Brian Robinson
- Department of Pathology and Laboratory Medicine
Assistant Professor
- (404) 727-0988
- bsrobin@emory.edu
- @brobinsonGIpath
Overview
Gastrointestinal and Liver Pathology
Robinson, Brian S. (MD, PhD) is an Assistant Professor in the Department of Pathology and Laboratory Medicine, and works as a Gastrointestinal Pathologist in Emorys Division of Anatomic Pathology. His lab is focused on understanding how developmental signaling pathways, particularly ROS-related signaling pathways, influence intestinal epithelial homeostasis and contribute to tumorigenesis. Moreover, Dr. Robinson is interested in identifying mechanisms by which host microbial populations activate these cellular pathways, as well as, identifying novel effectors of tissue restitution in metazoans. Dr. Robinson recently received the Clinician Scientist Developmental Award from the American Cancer Society to investigate a novel proliferative checkpoint between the redox-sensitive transcription factor Nrf2 and proliferative phenotypes in the murine intestine. His lab utilizes a wide variety of cellular, molecular, genetic, and translational techniques, including using the model organism Drosophila to identify conserved cellular pathways across metazoans.
Academic Appointment
- Assistant Professor, Pathology and Laboratory Medicine, Emory University, School of Medicine
Education
Degrees
- MD/PhD from Emory University
Research
Publications
-
Targeting altered glycosylation in secreted tumor glycoproteins for broad cancer detection.
Glycobiology Volume: 33 Page(s): 567 - 578
08/14/2023 Authors: Kudelka MR; Gu W; Matsumoto Y; Ju T; Barnes Ii RH; Kardish RJ; Heimburg-Molinaro J; Lehoux S; Zeng J; Cohen C -
NSD2 maintains lineage plasticity and castration-resistance in neuroendocrine prostate cancer.
bioRxiv
07/19/2023 Authors: Li JJ; Vasciaveo A; Karagiannis D; Sun Z; Chen X; Socciarelli F; Frankenstein Z; Zou M; Pannellini T; Chen Y -
Dual IL-6 and CTLA-4 blockade regresses pancreatic tumors in a T cell- and CXCR3-dependent manner.
JCI Insight Volume: 8
04/24/2023 Authors: Ware MB; Phillips M; McQuinn C; Zaidi MY; Knochelmann HM; Greene E; Robinson B; Herting CJ; Mace TA; Chen Z -
Malignant undifferentiated and rhabdoid tumors of the gastroesophageal junction and esophagus with SMARCA4 loss: a case series.
Volume: 134 Page(s): 56 - 65
04/01/2023 Authors: Gupta S; Noona SW; Pambuccian SE; Robinson B; Martin LW; Williams E; Stelow EB; Raghavan SS -
Analysis of KRAS Mutations in Gastrointestinal Tract Adenocarcinomas Reveals Site-Specific Mutational Signatures.
Mod Pathol Volume: 36 Page(s): 100014
02/01/2023 Authors: Wang L; Saeedi BJ; Mahdi Z; Krasinskas A; Robinson B -
Oxidative stress mediates end-organ damage in a novel model of acetaminophen-toxicity in Drosophila.
Sci Rep Volume: 12 Page(s): 19309
11/11/2022 Authors: Saeedi BJ; Hunter-Chang S; Luo L; Li K; Liu KH; Robinson BS -
Targeting vasoactive intestinal peptide-mediated signaling enhances response to immune checkpoint therapy in pancreatic ductal adenocarcinoma.
Nat Commun Volume: 13 Page(s): 6418
10/27/2022 Authors: Ravindranathan S; Passang T; Li J-M; Wang S; Dhamsania R; Ware MB; Zaidi MY; Zhu J; Cardenas M; Liu Y -
The -galactoside binding lectin Galectin regulates metabolism in Drosophila.
FASEB J Volume: 36 Suppl 1
05/01/2022 Authors: Luo L; Robinson B -
Malignant Undifferentiated and Rhabdoid Tumors of the Gastroesophageal Junction and Esophagus with SMARCA4 Loss
Volume: 101 Page(s): 415 - 416
03/01/2021 Authors: Gupta S; Pambuccian S; Robinson B; Stelow E -
Correlation of Unique Histologic Features of Colorectal Adenocarcinoma with Clinical and Molecular Outcomes, an Exploration of the TCGA Dataset
Volume: 101 Page(s): 381 - 382
03/01/2021 Authors: Anderson J; Mahdi Z; Krasinskas A; Robinson B