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Profile

Candace Fleischer

  • Department of Radiology and Imaging Sciences
    Associate Professor
  • candace.fleischer@emory.edu
  • Website

Overview

Dr. Fleischer is a spectroscopist with formal training in physical chemistry and biomedical engineering. Her research group is highly collaborative and focused on the development of new MR spectroscopy and imaging technologies for biomedical and translational applications.

Academic Appointment

  • Associate Professor, Radiology and Imaging Sciences, Emory University School of Medicine
  • Adjunct Assistant Professor, Biomedical Engineering, Georgia Tech and Emory University

Education

Degrees

  • PhD from Georgia Institute of Technology, Atlanta
  • MS from Western Washington University, Bellingham
  • BS from Western Washington University, Bellingham

Research

Publications

  • Coil Combination Using OpTIMUS Results in Improved Signal-to-Noise Ratios of InVivo MR Spectra Acquired at 7T.
    NMR Biomed Volume: 38 Page(s): e70044
    06/01/2025 Authors: Martinez Luque E; Sung D; Risk BB; Goldberg RM; Fleischer CC
  • Reply to "Letter to the Editor - Critical Omissions Compromise Internal Validity in Jugular Vein Compression Collar Studies".
    J Magn Reson Imaging Volume: 61 Page(s): 2348
    05/01/2025 Authors: Fleischer CC; authors of the original manuscript
  • Associations Between Brain Metabolites Measured With MR Spectroscopy and Head Impacts in High School American Football Athletes.
    J Magn Reson Imaging Volume: 61 Page(s): 1738 - 1750
    04/01/2025 Authors: Liu Z; Dudley JA; Diekfuss JA; Ahmed N; Edmondson AD; Cecil KM; Yuan W; Zuleger TM; Slutsky-Ganesh AB; Barber Foss KD
  • Reversal of National Coverage Determination for MR Spectroscopy Increases Reimbursement Rates.
    Radiol Imaging Cancer Volume: 6 Page(s): e240230
    09/01/2024 Authors: Fleischer CC; Lin AP; Allen JW
  • An Update on MR Spectroscopy in Cancer Management: Advances in Instrumentation, Acquisition, and Analysis.
    Radiol Imaging Cancer Volume: 6 Page(s): e230101
    05/01/2024 Authors: Martinez Luque E; Liu Z; Sung D; Goldberg RM; Agarwal R; Bhattacharya A; Ahmed NS; Allen JW; Fleischer CC
  • Ethical Considerations for MRI Research in Human Subjects in the Era of Precision Medicine.
    J Magn Reson Imaging Volume: 59 Page(s): 1864 - 1866
    05/01/2024 Authors: Mao H; Garza-Villarreal EA; Moy L; Hussain T; Scott AD; Lupo JM; Zhou XJ; Fleischer CC
  • Perspective: use and reuse of NMR-based metabolomics data: what works and what remains challenging.
    Metabolomics Volume: 20 Page(s): 41
    03/13/2024 Authors: Gouveia GJ; Head T; Cheng LL; Clendinen CS; Cort JR; Du X; Edison AS; Fleischer CC; Hoch J; Mercaldo N
  • Ethical considerations of preclinical models in imaging research.
    Magn Reson Med Volume: 91 Page(s): 858 - 859
    03/01/2024 Authors: Garza-Villarreal EA; Moy L; Mao H; Hussain T; Lupo JM; Fleischer CC; Scott AD
  • Climate change and neurological diseases: report from the Hot Brain 2: Climate Change and Brain Health meeting, 2024.
    BMJ Neurol Open Volume: 6 Page(s): e000929
    01/01/2024 Authors: Mills JD; Gulcebi MI; Allatt J; Amos A; Atkinson J; Berwick J; Clayton S; Dijk D-J; Doell KC; Ebi K
  • Predicting brain temperature in humans using bioheat models: Progress and outlook.
    J Cereb Blood Flow Metab Volume: 43 Page(s): 833 - 842
    06/01/2023 Authors: Sung D; Rejimon A; Allen JW; Fedorov AG; Fleischer CC
  • Label-Free Chemically and Molecularly Selective Magnetic Resonance Imaging.
    Chem Biomed Imaging Volume: 1 Page(s): 121 - 139
    05/22/2023 Authors: Wu T; Liu C; Thamizhchelvan AM; Fleischer C; Peng X; Liu G; Mao H
  • Association between altered metabolism and genetic mutations in human glioma.
    Cancer Rep (Hoboken) Volume: 6 Page(s): e1799
    05/01/2023 Authors: Pearl H; Fleischer CC
  • Increased adiposity is associated with altered skeletal muscle energetics.
    J Appl Physiol (1985) Volume: 134 Page(s): 1083 - 1092
    05/01/2023 Authors: Reiter DA; Bellissimo MP; Zhou L; Boebinger S; Wells GD; Jones DP; Ziegler TR; Alvarez JA; Fleischer CC
  • Resting-State Brain Temperature: Dynamic Fluctuations in Brain Temperature and the Brain-Body Temperature Gradient.
    J Magn Reson Imaging Volume: 57 Page(s): 1222 - 1228
    04/01/2023 Authors: Sung D; Risk BB; Wang KJ; Allen JW; Fleischer CC
  • Characterization of visual processing in temporomandibular disorders using functional magnetic resonance imaging.
    Brain Behav Volume: 13 Page(s): e2916
    03/01/2023 Authors: Harper DE; Gopinath K; Smith JL; Gregory M; Ichesco E; Aronovich S; Harris RE; Harte SE; Clauw DJ; Fleischer CC
  • Effects of orientation-dependent susceptibility on MR chemical shift brain thermometry.
    Magn Reson Imaging Volume: 95 Page(s): 59 - 62
    01/01/2023 Authors: Wang KJ; Sung D; Risk BB; Allen JW; Fleischer CC
  • Demographic reporting across a decade of neuroimaging: a systematic review.
    Brain Imaging Behav Volume: 16 Page(s): 2785 - 2796
    12/01/2022 Authors: Sterling E; Pearl H; Liu Z; Allen JW; Fleischer CC
  • Comparisons of healthy human brain temperature predicted from biophysical modeling and measured with whole brain MR thermometry.
    Sci Rep Volume: 12 Page(s): 19285
    11/11/2022 Authors: Sung D; Risk BB; Kottke PA; Allen JW; Nahab F; Fedorov AG; Fleischer CC
  • Sex differences in the relationships between body composition, fat distribution, and mitochondrial energy metabolism: a pilot study.
    Nutr Metab (Lond) Volume: 19 Page(s): 37
    05/21/2022 Authors: Bellissimo MP; Fleischer CC; Reiter DA; Goss AM; Zhou L; Smith MR; Kohlmeier J; Tirouvanziam R; Tran PH; Hao L
  • Topology of pain networks in patients with temporomandibular disorder and pain-free controls with and without concurrent experimental pain: A pilot study.
    Front Pain Res (Lausanne) Volume: 3 Page(s): 966398
    01/01/2022 Authors: Smith JL; Allen JW; Fleischer CC; Harper DE
  • Glutamine Imaging: A New Avenue for Glioma Management.
    AJNR Am J Neuroradiol Volume: 43 Page(s): 11 - 18
    01/01/2022 Authors: Ekici S; Nye JA; Neill SG; Allen JW; Shu H-K; Fleischer CC
  • Relationships between frontal metabolites and Alzheimer's disease biomarkers in cognitively normal older adults.
    Neurobiol Aging Volume: 109 Page(s): 22 - 30
    01/01/2022 Authors: Hone-Blanchet A; Bohsali A; Krishnamurthy LC; Shahid S; Lin Q; Zhao L; Loring D; Goldstein F; John SE; Fleischer CC
  • Nutritional Metabolomics of Skeletal Muscle and Monocyte Mitochondrial Function
    OBESITY Volume: 29 Page(s): 130 - 131
    12/01/2021 Authors: Bellissimo M; Taibl K; Fleischer C; Reiter D; Zhou L; Smith MR; Wells G; Jones D; Hundley WG; Ziegler T
  • Changes in brain metabolites and resting-state connectivity in collegiate basketball players as a function of play time.
    J Neuroimaging Volume: 31 Page(s): 1146 - 1155
    11/01/2021 Authors: Sung D; Smith JL; Yarabarla S; Prasad O; Owusu-Ansah M; Ekici S; Allen JW; Mines B; Fleischer CC
  • Characterization of dysregulated glutamine metabolism in human glioma tissue with 1H NMR.
    Sci Rep Volume: 10 Page(s): 20435
    11/24/2020 Authors: Ekici S; Risk BB; Neill SG; Shu H-K; Fleischer CC
  • Optimized truncation to integrate multi-channel MRS data using rank-R singular value decomposition.
    NMR Biomed Volume: 33 Page(s): e4297
    07/01/2020 Authors: Sung D; Risk BB; Owusu-Ansah M; Zhong X; Mao H; Fleischer CC
  • Traumatic Brain Injury Results in Dynamic Brain Structure Changes Leading to Acute and Chronic Motor Function Deficits in a Pediatric Piglet Model.
    J Neurotrauma Volume: 36 Page(s): 2930 - 2942
    10/15/2019 Authors: Kinder HA; Baker EW; Wang S; Fleischer CC; Howerth EW; Duberstein KJ; Mao H; Platt SR; West FD
  • Improved fitting of HRMAS NMR spectra for ex vivo metabolomic analysis of glioma tissue
    Volume: 79
    07/01/2019 Authors: Ekici S; Geryak R; Neill SG; Shu H-K; Fleischer CC
  • Mitochondrial Bioenergetic Metabolism Is Associated with Total Body Composition and Influenced by Normal Weight Obesity (P21-039-19).
    Curr Dev Nutr Volume: 3
    06/01/2019 Authors: Bellissimo M; Fleischer C; Tran P; Hao L; Reiter D; Smith M; Boebinger S; Wells G; Jones D; Ziegler T
  • Bulk Flow and Near Wall Hemodynamics of the Rabbit Aortic Arch and Descending Thoracic Aorta: A 4D PC-MRI Derived Computational Fluid Dynamics Study.
    J Biomech Eng Volume: 141 Page(s): 0110031 - 01100311
    01/01/2019 Authors: Molony DS; Park J; Zhou L; Fleischer CC; Sun HY; Hu XP; Oshinski JN; Samady H; Giddens DP; Rezvan A
  • Effects of proximity and noise level of phased array coil elements on overall signal-to-noise in parallel MR spectroscopy.
    Magn Reson Imaging Volume: 47 Page(s): 125 - 130
    04/01/2018 Authors: Fleischer CC; Zhong X; Mao H
  • Impact of Anti-Biofouling Surface Coatings on the Properties of Nanomaterials and Their Biomedical Applications.
    J Mater Chem B Volume: 6 Page(s): 9 - 24
    01/07/2018 Authors: Li Y; Xu Y; Fleischer CC; Huang J; Lin R; Yang L; Mao H
  • The Brain Thermal Response as a Potential Neuroimaging Biomarker of Cerebrovascular Impairment.
    AJNR Am J Neuroradiol Volume: 38 Page(s): 2044 - 2051
    11/01/2017 Authors: Fleischer CC; Wu J; Qiu D; Park S-E; Nahab F; Dehkharghani S
  • Cerebral Temperature Dysregulation: MR Thermographic Monitoring in a Nonhuman Primate Study of Acute Ischemic Stroke.
    AJNR Am J Neuroradiol Volume: 38 Page(s): 712 - 720
    04/01/2017 Authors: Dehkharghani S; Fleischer CC; Qiu D; Yepes M; Tong F
  • Conceptual convergence: increased inflammation is associated with increased basal ganglia glutamate in patients with major depression.
    Mol Psychiatry Volume: 21 Page(s): 1351 - 1357
    10/01/2016 Authors: Haroon E; Fleischer CC; Felger JC; Chen X; Woolwine BJ; Patel T; Hu XP; Miller AH
  • Proton resonance frequency chemical shift thermometry: experimental design and validation toward high-resolution noninvasive temperature monitoring and in vivo experience in a nonhuman primate model of acute ischemic stroke.
    AJNR Am J Neuroradiol Volume: 36 Page(s): 1128 - 1135
    06/01/2015 Authors: Dehkharghani S; Mao H; Howell L; Zhang X; Pate KS; Magrath PR; Tong F; Wei L; Qiu D; Fleischer C
  • Secondary structure of corona proteins determines the cell surface receptors used by nanoparticles.
    J Phys Chem B Volume: 118 Page(s): 14017 - 14026
    12/11/2014 Authors: Fleischer CC; Payne CK
  • Nanoparticle-cell interactions: molecular structure of the protein corona and cellular outcomes.
    Acc Chem Res Volume: 47 Page(s): 2651 - 2659
    08/19/2014 Authors: Fleischer CC; Payne CK
  • Cellular Binding of Anionic Nanoparticles is Inhibited by Serum Proteins Independent of Nanoparticle Composition.
    Biomater Sci Volume: 1 Page(s): 975 - 982
    09/01/2013 Authors: Fleischer CC; Kumar U; Payne CK
  • Nanoparticle surface charge mediates the cellular receptors used by protein-nanoparticle complexes.
    J Phys Chem B Volume: 116 Page(s): 8901 - 8907
    08/02/2012 Authors: Fleischer CC; Payne CK
  • Featured Cover
    NMR IN BIOMEDICINE Volume: 33
    Authors: Fleischer CC; Sung D; Risk BB; Owusu-Ansah M; Zhong X; Mao H
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