Publications

• Encoding of speech modes and loudness in ventral precentral gyrus.
  bioRxiv
  05/31/2025 Authors: Srinivasan A; Wairagkar M; Iacobacci C; Hou X; Card NS; Jacques BG; Pritchard AL; Bechefsky PH; Hochberg LR; AuYong N
• Pseudo-linear summation explains neural geometry of multi-finger movements in human premotor cortex.
  Nat Commun Volume: 16 Page(s): 5008
  05/30/2025 Authors: Shah NP; Avansino D; Kamdar F; Nicolas C; Kapitonava A; Vargas-Irwin C; Hochberg LR; Pandarinath C; Shenoy KV; Willett FR
• Stabilizing brain-computer interfaces through alignment of latent dynamics.
  Nat Commun Volume: 16 Page(s): 4662
  05/19/2025 Authors: Karpowicz BM; Ali YH; Wimalasena LN; Sedler AR; Keshtkaran MR; Bodkin K; Ma X; Rubin DB; Williams ZM; Cash SS
• Computation-through-Dynamics Benchmark: Simulated datasets and quality metrics for dynamical models of neural activity.
  bioRxiv
  02/20/2025 Authors: Versteeg C; McCart JD; Ostrow M; Zoltowski DM; Washington CB; Driscoll L; Codol O; Michaels JA; Linderman SW; Sussillo D
• An application-based taxonomy for brain-computer interfaces.
  Nat Biomed Eng
  12/23/2024 Authors: Robinson JT; Norman SL; Angle MR; Constandinou TG; Denison T; Donoghue JP; Field RM; Forsland A; Kouider S; Milln JDR
• Reducing power requirements for high-accuracy decoding in iBCIs.
  J Neural Eng Volume: 21
  11/01/2024 Authors: Karpowicz BM; Bhaduri B; Nason-Tomaszewski SR; Jacques BG; Ali YH; Flint RD; Bechefsky PH; Hochberg LR; AuYong N; Slutzky MW
• Few-shot Algorithms for Consistent Neural Decoding (FALCON) Benchmark.
  bioRxiv
  10/31/2024 Authors: Karpowicz BM; Ye J; Fan C; Tostado-Marcos P; Rizzoglio F; Washington C; Scodeler T; de Lucena D; Nason-Tomaszewski SR; Mender MJ
• A mosaic of whole-body representations in human motor cortex.
  bioRxiv
  09/16/2024 Authors: Deo DR; Okorokova EV; Pritchard AL; Hahn NV; Card NS; Nason-Tomaszewski SR; Jude J; Hosman T; Choi EY; Qiu D
• Diffusion-Based Generation of Neural Activity from Disentangled Latent Codes
  
  07/30/2024 Authors: McCart JD; Sedler AR; Versteeg C; Mifsud D; Rigotti-Thompson M; Pandarinath C
• Diffusion-Based Generation of Neural Activity from Disentangled Latent Codes.
  ArXiv
  07/30/2024 Authors: McCart JD; Sedler AR; Versteeg C; Mifsud D; Rigotti-Thompson M; Pandarinath C
• Spinal interneuron population dynamics underlying flexible pattern generation.
  
  06/23/2024 Authors: Wimalasena LN; Pandarinath C; Yong NA
• Identifying Distinct Neural Features between the Initial and Corrective Phases of Precise Reaching Using AutoLFADS.
  J Neurosci Volume: 44
  05/15/2024 Authors: Lee W-H; Karpowicz BM; Pandarinath C; Rouse AG
• BRAND: a platform for closed-loop experiments with deep network models.
  J Neural Eng Volume: 21
  04/17/2024 Authors: Ali YH; Bodkin K; Rigotti-Thompson M; Patel K; Card NS; Bhaduri B; Nason-Tomaszewski SR; Mifsud DM; Hou X; Nicolas C
• Identifying distinct neural features between the initial and corrective phases of precise reaching using AutoLFADS.
  
  02/04/2024 Authors: Lee W-H; Karpowicz BM; Pandarinath C; Rouse AG
• Myomatrix arrays for high-definition muscle recording.
  Elife Volume: 12
  12/19/2023 Authors: Chung B; Zia M; Thomas KA; Michaels JA; Jacob A; Pack A; Williams MJ; Nagapudi K; Teng LH; Arrambide E
• Pseudo-linear Summation explains Neural Geometry of Multi-finger Movements in Human Premotor Cortex.
  bioRxiv
  10/12/2023 Authors: Shah NP; Avansino D; Kamdar F; Nicolas C; Kapitonava A; Vargas-Irwin C; Hochberg L; Pandarinath C; Shenoy K; Willett FR
• Myomatrix arrays for high-definition muscle recording.
  bioRxiv
  09/19/2023 Authors: Chung B; Zia M; Thomas KA; Michaels JA; Jacob A; Pack A; Williams MJ; Nagapudi K; Teng LH; Arrambide E
• Expressive dynamics models with nonlinear injective readouts enable reliable recovery of latent features from neural activity.
  ArXiv
  09/12/2023 Authors: Versteeg C; Sedler AR; McCart JD; Pandarinath C
• lfads-torch: A modular and extensible implementation of latent factor analysis via dynamical systems
  
  09/03/2023 Authors: Sedler AR; Pandarinath C
• BRAND: A platform for closed-loop experiments with deep network models.
  bioRxiv
  08/12/2023 Authors: Ali YH; Bodkin K; Rigotti-Thompson M; Patel K; Card NS; Bhaduri B; Nason-Tomaszewski SR; Mifsud DM; Hou X; Nicolas C
• Krishna Shenoy (1968-2023).
  Neuron Volume: 111 Page(s): 764 - 766
  03/15/2023 Authors: Batista AP; Pandarinath C; Yu BM
• High-performance neural population dynamics modeling enabled by scalable computational infrastructure.
  J Open Source Softw Volume: 8
  01/01/2023 Authors: Patel AN; Sedler AR; Huang J; Pandarinath C; Gilja V
• Expressive architectures enhance interpretability of dynamics-based neural population models.
  Neuron Behav Data Anal Theory Volume: 2023
  01/01/2023 Authors: Sedler AR; Versteeg C; Pandarinath C
• Expressive architectures enhance interpretability of dynamics-based neural population models
  
  12/07/2022 Authors: Sedler AR; Versteeg C; Pandarinath C
• A deep learning framework for inference of single-trial neural population dynamics from calcium imaging with subframe temporal resolution.
  Nat Neurosci Volume: 25 Page(s): 1724 - 1734
  12/01/2022 Authors: Zhu F; Grier HA; Tandon R; Cai C; Agarwal A; Giovannucci A; Kaufman MT; Pandarinath C
• A large-scale neural network training framework for generalized estimation of single-trial population dynamics.
  Nat Methods Volume: 19 Page(s): 1572 - 1577
  12/01/2022 Authors: Keshtkaran MR; Sedler AR; Chowdhury RH; Tandon R; Basrai D; Nguyen SL; Sohn H; Jazayeri M; Miller LE; Pandarinath C
• Estimating muscle activation from EMG using deep learning-based dynamical systems models.
  J Neural Eng Volume: 19
  05/19/2022 Authors: Wimalasena LN; Braun JF; Keshtkaran MR; Hofmann D; Gallego J; Alessandro C; Tresch MC; Miller LE; Pandarinath C
• The science and engineering behind sensitized brain-controlled bionic hands.
  Physiol Rev Volume: 102 Page(s): 551 - 604
  04/01/2022 Authors: Pandarinath C; Bensmaia SJ
• Neural Latents Benchmark '21: Evaluating latent variable models of neural population activity
  
  09/09/2021 Authors: Pei F; Ye J; Zoltowski D; Wu A; Chowdhury RH; Sohn H; O'Doherty JE; Shenoy KV; Kaufman MT; Churchland M
• Representation learning for neural population activity with Neural Data Transformers
  
  08/02/2021 Authors: Ye J; Pandarinath C
• From unstable input to robust output.
  Nat Biomed Eng Volume: 4 Page(s): 665 - 667
  07/01/2020 Authors: Wimalasena LN; Miller LE; Pandarinath C
• The Representation of Finger Movement and Force in Human Motor and Premotor Cortices.
  eNeuro Volume: 7
  01/01/2020 Authors: Flint RD; Tate MC; Li K; Templer JW; Rosenow JM; Pandarinath C; Slutzky MW
• Principled BCI Decoder Design and Parameter Selection Using a Feedback Control Model.
  Sci Rep Volume: 9 Page(s): 8881
  06/20/2019 Authors: Willett FR; Young DR; Murphy BA; Memberg WD; Blabe CH; Pandarinath C; Stavisky SD; Rezaii P; Saab J; Walter BL
• Volitional control of single-electrode high gamma local field potentials by people with paralysis.
  J Neurophysiol Volume: 121 Page(s): 1428 - 1450
  04/01/2019 Authors: Milekovic T; Bacher D; Sarma AA; Simeral JD; Saab J; Pandarinath C; Yvert B; Sorice BL; Blabe C; Oakley EM
• Brain implants that let you speak your mind.
  Nature Volume: 568 Page(s): 466 - 467
  04/01/2019 Authors: Pandarinath C; Ali YH
• Publisher Correction: Brain-machine interface cursor position only weakly affects monkey and human motor cortical activity in the absence of arm movements.
  Sci Rep Volume: 9 Page(s): 5528
  03/28/2019 Authors: Stavisky SD; Kao JC; Nuyujukian P; Pandarinath C; Blabe C; Ryu SI; Hochberg LR; Henderson JM; Shenoy KV
• Brain-machine interface cursor position only weakly affects monkey and human motor cortical activity in the absence of arm movements.
  Sci Rep Volume: 8 Page(s): 16357
  11/05/2018 Authors: Stavisky SD; Kao JC; Nuyujukian P; Pandarinath C; Blabe C; Ryu SI; Hochberg LR; Henderson JM; Shenoy KV
• Latent Factors and Dynamics in Motor Cortex and Their Application to Brain-Machine Interfaces.
  J Neurosci Volume: 38 Page(s): 9390 - 9401
  10/31/2018 Authors: Pandarinath C; Ames KC; Russo AA; Farshchian A; Miller LE; Dyer EL; Kao JC
• Inferring single-trial neural population dynamics using sequential auto-encoders.
  Nat Methods Volume: 15 Page(s): 805 - 815
  10/01/2018 Authors: Pandarinath C; O'Shea DJ; Collins J; Jozefowicz R; Stavisky SD; Kao JC; Trautmann EM; Kaufman MT; Ryu SI; Hochberg LR
• A Comparison of Intention Estimation Methods for Decoder Calibration in Intracortical Brain-Computer Interfaces.
  IEEE Trans Biomed Eng Volume: 65 Page(s): 2066 - 2078
  09/01/2018 Authors: Willett FR; Murphy BA; Young DR; Memberg WD; Blabe CH; Pandarinath C; Franco B; Saab J; Walter BL; Sweet JA
• Feasibility of Automatic Error Detect-and-Undo System in Human Intracortical Brain-Computer Interfaces.
  IEEE Trans Biomed Eng Volume: 65 Page(s): 1771 - 1784
  08/01/2018 Authors: Even-Chen N; Stavisky SD; Pandarinath C; Nuyujukian P; Blabe CH; Hochberg LR; Henderson JM; Shenoy KV
• Stable long-term BCI-enabled communication in ALS and locked-in syndrome using LFP signals.
  J Neurophysiol Volume: 120 Page(s): 343 - 360
  07/01/2018 Authors: Milekovic T; Sarma AA; Bacher D; Simeral JD; Saab J; Pandarinath C; Sorice BL; Blabe C; Oakley EM; Tringale KR
• Rapid calibration of an intracortical brain-computer interface for people with tetraplegia.
  J Neural Eng Volume: 15 Page(s): 026007
  04/01/2018 Authors: Brandman DM; Hosman T; Saab J; Burkhart MC; Shanahan BE; Ciancibello JG; Sarma AA; Milstein DJ; Vargas-Irwin CE; Franco B
• Cortical control of a tablet computer by people with paralysis.
  PLoS One Volume: 13 Page(s): e0204566
  01/01/2018 Authors: Nuyujukian P; Albites Sanabria J; Saab J; Pandarinath C; Jarosiewicz B; Blabe CH; Franco B; Mernoff ST; Eskandar EN; Simeral JD
• Signal-independent noise in intracortical brain-computer interfaces causes movement time properties inconsistent with Fitts' law.
  J Neural Eng Volume: 14 Page(s): 026010
  04/01/2017 Authors: Willett FR; Murphy BA; Memberg WD; Blabe CH; Pandarinath C; Walter BL; Sweet JA; Miller JP; Henderson JM; Shenoy KV
• High performance communication by people with paralysis using an intracortical brain-computer interface.
  Elife Volume: 6
  02/21/2017 Authors: Pandarinath C; Nuyujukian P; Blabe CH; Sorice BL; Saab J; Willett FR; Hochberg LR; Shenoy KV; Henderson JM
• Feedback control policies employed by people using intracortical brain-computer interfaces.
  J Neural Eng Volume: 14 Page(s): 016001
  02/01/2017 Authors: Willett FR; Pandarinath C; Jarosiewicz B; Murphy BA; Memberg WD; Blabe CH; Saab J; Walter BL; Sweet JA; Miller JP
• LFADS - Latent Factor Analysis via Dynamical Systems
  
  08/22/2016 Authors: Sussillo D; Jozefowicz R; Abbott LF; Pandarinath C
• Virtual typing by people with tetraplegia using a self-calibrating intracortical brain-computer interface.
  Sci Transl Med Volume: 7 Page(s): 313ra179
  11/11/2015 Authors: Jarosiewicz B; Sarma AA; Bacher D; Masse NY; Simeral JD; Sorice B; Oakley EM; Blabe C; Pandarinath C; Gilja V
• Clinical translation of a high-performance neural prosthesis.
  Nat Med Volume: 21 Page(s): 1142 - 1145
  10/01/2015 Authors: Gilja V; Pandarinath C; Blabe CH; Nuyujukian P; Simeral JD; Sarma AA; Sorice BL; Perge JA; Jarosiewicz B; Hochberg LR
• Neural population dynamics in human motor cortex during movements in people with ALS.
  Elife Volume: 4 Page(s): e07436
  06/23/2015 Authors: Pandarinath C; Gilja V; Blabe CH; Nuyujukian P; Sarma AA; Sorice BL; Eskandar EN; Hochberg LR; Henderson JM; Shenoy KV
• Progress toward Robust, High-Performance Intracortically Controlled Point-and-Click Communication for People with Locked-In Syndrome
  Volume: 76 Page(s): S125 - S125
  10/01/2014 Authors: Sarma AA; Jarosiewicz B; Bacher D; Pandarinath C; Nuyujukian P; Sorice BL; Blabe C; Simeral JD; Donoghue JP; Mernoff S
• Recruitment of PfSET2 by RNA polymerase II to variant antigen encoding loci contributes to antigenic variation in P. falciparum.
  PLoS Pathog Volume: 10 Page(s): e1003854
  01/01/2014 Authors: Ukaegbu UE; Kishore SP; Kwiatkowski DL; Pandarinath C; Dahan-Pasternak N; Dzikowski R; Deitsch KW
• A system for optically controlling neural circuits with very high spatial and temporal resolution.
  Volume: 2013
  11/01/2013 Authors: Pandarinath C; Carlson ET; Nirenberg S
• High Performance Computer Cursor Control Using Neuronal Ensemble Recordings From the Motor Cortex of a Person With ALS
  Volume: 60 Page(s): 184 - 184
  08/01/2013 Authors: Henderson JM; Gilja V; Pandarinath C; Blabe C; Hochberg LR; Shenoy KV
• Retinal prosthetic strategy with the capacity to restore normal vision.
  Proc Natl Acad Sci U S A Volume: 109 Page(s): 15012 - 15017
  09/11/2012 Authors: Nirenberg S; Pandarinath C
• Symmetry breakdown in the ON and OFF pathways of the retina at night: functional implications.
  J Neurosci Volume: 30 Page(s): 10006 - 10014
  07/28/2010 Authors: Pandarinath C; Victor JD; Nirenberg S
• How Neural Systems Adjust to Different Environments: An Intriguing Role for Gap Junction Coupling
  Volume: 51
  04/01/2010 Authors: Nirenberg S; Pandarinath C; Bomash I; Victor JD; Prusky GT; Tschetter WW
• A novel mechanism for switching a neural system from one state to another.
  Front Comput Neurosci Volume: 4 Page(s): 2
  01/01/2010 Authors: Pandarinath C; Bomash I; Victor JD; Prusky GT; Tschetter WW; Nirenberg S
• Ganglion cell adaptability: does the coupling of horizontal cells play a role?
  PLoS One Volume: 3 Page(s): e1714
  03/05/2008 Authors: Dedek K; Pandarinath C; Alam NM; Wellershaus K; Schubert T; Willecke K; Prusky GT; Weiler R; Nirenberg S