Chunhui Xu PhD
- Department of Pediatrics
Professor
- (404) 727-7774
- chunhui.xu@emory.edu
- PubMed
- Xu Lab
- Google Scholar
-
Emory University School of Medicine
Department of Pediatrics
Academic Appointment
- Professor, Department of Pediatrics, Emory University School of Medicine
- Program Faculty, Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University
- Faculty Member, Parker H. Petit Institute for Bioengineering and Bioscience
Education
Degrees
- PhD from University of Georgia
Research
Focus
- My research has focused on (1) growth of human pluripotent stem cells (hPSCs) and (2) differentiation and enrichment of cardiomyocytes from hPSCs. In both areas, we developed methods that have been commonly used by other investigators. I will further investigate hPSC-derived cardiomyocytes that are relevant to pediatric heart diseases.
Publications
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Spaceflight alters protein levels and gene expression associated with stress response and metabolic characteristics in human cardiac spheroids.
Biomaterials Volume: 317 Page(s): 123080
06/01/2025 Authors: Forghani P; Liu W; Wang Z; Ling Z; Takaesu F; Yang E; Tharp GK; Nielsen S; Doraisingam S; Countryman S -
Ethanol exposure during differentiation of human induced pluripotent stem cells reduces cardiomyocyte generation and alters metabolism.
Life Sci Volume: 364 Page(s): 123434
03/01/2025 Authors: Man K; Fu L; Lane A; Harris F; Reid O; Armand LC; Forghani P; Wu R; Faundez V; Brown LA -
High-speed optical imaging with sCMOS pixel reassignment.
Nat Commun Volume: 15 Page(s): 4598
05/30/2024 Authors: Mandracchia B; Zheng C; Rajendran S; Liu W; Forghani P; Xu C; Jia S -
Space microgravity increases expression of genes associated with proliferation and differentiation in human cardiac spheres.
NPJ Microgravity Volume: 9 Page(s): 88
12/09/2023 Authors: Hwang H; Rampoldi A; Forghani P; Li D; Fite J; Boland G; Maher K; Xu C -
AMPK activator-treated human cardiac spheres enhance maturation and enable pathological modeling.
Stem Cell Res Ther Volume: 14 Page(s): 322
11/08/2023 Authors: Li D; Armand LC; Sun F; Hwang H; Wolfson D; Rampoldi A; Liu R; Forghani P; Hu X; Yu W-M -
Optimal sparsity allows reliable system-aware restoration of fluorescence microscopy images.
Sci Adv Volume: 9 Page(s): eadg9245
09/01/2023 Authors: Mandracchia B; Liu W; Hua X; Forghani P; Lee S; Hou J; Nie S; Xu C; Jia S -
Chronic ethanol exposure induces mitochondrial dysfunction and alters gene expression and metabolism in human cardiac spheroids.
Alcohol Clin Exp Res (Hoboken) Volume: 47 Page(s): 643 - 658
04/01/2023 Authors: Hwang H; Liu R; Eldridge R; Hu X; Forghani P; Jones DP; Xu C -
Space microgravity improves proliferation of human iPSC-derived cardiomyocytes.
Stem Cell Reports Volume: 17 Page(s): 2272 - 2285
10/11/2022 Authors: Rampoldi A; Forghani P; Li D; Hwang H; Armand LC; Fite J; Boland G; Maxwell J; Maher K; Xu C -
Carfilzomib Treatment Causes Molecular and Functional Alterations of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
J Am Heart Assoc Volume: 10 Page(s): e022247
12/21/2021 Authors: Forghani P; Rashid A; Sun F; Liu R; Li D; Lee MR; Hwang H; Maxwell JT; Mandawat A; Wu R -
Chronic Ethanol Exposure Induces Deleterious Changes in Cardiomyocytes Derived from Human Induced Pluripotent Stem Cells.
Stem Cell Rev Rep Volume: 17 Page(s): 2314 - 2331
12/01/2021 Authors: Liu R; Sun F; Armand LC; Wu R; Xu C