Publications

• Epidermal growth factor dampens pro-inflammatory gene expression induced by interferon-gamma in global transcriptome analysis of keratinocytes.
  BMC Genomics Volume: 26 Page(s): 122
  02/10/2025 Authors: Gibbs DC; McCrary MR; Moreno CS; Seldin L; Li C; Kamili NAH; Pollack BP
• Obesity reshapes regulatory T cells in the visceral adipose tissue by disrupting cellular cholesterol homeostasis.
  Sci Immunol Volume: 10 Page(s): eadl4909
  01/10/2025 Authors: Elkins C; Ye C; Sivasami P; Mulpur R; Diaz-Saldana PP; Peng A; Xu M; Chiang Y-P; Moll S; Rivera-Rodriguez DE
• Hidradenitis suppurativa: TLSs take the center stage.
  Immunity Volume: 57 Page(s): 2712 - 2714
  12/10/2024 Authors: Elkins C; Li C
• Deciphering visceral adipose tissue regulatory T cells: Key contributors to metabolic health.
  Immunol Rev Volume: 324 Page(s): 52 - 67
  07/01/2024 Authors: Elkins C; Li C
• Obesity-induced dysregulation of skin-resident PPAR+ Treg cells promotes IL-17A-mediated psoriatic inflammation.
  Immunity Volume: 56 Page(s): 1844 - 1861.e6
  08/08/2023 Authors: Sivasami P; Elkins C; Diaz-Saldana PP; Goss K; Peng A; Hamersky M; Bae J; Xu M; Pollack BP; Horwitz EM
• Cytokine and metabolic regulation of adipose tissue Tregs.
  Immunometabolism (Cobham) Volume: 4 Page(s): e00013
  10/01/2022 Authors: Elkins C; Li C
• Interferon--producing plasmacytoid dendritic cells drive the loss of adipose tissue regulatory Tcells during obesity.
  Cell Metab Volume: 33 Page(s): 1610 - 1623.e5
  08/03/2021 Authors: Li C; Wang G; Sivasami P; Ramirez RN; Zhang Y; Benoist C; Mathis D
• PPAR marks splenic precursors of multiple nonlymphoid-tissue Treg compartments.
  Proc Natl Acad Sci U S A Volume: 118
  03/30/2021 Authors: Li C; Muoz-Rojas AR; Wang G; Mann AO; Benoist C; Mathis D
• Discovery of surrogate agonists for visceral fat Treg cells that modulate metabolic indices in vivo.
  Elife Volume: 9
  08/10/2020 Authors: Fernandes RA; Li C; Wang G; Yang X; Savvides CS; Glassman CR; Dong S; Luxenberg E; Sibener LV; Birnbaum ME
• Visceral adipose tissue Tregs and the cells that nurture them.
  Immunol Rev Volume: 295 Page(s): 114 - 125
  05/01/2020 Authors: Li C; Spallanzani RG; Mathis D
• Sex-specific adipose tissue imprinting of regulatory T cells.
  Nature Volume: 579 Page(s): 581 - 585
  03/01/2020 Authors: Vasanthakumar A; Chisanga D; Blume J; Gloury R; Britt K; Henstridge DC; Zhan Y; Torres SV; Liene S; Collins N
• Derivation and Differentiation of Adipose-Tissue Regulatory T Cells: A Stepwise, Multi-Site Process.
  Front Immunol Volume: 11 Page(s): 599277
  01/01/2020 Authors: Sivasami P; Li C
• Distinct immunocyte-promoting and adipocyte-generating stromal components coordinate adipose tissue immune and metabolic tenors.
  Sci Immunol Volume: 4
  05/03/2019 Authors: Spallanzani RG; Zemmour D; Xiao T; Jayewickreme T; Li C; Bryce PJ; Benoist C; Mathis D
• TCR Transgenic Mice Reveal Stepwise, Multi-site Acquisition of the Distinctive Fat-Treg Phenotype.
  Cell Volume: 174 Page(s): 285 - 299.e12
  07/12/2018 Authors: Li C; DiSpirito JR; Zemmour D; Spallanzani RG; Kuswanto W; Benoist C; Mathis D
• Effector CD4(+) T cells can convert to a CD8(+), MHCII-restricted T cell lineage
  Volume: 198
  05/01/2017 Authors: Wong E; Nyanhete T; Frisbee A; Ni Q; Zhang B; Payne T; Liu S; Li C; Chen L; Zhuang Y
• Dissecting adipose tissue Treg differentiation and function in metabolism and obesity-associated cancer using TCR transgenic mice
  Volume: 4
  11/01/2016 Authors: Li C; Benoist C; Mathis D
• MicroRNA-23a Curbs Necrosis during Early T Cell Activation by Enforcing Intracellular Reactive Oxygen Species Equilibrium.
  Immunity Volume: 44 Page(s): 568 - 581
  03/15/2016 Authors: Zhang B; Liu S-Q; Li C; Lykken E; Jiang S; Wong E; Gong Z; Tao Z; Zhu B; Wan Y
• miR-23a supports survival of activated CD4+T cells by maintaining reactive oxygen species equilibrium
  Volume: 194
  05/01/2015 Authors: Liu S; Zhang B; Lin R; Li C; Li Q-J
• Antigen- and cytokine-driven accumulation of regulatory T cells in visceral adipose tissue of lean mice.
  Cell Metab Volume: 21 Page(s): 543 - 557
  04/07/2015 Authors: Kolodin D; van Panhuys N; Li C; Magnuson AM; Cipolletta D; Miller CM; Wagers A; Germain RN; Benoist C; Mathis D
• MeCP2 enforces Foxp3 expression to promote regulatory T cells' resilience to inflammation.
  Proc Natl Acad Sci U S A Volume: 111 Page(s): E2807 - E2816
  07/08/2014 Authors: Li C; Jiang S; Liu S-Q; Lykken E; Zhao L-T; Sevilla J; Zhu B; Li Q-J
• miR-17-92 cluster targets phosphatase and tensin homology and Ikaros Family Zinc Finger 4 to promote TH17-mediated inflammation.
  J Biol Chem Volume: 289 Page(s): 12446 - 12456
  05/02/2014 Authors: Liu S-Q; Jiang S; Li C; Zhang B; Li Q-J
• MeCP2 reinforces STAT3 signaling and the generation of effector CD4+ T cells by promoting miR-124-mediated suppression of SOCS5.
  Sci Signal Volume: 7 Page(s): ra25
  03/11/2014 Authors: Jiang S; Li C; McRae G; Lykken E; Sevilla J; Liu S-Q; Wan Y; Li Q-J
• T cell receptor (TCR) and transforming growth factor (TGF-) signaling converge on DNA (cytosine-5)-methyltransferase to control forkhead box protein 3 (foxp3) locus methylation and inducible regulatory T cell differentiation.
  J Biol Chem Volume: 288 Page(s): 19127 - 19139
  06/28/2013 Authors: Li C; Ebert PJR; Li Q-J
• MeCP2 reinforces STAT3 signaling and effector T cell differentiation by controlling miR-124-mediated suppression of SOCS5 (P1125)
  Volume: 190
  05/01/2013 Authors: Jiang S; Li C; McRae G; Lykken E; Wan Y; Sevilla J; Li Q-J
• MeCP2 enforces Foxp3 expression to determine natural regulatory T cells' resilience to inflammation
  Volume: 190
  05/01/2013 Authors: Li C; Jiang S; Sevilla J; Li Q-J
• miR-126 and miR-126* repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis.
  Nat Cell Biol Volume: 15 Page(s): 284 - 294
  03/01/2013 Authors: Zhang Y; Yang P; Sun T; Li D; Xu X; Rui Y; Li C; Chong M; Ibrahim T; Mercatali L
• Molecular dissection of the miR-17-92 cluster's critical dual roles in promoting Th1 responses and preventing inducible Treg differentiation.
  Blood Volume: 118 Page(s): 5487 - 5497
  11/17/2011 Authors: Jiang S; Li C; Olive V; Lykken E; Feng F; Sevilla J; Wan Y; He L; Li Q-J