Authors: Kenney WC; Edmondson DE; Singer TP
  • Oxidation-reduction properties of the 8 alpha-substituted flavins.
    J Biol Chem Volume: 248 Page(s): 8144 - 8149
    12/10/1973 Authors: Edmondson DE; Singer TP
  • Kinetic studies on the substrate reduction of xanthine oxidase.
    J Biol Chem Volume: 248 Page(s): 6135 - 6144
    09/10/1973 Authors: Edmondson D; Ballou D; Van Heuvelen A; Palmer G; Massey V
  • Structure of the flavin site of Chromatium flavocytochrome c -552 .
    Biochem Biophys Res Commun Volume: 52 Page(s): 434 - 439
    05/15/1973 Authors: Kenney WC; Edmondson D; Seng R; Singer TP
  • The separation of functional and non-functional xanthine oxidase by affinity chromatography.
    Biochem J Volume: 127 Page(s): 10P - 11P
    04/01/1972 Authors: Massey V; Edmondson D; Palmer G; Beacham LM; Elion GB
  • On the importance of the N-5 position in flavin coenzymes. Properties of free and protein-bound 5-deaza analogs.
    Biochemistry Volume: 11 Page(s): 1133 - 1138
    03/28/1972 Authors: Edmondson DE; Barman B; Tollin G
  • The resolution of active and inactive xanthine oxidase by affinity chromatography.
    J Biol Chem Volume: 247 Page(s): 1597 - 1604
    03/10/1972 Authors: Edmondson D; Massey V; Palmer G; Beacham LM; Elion GB
  • The isolation and characterization of Rhodospirillum rubrum flavodoxin.
    Biochem Biophys Res Commun Volume: 45 Page(s): 327 - 336
    10/15/1971 Authors: Cusanovich MA; Edmondson DE
  • Flavin-protein interactions and the redox properties of the Shethna flavoprotein.
    Biochemistry Volume: 10 Page(s): 133 - 145
    01/05/1971 Authors: Edmondson DE; Tollin G
  • Chemical and physical characterization of the Shethna flavoprotein and apoprotein and kinetics and thermodynamics of flavin analog binding to the apoprotein.
    Biochemistry Volume: 10 Page(s): 124 - 132
    01/05/1971 Authors: Edmondson DE; Tollin G
  • Circular dichroism studies of the flavin chromophore and of the relation between redox properties and flavin environment in oxidases and dehydrogenases.
    Biochemistry Volume: 10 Page(s): 113 - 124
    01/05/1971 Authors: Edmondson DE; Tollin G
  • On the mechanism of inactivation of xanthine oxidase by cyanide.
    J Biol Chem Volume: 245 Page(s): 6595 - 6598
    12/25/1970 Authors: Massey V; Edmondson D
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