Carlos Moreno PhD

Department of Pathology and Laboratory Medicine
Professor

Academic Appointment

Professor with Tenure, Pathology and Laboratory Medicine, Emory University

Education

Degrees

PhD from Emory University
M.S. from Massachusetts Institute of Technology
BS from Massachusetts Institute of Technology
No Degree from Harvard University
No Degree from Massachusetts Institute of Technology

Research

Focus

Cancer Bioinformatics, Systems Biology, and Transcriptional Networks. My laboratory is identifying biomarkers and novel targets for cancer therapy. We are also developing novel bioinformatics methods for analysis of high-throughput genetic data. We are focused on two transcription factors, SOX4 and HOXC6, and how these factors may influence the stage of differentiation of cancer cells and their metastatic potential.

Publications

Correction: EZH2 has a non-catalytic and PRC2-independent role in stabilizing DDB2 to promote nucleotide excision repair.
Oncogene Volume: 44 Page(s): 928 - 930
04/01/2025 Authors: Koyen AE; Madden MZ; Park D; Minten EV; Kapoor-Vazirani P; Werner E; Pfister NT; Haji-Seyed-Javadi R; Zhang H; Xu J
Correction: Epidermal growth factor dampens pro-inflammatory gene expression induced by interferon-gamma in global transcriptome analysis of keratinocytes.
BMC Genomics Volume: 26 Page(s): 291
03/24/2025 Authors: Gibbs DC; McCrary MR; Moreno CS; Seldin L; Li C; Kamili NAH; Pollack BP
Epidermal growth factor dampens pro-inflammatory gene expression induced by interferon-gamma in global transcriptome analysis of keratinocytes.
BMC Genomics Volume: 26 Page(s): 122
02/10/2025 Authors: Gibbs DC; McCrary MR; Moreno CS; Seldin L; Li C; Kamili NAH; Pollack BP
Deregulation of ABCG1 early in life contributes to prostate carcinogenesis in maternally malnourished offspring rats.
Mol Cell Endocrinol Volume: 580 Page(s): 112102
01/15/2024 Authors: Camargo AC; Constantino FB; Santos SA; Colombelli KT; Portela LM; Fioretto MN; Barata LA; Valente GT; Moreno CS; Justulin LA
Integrated Genomic Analysis of Primary Prostate Tumor Foci and Corresponding Lymph Node Metastases Identifies Mutations and Pathways Associated with Metastasis.
Cancers (Basel) Volume: 15
11/30/2023 Authors: Moreno CS; Winham CL; Alemozaffar M; Klein ER; Lawal IO; Abiodun-Ojo OA; Patil D; Barwick BG; Huang Y; Schuster DM
Early-life origin of prostate cancer through deregulation of miR-206 networks in maternally malnourished offspring rats.
Sci Rep Volume: 13 Page(s): 18685
10/31/2023 Authors: Portela LMF; Constantino FB; Camargo ACL; Santos SAA; Colombelli KT; Fioretto MN; Barata LA; Silva EJR; Scarano WR; Felisbino SL
New insights into KLFs and SOXs in cancer pathogenesis, stemness, and therapy.
Semin Cancer Biol Volume: 90 Page(s): 29 - 44
05/01/2023 Authors: Zeng L; Zhu Y; Moreno CS; Wan Y
High throughput, label-free isolation of circulating tumor cell clusters in meshed microwells.
Nat Commun Volume: 13 Page(s): 3385
06/13/2022 Authors: Boya M; Ozkaya-Ahmadov T; Swain BE; Chu C-H; Asmare N; Civelekoglu O; Liu R; Lee D; Tobia S; Biliya S
Systematic discovery of mutation-directed neo-protein-protein interactions in cancer.
Cell Volume: 185 Page(s): 1974 - 1985.e12
05/26/2022 Authors: Mo X; Niu Q; Ivanov AA; Tsang YH; Tang C; Shu C; Li Q; Qian K; Wahafu A; Doyle SP
The Movember Global Action Plan 1 (GAP1): Unique Prostate Cancer Tissue Microarray Resource.
Cancer Epidemiol Biomarkers Prev Volume: 31 Page(s): 715 - 727
04/01/2022 Authors: Ouellet V; Erickson A; GAP1 UTMAs Contributing Investigators; Wiley K; Morrissey C; Berge V; Moreno CS; Tasken KA; Trudel D; True LD
Transcriptomic landscape of male and female reproductive cancers: Similar pathways and molecular signatures predicting response to endocrine therapy.
Mol Cell Endocrinol Volume: 535 Page(s): 111393
09/15/2021 Authors: Camargo AC; Remoli B; Portela LM; Fioretto MN; Chuffa LG; Moreno CS; Justulin LA
The need for new test verification and regulatory support for innovative diagnostics.
Nat Biotechnol Volume: 39 Page(s): 1060 - 1062
03/01/2023 Authors: Roback JD; Tyburski EA; Alter D; Asakrah S; Chahroudi A; Esper A; Farmer S; Figueroa J; K Frediani J; D Gonzalez M
Epidermal growth factor modifies immune gene expression in keratinocytes and Melanoma
Volume: 141 Page(s): B8 - B8
03/01/2023 Authors: Gibbs DC; McCrary MR; Moreno CS; Pollack BP
Pan-cancer analysis of pathway-based gene expression pattern at the individual level reveals biomarkers of clinical prognosis.
Cell Rep Methods Volume: 1
08/23/2021 Authors: Su K; Yu Q; Shen R; Sun S-Y; Moreno CS; Li X; Qin ZS
The Hippo effector YAP1 biochemically and functionally interacts with the nuclear factor-kappa B/RELA transcription factor
Volume: 35
05/01/2021 Authors: Cinar B; Said-Bandy E; Mathkour M; Boston A; Dwead A; Moreno C
Variation of microRNA expression in the human placenta driven by population identity and sex of the newborn.
BMC Genomics Volume: 22 Page(s): 286
04/20/2021 Authors: Guo S; Huang S; Jiang X; Hu H; Han D; Moreno CS; Fairbrother GL; Hughes DA; Stoneking M; Khaitovich P
An expanded universe of cancer targets.
Cell Volume: 184 Page(s): 1142 - 1155
03/04/2021 Authors: Hahn WC; Bader JS; Braun TP; Califano A; Clemons PA; Druker BJ; Ewald AJ; Fu H; Jagu S; Kemp CJ
Characterization of exosome release and extracellular vesicle-associated miRNAs for human bronchial epithelial cells irradiated with high charge and energy ions.
Life Sci Space Res (Amst) Volume: 28 Page(s): 11 - 17
02/01/2021 Authors: Li Z; Jella KK; Jaafar L; Moreno CS; Dynan WS
SOX4: The unappreciated oncogene.
Semin Cancer Biol Volume: 67 Page(s): 57 - 64
12/01/2020 Authors: Moreno CS
EPIDERMAL GROWTH FACTOR MODULATION OF CXCL10 IN KERATINOCYTES AND CUTANEOUS CANCERS
Volume: 8 Page(s): A362 - A363
11/01/2020 Authors: McCrary M; Gibbs D; Moreno C; Pollack B
Correction to: Overexpression of SOX4 induces up-regulation of miR-126 and miR-195 in LNCaP prostate cancer cell line.
Cytotechnology Volume: 72 Page(s): 603
08/01/2020 Authors: Phan NN; Moreno CS; Lai Y-H
Overexpression of SOX4 induces up-regulation of miR-126 and miR-195 in LNCaP prostate cancer cell line.
Cytotechnology Volume: 72 Page(s): 527 - 537
08/01/2020 Authors: Phan NN; Moreno CS; Lai Y-H
Androgen attenuates the inactivating phospho-Ser-127 modification of yes-associated protein 1 (YAP1) and promotes YAP1 nuclear abundance and activity.
J Biol Chem Volume: 295 Page(s): 8550 - 8559
06/19/2020 Authors: Cinar B; Al-Mathkour MM; Khan SA; Moreno CS
Hypoxia-associated genes on disparities in the aggressiveness of prostate cancer
Volume: 29
06/01/2020 Authors: Espinoza IC; Moreno CS; Gomez CR
Hypoxia-associated genes on disparities in the aggressiveness of prostate cancer
Volume: 29
06/01/2020 Authors: Espinoza IC; Moreno CS; Gomez CR
EZH2 has a non-catalytic and PRC2-independent role in stabilizing DDB2 to promote nucleotide excision repair.
Oncogene Volume: 39 Page(s): 4798 - 4813
09/01/2015 Authors: Koyen AE; Madden MZ; Park D; Minten EV; Kapoor-Vazirani P; Werner E; Pfister NT; Haji-Seyed-Javadi R; Zhang H; Xu J
Genomic copy number variation correlates with survival outcomes in WHO grade IV glioma.
Sci Rep Volume: 10 Page(s): 7355
04/30/2020 Authors: Buchwald ZS; Tian S; Rossi M; Smith GH; Switchenko J; Hauenstein JE; Moreno CS; Press RH; Prabhu RS; Zhong J
The JNK inhibitor AS602801 Synergizes with Enzalutamide to Kill Prostate Cancer Cells In Vitro and In Vivo and Inhibit Androgen Receptor Expression.
Transl Oncol Volume: 13 Page(s): 100751
04/01/2020 Authors: Li Z; Sun C; Tao S; Osunkoya AO; Arnold RS; Petros JA; Zu X; Moreno CS
Combined HER3-EGFR score in triple-negative breast cancer provides prognostic and predictive significance superior to individual biomarkers.
Sci Rep Volume: 10 Page(s): 3009
02/20/2020 Authors: Ogden A; Bhattarai S; Sahoo B; Mongan NP; Alsaleem M; Green AR; Aleskandarany M; Ellis IO; Pattni S; Li XB
Phosphoinositide 3-Kinase Signaling Can Modulate MHC Class I and II Expression.
Mol Cancer Res Volume: 17 Page(s): 2395 - 2409
12/01/2019 Authors: Chandrasekaran S; Sasaki M; Scharer CD; Kissick HT; Patterson DG; Magliocca KR; Seykora JT; Sapkota B; Gutman DA; Cooper LA
SOX4 regulates invasion of bladder cancer cells via repression of WNT5a.
Int J Oncol Volume: 55 Page(s): 359 - 370
01/01/2019 Authors: Moran JD; Kim HH; Li Z; Moreno CS
Systematic computational analysis of histologic-genomic associations in triple-negative infiltrating ductal carcinomas of the breast
Volume: 79
07/01/2019 Authors: Amgad M; Kurkure U; Elfandy H; Khallaf HH; Gutman DA; Moreno CS; Barnes M; Cooper LA
Combination therapies to prevent resistance to androgen deprivation therapies in prostate cancer
Volume: 79
07/01/2019 Authors: Li Z; Sun CQ; Arnold R; Petros JA; Moreno CS
Use of Everolimus and Trastuzumab in Addition to Endocrine Therapy in Hormone-Refractory Metastatic Breast Cancer.
Clin Breast Cancer Volume: 19 Page(s): 188 - 196
06/01/2019 Authors: Paplomata E; Zelnak A; Santa-Maria CA; Liu Y; Gogineni K; Li X; Moreno CS; Chen Z; Kaklamani V; O'Regan RM
COMBINATION THERAPIES TO PREVENT RESISTANCE TO ANDROGEN DEPRIVATION THERAPY IN PROSTATE CANCER
Volume: 201 Page(s): E320 - E320
04/01/2019 Authors: Li Z; Sun CQ; Arnold R; Petros JA; Moreno CS
Androgen Receptor Signaling Promotes YAP1 Nuclear Localization.
Volume: 29
12/15/2018 Authors: Cinar B; Mathkour M; Khan SA; Moreno CS
Identification of the Transcription Factor Relationships Associated with Androgen Deprivation Therapy Response and Metastatic Progression in Prostate Cancer.
Cancers (Basel) Volume: 10
10/11/2018 Authors: Sharma NV; Pellegrini KL; Ouellet V; Giuste FO; Ramalingam S; Watanabe K; Adam-Granger E; Fossouo L; You S; Freeman MR
Selective modification of fluciclovine (18F) transport in prostate carcinoma xenografts.
Amino Acids Volume: 50 Page(s): 1301 - 1305
09/01/2018 Authors: Tade FI; Wiles WG; Lu G; Bilir B; Akin-Akintayo O; Lee JS; Patil D; Yu W; Ormenisan Gherasim C; Fei B
Transcription factor relationships associated with androgen-deprivation therapy response and metastatic progression in prostate cancer
Volume: 78
07/01/2018 Authors: Sharma NV; Pellegrini KL; Ouellet V; Giuste FO; Ramalingam S; Watanabe K; Adam-Granger E; Fossouo L; You S; Freeman MR
AR signaling in concert with PP2A/B regulates YAP1 expression in prostate cancer cells
Volume: 78
07/01/2018 Authors: Cinar B; Moreno CS
The OncoPPi Portal: an integrative resource to explore and prioritize protein-protein interactions for cancer target discovery.
Bioinformatics Volume: 34 Page(s): 1183 - 1191
04/01/2018 Authors: Ivanov AA; Revennaugh B; Rusnak L; Gonzalez-Pecchi V; Mo X; Johns MA; Du Y; Cooper LAD; Moreno CS; Khuri FR
DETECTION OF PROSTATE CANCER-ASSOCIATED TRANSCRIPTS IN URINARY EXTRACELLULAR VESICLES
Volume: 199 Page(s): E450 - E451
04/01/2018 Authors: Pellegrini K; Patil D; Douglas K; Anastasiades E; Larsen K; Kim F; Catic A; Torlak M; Huang E; Moreno C
The E2F activators control multiple mitotic regulators and maintain genomic integrity through Sgo1 and BubR1.
Oncotarget Volume: 8 Page(s): 77649 - 77672
09/29/2017 Authors: Lee M; Rivera-Rivera Y; Moreno CS; Saavedra HI
Effects of genistein supplementation on genomewide DNA methylation and gene expression in patients with localized prostate cancer.
Int J Oncol Volume: 51 Page(s): 223 - 234
07/01/2017 Authors: Bilir B; Sharma NV; Lee J; Hammarstrom B; Svindland A; Kucuk O; Moreno CS
Enriching gene expression profiles will help personalize prostate cancer management for African-Americans: A perspective.
Urol Oncol Volume: 35 Page(s): 315 - 321
06/01/2017 Authors: Vijayakumar S; Henegan JC; Zhang X; Wang W; Day WA; Vijayakumar V; Moreno CS; Gomez CR
Detection of prostate cancer-specific transcripts in extracellular vesicles isolated from post-DRE urine.
Prostate Volume: 77 Page(s): 990 - 999
06/01/2017 Authors: Pellegrini KL; Patil D; Douglas KJS; Lee G; Wehrmeyer K; Torlak M; Clark J; Cooper CS; Moreno CS; Sanda MG
Evaluation of a 24-gene signature for prognosis of metastatic events and prostate cancer-specific mortality.
BJU Int Volume: 119 Page(s): 961 - 967
06/01/2017 Authors: Pellegrini KL; Sanda MG; Patil D; Long Q; Santiago-Jimnez M; Takhar M; Erho N; Yousefi K; Davicioni E; Klein EA
Corrigendum: The OncoPPi network of cancer-focused protein-protein interactions to inform biological insights and therapeutic strategies.
Nat Commun Volume: 8 Page(s): 15350
04/18/2017 Authors: Li Z; Ivanov AA; Su R; Gonzalez-Pecchi V; Qi Q; Liu S; Webber P; McMillan E; Rusnak L; Pham C
Targeted RNA Sequencing of FFPE Prostate Biopsies and Matched Prostatectomies
Volume: 31
04/01/2017 Authors: Sharma NV; Pellegrini KL; Osunkoya AO; Gillespie T; Petros J; Huang E; Sanda MG; Moreno CS
AKT1, LKB1, and YAP1 Revealed as MYC Interactors with NanoLuc-Based Protein-Fragment Complementation Assay.
Mol Pharmacol Volume: 91 Page(s): 339 - 347
04/01/2017 Authors: Mo X; Qi Q; Ivanov AA; Niu Q; Luo Y; Havel J; Goetze R; Bell S; Moreno CS; Cooper LAD
The OncoPPi network of cancer-focused protein-protein interactions to inform biological insights and therapeutic strategies.
Nat Commun Volume: 8 Page(s): 14356
02/16/2017 Authors: Li Z; Ivanov AA; Su R; Gonzalez-Pecchi V; Qi Q; Liu S; Webber P; McMillan E; Rusnak L; Pham C
RNA Sequencing of Patient Matched Pre-Androgen Deprivation Therapy and Post-Androgen Deprivation Therapy Prostate Cancer Identifies Mechanisms of Progression to Castration-Resistant Prostate Cancer
Volume: 30 Page(s): 245A - 245A
02/01/2017 Authors: Moreno CS; Giuste FO; Pellegrini KL; Sharma NV; Ouellet V; Trudel D; Mes-Masson A-M; Petros JA; Saad F; Osunkoya AO
SOX4 Expression in Prostatic Adenocarcinoma with Matched Lymph Node Metastasis
Volume: 30 Page(s): 247A - 247A
02/01/2017 Authors: Gherasim CO; Annan AC; Bilir B; Moreno CS; Osunkoya AO
Does Injection of 2-Aminobicyclo-(2,2,1)-Heptane-2-Carboxylic Acid (BCH) Affect Amino Acid Transporter Density in Prostate Cancer Xenografts?
Volume: 30 Page(s): 247A - 247A
02/01/2017 Authors: Ormenisan-Gherasim C; Tade F; Akin-Akintayo OO; Bilir B; Wiles WG; Lu G; Fei B; Moreno CS; Goodman MM; Schuster DM
SOX4 Expression in Prostatic Adenocarcinoma with Matched Lymph Node Metastasis
Volume: 97 Page(s): 247A - 247A
02/01/2017 Authors: Gherasim CO; Annan AC; Bilir B; Moreno CS; Osunkoya AO
Does Injection of 2-Aminobicyclo-(2,2,1)-Heptane-2-Carboxylic Acid (BCH) Affect Amino Acid Transporter Density in Prostate Cancer Xenografts?
Volume: 97 Page(s): 247A - 247A
02/01/2017 Authors: Ormenisan-Gherasim C; Tade F; Akin-Akintayo OO; Bilir B; Wiles WG; Lu G; Fei B; Moreno CS; Goodman MM; Schuster DM
RNA Sequencing of Patient Matched Pre-Androgen Deprivation Therapy and Post-Androgen Deprivation Therapy Prostate Cancer Identifies Mechanisms of Progression to Castration-Resistant Prostate Cancer
Volume: 97 Page(s): 245A - 245A
02/01/2017 Authors: Moreno CS; Giuste FO; Pellegrini KL; Sharma NV; Ouellet V; Trudel D; Mes-Masson A-M; Petros JA; Saad F; Osunkoya AO
MEDICI: Mining Essentiality Data to Identify Critical Interactions for Cancer Drug Target Discovery and Development.
PLoS One Volume: 12 Page(s): e0170339
01/01/2017 Authors: Harati S; Cooper LAD; Moran JD; Giuste FO; Du Y; Ivanov AA; Johns MA; Khuri FR; Fu H; Moreno CS
Cosmc is an X-linked inflammatory bowel disease risk gene that spatially regulates gut microbiota and contributes to sex-specific risk.
Proc Natl Acad Sci U S A Volume: 113 Page(s): 14787 - 14792
12/20/2016 Authors: Kudelka MR; Hinrichs BH; Darby T; Moreno CS; Nishio H; Cutler CE; Wang J; Wu H; Zeng J; Wang Y
MELK kinase holds promise as a new radiosensitizing target and biomarker in triple-negative breast cancer.
J Thorac Dis Volume: 8 Page(s): E1367 - E1368
10/01/2016 Authors: Moreno CS
Transforming Big Data into Cancer-Relevant Insight: An Initial, Multi-Tier Approach to Assess Reproducibility and Relevance.
Mol Cancer Res Volume: 14 Page(s): 675 - 682
08/01/2016 Authors: Cancer Target Discovery and Development Network
SOX4 is essential for PTEN-mediated prostate tumorigenesis in vivo
Volume: 76
07/01/2016 Authors: Bilir B; Osunkoya AO; Wiles WG; Sannigrahi S; Lefebvre V; Metzger D; Spyropoulos DD; Martin WD; Moreno CS
Gene integrated set profile analysis: a context-based approach for inferring biological endpoints.
Nucleic Acids Res Volume: 44 Page(s): e69
04/20/2016 Authors: Kowalski J; Dwivedi B; Newman S; Switchenko JM; Pauly R; Gutman DA; Arora J; Gandhi K; Ainslie K; Doho G
IDENTIFICATION OF RACE-SPECIFIC BIOMARKERS FOR PROSTATE CANCER PROGRESSION FROM FORMALIN-FIXED BIOPSY TISSUE.
Volume: 195 Page(s): E10 - E11
04/01/2016 Authors: Petros J; Arnold R; Xu J; Long Q; Sannigrahi S; Park J; Osunkoya A; Moreno C
TARGETED SEQUENCING OF PROSTATE CANCER-ASSOCIATED RNAS IN EXTRACELLULAR VESICLES FROM POST-DRE URINE
Volume: 195 Page(s): E12 - E13
04/01/2016 Authors: Pellegrini K; Patil D; Douglas K; Wehrmeyer K; Bausum A; Torlak M; Sanda M; Moreno C
SOX4 Is Essential for Prostate Tumorigenesis Initiated by PTEN Ablation.
Cancer Res Volume: 76 Page(s): 1112 - 1121
03/01/2016 Authors: Bilir B; Osunkoya AO; Wiles WG; Sannigrahi S; Lefebvre V; Metzger D; Spyropoulos DD; Martin WD; Moreno CS
Role of SOX4 in PTEN-Mediated Prostate Tumorigenesis
Volume: 29 Page(s): 457A - 457A
02/01/2016 Authors: Moreno C; Bilir B; Wiles W; Sannigrahi S; Lefebvre V; Chambon P; Spyropoulos D; Martin D; Osunkoya AO
Role of SOX4 in PTEN-Mediated Prostate Tumorigenesis
Volume: 96 Page(s): 457A - 457A
02/01/2016 Authors: Moreno C; Bilir B; Wiles W; Sannigrahi S; Lefebvre V; Chambon P; Spyropoulos D; Martin D; Osunkoya AO
The role of SOX4 in epithelial to mesenchymal transition in prostate cancer
Volume: 76
01/15/2016 Authors: Sharma NV; Sannigrahi S; Lai Y; Moreno C
Abstract A46: Effects of genistein supplementation on genome-wide DNA methylation and gene expression in patients with localized prostate cancer
Volume: 76
01/15/2016 Authors: Bilir B; Lee JE; Sharma NV; Lazarevic B; Svindland A; Kucuk O; Moreno CS
Hierarchical Feature Selection Incorporating Known and Novel Biological Information: Identifying Genomic Features Related to Prostate Cancer Recurrence.
J Am Stat Assoc Volume: 111 Page(s): 1427 - 1439
01/01/2016 Authors: Zhao Y; Chung M; Johnson BA; Moreno CS; Long Q
Claudin-based barrier differentiation in the colonic epithelial crypt niche involves Hopx/Klf4 and Tcf7l2/Hnf4- cascades.
Tissue Barriers Volume: 4 Page(s): e1214038
01/01/2016 Authors: Lili LN; Farkas AE; Gerner-Smidt C; Overgaard CE; Moreno CS; Parkos CA; Capaldo CT; Nusrat A
Predicting the essentialities of protein-protein interactions in cancer
CANCER RESEARCH Volume: 75
11/15/2015 Authors: Cooper LAD; Moran JD; Li Z; Du Y; Harati S; Ivanov AA; Webber P; Havel JJ; Johns MA; Fu H
RNA biomarkers to facilitate the identification of aggressive prostate cancer.
Mol Aspects Med Volume: 45 Page(s): 37 - 46
11/01/2015 Authors: Pellegrini KL; Sanda MG; Moreno CS
Lycopene in the prevention of renal cell cancer in the TSC2 mutant Eker rat model.
Volume: 572 Page(s): 36 - 39
04/15/2015 Authors: Sahin K; Cross B; Sahin N; Ciccone K; Suleiman S; Osunkoya AO; Master V; Harris W; Carthon B; Mohammad R
Evaluating intra- and inter-individual variation in the human placental transcriptome.
Genome Biol Volume: 16 Page(s): 54
03/19/2015 Authors: Hughes DA; Kircher M; He Z; Guo S; Fairbrother GL; Moreno CS; Khaitovich P; Stoneking M
Comparative Genetic Analysis of Invasion-Resistant (Complex Non-Mucinous Pyloric) and Invasion-Prone Types of Intracholecytstic Papillary-Tubular Neoplasms of the Gallbladder
Volume: 95 Page(s): 187A - 187A
02/01/2015 Authors: Robinson B; Fisher K; Xu J; Balci S; Rossi M; Moreno C; Quigley B; Reid M; Roa J; Basturk O
Genomic RNAseq From Formalin Fixed Paraffin Embedded (FFPE) Prostate Needle Core Biopsies of Patients With Prostatic Adenocarcinoma
Volume: 28 Page(s): 246A - 246A
02/01/2015 Authors: Moreno C; Long Q; Sannigrahi S; Gillespie T; Petros J; Sanda M; Osunkoya A
Genomic RNAseq From Formalin Fixed Paraffin Embedded (FFPE) Prostate Needle Core Biopsies of Patients With Prostatic Adenocarcinoma
Volume: 95 Page(s): 246A - 246A
02/01/2015 Authors: Moreno C; Long Q; Sannigrahi S; Gillespie T; Petros J; Sanda M; Osunkoya A
The biology of castration-resistant prostate cancer.
Curr Probl Cancer Volume: 39 Page(s): 17 - 28
01/01/2015 Authors: Lian F; Sharma NV; Moran JD; Moreno CS
Global transcriptome sequencing of ethnically diverse formalin-fixed patient samples identifies biomarkers of recurrence in prostate cancer
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION Volume: 23
11/01/2014 Authors: Xu J; Long Q; Osunkoya AO; Sannigrahi S; Johnson BA; Zhou W; Gillespie T; Park JY; Nam RK; Sugar L
TRIM3, the human homolog of Drosophila Brat, is a tumor suppressor that regulates asymmetric cell division (ACD) in glioblastoma stem cells
Volume: 74
10/01/2014 Authors: Mukherjee S; Chen G; Anand M; Kong J; Tucker-Burden C; Rong Y; Rahman F; Moreno C; Van Meir E; Hadjipanayis C
Human Brat ortholog TRIM3 is a tumor suppressor that regulates asymmetric cell division in glioblastoma.
Cancer Res Volume: 74 Page(s): 4536 - 4548
08/15/2014 Authors: Chen G; Kong J; Tucker-Burden C; Anand M; Rong Y; Rahman F; Moreno CS; Van Meir EG; Hadjipanayis CG; Brat DJ
E2F activators signal and maintain centrosome amplification in breast cancer cells.
Mol Cell Biol Volume: 34 Page(s): 2581 - 2599
07/01/2014 Authors: Lee M-Y; Moreno CS; Saavedra HI
Global transcriptome analysis of formalin-fixed prostate cancer specimens identifies biomarkers of disease recurrence.
Cancer Res Volume: 74 Page(s): 3228 - 3237
06/15/2014 Authors: Long Q; Xu J; Osunkoya AO; Sannigrahi S; Johnson BA; Zhou W; Gillespie T; Park JY; Nam RK; Sugar L
Assessing needs and assets for building a regional network infrastructure to reduce cancer related health disparities.
Eval Program Plann Volume: 44 Page(s): 14 - 25
06/01/2014 Authors: Wells KJ; Lima DS; Meade CD; Muoz-Antonia T; Scarinci I; McGuire A; Gwede CK; Pledger WJ; Partridge E; Lipscomb J
Gene expression profiling of clear cell papillary renal cell carcinoma: comparison with clear cell renal cell carcinoma and papillary renal cell carcinoma.
Mod Pathol Volume: 27 Page(s): 222 - 230
02/01/2014 Authors: Fisher KE; Yin-Goen Q; Alexis D; Sirintrapun JS; Harrison W; Benjamin Isett R; Rossi MR; Moreno CS; Young AN; Osunkoya AO
Biomarkers Differentially Expressed in Prostatic Adenocarcinoma Gleason Score 3+4=7 vs Gleason Score 4+3=7 Identified by Global Transcriptome Sequencing of Forman-Fixed Paraffin Embedded Tissue
Volume: 94 Page(s): 250A - 250A
02/01/2014 Authors: Moreno CS; Long Q; Xu J; Sannigrahi S; Johnson BA; Zhou W; Gillespie T; Park JY; Nam RK; Sugar L
Biomarkers Differentially Expressed in Prostatic Adenocarcinoma Gleason Score 3+4=7 vs Gleason Score 4+3=7 Identified by Global Transcriptome Sequencing of Formalin-Fixed Paraffin Embedded Tissue
Volume: 27 Page(s): 250A - 250A
02/01/2014 Authors: Moreno CS; Long Q; Xu J; Sannigrahi S; Johnson BA; Zhou W; Gillespie T; Park JY; Nam RK; Sugar L
Global Transcriptome Sequencing of Formalin Fixed Paraffin Embedded Patient Samples Identifies Biomarkers That Are Differentially Expressed between Caucasian and African American Men with Prostate Cancer
Volume: 27 Page(s): 250A - 250A
02/01/2014 Authors: Moreno CS; Xu J; Long Q; Sannigrahi S; Johnson BA; Zhou W; Gillespie T; Park JY; Nam RK; Sugar L
Global Transcriptome Sequencing of Formalin Fixed Paraffin Embedded Patient Samples Identifies Biomarkers That Are Differentially Expressed between Caucasian and African American Men with Prostate Cancer
Volume: 94 Page(s): 250A - 250A
02/01/2014 Authors: Moreno CS; Xu J; Long Q; Sannigrahi S; Johnson BA; Zhou W; Gillespie T; Park JY; Nam RK; Sugar L
Integrated analysis of whole-genome paired-end and mate-pair sequencing data for identifying genomic structural variations in multiple myeloma.
Cancer Inform Volume: 13 Page(s): 49 - 53
01/01/2014 Authors: Yang R; Chen L; Newman S; Gandhi K; Doho G; Moreno CS; Vertino PM; Bernal-Mizarchi L; Lonial S; Boise LH
Mutation of murine Sox4 untranslated regions results in partially penetrant perinatal lethality.
In Vivo Volume: 28 Page(s): 709 - 718
01/01/2014 Authors: Wiles WG; Mou Z; Du Y; Long AB; Scharer CD; Bilir B; Spyropoulos DD; Jenkins NA; Copeland NG; Martin WD
High-Performance Computational Analysis of Glioblastoma Pathology Images with Database Support Identifies Molecular and Survival Correlates.
Proceedings (IEEE Int Conf Bioinformatics Biomed) Page(s): 229 - 236
12/01/2013 Authors: Kong J; Wang F; Teodoro G; Cooper L; Moreno CS; Kurc T; Pan T; Saltz J; Brat D
Wnt signaling in triple negative breast cancer is associated with metastasis.
BMC Cancer Volume: 13 Page(s): 537
11/10/2013 Authors: Dey N; Barwick BG; Moreno CS; Ordanic-Kodani M; Chen Z; Oprea-Ilies G; Tang W; Catzavelos C; Kerstann KF; Sledge GW
Wnt signaling blockage inhibits cell proliferation and migration, and induces apoptosis in triple-negative breast cancer cells.
J Transl Med Volume: 11 Page(s): 280
11/04/2013 Authors: Bilir B; Kucuk O; Moreno CS
A NOVEL PARADIGM FOR DETERMINING MOLECULAR CORRELATES OF TUMOR CELL MORPHOLOGY IN HUMAN GLIOMA WHOLE SLIDE IMAGES
NEURO-ONCOLOGY Volume: 15 Page(s): 158 - 159
11/01/2013 Authors: Kong J; Cooper L; Wang F; Gao J; Teodoro G; Scarpace L; Mikkelsen T; Schniederjan M; Moreno C; Saltz J
Tumor-infiltrating lymphocytes in glioblastoma are associated with specific genomic alterations and related to transcriptional class.
Clin Cancer Res Volume: 19 Page(s): 4951 - 4960
09/15/2013 Authors: Rutledge WC; Kong J; Gao J; Gutman DA; Cooper LAD; Appin C; Park Y; Scarpace L; Mikkelsen T; Cohen ML
Methylation signatures specific to triple negative breast cancer subtypes
CANCER RESEARCH Volume: 73
07/01/2013 Authors: Kowalski J; Switchenko JM; Dwivedi B; Nickleach D; Moreno CS
MR imaging predictors of molecular profile and survival: multi-institutional study of the TCGA glioblastoma data set.
Radiology Volume: 267 Page(s): 560 - 569
05/01/2013 Authors: Gutman DA; Cooper LAD; Hwang SN; Holder CA; Gao J; Aurora TD; Dunn WD; Scarpace L; Mikkelsen T; Jain R
RNAseq Analysis of FFPE Radical Prostatectomy Specimens Identifies Predictors of Biochemical Recurrence
Volume: 27
04/01/2013 Authors: Moreno CS; Long Q; Sannigrahi S; Xu J; Johnson BA; Zhou W; Nam RK; Seth A; Gillespie TW; Osunkoya AO
Computational identification of conserved transcription factor binding sites upstream of genes induced in rat brain by transient focal ischemic stroke.
Brain Res Volume: 1495 Page(s): 76 - 85
02/07/2013 Authors: Pulliam JVK; Xu Z; Ford GD; Liu C; Li Y; Stovall KC; Cannon VS; Tewolde T; Moreno CS; Ford BD
RNAseq Analysis of Formalin Fixed Paraffin Embedded Radical Prostatectomy Specimens Identifies Predictors of Biochemical Recurrence in Prostate Cancer
Volume: 93 Page(s): 235A - 235A
02/01/2013 Authors: Moreno CS; Long Q; Sannigrahi S; Xu J; Johnson BA; Zhou W; Seth AK; Nam RK; Petros JA; Gillespie TW
Tumor-Infiltrating Lymphocytes in Glioblastoma Are Associated with Mutations in NF1, RB1 and TP53 and Enriched in the Mesenchymal Transcriptional Class
LABORATORY INVESTIGATION Volume: 93 Page(s): 414A - 415A
02/01/2013 Authors: Brat D; Rutledge C; Kong J; Gutman D; Cooper L; Appin C; Chisolm C; Park Y; Scarpace L; Mikkelsen T
Tumor-Infiltrating Lymphocytes in Glioblastoma Are Associated with Mutations in NF1, RB1 and TP53 and Enriched in the Mesenchymal Transcriptional Class
MODERN PATHOLOGY Volume: 26 Page(s): 414A - 415A
02/01/2013 Authors: Brat D; Rutledge C; Kong J; Gutman D; Cooper L; Appin C; Chisolm C; Park Y; Scarpace L; Mikkelsen T
RNAseq Analysis of Formalin Fixed Paraffin Embedded Radical Prostatectomy Specimens Identifies Predictors of Biochemical Recurrence in Prostate Cancer
Volume: 26 Page(s): 235A - 235A
02/01/2013 Authors: Moreno CS; Long Q; Sannigrahi S; Xu J; Johnson BA; Zhou W; Seth AK; Nam RK; Petros JA; Gillespie TW
Machine-based morphologic analysis of glioblastoma using whole-slide pathology images uncovers clinically relevant molecular correlates.
PLoS One Volume: 8 Page(s): e81049
01/01/2013 Authors: Kong J; Cooper LAD; Wang F; Gao J; Teodoro G; Scarpace L; Mikkelsen T; Schniederjan MJ; Moreno CS; Saltz JH
Characterization of primary prostate carcinoma by anti-1-amino-2-[(18)F] -fluorocyclobutane-1-carboxylic acid (anti-3-[(18)F] FACBC) uptake.
Am J Nucl Med Mol Imaging Volume: 3 Page(s): 85 - 96
01/01/2013 Authors: Schuster DM; Taleghani PA; Nieh PT; Master VA; Amzat R; Savir-Baruch B; Halkar RK; Fox T; Osunkoya AO; Moreno CS
Gene Expression Profiling of Clear Cell Papillary Renal Cell Carcinoma
Volume: 14 Page(s): 697 - 698
11/01/2012 Authors: Fisher KE; Yin-Goen Q; Alexis D; Sirintrapun JS; Harrison W; Isett RB; Rossi MR; Moreno CS; Young AN; Osunkoya AO
TUMOR-INFILTRATING LYMPHOCYTES IN GLIOBLASTOMA ARE ASSOCIATED WITH NF1, TP53, AND RB1 MUTATIONS AND THE MESENCHYMAL TRANSCRIPTIONAL SUBTYPE
Volume: 14 Page(s): 41 - 41
10/01/2012 Authors: Rutledge WC; Kong J; Gao J; Gutman DA; Cooper LA; Chisolm C; Scarpace L; Mikkelsen T; Saltz JH; Moreno CS
The tumor microenvironment strongly impacts master transcriptional regulators and gene expression class of glioblastoma.
Am J Pathol Volume: 180 Page(s): 2108 - 2119
05/01/2012 Authors: Cooper LAD; Gutman DA; Chisolm C; Appin C; Kong J; Rong Y; Kurc T; Van Meir EG; Saltz JH; Moreno CS
Quantitative imaging of protein expression using multiplex quantum dot immunohistochemistry
CANCER RESEARCH Volume: 72
04/15/2012 Authors: Cooper LAD; Yacoub R; Gutman DA; Wang F; Moreno CS; Brat DJ; Bostick RM; Saltz JH
Genistein cooperates with the histone deacetylase inhibitor vorinostat to induce cell death in prostate cancer cells.
BMC Cancer Volume: 12 Page(s): 145
04/11/2012 Authors: Phillip CJ; Giardina CK; Bilir B; Cutler DJ; Lai Y-H; Kucuk O; Moreno CS
Gene Expression Profiling of Clear Cell Papillary Renal Cell Carcinoma
Volume: 92 Page(s): 204A - 205A
02/01/2012 Authors: Fisher KE; Yin-Goen Q; Alexis D; Sirintrapun JS; Harrison W; Isett BR; Rossi MR; Moreno CS; Young AN; Osunkoya AO
Gene Expression Profiling of Clear Cell Papillary Renal Cell Carcinoma
Volume: 25 Page(s): 204A - 205A
02/01/2012 Authors: Fisher KE; Yin-Goen Q; Alexis D; Sirintrapun JS; Harrison W; Isett BR; Rossi MR; Moreno CS; Young AN; Osunkoya AO
Correlation of Immunohistochemical Expression of Protein-Coding Genes RAD23B, SIM2S, Notch3, BID and FBP with Biochemical Recurrence in Patients Following Radical Prostatectomy for Prostatic Adenocarcinoma
Volume: 92 Page(s): 230A - 230A
02/01/2012 Authors: Moreno CS; Sannigrahi S; Cheng J; Zhou W; Petros JA; Gillespie TW; Osunkoya AO
Correlation of Immunohistochemical Expression of Protein-Coding Genes RAD23B, SIM2S, Notch3, BID and FBP with Biochemical Recurrence in Patients Following Radical Prostatectomy for Prostatic Adenocarcinoma
Volume: 25 Page(s): 230A - 230A
02/01/2012 Authors: Moreno CS; Sannigrahi S; Cheng J; Zhou W; Petros JA; Gillespie TW; Osunkoya AO
Integrated morphologic analysis for the identification and characterization of disease subtypes.
J Am Med Inform Assoc Volume: 19 Page(s): 317 - 323
01/01/2012 Authors: Cooper LAD; Kong J; Gutman DA; Wang F; Gao J; Appin C; Cholleti S; Pan T; Sharma A; Scarpace L
Integrative, multimodal analysis of glioblastoma using TCGA molecular data, pathology images, and clinical outcomes.
IEEE Trans Biomed Eng Volume: 58 Page(s): 3469 - 3474
12/01/2011 Authors: Kong J; Cooper LAD; Wang F; Gutman DA; Gao J; Chisolm C; Sharma A; Pan T; Van Meir EG; Kurc TM
SOX4 interacts with plakoglobin in a Wnt3a-dependent manner in prostate cancer cells.
BMC Cell Biol Volume: 12 Page(s): 50
11/19/2011 Authors: Lai Y-H; Cheng J; Cheng D; Feasel ME; Beste KD; Peng J; Nusrat A; Moreno CS
ETV1 Is a Survival Gene That Is Expressed in a Subset of Multiple Myeloma
Volume: 118 Page(s): 1244 - 1245
11/18/2011 Authors: Kim S-J; Moreno CS; Lonial S; Boise LH
Molecular characterisation of formalin-fixed paraffin-embedded (FFPE) breast tumour specimens using a custom 512-gene breast cancer bead array-based platform.
Br J Cancer Volume: 105 Page(s): 1574 - 1581
11/08/2011 Authors: Abramovitz M; Barwick BG; Willis S; Young B; Catzavelos C; Li Z; Kodani M; Tang W; Bouzyk M; Moreno CS
Heterogeneity of primary glioblastoma cells in the expression of caspase-8 and the response to TRAIL-induced apoptosis.
Apoptosis Volume: 16 Page(s): 1150 - 1164
11/01/2011 Authors: Qi L; Bellail AC; Rossi MR; Zhang Z; Pang H; Hunter S; Cohen C; Moreno CS; Olson JJ; Li S
Relative burden of large CNVs on a range of neurodevelopmental phenotypes.
PLoS Genet Volume: 7 Page(s): e1002334
11/01/2011 Authors: Girirajan S; Brkanac Z; Coe BP; Baker C; Vives L; Vu TH; Shafer N; Bernier R; Ferrero GB; Silengo M
C/EBP-B AND C/EBP-DELTA, MASTER REGULATORS OF THE MESENCHYMAL TRANSITION IN GLIOBLASTOMA, ARE HIGHLY CORRELATED WITH EXTENT OF NECROSIS AND STRONGLY EXPRESSED BY HYPOXIC PSEUDOPALISADING CELLS
NEURO-ONCOLOGY Volume: 13 Page(s): 80 - 81
11/01/2011 Authors: Brat DJ; Cooper LA; Gutman DA; Chisolm CS; Appin C; Kong J; Kurc T; Van Meir EG; Saltz JH; Moreno CS
Protein phosphatase 2a (PP2A) binds within the oligomerization domain of striatin and regulates the phosphorylation and activation of the mammalian Ste20-Like kinase Mst3.
BMC Biochem Volume: 12 Page(s): 54
10/10/2011 Authors: Gordon J; Hwang J; Carrier KJ; Jones CA; Kern QL; Moreno CS; Karas RH; Pallas DC
Risk Prediction for Prostate Cancer Recurrence Through Regularized Estimation with Simultaneous Adjustment for Nonlinear Clinical Effects.
Ann Appl Stat Volume: 5 Page(s): 2003 - 2023
09/01/2011 Authors: Long Q; Chung M; Moreno CS; Johnson BA
Protein-coding and microRNA biomarkers of recurrence of prostate cancer following radical prostatectomy.
Am J Pathol Volume: 179 Page(s): 46 - 54
07/01/2011 Authors: Long Q; Johnson BA; Osunkoya AO; Lai Y-H; Zhou W; Abramovitz M; Xia M; Bouzyk MB; Nam RK; Sugar L
Integrated Analysis of Necrosis, Angiogenesis, and Gene Expression in Glioblastoma
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY Volume: 70 Page(s): 498 - 498
06/01/2011 Authors: Brat D; Cooper L; Moreno C; Chisolm C; Appin C; Gutman D; Kong J; Kurc T; Saltz J
Protein-coding and MicroRNA Biomarkers of Recurrence of Prostate Cancer Following Radical Prostatectomy
FASEB JOURNAL Volume: 25
04/01/2011 Authors: Moreno CS; Long Q; Johnson BA; Osunkoya AO; Zhou W; Abramovitz M; Xia M; Bouzyk MB; Nam RK; Sugar L
MORPHOLOGICAL SIGNATURES AND GENOMIC CORRELATES IN GLIOBLASTOMA.
Proc IEEE Int Symp Biomed Imaging Page(s): 1624 - 1627
03/30/2011 Authors: Cooper LAD; Kong J; Wang F; Kurc T; Moreno CS; Brat DJ; Saltz JH
A COMPREHENSIVE FRAMEWORK FOR CLASSIFICATION OF NUCLEI IN DIGITAL MICROSCOPY IMAGING: AN APPLICATION TO DIFFUSE GLIOMAS.
Proc IEEE Int Symp Biomed Imaging Page(s): 2128 - 2131
03/30/2011 Authors: Kong J; Cooper L; Wang F; Chisolm C; Moreno C; Kurc T; Widener P; Brat D; Saltz J
miR-221 Is down-regulated in TMPRSS2:ERG fusion-positive prostate cancer.
Anticancer Res Volume: 31 Page(s): 403 - 410
02/01/2011 Authors: Gordanpour A; Stanimirovic A; Nam RK; Moreno CS; Sherman C; Sugar L; Seth A
High Levels of Necrosis in TCGA Glioblastoma Samples Are Associated with the Mesenchymal Gene Expression Class and Characterized by Enhanced Expression of Master Transcriptional Regulators of Mesenchymal Transition
MODERN PATHOLOGY Volume: 24 Page(s): 440A - 440A
02/01/2011 Authors: Brat DJ; Gutman DA; Cooper LAD; Kong J; Chisolm C; Van Meir EG; Saltz JH; Moreno CS
Computer-Based Classification of Nuclei in Gliomas
MODERN PATHOLOGY Volume: 24 Page(s): 340A - 340A
02/01/2011 Authors: Kong J; Cooper LAD; Chisolm CS; Wang F; Moreno CS; Kurc T; Brat DJ; Saltz JH
High Levels of Necrosis in TCGA Glioblastoma Samples Are Associated with the Mesenchymal Gene Expression Class and Characterized by Enhanced Expression of Master Transcriptional Regulators of Mesenchymal Transition.
LABORATORY INVESTIGATION Volume: 91 Page(s): 440A - 440A
02/01/2011 Authors: Brat DJ; Gutman DA; Cooper LAD; Kong J; Chisolm C; Van Meir EG; Saltz JH; Moreno CS
Computer-Based Classification of Nuclei in Gliomas
LABORATORY INVESTIGATION Volume: 91 Page(s): 340A - 340A
02/01/2011 Authors: Kong J; Cooper LAD; Chisolm CS; Wang F; Moreno CS; Kure T; Brat DJ; Saltz JH
Identification of candidate genes for histiocytoid cardiomyopathy (HC) using whole genome expression analysis: analyzing material from the HC registry.
Pediatr Dev Pathol Volume: 14 Page(s): 370 - 377
01/01/2011 Authors: Shehata BM; Bouzyk M; Shulman SC; Tang W; Steelman CK; Davis GK; Moreno CS
In silico analysis of nuclei in glioblastoma using large-scale microscopy images improves prediction of treatment response.
Annu Int Conf IEEE Eng Med Biol Soc Volume: 2011 Page(s): 87 - 90
01/01/2011 Authors: Kong J; Cooper L; Moreno C; Wang F; Kurc T; Saltz J; Brat D
IN SILICO ANALYSIS OF THE INFLUENCE OF NECROSIS ON GENE EXPRESSION NETWORKS IN GLIOBLASTOMA USING THE CANCER GENOME ATLAS DATA
Volume: 12 Page(s): 67 - 67
11/01/2010 Authors: Gutman DA; Cooper L; Kong J; Chisolm C; Van Meir EG; Saltz JH; Moreno CS; Brat DJ
An integrative approach for in silico glioma research.
IEEE Trans Biomed Eng Volume: 57 Page(s): 2617 - 2621
10/01/2010 Authors: Cooper LAD; Kong J; Gutman DA; Wang F; Cholleti SR; Pan TC; Widener PM; Sharma A; Mikkelsen T; Flanders AE
The proneural molecular signature is enriched in oligodendrogliomas and predicts improved survival among diffuse gliomas.
PLoS One Volume: 5 Page(s): e12548
09/03/2010 Authors: Cooper LAD; Gutman DA; Long Q; Johnson BA; Cholleti SR; Kurc T; Saltz JH; Brat DJ; Moreno CS
Comprehensive Characterization of SOX4 Protein Complexes in Prostate Cancer Cells
Volume: 70
04/01/2010 Authors: Lai Y-H; Peng J; Cheng J; Moreno CS
The TOGA proneural subtype predicts improved clinical outcome for low-grade oligodendrogliomas
Volume: 70
04/01/2010 Authors: Moreno CS; Cooper L; Cholleti SR; Gutman D; Kurk T; Brat DJ; Saltz JH
Consolidation of the cancer genome into domains of repressive chromatin by long-range epigenetic silencing (LRES) reduces transcriptional plasticity.
Nat Cell Biol Volume: 12 Page(s): 235 - 246
03/01/2010 Authors: Coolen MW; Stirzaker C; Song JZ; Statham AL; Kassir Z; Moreno CS; Young AN; Varma V; Speed TP; Cowley M
Prostate cancer genes associated with TMPRSS2-ERG gene fusion and prognostic of biochemical recurrence in multiple cohorts.
Br J Cancer Volume: 102 Page(s): 570 - 576
02/02/2010 Authors: Barwick BG; Abramovitz M; Kodani M; Moreno CS; Nam R; Tang W; Bouzyk M; Seth A; Leyland-Jones B
The Sex-determining region Y-box 4 and homeobox C6 transcriptional networks in prostate cancer progression: crosstalk with the Wnt, Notch, and PI3K pathways.
Am J Pathol Volume: 176 Page(s): 518 - 527
02/01/2010 Authors: Moreno CS
Identification of Candidate Genes for Histiocytoid Cardiomyopathy Using Whole Genome Analysis: Analyzing Material from the HC Registry
Volume: 23 Page(s): 299 - 299
02/01/2010 Authors: Shehata BM; Bouzyk M; Tang W; Steelman CK; Moreno CS
EPLIN Expression in Primary and Metastatic Prostatic Adenocarcinoma: A Tissue Microarray Analysis of 102 Patients
Volume: 90 Page(s): 228A - 229A
02/01/2010 Authors: Wu D; Zhang S; Moreno CS; Osunkoya AO
EPLIN Expression in Primary and Metastatic Prostatic Adenocarcinoma: A Tissue Microarray Analysis of 102 Patients
Volume: 23 Page(s): 228A - 229A
02/01/2010 Authors: Wu D; Zhang S; Moreno CS; Osunkaya AO
KCN1, A NOVEL SMALL MOLECULE HIF INHIBITOR PREVENTS GLIOMA GROWTH THROUGH BINDING OF PLECTIN-1 AND INHIBITION OF THE HSP90 PATHWAY
Volume: 11 Page(s): 894 - 894
12/01/2009 Authors: Belozerov VE; Kaluz S; Reid S; Mun J; Devi SN; de Noronha R; Moreno C; Brat DL; Goodman M; Nicolaou KC
Identification of a novel small molecule HIF-1alpha translation inhibitor.
Clin Cancer Res Volume: 15 Page(s): 6128 - 6136
10/01/2009 Authors: Narita T; Yin S; Gelin CF; Moreno CS; Yepes M; Nicolaou KC; Van Meir EG
The Emory Biomarker Service Center
BIOMARKERS IN MEDICINE Volume: 3 Page(s): 567 - 571
10/01/2009 Authors: Moreno C; Bouzyk M
Identification of matrix metalloproteinase 7 (MMP7) as a selective biomarker of the triple-negative breast cancer subtype
CANCER RESEARCH Volume: 69
05/01/2009 Authors: Abramovitz M; Catzavelos C; Li Z; Kodani M; Barwick B; Tang W; Dey N; Moreno C; Bouzyk M; Leyland-Jones B
Proteomics analysis of SOX4 reveals posttranslational modifications and novel protein-protein interactions
CANCER RESEARCH Volume: 69
05/01/2009 Authors: Scharer C; Moreno C
Cell line based model to study Wnt-beta catenin pathway in the control of tumor phenotypes in triple negative subset of breast cancer
CANCER RESEARCH Volume: 69
05/01/2009 Authors: Dey N; Kerstann K; De P; Barwick B; Marcus A; Moreno C; Abramovitz M; Bouzyk M; Leyland-Jones B
PROTEIN-CODING AND MICRORNA BIOMARKER GENE PANELS PREDICTIVE OF CLINICAL RECURRENCE IN PROSTATE CANCER
Volume: 181 Page(s): 776 - 776
04/01/2009 Authors: Petros JA; Lai Y-H; Toronto AS; Osunkoya AO; Zhou W; Johnson BA; Toronto RN; Barwick B; Abramovitz M; Bouzyk M
Reduced Rap1 Signaling Is Associated with Prostate Cancer Progression, Migration, Invasion, and Metastasis
FASEB JOURNAL Volume: 23
04/01/2009 Authors: Henderson VM; Osunkoya A; Zhou W; Williams D; Anderson N; Kitayama H; Csete M; Moreno CS
Reduced Rap1 Signaling Is Associated with Prostate Cancer Progression, Migration, Invasion, and Metastasis
FASEB JOURNAL Volume: 23
04/01/2009 Authors: Henderson VM; Osunkoya A; Zhou W; Williams D; Anderson N; Kitayama H; Csete M; Moreno CS
Protein-coding and MicroRNA Biomarker Gene Panels Predictive of Clinical Recurrence in Prostate Cancer
FASEB JOURNAL Volume: 23
04/01/2009 Authors: Moreno CS; Lai Y-H; Seth A; Osunkoya AO; Zhou W; Petros JA; Johnson BA; Nam RK; Barwick BG; Abramovitz M
Molecular differences in triple negative breast cancer between race/ethnicities.
Volume: 69 Page(s): 183S - 183S
01/15/2009 Authors: Bouzyk M; Barwick BG; Abramovitz M; Kodani M; Oprea G; Catzavelos C; Tang W; Moreno CS; Leyland-Jones B
Validation of a custom 512-gene breast cancer panel on the illumina-based DASL mRNA expression platform: focus on triple negative breast tumors using RNA from stored formalin-fixed, paraffin blocks.
Volume: 69 Page(s): 164S - 164S
01/15/2009 Authors: Abramovitz M; Calzavelos C; Li Z; Kodani M; Barwick B; Tang W; Moreno CS; Bouzyk M; Leyland-Jones B
HoxC6 regulation of early mammary epithelial growth and differentiation: implications for breast cancer potential.
Volume: 69 Page(s): 159S - 159S
01/15/2009 Authors: Zhang G; Neumann CA; Moreno CS; Rosenzweig SA; Spyropoulos DD
Differential Wnt pathway activation in triple negative breast cancers comparative to HER2 and hormone positive breast cancers identified from formalin-fixed, paraffin-em bedded tissues
Volume: 69 Page(s): 73S - 74S
01/15/2009 Authors: Barwick BG; Abramovitz M; Tang W; Kodani M; Oprea GM; De PK; Catzavelos C; Bouzyk M; Moreno CS; Leyland-Jones B
Genome-wide promoter analysis of the SOX4 transcriptional network in prostate cancer cells.
Cancer Res Volume: 69 Page(s): 709 - 717
01/15/2009 Authors: Scharer CD; McCabe CD; Ali-Seyed M; Berger MF; Bulyk ML; Moreno CS
RAP1 Signaling in Prostate Cancer Progression
Volume: 22 Page(s): 185A - 185A
01/01/2009 Authors: Moreno CS; Henderson VM; Zhou W; Williams D; Laycock N; Kitayama H; Osunkoya AO
CONSOLIDATION OF THE CANCER EPIGENOME TO REGIONS OF UNIFORM CHROMATIN
Volume: 31 Page(s): 136 - 136
01/01/2009 Authors: Stirzaker C; Song JZ; Statham AL; Robinson M; Lacaze P; Coolen M; Moreno CS; Warren K; Clark SJ
RAP1 Signaling in Prostate Cancer Progression
Volume: 89 Page(s): 185A - 185A
01/01/2009 Authors: Moreno CS; Henderson VM; Zhou W; Williams D; Laycock N; Kitayama H; Osunkoya AO
CONSOLIDATION OF THE CANCER EPIGENOME TO REGIONS OF UNIFORM CHROMATIN
Volume: 31 Page(s): 101 - 101
01/01/2009 Authors: Stirzaker C; Song JZ; Statham AL; Robinson M; Lacaze P; Coolen M; Moreno CS; Warren K; Clark SJ
Aurora kinase inhibitors synergize with paclitaxel to induce apoptosis in ovarian cancer cells.
J Transl Med Volume: 6 Page(s): 79
12/11/2008 Authors: Scharer CD; Laycock N; Osunkoya AO; Logani S; McDonald JF; Benigno BB; Moreno CS
Sox7 Is an independent checkpoint for beta-catenin function in prostate and colon epithelial cells.
Mol Cancer Res Volume: 6 Page(s): 1421 - 1430
09/01/2008 Authors: Guo L; Zhong D; Lau S; Liu X; Dong X-Y; Sun X; Yang VW; Vertino PM; Moreno CS; Varma V
FEEDBACK REGULATION BETWEEN HOW GENES AND ESTROGEN/RTK SIGNALING IN MAMMARY GLAND DEVELOPMENT AND CANCER
ANTICANCER RESEARCH Volume: 28 Page(s): 3494 - 3495
09/01/2008 Authors: Garcia-Gasca A; Neumann CA; Moreno CS; Maroulakou IG; Rosenzweig SA; Spyropoulos DD
Discovery of a novel set of prostate cancer-related genes associated with the prognostically important TMPRSS2:ERG fusion gene
JOURNAL OF CLINICAL ONCOLOGY Volume: 26
05/20/2008 Authors: Abramovitz M; Nam R; Kodani M; Barwick BG; Moreno C; Tang W; Bouzyk M; Seth A; Leyland-Jones B
Genome-wide Analysis of the HOXC6 Transcriptional Network in Prostate Cancer
FASEB JOURNAL Volume: 22
04/01/2008 Authors: Moreno CS; Spyropolous DD; Martin WD; McCabe CD
Genome-wide analysis of the homeobox C6 transcriptional network in prostate cancer.
Cancer Res Volume: 68 Page(s): 1988 - 1996
03/15/2008 Authors: McCabe CD; Spyropoulos DD; Martin D; Moreno CS
Optimization of RNA extraction from FFPE tissues for expression profiling in the DASL assay.
Biotechniques Volume: 44 Page(s): 417 - 423
03/01/2008 Authors: Abramovitz M; Ordanic-Kodani M; Wang Y; Li Z; Catzavelos C; Bouzyk M; Sledge GW; Moreno CS; Leyland-Jones B
Molecular pathogenesis of human prolactinomas identified by gene expression profiling, RT-qPCR, and proteomic analyses.
Pituitary Volume: 11 Page(s): 231 - 245
01/01/2008 Authors: Evans C-O; Moreno CS; Zhan X; McCabe MT; Vertino PM; Desiderio DM; Oyesiku NM
Genomic promoter analysis predicts functional transcription factor binding.
Adv Bioinformatics Volume: 2008 Page(s): 369830
01/01/2008 Authors: Rao JS; Karanam S; McCabe CD; Moreno CS
Novel Molecular Signaling and Classification of Human Clinically Nonfunctioning Pituitary Adenomas Identified by Microarray and Reverse Transcription-Quantitative Polymerase Chain Reaction
Page(s): 263 - 270
01/01/2008 Authors: Evans C-O; Moreno CS; Oyesiku NM
Long range epigenetic silencing (LRES): A common phenomenon in prostate cancer
Volume: 30 Page(s): 225 - 225
01/01/2008 Authors: Coolen M; Song J; Statham AL; Lacaze P; Moreno CS; Kaplan W; Stirzaker C; Clark SJ
A novel HIF inhibitor blocks glioma growth through a non-canonical modulation of the HSP90 pathway
Volume: 9 Page(s): 488 - 489
10/01/2007 Authors: Belozerov VE; Narita T; Mun J; Noronha R; Mao H; Devi S; Wang H; Hill D; Moreno C; Goodman M
The BCL6-associated transcriptional co-repressor, MTA3, is selectively expressed by germinal centre B cells and lymphomas of putative germinal centre derivation.
J Pathol Volume: 213 Page(s): 106 - 115
09/01/2007 Authors: Jaye DL; Iqbal J; Fujita N; Geigerman CM; Li S; Karanam S; Fu K; Weisenburger DD; Chan WC; Moreno CS
Evidence that p53-mediated cell-cycle-arrest inhibits chemotherapeutic treatment of ovarian carcinomas.
PLoS One Volume: 2 Page(s): e441
05/16/2007 Authors: Moreno CS; Matyunina L; Dickerson EB; Schubert N; Bowen NJ; Logani S; Benigno BB; McDonald JF
Reduced rapt signaling contributes to prostate cancer progression
Volume: 21 Page(s): A78 - A78
04/01/2007 Authors: Henderson VM; Ali-Seyed M; Genetta TL; Kitayama H; Csete ME; Moreno CS
Sex-determining region Y box 4 is a transforming oncogene in human prostate cancer cells.
Cancer Res Volume: 66 Page(s): 4011 - 4019
04/15/2006 Authors: Liu P; Ramachandran S; Ali Seyed M; Scharer CD; Laycock N; Dalton WB; Williams H; Karanam S; Datta MW; Jaye DL
Cross-platform expression profiling demonstrates that SV40 small tumor antigen activates Notch, Hedgehog, and Wnt signaling in human cells.
BMC Cancer Volume: 6 Page(s): 54
03/07/2006 Authors: Ali-Seyed M; Laycock N; Karanam S; Xiao W; Blair ET; Moreno CS
Novel molecular signaling and classification of human clinically nonfunctional pituitary adenomas identified by gene expression profiling and proteomic analyses.
Cancer Res Volume: 65 Page(s): 10214 - 10222
11/15/2005 Authors: Moreno CS; Evans C-O; Zhan X; Okor M; Desiderio DM; Oyesiku NM
Molecular classification of renal tumors by gene expression profiling.
J Mol Diagn Volume: 7 Page(s): 206 - 218
05/01/2005 Authors: Schuetz AN; Yin-Goen Q; Amin MB; Moreno CS; Cohen C; Hornsby CD; Yang WL; Petros JA; Issa MM; Pattaras JG
Loss of HOXC6 expression induces apoptosis in prostate cancer cells.
Oncogene Volume: 24 Page(s): 188 - 198
01/06/2005 Authors: Ramachandran S; Liu P; Young AN; Yin-Goen Q; Lim SD; Laycock N; Amin MB; Carney JK; Marshall FF; Petros JA
Nox gene expression in renal cell and prostate carcinoma
Volume: 18 Page(s): 162A - 163A
01/01/2005 Authors: Schuetz AN; Yin-Goen Q; Young AN; Moreno CS; Arnold RS; Amin MB; Petros JA
Nox gene expression in renal cell and prostate carcinoma
Volume: 85 Page(s): 162A - 163A
01/01/2005 Authors: Schuetz AN; Yin-Goen Q; Young AN; Moreno CS; Arnold RS; Amin MB; Petros JA
Novel molecular signaling in human clinically non-functional pituitary adenomas by gene expression profiling analysis
Page(s): 1151 - 1156
01/01/2005 Authors: Evans CO; Moreno CS; Okor M; Oyesiku NM
Signaling and transcriptional changes critical for transformation of human cells by simian virus 40 small tumor antigen or protein phosphatase 2A B56gamma knockdown.
Cancer Res Volume: 64 Page(s): 6978 - 6988
10/01/2004 Authors: Moreno CS; Ramachandran S; Ashby DG; Laycock N; Plattner CA; Chen W; Hahn WC; Pallas DC
CONFAC: automated application of comparative genomic promoter analysis to DNA microarray datasets.
Nucleic Acids Res Volume: 32 Page(s): W475 - W484
07/01/2004 Authors: Karanam S; Moreno CS
MTA3, a Mi-2/NuRD complex subunit, regulates an invasive growth pathway in breast cancer.
Cell Volume: 113 Page(s): 207 - 219
04/18/2003 Authors: Fujita N; Jaye DL; Kajita M; Geigerman C; Moreno CS; Wade PA
Expression microarray analysis of brain tumors: what have we learned so far.
Front Biosci Volume: 7 Page(s): c74 - c82
08/01/2002 Authors: Hunter SB; Moreno CS
Expression profiling of renal epithelial neoplasms: A method for tumor classification and discovery of diagnostic molecular markers (vol 158, pg 1639, 2001)
Volume: 160 Page(s): 2311 - 2311
06/01/2002 Authors: Young AN; Amin MB; Moreno CS; Lim SD; Cohen C; Petros JA; Marshall FF; Neish AS
[Probabilistic models of mortality for patients hospitalized in conventional units].
Med Clin (Barc) Volume: 117 Page(s): 326 - 331
09/29/2001 Authors: Ru M; Roqu M; Sol J; Maci M; Grupo de trabajo de Medida de la gravedad de la Corporaci Sanitria Parc Taul
A mammalian homolog of yeast MOB1 is both a member and a putative substrate of striatin family-protein phosphatase 2A complexes.
J Biol Chem Volume: 276 Page(s): 24253 - 24260
06/29/2001 Authors: Moreno CS; Lane WS; Pallas DC
Expression profiling of renal epithelial neoplasms: a method for tumor classification and discovery of diagnostic molecular markers.
Am J Pathol Volume: 158 Page(s): 1639 - 1651
05/01/2001 Authors: Young AN; Amin MB; Moreno CS; Lim SD; Cohen C; Petros JA; Marshall FF; Neish AS
Carboxymethylation of the PP2A catalytic subunit in Saccharomyces cerevisiae is required for efficient interaction with the B-type subunits Cdc55p and Rts1p.
J Biol Chem Volume: 276 Page(s): 1570 - 1577
01/12/2001 Authors: Wei H; Ashby DG; Moreno CS; Ogris E; Yeong FM; Corbett AH; Pallas DC
Methylation of the protein phosphatase 2A catalytic subunit is essential for association of Balpha regulatory subunit but not SG2NA, striatin, or polyomavirus middle tumor antigen.
Mol Biol Cell Volume: 12 Page(s): 185 - 199
01/01/2001 Authors: Yu XX; Du X; Moreno CS; Green RE; Ogris E; Feng Q; Chou L; McQuoid MJ; Pallas DC
WD40 repeat proteins striatin and S/G(2) nuclear autoantigen are members of a novel family of calmodulin-binding proteins that associate with protein phosphatase 2A.
J Biol Chem Volume: 275 Page(s): 5257 - 5263
02/25/2000 Authors: Moreno CS; Park S; Nelson K; Ashby D; Hubalek F; Lane WS; Pallas DC
CREB regulates MHC class II expression in a CIITA-dependent manner.
Immunity Volume: 10 Page(s): 143 - 151
02/01/1999 Authors: Moreno CS; Beresford GW; Louis-Plence P; Morris AC; Boss JM
Formation of a regulatory factor X/X2 box-binding protein/nuclear factor-Y multiprotein complex on the conserved regulatory regions of HLA class II genes.
J Immunol Volume: 159 Page(s): 3899 - 3909
10/15/1997 Authors: Louis-Plence P; Moreno CS; Boss JM
Regulatory factor X, a bare lymphocyte syndrome transcription factor, is a multimeric phosphoprotein complex.
J Immunol Volume: 158 Page(s): 5841 - 5848
06/15/1997 Authors: Moreno CS; Rogers EM; Brown JA; Boss JM
Purified X2 binding protein (X2BP) cooperatively binds the class II MHC X box region in the presence of purified RFX, the X box factor deficient in the bare lymphocyte syndrome.
J Immunol Volume: 155 Page(s): 4313 - 4321
11/01/1995 Authors: Moreno CS; Emery P; West JE; Durand B; Reith W; Mach B; Boss JM
DNA AFFINITY-PURIFIED X2 BINDING-PROTEIN (X2BP) FORMS A STABILIZED COMPLEX WITH PURIFIED RFX ON MHC CLASS-II PROMOTERS
FASEB JOURNAL Volume: 9 Page(s): A239 - A239
03/09/1995 Authors: MORENO CS; WEST JE; BOSS JM
Molecular analysis of G1B and G3A IFN gamma mutants reveals that defects in CIITA or RFX result in defective class II MHC and Ii gene induction.
Immunity Volume: 1 Page(s): 687 - 697
11/01/1994 Authors: Chin KC; Mao C; Skinner C; Riley JL; Wright KL; Moreno CS; Stark GR; Boss JM; Ting JP
Expression of HLA-A,B,C antigens on primary and metastatic tumor cell populations of human carcinomas.
Cancer Res Volume: 51 Page(s): 6372 - 6380
12/01/1991 Authors: Cordon-Cardo C; Fuks Z; Drobnjak M; Moreno C; Eisenbach L; Feldman M

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Carlos Moreno PhD

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