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Profile

Blerta Xhemalce

  • Department of Biochemistry
    Associate Professor
  • (404) 727-9745
  • blerta.xhemalce@emory.edu

Research

Publications

  • NAT10 and N4-acetylcytidine restrain R-loop levels and related inflammatory responses.
    Sci Adv Volume: 11 Page(s): eads6144
    03/28/2025 Authors: Debnath TK; Abell NS; Li Y-R; Devanathan SK; Navedo E; Xhemale B
  • Epitranscriptome in action: RNA modifications in the DNA damage response.
    Mol Cell Volume: 84 Page(s): 3610 - 3626
    10/03/2024 Authors: Xhemale B; Miller KM; Gromak N
  • ChemRAP uncovers specific mRNA translation regulation via RNA 5' phospho-methylation.
    EMBO Rep Volume: 25 Page(s): 1570 - 1588
    03/01/2024 Authors: Ipas H; Gouws EB; Abell NS; Chiou P-C; Devanathan SK; Herv S; Lee S; Mercado M; Reinsborough C; Halabelian L
  • The Ribosome Assembly Factor LSG1 Interacts with Vesicle-Associated Membrane Protein-Associated Proteins (VAPs).
    Mol Cell Biol Volume: 44 Page(s): 345 - 357
    01/01/2024 Authors: Sutjita P; Musalgaonkar S; Recchia-Rife J; Huang L; Xhemalce B; Johnson AW
  • Poly(ADP-ribose) binding and macroH2A mediate recruitment and functions of KDM5A at DNA lesions.
    J Cell Biol Volume: 220
    07/05/2021 Authors: Kumbhar R; Sanchez A; Perren J; Gong F; Corujo D; Medina F; Devanathan SK; Xhemalce B; Matouschek A; Buschbeck M
  • BCDIN3D RNA methyltransferase stimulates Aldolase C expression and glycolysis through let-7 microRNA in breast cancer cells.
    Oncogene Volume: 40 Page(s): 2395 - 2406
    04/01/2021 Authors: Reinsborough CW; Ipas H; Abell NS; Gouws EB; Williams JP; Mercado M; Van Den Berg C; Xhemale B
  • Biological functions of RNA modifications.
    Brief Funct Genomics Volume: 20 Page(s): 75 - 76
    03/27/2021 Authors: Xhemale B
  • Deciphering RNA modifications at base resolution: from chemistry to biology.
    Brief Funct Genomics Volume: 20 Page(s): 77 - 85
    03/27/2021 Authors: Debnath TK; Xhemale B
  • Post-transcriptional regulation of antiviral gene expression by N6-methyladenosine.
    Cell Rep Volume: 34 Page(s): 108798
    03/02/2021 Authors: McFadden MJ; McIntyre ABR; Mourelatos H; Abell NS; Gokhale NS; Ipas H; Xhemale B; Mason CE; Horner SM
  • Facile detection of RNA phospho-methylation in cells and tissues.
    Volume: 658 Page(s): 49 - 72
    01/01/2021 Authors: Devanathan SK; Debnath TK; Xhemale B
  • Making it or breaking it: DNA methylation and genome integrity.
    Volume: 64 Page(s): 687 - 703
    10/26/2020 Authors: Sriraman A; Debnath TK; Xhemalce B; Miller KM
  • PCAF-Mediated Histone Acetylation Promotes Replication Fork Degradation by MRE11 and EXO1 in BRCA-Deficient Cells.
    Mol Cell Volume: 80 Page(s): 327 - 344.e8
    10/15/2020 Authors: Kim JJ; Lee SY; Choi J-H; Woo HG; Xhemalce B; Miller KM
  • Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.
    Genes Dev Volume: 33 Page(s): 1751 - 1774
    12/01/2019 Authors: Kim JJ; Lee SY; Gong F; Battenhouse AM; Boutz DR; Bashyal A; Refvik ST; Chiang C-M; Xhemalce B; Paull TT
  • Antibody-Free Assay for RNA Methyltransferase Activity Analysis.
    J Vis Exp
    07/09/2019 Authors: Shelton SB; Xhemalce B
  • BCDIN3D regulates tRNAHis 3' fragment processing.
    PLoS Genet Volume: 15 Page(s): e1008273
    07/01/2019 Authors: Reinsborough CW; Ipas H; Abell NS; Nottingham RM; Yao J; Devanathan SK; Shelton SB; Lambowitz AM; Xhemale B
  • Deletion of the neural tube defect-associated gene Mthfd1l disrupts one-carbon and central energy metabolism in mouse embryos.
    J Biol Chem Volume: 293 Page(s): 5821 - 5833
    04/20/2018 Authors: Bryant JD; Sweeney SR; Sentandreu E; Shin M; Ipas H; Xhemalce B; Momb J; Tiziani S; Appling DR
  • Crosstalk between the RNA Methylation and Histone-Binding Activities of MePCE Regulates P-TEFb Activation on Chromatin.
    Cell Rep Volume: 22 Page(s): 1374 - 1383
    02/06/2018 Authors: Shelton SB; Shah NM; Abell NS; Devanathan SK; Mercado M; Xhemale B
  • Chromatin Regulates Genome Targeting with Cisplatin.
    Angew Chem Int Ed Engl Volume: 56 Page(s): 6483 - 6487
    06/01/2017 Authors: Zacharioudakis E; Agarwal P; Bartoli A; Abell N; Kunalingam L; Bergoglio V; Xhemalce B; Miller KM; Rodriguez R
  • Click Quantitative Mass Spectrometry Identifies PIWIL3 as a Mechanistic Target of RNA Interference Activator Enoxacin in Cancer Cells.
    J Am Chem Soc Volume: 139 Page(s): 1400 - 1403
    02/01/2017 Authors: Abell NS; Mercado M; Caeque T; Rodriguez R; Xhemalce B
  • Who Watches the Watchmen: Roles of RNA Modifications in the RNA Interference Pathway.
    PLoS Genet Volume: 12 Page(s): e1006139
    07/01/2016 Authors: Shelton SB; Reinsborough C; Xhemalce B
  • ATM regulation of IL-8 links oxidative stress to cancer cell migration and invasion.
    Elife Volume: 4
    06/01/2015 Authors: Chen W-T; Ebelt ND; Stracker TH; Xhemalce B; Van Den Berg CL; Miller KM
  • 3D-printed microfluidic microdissector for high-throughput studies of cellular aging.
    Anal Chem Volume: 86 Page(s): 7406 - 7412
    08/05/2014 Authors: Spivey EC; Xhemalce B; Shear JB; Finkelstein IJ
  • From histones to RNA: role of methylation in cancer.
    Brief Funct Genomics Volume: 12 Page(s): 244 - 253
    05/01/2013 Authors: Xhemalce B
  • Human RNA methyltransferase BCDIN3D regulates microRNA processing.
    Cell Volume: 151 Page(s): 278 - 288
    10/12/2012 Authors: Xhemalce B; Robson SC; Kouzarides T
  • Three distinct patterns of histone H3Y41 phosphorylation mark active genes.
    Cell Rep Volume: 2 Page(s): 470 - 477
    09/27/2012 Authors: Dawson MA; Foster SD; Bannister AJ; Robson SC; Hannah R; Wang X; Xhemalce B; Wood AD; Green AR; Gttgens B
  • Small-molecule-induced DNA damage identifies alternative DNA structures in human genes.
    Nat Chem Biol Volume: 8 Page(s): 301 - 310
    02/05/2012 Authors: Rodriguez R; Miller KM; Forment JV; Bradshaw CR; Nikan M; Britton S; Oelschlaegel T; Xhemalce B; Balasubramanian S; Jackson SP
  • Nucleosome-interacting proteins regulated by DNA and histone methylation.
    Cell Volume: 143 Page(s): 470 - 484
    10/29/2010 Authors: Bartke T; Vermeulen M; Xhemalce B; Robson SC; Mann M; Kouzarides T
  • A chromodomain switch mediated by histone H3 Lys 4 acetylation regulates heterochromatin assembly.
    Genes Dev Volume: 24 Page(s): 647 - 652
    04/01/2010 Authors: Xhemalce B; Kouzarides T
  • Regulation of histone H3 lysine 56 acetylation in Schizosaccharomyces pombe.
    J Biol Chem Volume: 282 Page(s): 15040 - 15047
    05/18/2007 Authors: Xhemalce B; Miller KM; Driscoll R; Masumoto H; Jackson SP; Kouzarides T; Verreault A; Arcangioli B
  • Role of SUMO in the dynamics of telomere maintenance in fission yeast.
    Proc Natl Acad Sci U S A Volume: 104 Page(s): 893 - 898
    01/16/2007 Authors: Xhemalce B; Riising EM; Baumann P; Dejean A; Arcangioli B; Seeler J-S
  • Role of the fission yeast SUMO E3 ligase Pli1p in centromere and telomere maintenance.
    EMBO J Volume: 23 Page(s): 3844 - 3853
    10/01/2004 Authors: Xhemalce B; Seeler J-S; Thon G; Dejean A; Arcangioli B
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