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Profile

Carlos Gonzalez Islas PhD

  • Department of Cell Biology
    Instructor
  • (404) 727-1518
  • cegonza@emory.edu
Head shot of Carlos Gonzalez Islas

Academic Appointment

  • Instructor, Emory University School of Medicine

Education

Degrees

  • No Degree from
  • BS from University of Mexico

Research

Focus

  • Developing neural tissue conspicuously shows spontaneous bursts of action potentials that have been postulated contribute to the maturation of the neural networks. My research focuses on understanding how this spontaneous activity contributes to the maturation of the synaptic connectivity in the developing spinal cord.

Publications

  • Homeostatic Regulation of Spike Rate within Bursts in Two Distinct Preparations.
    eNeuro Volume: 11
    09/01/2024 Authors: Lakhani A; Gonzalez-Islas C; Sabra Z; Au Yong N; Wenner P
  • GABAergic synaptic scaling is triggered by changes in spiking activity rather than AMPA receptor activation.
    Elife Volume: 12
    06/28/2024 Authors: Gonzalez-Islas C; Sabra Z; Fong M-F; Yilmam P; Au Yong N; Engisch K; Wenner P
  • The Type 2 Diabetes Factor Methylglyoxal Mediates Axon Initial Segment Shortening and Alters Neuronal Function at the Cellular and Network Levels.
    eNeuro Volume: 8
    01/01/2021 Authors: Griggs RB; Nguyen DVM; Yermakov LM; Jaber JM; Shelby JN; Steinbrunner JK; Miller JA; Gonzalez-Islas C; Wenner P; Susuki K
  • Increased Alcohol Consumption in Mice Lacking Sodium Bicarbonate Transporter NBCn1.
    Sci Rep Volume: 10 Page(s): 11017
    07/03/2020 Authors: Schank JR; Lee S; Gonzalez-Islas CE; Nennig SE; Fulenwider HD; Chang J; Li JM; Kim Y; Jeffers LA; Chung J
  • Homeostatic Recovery of Embryonic Spinal Activity Initiated by Compensatory Changes in Resting Membrane Potential.
    eNeuro Volume: 7
    01/01/2020 Authors: Gonzalez-Islas C; Garcia-Bereguiain MA; Wenner P
  • Deletion of the Na/HCO3 Transporter NBCn1 Protects Hippocampal Neurons from NMDA-induced Seizures and Neurotoxicity in Mice.
    Sci Rep Volume: 9 Page(s): 15981
    11/05/2019 Authors: Park HJ; Gonzalez-Islas CE; Kang Y; Li JM; Choi I
  • Regulation of synaptic scaling by action potential-independent miniature neurotransmission.
    J Neurosci Res Volume: 96 Page(s): 348 - 353
    03/01/2018 Authors: Gonzalez-Islas C; Blow P; Wenner P
  • Elevated intracellular Na+ concentrations in developing spinal neurons.
    J Neurochem Volume: 140 Page(s): 755 - 765
    03/01/2017 Authors: Lindsly C; Gonzalez-Islas C; Wenner P
  • Spontaneous Release Regulates Synaptic Scaling in the Embryonic Spinal Network In Vivo.
    J Neurosci Volume: 36 Page(s): 7268 - 7282
    07/06/2016 Authors: Garcia-Bereguiain MA; Gonzalez-Islas C; Lindsly C; Wenner P
  • Tonic nicotinic transmission enhances spinal GABAergic presynaptic release and the frequency of spontaneous network activity.
    Dev Neurobiol Volume: 76 Page(s): 298 - 312
    03/01/2016 Authors: Gonzalez-Islas C; Garcia-Bereguiain MA; O'Flaherty B; Wenner P
  • Activity blockade and GABAA receptor blockade produce synaptic scaling through chloride accumulation in embryonic spinal motoneurons and interneurons.
    PLoS One Volume: 9 Page(s): e94559
    01/01/2014 Authors: Lindsly C; Gonzalez-Islas C; Wenner P
  • In vivo synaptic scaling is mediated by GluA2-lacking AMPA receptors in the embryonic spinal cord.
    J Neurosci Volume: 33 Page(s): 6791 - 6799
    04/17/2013 Authors: Garcia-Bereguiain MA; Gonzalez-Islas C; Lindsly C; Butler E; Hill AW; Wenner P
  • Tonic and transient endocannabinoid regulation of AMPAergic miniature postsynaptic currents and homeostatic plasticity in embryonic motor networks.
    J Neurosci Volume: 32 Page(s): 13597 - 13607
    09/26/2012 Authors: Gonzalez-Islas C; Garcia-Bereguiain MA; Wenner P
  • GABAergic synaptic scaling in embryonic motoneurons is mediated by a shift in the chloride reversal potential.
    J Neurosci Volume: 30 Page(s): 13016 - 13020
    09/29/2010 Authors: Gonzalez-Islas C; Chub N; Garcia-Bereguiain MA; Wenner P
  • NKCC1 and AE3 appear to accumulate chloride in embryonic motoneurons.
    J Neurophysiol Volume: 101 Page(s): 507 - 518
    02/01/2009 Authors: Gonzalez-Islas C; Chub N; Wenner P
  • Developmental plasticity of inhibitory circuitry.
    J Neurosci Volume: 26 Page(s): 10358 - 10361
    10/11/2006 Authors: Pallas SL; Wenner P; Gonzalez-Islas C; Fagiolini M; Razak KA; Kim G; Sanes D; Roerig B
  • Spontaneous network activity in the embryonic spinal cord regulates AMPAergic and GABAergic synaptic strength.
    Neuron Volume: 49 Page(s): 563 - 575
    02/16/2006 Authors: Gonzalez-Islas C; Wenner P
  • Dopamine enhances spatiotemporal spread of activity in rat prefrontal cortex.
    J Neurophysiol Volume: 93 Page(s): 864 - 872
    02/01/2005 Authors: Bandyopadhyay S; Gonzalez-Islas C; Hablitz JJ
  • Dopamine enhances EPSCs in layer II-III pyramidal neurons in rat prefrontal cortex.
    J Neurosci Volume: 23 Page(s): 867 - 875
    02/01/2003 Authors: Gonzalez-Islas C; Hablitz JJ
  • Dopamine inhibition of evoked IPSCs in rat prefrontal cortex.
    J Neurophysiol Volume: 86 Page(s): 2911 - 2918
    12/01/2001 Authors: Gonzalez-Islas C; Hablitz JJ
  • A ryanodine fluorescent derivative reveals the presence of high-affinity ryanodine binding sites in the Golgi complex of rat sympathetic neurons, with possible functional roles in intracellular Ca(2+) signaling.
    Cell Signal Volume: 13 Page(s): 353 - 362
    05/01/2001 Authors: Cifuentes F; Gonzlez CE; Fiordelisio T; Guerrero G; Lai FA; Hernndez-Cruz A
  • Confocal microscopy in the study of calcium dynamics in living cells.
    Page(s): 671 - 674
    01/01/1998 Authors: Hernandez-Cruz A; Gonzalez-Islas C; Morales MM
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