Dale Edmondson PhD
Academic Appointment
- Adjunct Professor of Chemistry, Emory University School of Medicine
- Professor, Department of Biochemistry, Emory University School of Medicine
- Professor of Biochemistry, Emory University School of Medicine
Education
Degrees
- PhD from University of Arizona
- BS from Northern Illinois University
Research
Focus
- Flavin chemistry and flavoenzyme catalysis, mechanism of action of molybdoenzymes, dinuclear iron structure and function.
Publications
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Crystallization of Human Monoamine Oxidase B.
Methods Mol Biol Volume: 2558 Page(s): 115 - 122
01/01/2023 Authors: Binda C; Edmondson DE; Mattevi A -
Purification of Recombinant Eukaryotic MAO A and MAO B Utilizing the Pichia pastoris Expression System.
Methods Mol Biol Volume: 2558 Page(s): 11 - 22
01/01/2023 Authors: Edmondson DE -
Purification of MAO A and MAO B from Mammalian Tissue Sources.
Methods Mol Biol Volume: 2558 Page(s): 1 - 10
01/01/2023 Authors: Edmondson DE -
Rational Redesign of Monoamine Oxidase A into a Dehydrogenase to Probe ROS in Cardiac Aging.
ACS Chem Biol Volume: 15 Page(s): 1795 - 1800
07/17/2020 Authors: Iacovino LG; Manzella N; Resta J; Vanoni MA; Rotilio L; Pisani L; Edmondson DE; Parini A; Mattevi A; Mialet-Perez J -
Monoamine Oxidases.
Subcell Biochem Volume: 87 Page(s): 117 - 139
01/01/2018 Authors: Edmondson DE; Binda C -
Biosensor for the characterisation of hMAO B inhibitors and the quantification of selegiline.
Talanta Volume: 174 Page(s): 696 - 702
11/01/2017 Authors: Aigner M; Preissegger P; Kalcher K; Mehmeti E; Macheroux P; Edmondson D; Ortner A -
Monoamine Oxidases, Oxidative Stress, and Altered Mitochondrial Dynamics in Cardiac Ageing.
Oxid Med Cell Longev Volume: 2017 Page(s): 3017947
01/01/2017 Authors: Maggiorani D; Manzella N; Edmondson DE; Mattevi A; Parini A; Binda C; Mialet-Perez J -
Design and synthesis of novel chalcones as potent selective monoamine oxidase-B inhibitors.
Eur J Med Chem Volume: 114 Page(s): 162 - 169
05/23/2016 Authors: Hammuda A; Shalaby R; Rovida S; Edmondson DE; Binda C; Khalil A -
Why p-OMe- and p-Cl--Methylphenethylamines Display Distinct Activities upon MAO-B Binding.
PLoS One Volume: 11 Page(s): e0154989
01/01/2016 Authors: Fierro A; Edmondson DE; Celis-Barros C; Rebolledo-Fuentes M; Zapata-Torres G -
Reversible and irreversible small molecule inhibitors of monoamine oxidase B (MAO-B) investigated by biophysical techniques.
Bioorg Med Chem Volume: 23 Page(s): 770 - 778
02/15/2015 Authors: Rojas RJ; Edmondson DE; Almos T; Scott R; Massari ME -
Hydrogen peroxide produced by mitochondrial monoamine oxidase catalysis: biological implications.
Curr Pharm Des Volume: 20 Page(s): 155 - 160
01/01/2014 Authors: Edmondson DE -
Truncated FAD synthetase for direct biocatalytic conversion of riboflavin and analogs to their corresponding flavin mononucleotides.
Protein Eng Des Sel Volume: 26 Page(s): 791 - 795
12/01/2013 Authors: Iamurri SM; Daugherty AB; Edmondson DE; Lutz S -
Do MAO A and MAO B utilize the same mechanism for the C-H bond cleavage step in catalysis? Evidence suggesting differing mechanisms.
J Neural Transm (Vienna) Volume: 120 Page(s): 847 - 851
06/01/2013 Authors: Orru R; Aldeco M; Edmondson DE -
Mirroring human monoamine oxidases A and B: Similar structures with opposite mechanisms of C-H bond cleavage
Volume: 27
04/01/2013 Authors: Orru R; Aldeco M; Edmondson DE -
Beyond the Protein Matrix: Probing Cofactor Variants in a Baeyer-Villiger Oxygenation Reaction.
ACS Catal Volume: 3 Page(s): 3058 - 3062
01/01/2013 Authors: Martinoli C; Dudek HM; Orru R; Edmondson DE; Fraaije MW; Mattevi A -
Precursor of ether phospholipids is synthesized by a flavoenzyme through covalent catalysis.
Proc Natl Acad Sci U S A Volume: 109 Page(s): 18791 - 18796
11/13/2012 Authors: Nenci S; Piano V; Rosati S; Aliverti A; Pandini V; Fraaije MW; Heck AJR; Edmondson DE; Mattevi A -
Structural basis for benzothiazinone-mediated killing of Mycobacterium tuberculosis.
Sci Transl Med Volume: 4 Page(s): 150ra121
09/05/2012 Authors: Neres J; Pojer F; Molteni E; Chiarelli LR; Dhar N; Boy-Rttger S; Buroni S; Fullam E; Degiacomi G; Lucarelli AP -
The 'gating' residues Ile199 and Tyr326 in human monoamine oxidase B function in substrate and inhibitor recognition.
FEBS J Volume: 278 Page(s): 4860 - 4869
12/01/2011 Authors: Milczek EM; Binda C; Rovida S; Mattevi A; Edmondson DE -
Lights and shadows on monoamine oxidase inhibition in neuroprotective pharmacological therapies.
Curr Top Med Chem Volume: 11 Page(s): 2788 - 2796
11/01/2011 Authors: Binda C; Milczek EM; Bonivento D; Wang J; Mattevi A; Edmondson DE -
Molecular Insights into Human Monoamine Oxidase B Inhibition by the Glitazone Anti-Diabetes Drugs.
ACS Med Chem Lett Volume: 3 Page(s): 39 - 42
10/15/2011 Authors: Binda C; Aldeco M; Geldenhuys WJ; Tortorici M; Mattevi A; Edmondson DE -
H kinetic isotope effects and pH dependence of catalysis as mechanistic probes of rat monoamine oxidase A: comparisons with the human enzyme.
Biochemistry Volume: 50 Page(s): 7710 - 7717
09/06/2011 Authors: Wang J; Edmondson DE -
Nitrogen kinetic isotope effects for the monoamine oxidase B-catalyzed oxidation of benzylamine and (1,1-(2)H2)benzylamine: nitrogen rehybridization and CH bond cleavage are not concerted.
J Am Chem Soc Volume: 133 Page(s): 12319 - 12321
08/17/2011 Authors: MacMillar S; Edmondson DE; Matsson O -
Catalytic and inhibitor binding properties of zebrafish monoamine oxidase (zMAO): comparisons with human MAO A and MAO B.
Comp Biochem Physiol B Biochem Mol Biol Volume: 159 Page(s): 78 - 83
06/01/2011 Authors: Aldeco M; Arslan BK; Edmondson DE -
Topological probes of monoamine oxidases A and B in rat liver mitochondria: inhibition by TEMPO-substituted pargyline analogues and inactivation by proteolysis.
Biochemistry Volume: 50 Page(s): 2499 - 2505
04/05/2011 Authors: Wang J; Edmondson DE -
Interactions of monoamine oxidases with the antiepileptic drug zonisamide: specificity of inhibition and structure of the human monoamine oxidase B complex.
J Med Chem Volume: 54 Page(s): 909 - 912
02/10/2011 Authors: Binda C; Aldeco M; Mattevi A; Edmondson DE -
Structural properties of human monoamine oxidases A and B.
Int Rev Neurobiol Volume: 100 Page(s): 1 - 11
01/01/2011 Authors: Binda C; Mattevi A; Edmondson DE -
Potentiation of ligand binding through cooperative effects in monoamine oxidase B.
J Biol Chem Volume: 285 Page(s): 36849 - 36856
11/19/2010 Authors: Bonivento D; Milczek EM; McDonald GR; Binda C; Holt A; Edmondson DE; Mattevi A -
Biochemical, structural, and biological evaluation of tranylcypromine derivatives as inhibitors of histone demethylases LSD1 and LSD2.
J Am Chem Soc Volume: 132 Page(s): 6827 - 6833
05/19/2010 Authors: Binda C; Valente S; Romanenghi M; Pilotto S; Cirilli R; Karytinos A; Ciossani G; Botrugno OA; Forneris F; Tardugno M -
High-level expression and purification of rat monoamine oxidase A (MAO A) in Pichia pastoris: comparison with human MAO A.
Protein Expr Purif Volume: 70 Page(s): 211 - 217
04/01/2010 Authors: Wang J; Edmondson DE -
Expression of zebrafish (Danio rerio) monoamine oxidase (MAO) in Pichia pastoris: purification and comparison with human MAO A and MAO B.
Protein Expr Purif Volume: 70 Page(s): 290 - 297
04/01/2010 Authors: Arslan BK; Edmondson DE -
2-Arylthiomorpholine derivatives as potent and selective monoamine oxidase B inhibitors.
Bioorg Med Chem Volume: 18 Page(s): 1388 - 1395
02/15/2010 Authors: Lhr S; Vilches-Herrera M; Fierro A; Ramsay RR; Edmondson DE; Reyes-Parada M; Cassels BK; Iturriaga-Vsquez P -
Dual role of FMN in flavodoxin function: electron transfer cofactor and modulation of the protein-protein interaction surface.
Biochim Biophys Acta Volume: 1797 Page(s): 262 - 271
02/01/2010 Authors: Frago S; Lans I; Navarro JA; Hervs M; Edmondson DE; De la Rosa MA; Gmez-Moreno C; Mayhew SG; Medina M -
Serine 209 resides within a putative p38(MAPK) consensus motif and regulates monoamine oxidase-A activity.
J Neurochem Volume: 111 Page(s): 101 - 110
10/01/2009 Authors: Cao X; Rui L; Pennington PR; Chlan-Fourney J; Jiang Z; Wei Z; Li X-M; Edmondson DE; Mousseau DD -
Mutagenic probes of the role of Ser209 on the cavity shaping loop of human monoamine oxidase A.
FEBS J Volume: 276 Page(s): 4569 - 4581
08/01/2009 Authors: Wang J; Harris J; Mousseau DD; Edmondson DE -
Molecular and mechanistic properties of the membrane-bound mitochondrial monoamine oxidases.
Biochemistry Volume: 48 Page(s): 4220 - 4230
05/26/2009 Authors: Edmondson DE; Binda C; Wang J; Upadhyay AK; Mattevi A -
Development of spin-labeled pargyline analogues as specific inhibitors of human monoamine oxidases A and B.
Biochemistry Volume: 48 Page(s): 3928 - 3935
05/12/2009 Authors: Upadhyay AK; Edmondson DE -
Inhibition of monoamine oxidase by (E)-styrylisatin analogues.
Bioorg Med Chem Lett Volume: 19 Page(s): 2509 - 2513
05/01/2009 Authors: Van der Walt EM; Milczek EM; Malan SF; Edmondson DE; Castagnoli N; Bergh JJ; Petzer JP -
Structural and mechanistic studies of mofegiline inhibition of recombinant human monoamine oxidase B.
J Med Chem Volume: 51 Page(s): 8019 - 8026
12/25/2008 Authors: Milczek EM; Bonivento D; Binda C; Mattevi A; McDonald IA; Edmondson DE -
Bioactive contaminants leach from disposable laboratory plasticware.
Science Volume: 322 Page(s): 917
11/07/2008 Authors: McDonald GR; Hudson AL; Dunn SMJ; You H; Baker GB; Whittal RM; Martin JW; Jha A; Edmondson DE; Holt A -
Characterization of detergent purified recombinant rat liver monoamine oxidase B expressed in Pichia pastoris.
Protein Expr Purif Volume: 59 Page(s): 349 - 356
06/01/2008 Authors: Upadhyay AK; Edmondson DE -
Structural and mechanistic studies of arylalkylhydrazine inhibition of human monoamine oxidases A and B.
Biochemistry Volume: 47 Page(s): 5616 - 5625
05/20/2008 Authors: Binda C; Wang J; Li M; Hubalek F; Mattevi A; Edmondson DE -
Stereochemical studies on the novel monoamine oxidase B substrates (1R,6S)- and (1S,6R)-3-methyl-6-phenyl-3-aza-bicyclo[4.1.0]heptane.
Bioorg Med Chem Volume: 16 Page(s): 3557 - 3564
04/01/2008 Authors: Bissel P; Khalil A; Rimoldi JM; Igarashi K; Edmondson D; Miller A; Castagnoli N -
Determination of the oligomeric states of human and rat monoamine oxidases in the outer mitochondrial membrane and octyl beta-D-glucopyranoside micelles using pulsed dipolar electron spin resonance spectroscopy.
Biochemistry Volume: 47 Page(s): 1554 - 1566
02/12/2008 Authors: Upadhyay AK; Borbat PP; Wang J; Freed JH; Edmondson DE -
Comparison of the structural properties of the active site cavities of human and rat monoamine oxidase A and B in their soluble and membrane-bound forms.
Biochemistry Volume: 47 Page(s): 526 - 536
01/15/2008 Authors: Upadhyay AK; Wang J; Edmondson DE -
AZOTOBACTER VINELANDII NITROGENASE MoFe PROTEIN: PRE-STEADY STATE SPECTROSCOPIC STUDIES OF THE METAL COFACTORS
Volume: 42 Page(s): 331 - 333
01/01/2008 Authors: Newton WE; Fisher K; Huynh BH; Edmondson DE; Tavares P; Pereira AS; Lowe DJ -
Monoamine oxidases and LSD1: Similar chemistry for neurotransmitter and chromatin modification
Volume: 64 Page(s): C37 - C38
01/01/2008 Authors: Mattevi A; Forneris F; Edmondson DE; Binda C -
Structures of human monoamine oxidase B complexes with selective noncovalent inhibitors: safinamide and coumarin analogs.
J Med Chem Volume: 50 Page(s): 5848 - 5852
11/15/2007 Authors: Binda C; Wang J; Pisani L; Caccia C; Carotti A; Salvati P; Edmondson DE; Mattevi A -
Conformations generated during turnover of the Azotobacter vinelandii nitrogenase MoFe protein and their relationship to physiological function.
J Inorg Biochem Volume: 101 Page(s): 1649 - 1656
11/01/2007 Authors: Fisher K; Lowe DJ; Tavares P; Pereira AS; Huynh BH; Edmondson D; Newton WE -
Structural insights into the mechanism of amine oxidation by monoamine oxidases A and B.
Arch Biochem Biophys Volume: 464 Page(s): 269 - 276
08/15/2007 Authors: Edmondson DE; Binda C; Mattevi A -
Human and rat monoamine oxidase-A are differentially inhibited by (S)-4-alkylthioamphetamine derivatives: insights from molecular modeling studies.
Bioorg Med Chem Volume: 15 Page(s): 5198 - 5206
08/01/2007 Authors: Fierro A; Osorio-Olivares M; Cassels BK; Edmondson DE; Seplveda-Boza S; Reyes-Parada M -
Plasmalogen assembly: a key flavoenzyme.
Structure Volume: 15 Page(s): 639 - 641
06/01/2007 Authors: Edmondson DE -
Do monomeric vs dimeric forms of MAO-A make a difference? A direct comparison of the catalytic properties of rat and human MAO-A's.
J Neural Transm (Vienna) Volume: 114 Page(s): 721 - 724
01/01/2007 Authors: Wang J; Edmondson DE -
New insights into the structures and functions of human monoamine oxidases A and B.
J Neural Transm (Vienna) Volume: 114 Page(s): 703 - 705
01/01/2007 Authors: Edmondson DE; DeColibus L; Binda C; Li M; Mattevi A -
Kinetic properties of recombinant MAO-A on incorporation into phospholipid nanodisks.
J Neural Transm (Vienna) Volume: 114 Page(s): 699 - 702
01/01/2007 Authors: Cruz F; Edmondson DE -
The aromatic cage in the active site of monoamine oxidase B: effect on the structural and electronic properties of bound benzylamine and p-nitrobenzylamine.
J Neural Transm (Vienna) Volume: 114 Page(s): 693 - 698
01/01/2007 Authors: Akyz MA; Erdem SS; Edmondson DE -
Functional role of the "aromatic cage" in human monoamine oxidase B: structures and catalytic properties of Tyr435 mutant proteins.
Biochemistry Volume: 45 Page(s): 4775 - 4784
04/18/2006 Authors: Li M; Binda C; Mattevi A; Edmondson DE -
The therapeutic potential of monoamine oxidase inhibitors.
Nat Rev Neurosci Volume: 7 Page(s): 295 - 309
04/01/2006 Authors: Youdim MBH; Edmondson D; Tipton KF -
Studies on the role of lysine-296 in human mitochondrial monoamine oxidase B catalysis
Volume: 20 Page(s): A478 - A479
03/06/2006 Authors: Kacar B; Edmondson DE -
Binding of rasagiline-related inhibitors to human monoamine oxidases: a kinetic and crystallographic analysis.
J Med Chem Volume: 48 Page(s): 8148 - 8154
12/29/2005 Authors: Binda C; Hublek F; Li M; Herzig Y; Sterling J; Edmondson DE; Mattevi A -
Three-dimensional structure of human monoamine oxidase A (MAO A): relation to the structures of rat MAO A and human MAO B.
Proc Natl Acad Sci U S A Volume: 102 Page(s): 12684 - 12689
09/06/2005 Authors: De Colibus L; Li M; Binda C; Lustig A; Edmondson DE; Mattevi A -
Demonstration of isoleucine 199 as a structural determinant for the selective inhibition of human monoamine oxidase B by specific reversible inhibitors.
J Biol Chem Volume: 280 Page(s): 15761 - 15766
04/22/2005 Authors: Hublek F; Binda C; Khalil A; Li M; Mattevi A; Castagnoli N; Edmondson DE -
Oxygen isotope effects on electron transfer to O-2 probed using chemically modified flavins bound to glucose oxidase
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY Volume: 127 Page(s): 5727 - 5727
04/20/2005 Authors: Roth JP; Wincek R; Nodet G; Edmondson DE; McIntire WS; Klinman JP -
Oxygen isotope effects on electron transfer to O2 probed using chemically modified flavins bound to glucose oxidase.
J Am Chem Soc Volume: 126 Page(s): 15120 - 15131
11/24/2004 Authors: Roth JP; Wincek R; Nodet G; Edmondson DE; McIntire WS; Klinman JP -
High-level expression and characterization of a highly functional Comamonas acidovorans xanthine dehydrogenase in Pseudomonas aeruginosa.
Protein Expr Purif Volume: 37 Page(s): 72 - 82
09/01/2004 Authors: Ivanov NV; Trani M; Edmondson DE -
Structure and mechanism of monoamine oxidase.
Curr Med Chem Volume: 11 Page(s): 1983 - 1993
08/01/2004 Authors: Edmondson DE; Mattevi A; Binda C; Li M; Hublek F -
Crystal structure of human monoamine oxidase B, a drug target enzyme monotopically inserted into the mitochondrial outer membrane.
FEBS Lett Volume: 564 Page(s): 225 - 228
04/30/2004 Authors: Binda C; Hublek F; Li M; Edmondson DE; Mattevi A -
Inactivation of purified human recombinant monoamine oxidases A and B by rasagiline and its analogues.
J Med Chem Volume: 47 Page(s): 1760 - 1766
03/25/2004 Authors: Hublek F; Binda C; Li M; Herzig Y; Sterling J; Youdim MBH; Mattevi A; Edmondson DE -
Crystal structures of monoamine oxidase B in complex with four inhibitors of the N-propargylaminoindan class.
J Med Chem Volume: 47 Page(s): 1767 - 1774
03/25/2004 Authors: Binda C; Hublek F; Li M; Herzig Y; Sterling J; Edmondson DE; Mattevi A -
The FAD binding sites of human monoamine oxidases A and B.
Neurotoxicology Volume: 25 Page(s): 63 - 72
01/01/2004 Authors: Edmondson DE; Binda C; Mattevi A -
Structure of the human outer-mitochondrial membrane Monoamine Oxidase B at 1.7 angstrom resolution
Volume: 60 Page(s): S22 - S22
01/01/2004 Authors: Mattevi A; Li M; Hubalek F; Edmondson DE; Binda C -
Factors involved in the assembly of a functional molybdopyranopterin center in recombinant Comamonas acidovorans xanthine dehydrogenase.
Eur J Biochem Volume: 270 Page(s): 4744 - 4754
12/01/2003 Authors: Ivanov NV; Hublek F; Trani M; Edmondson DE -
Ability of tetrahydrobiopterin analogues to support catalysis by inducible nitric oxide synthase: formation of a pterin radical is required for enzyme activity.
Biochemistry Volume: 42 Page(s): 13287 - 13303
11/18/2003 Authors: Hurshman AR; Krebs C; Edmondson DE; Marletta MA -
Polystyrene microbridges used in sitting-drop crystallization release 1,4-diphenyl-2-butene, a novel inhibitor of human MAO B.
Acta Crystallogr D Biol Crystallogr Volume: 59 Page(s): 1874 - 1876
10/01/2003 Authors: Hublek F; Binda C; Li M; Mattevi A; Edmondson DE -
Insights into the mode of inhibition of human mitochondrial monoamine oxidase B from high-resolution crystal structures.
Proc Natl Acad Sci U S A Volume: 100 Page(s): 9750 - 9755
08/19/2003 Authors: Binda C; Li M; Hubalek F; Restelli N; Edmondson DE; Mattevi A -
Structural comparison of human monoamine oxidases A and B: mass spectrometry monitoring of cysteine reactivities.
J Biol Chem Volume: 278 Page(s): 28612 - 28618
08/01/2003 Authors: Hubalek F; Pohl J; Edmondson DE -
Structure-function relationships in flavoenzyme-dependent amine oxidations: a comparison of polyamine oxidase and monoamine oxidase.
J Biol Chem Volume: 277 Page(s): 23973 - 23976
07/05/2002 Authors: Binda C; Mattevi A; Edmondson DE -
Synthesis and characterization of a collagen model delta-O-phosphohydroxylysine-containing peptide.
Anal Biochem Volume: 306 Page(s): 124 - 134
07/01/2002 Authors: Hublek F; Edmondson DE; Pohl J -
Phentermine inhibition of recombinant human liver monoamine oxidases A and B.
Biochem Pharmacol Volume: 63 Page(s): 865 - 869
03/01/2002 Authors: Nandigama RK; Newton-Vinson P; Edmondson DE -
High-level expression of human liver monoamine oxidase A in Pichia pastoris: comparison with the enzyme expressed in Saccharomyces cerevisiae.
Protein Expr Purif Volume: 24 Page(s): 152 - 162
02/01/2002 Authors: Li M; Hublek F; Newton-Vinson P; Edmondson DE -
Structure of human monoamine oxidase B, a drug target for the treatment of neurological disorders.
Nat Struct Biol Volume: 9 Page(s): 22 - 26
01/01/2002 Authors: Binda C; Newton-Vinson P; Hublek F; Edmondson DE; Mattevi A -
STRUCTURE OF HUMAN MONOAMINE OXIDASE B, A DRUG TARGET FOR NEUROLOGICAL DISORDERS
Volume: 58 Page(s): C246 - C246
01/01/2002 Authors: Mattevi A; Edmondson DE; Binda C -
Demonstration of peroxodiferric intermediate in M-ferritin ferroxidase reaction using rapid freeze-quench Mssbauer, resonance Raman, and XAS spectroscopies.
Methods Enzymol Volume: 354 Page(s): 436 - 454
01/01/2002 Authors: Krebs C; Edmondson DE; Huynh BH -
Loss of serotonin oxidation as a component of the altered substrate specificity in the Y444F mutant of recombinant human liver MAO A.
Biochemistry Volume: 40 Page(s): 14839 - 14846
12/11/2001 Authors: Nandigama RK; Miller JR; Edmondson DE -
The covalent FAD of monoamine oxidase: structural and functional role and mechanism of the flavinylation reaction.
Antioxid Redox Signal Volume: 3 Page(s): 789 - 806
10/01/2001 Authors: Edmondson DE; Newton-Vinson P -
Properties of C-terminal truncated mutants of monoamine oxidase B
Volume: 15 Page(s): A524 - A524
03/07/2001 Authors: Newton-Vinson P; Edmondson DE -
Structure-activity relations in the oxidation of phenethylamine analogues by recombinant human liver monoamine oxidase A.
Biochemistry Volume: 39 Page(s): 15258 - 15265
12/12/2000 Authors: Nandigama RK; Edmondson DE -
High-level expression of human liver monoamine oxidase B in Pichia pastoris.
Protein Expr Purif Volume: 20 Page(s): 334 - 345
11/01/2000 Authors: Newton-Vinson P; Hubalek F; Edmondson DE -
Influence of FAD structure on its binding and activity with the C406A mutant of recombinant human liver monoamine oxidase A.
J Biol Chem Volume: 275 Page(s): 20527 - 20532
07/07/2000 Authors: Nandigama RK; Edmondson DE -
Evidence for alternative binding modes in the interaction of benzylamine analogues with bovine liver monoamine oxidase B.
Biochim Biophys Acta Volume: 1479 Page(s): 52 - 58
06/15/2000 Authors: Edmondson DE; Bhattacharrya AK; Xu J -
Evidence for alternative binding modes in the interaction of benzylamine analogs with bovine liver monoamine oxidase B (MAOB).
Volume: 14 Page(s): A1416 - A1416
05/11/2000 Authors: Bhattacharyya AK; Edmondson DE; Xu JJ -
A short Fe-Fe distance in peroxodiferric ferritin: control of Fe substrate versus cofactor decay?
Science Volume: 287 Page(s): 122 - 125
01/07/2000 Authors: Hwang J; Krebs C; Huynh BH; Edmondson DE; Theil EC; Penner-Hahn JE -
The FAD binding sites of human liver monoamine oxidases A and B: investigation of the role of flavin ribityl side chain hydroxyl groups in the covalent flavinylation reaction and catalytic activities.
Biochim Biophys Acta Volume: 1476 Page(s): 27 - 32
01/03/2000 Authors: Miller JR; Guan N; Hubalek F; Edmondson DE -
Formation of a pterin radical in the reaction of the heme domain of inducible nitric oxide synthase with oxygen.
Biochemistry Volume: 38 Page(s): 15689 - 15696
11/30/1999 Authors: Hurshman AR; Krebs C; Edmondson DE; Huynh BH; Marletta MA -
Structure-activity relationships in the oxidation of para-substituted benzylamine analogues by recombinant human liver monoamine oxidase A.
Biochemistry Volume: 38 Page(s): 13670 - 13683
10/12/1999 Authors: Miller JR; Edmondson DE -
Influence of flavin analogue structure on the catalytic activities and flavinylation reactions of recombinant human liver monoamine oxidases A and B.
J Biol Chem Volume: 274 Page(s): 23515 - 23525
08/13/1999 Authors: Miller JR; Edmondson DE -
Rapid freeze-quench mossbauer investigations of intermediates in oxygen activation reactions of carboxylate-bridged diiron proteins
Volume: 74 Page(s): 33 - 33
04/30/1999 Authors: Krebs C; Edmondson DE; Huynh BH -
Mossbauer and EPR spectroscopic evidence for spin-coupled X-protein radical intermediates during oxygen activation of ribonucleotide reductase R2 protein from E-coli
Volume: 74 Page(s): 195 - 195
04/30/1999 Authors: Krebs C; Baldwin J; Chen S; Ley BA; Edmondson DE; Bollinger JM; Huynh BH -
Rational engineering of the R2 subunit of Escherichia coli ribonucleotide reductase into a self-hydroxylating monooxygenase
Volume: 74 Page(s): 74 - 74
04/30/1999 Authors: Baldwin J; Moenne-Loccoz P; Krebs C; Ley BA; Edmondson DE; Huynh BH; Loehr TM; Bollinger JM -
Structural determinants of the mechanisms and outcomes of O-2 activation by the diiron carboxylate proteins
Volume: 74 Page(s): 13 - 13
04/30/1999 Authors: Bollinger JM; Baldwin J; Krebs C; Chen S; Ley BA; Edmondson DE; Huynh BH -
The ferroxidase reaction of ferritin reveals a diferric mu-1,2 bridging peroxide intermediate in common with other O2-activating non-heme diiron proteins.
Biochemistry Volume: 38 Page(s): 5290 - 5295
04/27/1999 Authors: Monne-Loccoz P; Krebs C; Herlihy K; Edmondson DE; Theil EC; Huynh BH; Loehr TM -
Influence of isoalloxazine modification on the activity of human liver monoamine oxidase a C406A mutant expressed in Saccharomyces cerevisiae.
Volume: 13 Page(s): A1436 - A1436
04/23/1999 Authors: Nandigama RK; Edmondson DE -
Expression, purification, and characterization of human liver MAO B from Pichia pastoris
Volume: 13 Page(s): A1437 - A1437
04/23/1999 Authors: Newton-Vinson AP; Edmondson DE -
Benzylamine analog binding studies as probes of the substrate sites of monoamine oxidases A and B.
Drug Metab Rev Volume: 31 Page(s): 235 - 245
02/01/1999 Authors: Edmondson DE -
Flavoenzyme structure and function. Approaches using flavin analogues.
Methods Mol Biol Volume: 131 Page(s): 157 - 179
01/01/1999 Authors: Edmondson D; Ghisla S -
Direct spectroscopic and kinetic evidence for the involvement of a peroxodiferric intermediate during the ferroxidase reaction in fast ferritin mineralization.
Biochemistry Volume: 37 Page(s): 9871 - 9876
07/14/1998 Authors: Pereira AS; Small W; Krebs C; Tavares P; Edmondson DE; Theil EC; Huynh BH -
Characterization of Y122F R2 of Escherichia coli ribonucleotide reductase by time-resolved physical biochemical methods and X-ray crystallography.
Biochemistry Volume: 37 Page(s): 5840 - 5848
04/28/1998 Authors: Tong W; Burdi D; Riggs-Gelasco P; Chen S; Edmondson D; Huynh BH; Stubbe J; Han S; Arvai A; Tainer J -
Reaction of Escherichia coli cytochrome bo3 with substoichiometric ubiquinol-2: a freeze-quench electron paramagnetic resonance investigation.
Biochemistry Volume: 37 Page(s): 4160 - 4168
03/24/1998 Authors: Schultz BE; Edmondson DE; Chan SI -
The recombinant alpha subunit of glutamate synthase: spectroscopic and catalytic properties.
Biochemistry Volume: 37 Page(s): 1828 - 1838
02/17/1998 Authors: Vanoni MA; Fischer F; Ravasio S; Verzotti E; Edmondson DE; Hagen WR; Zanetti G; Curti B -
Electron injection through a specific pathway determines the outcome of oxygen activation at the diiron cluster in the F208Y mutant of Escherichia coli ribonucleotide reductase protein R2.
Biochemistry Volume: 37 Page(s): 1124 - 1130
01/27/1998 Authors: Parkin SE; Chen S; Ley BA; Mangravite L; Edmondson DE; Huynh BH; Bollinger JM -
Rapid formation of a semiquinone species on oxidation of quinol by the cytochrome bo(3) oxidase from Escherichia coli
Volume: 1 Page(s): 33 - 39
01/01/1998 Authors: Osborne JP; Musser SM; Schultz BE; Edmondson DE; Chan SI; Gennis RB -
Characterization of a diiron(III) peroxo intermediate in the reaction cycle of methane monooxygenase hydroxylase from Methylococcus capsulatus (Bath) (vol 117, pg 4997, 1995)
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY Volume: 119 Page(s): 11134 - 11134
11/12/1997 Authors: Liu KE; Valentine AM; Qiu D; Edmondson DE; Appelman EH; Spiro TG; Lippard SJ -
Rapid and parallel formation of Fe3+ multimers, including a trimer, during H-type subunit ferritin mineralization.
Biochemistry Volume: 36 Page(s): 7917 - 7927
06/24/1997 Authors: Pereira AS; Tavares P; Lloyd SG; Danger D; Edmondson DE; Theil EC; Huynh BH -
Mossbauer spectroscopic and kinetic characterization of ferric clusters formed in h-chain ferritin mineralization.
Volume: 213 Page(s): 503 - INOR
04/13/1997 Authors: Tavares P; Pereira AS; Lloyd SG; Danger D; Edmondson DE; Theil EC; Huynh BH -
From the mass production of Methylococcus capsulatus to the efficient separation and isolation of methane monooxygenase proteins. Characterization of novel intermediates in substrate reactions of methane monooxygenase.
Volume: 26 Page(s): 273 - 286
01/01/1997 Authors: Liu KE; Valentine AM; Wang DL; Huynh BH; Edmondson DE; Salifoglou A; Lippard SJ -
Purification and characterization of a prokaryotic xanthine dehydrogenase from Comamonas acidovorans.
Biochemistry Volume: 35 Page(s): 5441 - 5450
04/30/1996 Authors: Xiang Q; Edmondson DE -
Sarcosine oxidase contains a novel covalently bound FMN.
Biochemistry Volume: 35 Page(s): 5292 - 5299
04/23/1996 Authors: Willie A; Edmondson DE; Jorns MS -
Aminium cation radical mechanism proposed for monoamine oxidase B catalysis: are there alternatives?
Xenobiotica Volume: 25 Page(s): 735 - 753
07/01/1995 Authors: Edmondson DE -
SEQUENCE SIMILARITIES OF PSEUDOMONAS ACIDOVORANS XANTHINE DEHYDROGENASE WITH THOSE FROM EUKARYOTES
Volume: 9 Page(s): A1358 - A1358
04/24/1995 Authors: XIANG Q; EDMONDSON DE -
Structure activity studies of the substrate binding site in monoamine oxidase B.
Biochimie Volume: 77 Page(s): 643 - 650
01/01/1995 Authors: Edmondson DE -
Use of rapid kinetics methods to study the assembly of the diferric-tyrosyl radical cofactor of E. coli ribonucleotide reductase.
Methods Enzymol Volume: 258 Page(s): 278 - 303
01/01/1995 Authors: Bollinger JM; Tong WH; Ravi N; Huynh BH; Edmondson DE; Stubbe JA -
Hydrogen tunneling in the flavoenzyme monoamine oxidase B.
Biochemistry Volume: 33 Page(s): 14871 - 14878
12/13/1994 Authors: Jonsson T; Edmondson DE; Klinman JP -
Flavin substrate specificity of the vitamin B2-aldehyde-forming enzyme from Schizophyllum commune.
Arch Biochem Biophys Volume: 315 Page(s): 100 - 103
11/15/1994 Authors: Kekelidze TN; Edmondson DE; McCormick DB -
Kinetic studies on the electron-transfer reaction between cytochrome c3 and flavodoxin from Desulfovibrio vulgaris strain Hildenborough.
Biochemistry Volume: 33 Page(s): 10386 - 10392
08/30/1994 Authors: De Francesco R; Edmondson DE; Moura I; Moura JJ; LeGall J -
Structure-activity relationships in the oxidation of benzylamine analogues by bovine liver mitochondrial monoamine oxidase B.
Biochemistry Volume: 33 Page(s): 7088 - 7098
06/14/1994 Authors: Walker MC; Edmondson DE -
FLAVIN SPECIFICITY OF THE VITAMIN-B(2)-ALDEHYDE FORMING ENZYME IN SCHIZOPHYLLUM-COMMUNE
Volume: 8 Page(s): A1422 - A1422
04/19/1994 Authors: KEKELIDZE TN; EDMONDSON DE; MCCORMICK DB -
PURIFICATION AND PROPERTIES OF XANTHINE DEHYDROGENASE FROM PSEUDOMONAS-ACIDOVORANS
Volume: 8 Page(s): A1422 - A1422
04/19/1994 Authors: XIANG O; EDMONDSON DE -
Quantitative structure-activity relationships in the oxidation of benzylamine analogues by bovine liver monoamine oxidase B
Page(s): 109 - 115
01/01/1994 Authors: Walker MC; Edmondson DE -
Studies on the induction and phosphorylation of xanthine dehydrogenase in cultured chick embryo hepatocytes.
Eur J Biochem Volume: 215 Page(s): 307 - 314
07/15/1993 Authors: Schieber A; Edmondson DE -
Spectral and kinetic studies of imine product formation in the oxidation of p-(N,N-dimethylamino)benzylamine analogues by monoamine oxidase B.
Biochemistry Volume: 32 Page(s): 5196 - 5202
05/18/1993 Authors: Edmondson DE; Bhattacharyya AK; Walker MC -
Resonance Raman spectroscopic evidence for an anionic flavin semiquinone in bovine liver monoamine oxidase.
Arch Biochem Biophys Volume: 300 Page(s): 178 - 185
01/01/1993 Authors: Yue KT; Bhattacharyya AK; Zhelyaskov VR; Edmondson DE -
Role of phospholipase D-derived diradylglycerol in the activation of the human neutrophil respiratory burst oxidase. Inhibition by phosphatidic acid phosphohydrolase inhibitors.
J Immunol Volume: 149 Page(s): 2749 - 2758
10/15/1992 Authors: Perry DK; Hand WL; Edmondson DE; Lambeth JD -
Characterization of the flavins and the iron-sulfur centers of glutamate synthase from Azospirillum brasilense by absorption, circular dichroism, and electron paramagnetic resonance spectroscopies.
Biochemistry Volume: 31 Page(s): 4613 - 4623
05/19/1992 Authors: Vanoni MA; Edmondson DE; Zanetti G; Curti B -
Riboflavin 5'-pyrophosphate: a contaminant of commercial FAD, a coenzyme for FAD-dependent oxidases, and an inhibitor of FAD synthetase.
Anal Biochem Volume: 202 Page(s): 348 - 355
05/01/1992 Authors: Hartman HA; Edmondson DE; McCormick DB -
Effect of KCl on the interactions between NADPH:cytochrome P-450 reductase and either cytochrome c, cytochrome b5 or cytochrome P-450 in octyl glucoside micelles.
Eur J Biochem Volume: 204 Page(s): 1075 - 1082
03/15/1992 Authors: Nisimoto Y; Edmondson DE -
INHIBITION OF PHOSPHATIDIC-ACID (PA) PHOSPHOHYDROLASE BLOCKS PHORBOL ESTER-STIMULATED SUPEROXIDE GENERATION IN HUMAN NEUTROPHILS
Volume: 6 Page(s): A1923 - A1923
02/28/1992 Authors: PERRY D; HAND WL; EDMONDSON DE -
ESR STUDIES OF THE FE/S CENTERS OF AZOSPIRILLUM-BRASILENSE GLUTAMATE SYNTHASE
Volume: 6 Page(s): A191 - A191
01/01/1992 Authors: EDMONDSON DE; VANONI MA; CURTI B; ZANETTI G -
RESONANCE RAMAN-SPECTROSCOPIC EVIDENCE FOR AN ANIONIC FLAVIN SEMIQUINONE IN BEEF-LIVER MONOAMINE-OXIDASE
Volume: 6 Page(s): A319 - A319
01/01/1992 Authors: ZHELYASKOV VR; BHATTACHARYYA AK; EDMONDSON DE; YUE KT -
INVIVO PHOSPHORYLATION OF CHICKEN LIVER XANTHINE DEHYDROGENASE
Volume: 6 Page(s): A190 - A190
01/01/1992 Authors: SCHIEBER A; EDMONDSON DE -
Mechanistic studies on Azospirillum brasilense glutamate synthase.
Biochemistry Volume: 30 Page(s): 11478 - 11484
12/03/1991 Authors: Vanoni MA; Edmondson DE; Rescigno M; Zanetti G; Curti B -
MECHANISM OF ASSEMBLY OF THE DINUCLEAR IRON CENTER - TYROSYL RADICAL COFACTOR OF RIBONUCLEOTIDE REDUCTASE
Volume: 202 Page(s): 22 - BIOL
08/25/1991 Authors: STUBBE J; BOLLINGER M; EDMONDSON DE; HUYNH BH; FILLEY J; NORTON J -
Mechanism of assembly of the tyrosyl radical-dinuclear iron cluster cofactor of ribonucleotide reductase.
Science Volume: 253 Page(s): 292 - 298
07/19/1991 Authors: Bollinger JM; Edmondson DE; Huynh BH; Filley J; Norton JR; Stubbe J -
Kinetic comparison of reduction and intramolecular electron transfer in milk xanthine oxidase and chicken liver xanthine dehydrogenase by laser flash photolysis.
Biochemistry Volume: 30 Page(s): 5912 - 5917
06/18/1991 Authors: Walker MC; Hazzard JT; Tollin G; Edmondson DE -
Light-dependent de-activation/re-activation of Anabaena variabilis ferredoxin: NADP+ reductase.
Biochem J Volume: 274 ( Pt 3) Page(s): 781 - 786
03/15/1991 Authors: Fillat MF; Edmondson DE; Gomez-Moreno C -
GLUTAMATE SYNTHASE FROM AZOSPIRILLUM-BRASILENSE - ROLE OF FLAVINS AND IRON SULFUR CENTERS
Page(s): 749 - 753
01/01/1991 Authors: VANONI MA; ZANETTI G; CURTI B; EDMONDSON DE -
ELECTRON-SPIN-RESONANCE SPECTRAL STUDIES OF N-15-H-2 FLAVIN COENZYME SEMIQUINONES IN FLAVOENZYMES
Page(s): 67 - 72
01/01/1991 Authors: EDMONDSON DE; MULLER F; SCHAUB F; NISIMOTO Y -
COVALENT PHOSPHORUS GROUPS IN FLAVOPROTEINS - THE PHOSPHODIESTER LINKAGE IN AZOTOBACTER (OP) FLAVODOXIN
Page(s): 385 - 391
01/01/1991 Authors: EDMONDSON DE; BOYLAN M; TAYLOR M -
EVIDENCE FOR PARTICIPATION OF THE PHOSPHOSERYL RESIDUE OF XANTHINE-OXIDASE IN THE HYDROXYLATION EVENT DURING ENZYME CATALYSIS
Page(s): 685 - 689
01/01/1991 Authors: DARDENNE SC; EDMONDSON DE -
Kinetic isotope effect studies on milk xanthine oxidase and on chicken liver xanthine dehydrogenase.
Biochemistry Volume: 29 Page(s): 9046 - 9052
09/25/1990 Authors: D'Ardenne SC; Edmondson DE -
Structural and chemical properties of a flavodoxin from Anabaena PCC 7119.
Biochim Biophys Acta Volume: 1040 Page(s): 301 - 307
09/03/1990 Authors: Fillat MF; Edmondson DE; Gomez-Moreno C -
Azotobacter vinelandii flavodoxin: purification and properties of the recombinant, dephospho form expressed in Escherichia coli.
Biochemistry Volume: 29 Page(s): 6911 - 6918
07/24/1990 Authors: Taylor MF; Boylan MH; Edmondson DE -
A 31P-nuclear-magnetic-resonance study of NADPH-cytochrome-P-450 reductase and of the Azotobacter flavodoxin/ferredoxin-NADP+ reductase complex.
Eur J Biochem Volume: 190 Page(s): 531 - 537
07/05/1990 Authors: Bonants PJ; Mller F; Vervoort J; Edmondson DE -
Studies on the incorporation of a covalently bound disubstituted phosphate residue into Azotobacter vinelandii flavodoxin in vivo.
Biochem J Volume: 268 Page(s): 745 - 749
06/15/1990 Authors: Boylan MH; Edmondson DE -
Preparation and properties of a cross-linked complex between ferredoxin--NADP+ reductase and flavodoxin.
Eur J Biochem Volume: 183 Page(s): 539 - 544
08/15/1989 Authors: Pueyo JJ; Sancho J; Edmondson DE; Gmez-Moreno C -
Electron-nuclear double resonance spectroscopy of the desulfo-inhibited molybdenum(V) center in bovine milk xanthine oxidase.
Biochemistry Volume: 28 Page(s): 5924 - 5930
07/11/1989 Authors: Edmondson DE; D'Ardenne SC -
Effect of hypoxia on tert-butylhydroperoxide-induced oxidative injury in hepatocytes.
Mol Pharmacol Volume: 34 Page(s): 413 - 420
09/01/1988 Authors: Tribble DL; Jones DP; Edmondson DE -
pKa values of the 8 alpha-imidazole substituents in selected flavoenzymes containing 8 alpha-histidylflavins.
Arch Biochem Biophys Volume: 264 Page(s): 281 - 287
07/01/1988 Authors: De Francesco R; Edmondson DE -
Oxidation-reduction potential studies on p-hydroxybenzoate hydroxylase from Pseudomonas fluorescens.
Biochim Biophys Acta Volume: 953 Page(s): 258 - 262
04/14/1988 Authors: Williamson G; Edmondson DE; Mller F -
INVIVO STUDIES OF AZOTOBACTER FLAVODOXIN PHOSPHORYLATION
Volume: 2 Page(s): A355 - A355
03/15/1988 Authors: BOYLAN M; EDMONDSON DE -
PROTON-DETECTED H-1-P-31 2D NMR-SPECTROSCOPY OF AZOTOBACTER FLAVODOXIN - EVIDENCE FOR A PHOSPHODIESTER LINKAGE BETWEEN A SERYL AND A THREONYL RESIDUE
Volume: 2 Page(s): A355 - A355
03/15/1988 Authors: EDMONDSON DE; LIVE D -
PULSED ELECTRON-PARAMAGNETIC-RES STUDIES OF THE FMN NEUTRAL SEMIQUINONE OF AZOTOBACTER FLAVODOXIN
Volume: 2 Page(s): A354 - A354
03/15/1988 Authors: DEFRANCESCO R; EDMONDSON DE; MCCRACKEN J; PEISACH J -
KINETIC-STUDIES OF C-H BOND-CLEAVAGE IN THE CATALYTIC MECHANISM OF XANTHINE-OXIDASE
Volume: 2 Page(s): A587 - A587
03/15/1988 Authors: DARDENNE S; EDMONDSON DE -
Purification and properties of ferredoxin-NADP+ oxidoreductase from the nitrogen-fixing cyanobacteria Anabaena variabilis.
Arch Biochem Biophys Volume: 260 Page(s): 200 - 207
01/01/1988 Authors: Sancho J; Peleato ML; Gomez-Moreno C; Edmondson DE -
Flavodoxin-cytochrome c interactions: circular dichroism and nuclear magnetic resonance studies.
Biochemistry Volume: 26 Page(s): 5042 - 5048
08/11/1987 Authors: Tollin G; Brown K; De Francesco R; Edmondson DE -
Influence of 8 alpha-imidazole substitution of the FMN cofactor on the rate of electron transfer from the neutral semiquinones of two flavodoxins to cytochrome c.
Biochemistry Volume: 26 Page(s): 5036 - 5042
08/11/1987 Authors: De Francesco R; Tollin G; Edmondson DE -
EFFECT OF THE LABILE PHOSPHORUS GROUP ON THE INTERACTIONS OF AZOTOBACTER FLAVODOXIN WITH FERREDOXIN-NADP+ OXIDOREDUCTASE FROM ANABAENA-VARIABILIS
Volume: 45 Page(s): 1888 - 1888
05/01/1986 Authors: SANCHO J; PELEATO ML; GOMEZMORENO C; EDMONDSON DE -
ANDROST-5-ENE-3-BETA-OL-17-BETA-SULFATE - A WATER-SOLUBLE SUBSTRATE FOR CHOLESTEROL OXIDASE
Volume: 45 Page(s): 1888 - 1888
05/01/1986 Authors: EDMONDSON DE; BAKER KH; WILLIAMSON G; JACKSON K; GOLDSMITH DJ -
INFLUENCE OF THE SIDE-CHAIN PHOSPHATE ON THE BINDING OF REDUCED FLAVIN TO AZOTOBACTER APOFLAVODOXIN
Volume: 49 Page(s): A500 - A500
02/01/1986 Authors: EDMONDSON DE; WILLIAMSON G -
1H NMR spectral analysis of the ribityl side chain of riboflavin and its ring-substituted analogs.
Methods Enzymol Volume: 122 Page(s): 240 - 248
01/01/1986 Authors: Williamson G; Edmondson DE -
H-1-NMR SPECTRAL-ANALYSIS OF THE RIBITYL SIDE-CHAIN OF RIBOFLAVIN AND ITS RING-SUBSTITUTED ANALOGS
METHODS IN ENZYMOLOGY Volume: 122 Page(s): 240 - 248
01/01/1986 Authors: WILLIAMSON G; EDMONDSON DE -
Proton nuclear magnetic resonance studies of 8 alpha-N-imidazolylriboflavin in its oxidized and reduced forms.
Biochemistry Volume: 24 Page(s): 7918 - 7926
12/31/1985 Authors: Williamson G; Edmondson DE -
Effect of pH on oxidation-reduction potentials of 8 alpha-N-imidazole-substituted flavins.
Biochemistry Volume: 24 Page(s): 7790 - 7797
12/17/1985 Authors: Williamson G; Edmondson DE -
Electron-spin-resonance studies on flavoenzymes.
Biochem Soc Trans Volume: 13 Page(s): 593 - 600
06/01/1985 Authors: Edmondson DE -
Evidence for an aldehyde intermediate in the catalytic mechanism of thiamine oxidase.
Arch Biochem Biophys Volume: 239 Page(s): 46 - 52
05/15/1985 Authors: Gomez-Moreno C; Edmondson DE -
N-nitrosodialkylamines do not function as substrates for liver monoamine oxidase.
Proc Natl Acad Sci U S A Volume: 82 Page(s): 682 - 683
02/01/1985 Authors: Edmondson DE; Bruice TC -
H-1-NMR SPECTRAL-ANALYSIS OF THE RIBITYL SIDE-CHAIN OF VARIOUS RIBOFLAVIN ANALOGS
Volume: 44 Page(s): 1211 - 1211
01/01/1985 Authors: WILLIAMSON G; EDMONDSON DE -
31P nuclear magnetic resonance and chemical studies of the phosphorus residues in bovine milk xanthine oxidase.
Eur J Biochem Volume: 145 Page(s): 237 - 243
12/03/1984 Authors: Davis MD; Edmondson DE; Mller F -
Evidence for two copper atoms/subunit in dopamine beta-monooxygenase catalysis.
J Biol Chem Volume: 259 Page(s): 3399 - 3402
03/25/1984 Authors: Klinman JP; Krueger M; Brenner M; Edmondson DE -
Biochemistry.
Science Volume: 219 Page(s): 1317
03/18/1983 Authors: Edmondson DE -
Kinetic properties of pyridoxamine (pyridoxine)-5'-phosphate oxidase from rabbit liver.
J Biol Chem Volume: 258 Page(s): 840 - 845
01/25/1983 Authors: Choi JD; Bowers-Komro M; Davis MD; Edmondson DE; McCormick DB -
Semiquinone formation in flavo- and metalloflavoproteins.
Top Curr Chem Volume: 108 Page(s): 109 - 138
01/01/1983 Authors: Edmondson DE; Tollin G -
INTRAMOLECULAR ELECTRON-TRANSFER IN XANTHINE-OXIDASE
Volume: 41 Page(s): A392 - A392
01/01/1983 Authors: BHATTACHARYYA A; TOLLIN G; DAVIS M; EDMONDSON DE -
The role of the membrane in the regulation of activity of microsomal glucose-6-phosphatase.
J Biol Chem Volume: 257 Page(s): 1145 - 1148
02/10/1982 Authors: Zakim D; Edmondson DE -
Kinetic studies on the catalytic mechanism of liver monoamine oxidase.
Biochemistry Volume: 21 Page(s): 595 - 600
02/02/1982 Authors: Husain M; Edmondson DE; Singer TP -
CATALYTIC PROPERTIES OF OXIDASES CONTAINING COVALENTLY BOUND FLAVIN COENZYMES
Volume: 184 Page(s): 2 - BIOL
01/01/1982 Authors: EDMONDSON DE -
8 alpha-(O-Tyrosyl)flavin adenine dinucleotide, the prosthetic group of bacterial p-cresol methylhydroxylase.
Biochemistry Volume: 20 Page(s): 3068 - 3075
05/26/1981 Authors: McIntire W; Edmondson DE; Hopper DJ; Singer TP -
Identification of neutral and anionic 8 alpha-substituted flavin semiquinones in flavoproteins by electron spin resonance spectroscopy.
Arch Biochem Biophys Volume: 208 Page(s): 69 - 74
04/15/1981 Authors: Edmondson DE; Ackrell BA; Kearney EB -
Glucose oxidase contains a disubstituted phosphorus residue. Phosphorus-31 nuclear magnetic resonance studies of the flavin and nonflavin phosphate residues.
Biochemistry Volume: 20 Page(s): 617 - 621
02/03/1981 Authors: James TL; Edmondson DE; Husain M -
Formation and mode of action of flavoproteins.
Annu Rev Nutr Volume: 1 Page(s): 281 - 317
01/01/1981 Authors: Merrill AH; Lambeth JD; Edmondson DE; McCormick DB -
Suicide inhibitors of central nervous system enzymes.
Essays Neurochem Neuropharmacol Volume: 5 Page(s): 131 - 153
01/01/1981 Authors: Singer TP; Edmondson DE; Salach JI -
8 alpha-O-Tyrosyl-FAD: a new form of covalently bound flavin from p-cresol methylhydroxylase.
J Biol Chem Volume: 255 Page(s): 6553 - 6555
07/25/1980 Authors: McIntire W; Edmondson DE; Singer TP; Hopper DJ -
Structure, properties, and determination of covalently bound flavins.
Methods Enzymol Volume: 66 Page(s): 253 - 264
01/01/1980 Authors: Singer TP; Edmondson DE -
DEMONSTRATION OF A NEW TYPE OF COVALENT FLAVIN IN P-CRESOL-METHYLHYDROXYLASE
Volume: 39 Page(s): 1698 - 1698
01/01/1980 Authors: MCINTIRE W; EDMONDSON DE; SINGER TP; HOPPER DJ -
KINETIC-STUDIES ON THE MECHANISM OF LIVER MONOAMINE-OXIDASE
Volume: 180 Page(s): 55 - BIOL
01/01/1980 Authors: HUSAIN M; EDMONDSON DE; SINGER TP -
P-31 NMR-STUDIES ON THE FLAVIN AND NON-FLAVIN PHOSPHATES OF GLUCOSE-OXIDASE
Volume: 39 Page(s): 1119 - 1119
01/01/1980 Authors: JAMES TL; EDMONDSON DE; HUSAI M -
Purification and properties of the bacterial flavoprotein: thiamin dehydrogenase.
J Biol Chem Volume: 254 Page(s): 7630 - 7635
08/25/1979 Authors: Gomez-Moreno C; Choy M; Edmondson DE -
Covalently bound non-coenzyme phosphorus residues in flavoproteins: 31P nuclear magnetic resonance studies of Azotobacter flavodoxin.
Proc Natl Acad Sci U S A Volume: 76 Page(s): 3786 - 3789
08/01/1979 Authors: Edmondson DE; James TL -
Inactivation of succinate dehydrogenase by 3-nitropropionate.
J Biol Chem Volume: 254 Page(s): 5161 - 5167
06/25/1979 Authors: Coles CJ; Edmondson DE; Singer TP -
Identification of the covalently-bound flavin of L-galactonolactone oxidase from yeast.
FEBS Lett Volume: 97 Page(s): 40 - 42
01/01/1979 Authors: Kenney WC; Edmondson DE; Singer TP; Nishikimi M; Noguchi E; Yagi K -
Flavoproteins (overview).
Methods Enzymol Volume: 53 Page(s): 397 - 418
01/01/1978 Authors: Singer TP; Edmondson DE -
Synthesis and isolation of 8 alpha-substituted flavins and flavin peptides.
Methods Enzymol Volume: 53 Page(s): 449 - 465
01/01/1978 Authors: Edmondson DE; Kenney WC; Singer TP -
Reversible inactivation of L-amino acid oxidase. Properties of the three conformational forms.
J Biol Chem Volume: 252 Page(s): 8035 - 8039
11/25/1977 Authors: Coles CJ; Edmondson DE; Singer TP -
2',5'-Anhydro-8alpha-histidylflavins: their formation and structural elucidation.
Biochemistry Volume: 16 Page(s): 4308 - 4311
09/20/1977 Authors: Edmondson DE -
The effect of 8alpha-substitution on flavin triplet state and semiquinone properties as investigated by flash photolysis.
Photochem Photobiol Volume: 25 Page(s): 445 - 450
05/01/1977 Authors: Edmondson DE; Rizzuto F; Tollin G -
Identification and properties of the covalently bound flavin of beta-cyclopiazonate oxidocyclase.
Biochemistry Volume: 15 Page(s): 4931 - 4935
11/02/1976 Authors: Kenney WC; Edmondson DE; Singer TP; Steenkamp DJ; Schabort JC -
Identification of the covalently bound flavin of thiamin dehydrogenase.
J Biol Chem Volume: 251 Page(s): 5386 - 5390
09/10/1976 Authors: Kenney WC; Edmondson DE; Seng RL -
Identification of the covalently bound flavin of L-gulono-gamma-lactone oxidase.
Biochem Biophys Res Commun Volume: 71 Page(s): 1194 - 1200
08/23/1976 Authors: Kenney WC; Edmondson DE; Singer TP -
Structural elucidation and properties of 8alpha-(N1-histidyl)riboflavin: the flavin component of thiamine dehydrogenase and beta-cyclopiazonate oxidocyclase.
Biochemistry Volume: 15 Page(s): 2937 - 2945
07/13/1976 Authors: Edmondson DE; Kenney WC; Singer TP -
8alpha-substituted flavins of biological importance: an updating.
FEBS Lett Volume: 64 Page(s): 255 - 265
05/01/1976 Authors: Edmondson DE; Singer TP -
Identification and properties of 8alpha-(N(1)-histidyl)-riboflavin: the flavin component of thiamine dehydrogenase and beta-cyclopiazonate oxidocyclase.
Biochem Biophys Res Commun Volume: 68 Page(s): 242 - 248
01/12/1976 Authors: Edmondson DE; Kenney WC -
2',5'-ANHYDRO-8-ALPHA-HISTIDYL FLAVINS - THEIR OCCURRENCE AND STRUCTURAL ELUCIDATION
Volume: 35 Page(s): 1542 - 1542
01/01/1976 Authors: EDMONDSON DE -
IDENTIFICATION OF STRUCTURE OF COVALENTLY BOUND FLAVIN COENZYME OF THIAMINE DEHYDROGENASE AND BETA-CYCLOPIAZONATE OXIDOCYCLASE
Volume: 35 Page(s): 1542 - 1542
01/01/1976 Authors: KENNEY WC; EDMONDSON DE -
2',5'-ANHYDRO-8-ALPHA-HISTIDYL FLAVINS - THEIR OCCURRENCE AND STRUCTURAL ELUCIDATION
Volume: 172 Page(s): 147 - 147
01/01/1976 Authors: EDMONDSON DE -
Mechanism of the reductive activation of succinate dehydrogenase.
J Biol Chem Volume: 250 Page(s): 7114 - 7119
09/25/1975 Authors: Ackrell BA; Kearney EB; Edmondson D -
The covalently bound flavin of Chromatium cytochrome c552. 2. Sequence of flavin peptides and flavin-tyrosine interaction.
Eur J Biochem Volume: 48 Page(s): 449 - 453
10/02/1974 Authors: Kenney WC; Edmondson DE; Singer TP -
The covalently bound flavin of Chromatium cytochrome c552. 1. Evidence for cysteine thiohemiacetal at the 8 alpha position.
Eur J Biochem Volume: 48 Page(s): 439 - 448
10/02/1974 Authors: Walker WH; Kenney WC; Edmondson DE; Singer TP; Cronin JR; Hendriks R -
Intramolecular hemiacetal formation in 8-formylriboflavine.
Biochemistry Volume: 13 Page(s): 2817 - 2821
07/02/1974 Authors: Edmondson DE -
8 alpha-substituted flavins of biological importance.
FEBS Lett Volume: 42 Page(s): 1 - 14
05/15/1974 Authors: Singer TP; Edmondson DE -
The covalently bound flavin prosthetic group of beta-cyclopiazonate oxidocyclase.
FEBS Lett Volume: 41 Page(s): 111 - 114
04/15/1974 Authors: Kenney WC; Edmondson DE; Singer TP; Steenkamp DJ; Schabort JC -
A novel form of covalently bound flavin from thiamine dehydrogenase.
Biochem Biophys Res Commun Volume: 57 Page(s): 106 - 111
03/15/1974 Authors: Kenney WC; Edmondson DE; Singer TP -
Oxidation-reduction properties of the 8 alpha-substituted flavins.
J Biol Chem Volume: 248 Page(s): 8144 - 8149
12/10/1973 Authors: Edmondson DE; Singer TP -
Kinetic studies on the substrate reduction of xanthine oxidase.
J Biol Chem Volume: 248 Page(s): 6135 - 6144
09/10/1973 Authors: Edmondson D; Ballou D; Van Heuvelen A; Palmer G; Massey V -
Structure of the flavin site of Chromatium flavocytochrome c -552 .
Biochem Biophys Res Commun Volume: 52 Page(s): 434 - 439
05/15/1973 Authors: Kenney WC; Edmondson D; Seng R; Singer TP -
The separation of functional and non-functional xanthine oxidase by affinity chromatography.
Biochem J Volume: 127 Page(s): 10P - 11P
04/01/1972 Authors: Massey V; Edmondson D; Palmer G; Beacham LM; Elion GB -
On the importance of the N-5 position in flavin coenzymes. Properties of free and protein-bound 5-deaza analogs.
Biochemistry Volume: 11 Page(s): 1133 - 1138
03/28/1972 Authors: Edmondson DE; Barman B; Tollin G -
The resolution of active and inactive xanthine oxidase by affinity chromatography.
J Biol Chem Volume: 247 Page(s): 1597 - 1604
03/10/1972 Authors: Edmondson D; Massey V; Palmer G; Beacham LM; Elion GB -
The isolation and characterization of Rhodospirillum rubrum flavodoxin.
Biochem Biophys Res Commun Volume: 45 Page(s): 327 - 336
10/15/1971 Authors: Cusanovich MA; Edmondson DE -
Flavin-protein interactions and the redox properties of the Shethna flavoprotein.
Biochemistry Volume: 10 Page(s): 133 - 145
01/05/1971 Authors: Edmondson DE; Tollin G -
Chemical and physical characterization of the Shethna flavoprotein and apoprotein and kinetics and thermodynamics of flavin analog binding to the apoprotein.
Biochemistry Volume: 10 Page(s): 124 - 132
01/05/1971 Authors: Edmondson DE; Tollin G -
Circular dichroism studies of the flavin chromophore and of the relation between redox properties and flavin environment in oxidases and dehydrogenases.
Biochemistry Volume: 10 Page(s): 113 - 124
01/05/1971 Authors: Edmondson DE; Tollin G -
On the mechanism of inactivation of xanthine oxidase by cyanide.
J Biol Chem Volume: 245 Page(s): 6595 - 6598
12/25/1970 Authors: Massey V; Edmondson D