Publications

• SARS-CoV-2-specific plasma cells are not durably established in the bone marrow long-lived compartment after mRNA vaccination.
  Nat Med Volume: 31 Page(s): 235 - 244
  01/01/2025 Authors: Nguyen DC; Hentenaar IT; Morrison-Porter A; Solano D; Haddad NS; Castrillon C; Runnstrom MC; Lamothe PA; Andrews J; Roberts D
• scRNA-seq profiling of human granulocytes reveals expansion of developmentally flexible neutrophil precursors with mixed neutrophil and eosinophil properties in asthma.
  J Leukoc Biol Volume: 116 Page(s): 1184 - 1197
  11/04/2024 Authors: Haruna N-F; Politanska Y; Connelly AR; O'Connor K; Bhattacharya S; Miklaszewski GE; Prez-Leonor XG; Rerko G; Hentenaar IT; Nguyen DC
• Natural malaria infection elicits rare but potent neutralizing antibodies to the blood-stage antigen RH5.
  Cell Volume: 187 Page(s): 4981 - 4995.e14
  09/05/2024 Authors: Wang LT; Cooper AJR; Farrell B; Miura K; Diouf A; Mller-Sienerth N; Crosnier C; Purser L; Kirtley PJ; Maciuszek M
• Patients taking benralizumab, dupilumab, or mepolizumab have lower postvaccination SARS-CoV-2 immunity.
  J Allergy Clin Immunol Volume: 154 Page(s): 435 - 446
  08/01/2024 Authors: Runnstrom MC; Lamothe PA; Faliti CE; Cheedarla N; Moreno A; Suthar MS; Nahata R; Ravindran M; Haddad NS; Morrison-Porter A
• MENSA, a Media Enriched with Newly Synthesized Antibodies, to Identify SARS-CoV-2 Persistence and Latent Viral Reactivation in Long-COVID.
  medRxiv
  07/07/2024 Authors: Haddad NS; Morrison-Porter A; Quehl H; Capric V; Lamothe PA; Anam F; Runnstrom MC; Truong AD; Dixit AN; Woodruff MC
• The Majority of SARS-CoV-2 Plasma Cells are Excluded from the Bone Marrow Long-Lived Compartment 33 Months after mRNA Vaccination.
  
  03/13/2024 Authors: Lee F; Nguyen D; Hentenaar I; Morrison-Porter A; Solano D; Haddad N; Castrillon C; Lamothe P; Andrews J; Roberts D
• The Majority of SARS-CoV-2 Plasma Cells are Excluded from the Bone Marrow Long-Lived Compartment 33 Months after mRNA Vaccination.
  
  03/05/2024 Authors: Nguyen DC; Hentenaar IT; Morrison-Porter A; Solano D; Haddad NS; Castrillon C; Lamothe PA; Andrews J; Roberts D; Lonial S
• Distinct transcriptomes and autocrine cytokines underpin maturation and survival of antibody-secreting cells in systemic lupus erythematosus.
  Nat Commun Volume: 15 Page(s): 1899
  03/01/2024 Authors: Chen W; Hong S-H; Jenks SA; Anam FA; Tipton CM; Woodruff MC; Hom JR; Cashman KS; Faliti CE; Wang X
• Majority of human circulating IgG plasmablasts stop blasting in a cell-free pro-survival culture.
  Sci Rep Volume: 14 Page(s): 3616
  02/13/2024 Authors: Nguyen DC; Saney C; Hentenaar IT; Cabrera-Mora M; Capric V; Woodruff MC; Andrews J; Lonial S; Sanz I; Lee FE-H
• Majority of human circulating plasmablasts stop blasting: A probable misnomer.
  bioRxiv
  09/13/2023 Authors: Nguyen DC; Saney C; Hentenaar IT; Cabrera-Mora M; Woodruff MC; Andrews J; Lonial S; Sanz I; Lee FE-H
• Understanding heterogeneity of human bone marrow plasma cell maturation and survival pathways by single-cell analyses.
  Cell Rep Volume: 42 Page(s): 112682
  07/25/2023 Authors: Duan M; Nguyen DC; Joyner CJ; Saney CL; Tipton CM; Andrews J; Lonial S; Kim C; Hentenaar I; Kosters A
• SLE Antibody-Secreting Cells Are Characterized by Enhanced Peripheral Maturation and Survival Programs.
  Res Sq
  06/27/2023 Authors: Chen W; Hong S-H; Jenks SA; Anam FA; Tipton CM; Woodruff MC; Hom JR; Cashman KS; Faliti CE; Wang X
• Human Bone Marrow Plasma Cell Atlas: Maturation and Survival Pathways Unraveled by Single Cell Analyses.
  bioRxiv
  01/20/2023 Authors: Duan M; Nguyen DC; Joyner CJ; Saney CL; Tipton CM; Andrews J; Lonial S; Kim C; Hentenaar I; Kosters A
• Dysregulated naive B cells and de novo autoreactivity in severe COVID-19.
  Nature Volume: 611 Page(s): 139 - 147
  11/01/2022 Authors: Woodruff MC; Ramonell RP; Haddad NS; Anam FA; Rudolph ME; Walker TA; Truong AD; Dixit AN; Han JE; Cabrera-Mora M
• COVID-19 and plasma cells: Is there long-lived protection?
  Immunol Rev Volume: 309 Page(s): 40 - 63
  08/01/2022 Authors: Nguyen DC; Lamothe PA; Woodruff MC; Saini AS; Faliti CE; Sanz I; Lee FE-H
• Response under pressure: deploying emerging technologies to understand B-cell-mediated immunity in COVID-19.
  Nat Methods Volume: 19 Page(s): 387 - 391
  04/01/2022 Authors: Woodruff MC; Nguyen DC; Faliti CE; Saini AS; Lee FE-H; Sanz I
• Generation of human long-lived plasma cells by developmentally regulated epigenetic imprinting.
  Life Sci Alliance Volume: 5
  03/01/2022 Authors: Joyner CJ; Ley AM; Nguyen DC; Ali M; Corrado A; Tipton C; Scharer CD; Mi T; Woodruff MC; Hom J
• Plasma cell survival: The intrinsic drivers, migratory signals, and extrinsic regulators.
  Immunol Rev Volume: 303 Page(s): 138 - 153
  09/01/2021 Authors: Nguyen DC; Duan M; Ali M; Ley A; Sanz I; Lee FE-H
• Heterofunctional Particles as Single Cell Sensors to Capture Secreted Immunoglobulins and Isolate Antigen-Specific Antibody Secreting Cells.
  Adv Healthc Mater Volume: 10 Page(s): e2001947
  08/01/2021 Authors: Ramirez K; Kyu S; Nguyen D; Han S-Y; Lee YL; Bradley J; Randall T; Sanz I; Lee FE-H; Sulchek T
• Relaxed peripheral tolerance drives broad de novo autoreactivity in severe COVID-19.
  medRxiv
  07/27/2021 Authors: Woodruff MC; Ramonell RP; Saini AS; Haddad NS; Anam FA; Rudolph ME; Bugrovsky R; Hom J; Cashman KS; Nguyen DC
• One-Stop Serum Assay Identifies COVID-19 Disease Severity and Vaccination Responses.
  Immunohorizons Volume: 5 Page(s): 322 - 335
  05/17/2021 Authors: Haddad NS; Nguyen DC; Kuruvilla ME; Morrison-Porter A; Anam F; Cashman KS; Ramonell RP; Kyu S; Saini AS; Cabrera-Mora M
• Elevated SARS-CoV-2 Antibodies Distinguish Severe Disease in Early COVID-19 Infection.
  bioRxiv
  12/06/2020 Authors: Haddad NS; Nguyen DC; Kuruvilla ME; Morrison-Porter A; Anam F; Cashman KS; Ramonell RP; Kyu S; Saini AS; Cabrera-Mora M
• Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19.
  Nat Immunol Volume: 21 Page(s): 1506 - 1516
  12/01/2020 Authors: Woodruff MC; Ramonell RP; Nguyen DC; Cashman KS; Saini AS; Haddad NS; Ley AM; Kyu S; Howell JC; Ozturk T
• Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein.
  Nat Med Volume: 26 Page(s): 1422 - 1427
  09/01/2020 Authors: Zost SJ; Gilchuk P; Chen RE; Case JB; Reidy JX; Trivette A; Nargi RS; Sutton RE; Suryadevara N; Chen EC
• Differential transcriptome and development of human peripheral plasma cell subsets.
  JCI Insight Volume: 4
  05/02/2019 Authors: Garimalla S; Nguyen DC; Halliley JL; Tipton C; Rosenberg AF; Fucile CF; Saney CL; Kyu S; Kaminski D; Qian Y
• Author Correction: Factors of the bone marrow microniche that support human plasma cell survival and immunoglobulin secretion.
  Nat Commun Volume: 10 Page(s): 372
  01/17/2019 Authors: Nguyen DC; Garimalla S; Xiao H; Kyu S; Albizua I; Galipeau J; Chiang K-Y; Waller EK; Wu R; Gibson G
• Factors Affecting Early Antibody Secreting Cell Maturation Into Long-Lived Plasma Cells.
  Front Immunol Volume: 10 Page(s): 2138
  01/01/2019 Authors: Nguyen DC; Joyner CJ; Sanz I; Lee FE-H
• Factors of the bone marrow microniche that support human plasma cell survival and immunoglobulin secretion.
  Nat Commun Volume: 9 Page(s): 3698
  09/12/2018 Authors: Nguyen DC; Garimalla S; Xiao H; Kyu S; Albizua I; Galipeau J; Chiang K-Y; Waller EK; Wu R; Gibson G
• Extracellular vesicles from bone marrow-derived mesenchymal stromal cells support ex vivo survival of human antibody secreting cells.
  J Extracell Vesicles Volume: 7 Page(s): 1463778
  01/01/2018 Authors: Nguyen DC; Lewis HC; Joyner C; Warren V; Xiao H; Kissick HT; Wu R; Galipeau J; Lee FE-H
• Microscale generation of cardiospheres promotes robust enrichment of cardiomyocytes derived from human pluripotent stem cells.
  Stem Cell Reports Volume: 3 Page(s): 260 - 268
  08/12/2014 Authors: Nguyen DC; Hookway TA; Wu Q; Jha R; Preininger MK; Chen X; Easley CA; Spearman P; Deshpande SR; Maher K
• Cynomolgus and pigtail macaque IgG subclasses: characterization of IGHG genes and computational analysis of IgG/Fc receptor binding affinity.
  Immunogenetics Volume: 66 Page(s): 361 - 377
  06/01/2014 Authors: Nguyen DC; Sanghvi R; Scinicariello F; Pulit-Penaloza J; Hill N; Attanasio R
• Seroprevalence of antibodies to avian influenza A (H5) and A (H9) viruses among market poultry workers, Hanoi, Vietnam, 2001.
  PLoS One Volume: 7 Page(s): e43948
  01/01/2012 Authors: Uyeki TM; Nguyen DC; Rowe T; Lu X; Hu-Primmer J; Huynh LP; Hang NLK; Katz JM
• Pendrin mediates uptake of perchlorate in a mammalian in vitro system.
  Chemosphere Volume: 84 Page(s): 1484 - 1488
  09/01/2011 Authors: Attanasio R; Scinicariello F; Blount BC; Valentin-Blasini L; Rogers KA; Nguyen DC; Murray HE
• Characterization and allelic polymorphisms of rhesus macaque (Macaca mulatta) IgG Fc receptor genes.
  Immunogenetics Volume: 63 Page(s): 351 - 362
  06/01/2011 Authors: Nguyen DC; Scinicariello F; Attanasio R
• 17-Estradiol restores antibody responses to an influenza vaccine in a postmenopausal mouse model.
  Vaccine Volume: 29 Page(s): 2515 - 2518
  03/21/2011 Authors: Nguyen DC; Masseoud F; Lu X; Scinicariello F; Sambhara S; Attanasio R
• Genetic analysis of avian influenza A viruses isolated from domestic waterfowl in live-bird markets of Hanoi, Vietnam, preceding fatal H5N1 human infections in 2004.
  Arch Virol Volume: 154 Page(s): 1249 - 1261
  01/01/2009 Authors: Jadhao SJ; Nguyen DC; Uyeki TM; Shaw M; Maines T; Rowe T; Smith C; Huynh LPT; Nghiem HK; Nguyen DHT
• Epidemiology of influenza in Hanoi, Vietnam, from 2001 to 2003.
  J Infect Volume: 55 Page(s): 58 - 63
  07/01/2007 Authors: Nguyen HLK; Saito R; Ngiem HK; Nishikawa M; Shobugawa Y; Nguyen DC; Hoang LT; Huynh LP; Suzuki H
• Cross-protective immunity in mice induced by live-attenuated or inactivated vaccines against highly pathogenic influenza A (H5N1) viruses.
  Vaccine Volume: 24 Page(s): 6588 - 6593
  11/10/2006 Authors: Lu X; Edwards LE; Desheva JA; Nguyen DC; Rekstin A; Stephenson I; Szretter K; Cox NJ; Rudenko LG; Klimov A
• Protection of mice and poultry from lethal H5N1 avian influenza virus through adenovirus-based immunization.
  J Virol Volume: 80 Page(s): 1959 - 1964
  02/01/2006 Authors: Gao W; Soloff AC; Lu X; Montecalvo A; Nguyen DC; Matsuoka Y; Robbins PD; Swayne DE; Donis RO; Katz JM
• Evolution of H5N1 avian influenza viruses in Asia.
  Emerg Infect Dis Volume: 11 Page(s): 1515 - 1521
  10/01/2005 Authors: World Health Organization Global Influenza Program Surveillance Network
• Avian influenza (H5N1) viruses isolated from humans in Asia in 2004 exhibit increased virulence in mammals.
  J Virol Volume: 79 Page(s): 11788 - 11800
  09/01/2005 Authors: Maines TR; Lu XH; Erb SM; Edwards L; Guarner J; Greer PW; Nguyen DC; Szretter KJ; Chen L-M; Thawatsupha P
• Isolation and characterization of avian influenza viruses, including highly pathogenic H5N1, from poultry in live bird markets in Hanoi, Vietnam, in 2001.
  J Virol Volume: 79 Page(s): 4201 - 4212
  04/01/2005 Authors: Nguyen DC; Uyeki TM; Jadhao S; Maines T; Shaw M; Matsuoka Y; Smith C; Rowe T; Lu X; Hall H