Bo Liang
- Department of Biochemistry
Associate Professor
- (404) 727-8287
- bo.liang@emory.edu
- Lab website
- PubMed
- Google Scholar
-
Emory University
Department of Biochemistry
1510 Clifton Road NE, RM G247
Overview
The principal goal of our research is to scrutinize high-resolution structural details and to understand the molecular mechanisms of large assemblies, including ribonucleoprotein complexes and membrane proteins using integrated approaches of cryo-EM, x-ray crystallography and fluorescence light microscopy.
Academic Appointment
- Associate Professor, Department of Biochemistry, Emory University School of Medicine
Education
Degrees
- PhD from Florida State University
- Bachelor of Science from University of Science and Technology of China
- Bachelor of Engineering from University of Science and Technology of China
Research
Publications
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SMARCB1 missense mutants disrupt SWI/SNF complex stability and remodeling activity.
03/26/2025 Authors: Cooper GW; Lee BP; Kim WJ; Su Y; Chen VZ; Salas E; Yang X; Lintner RE; Piccioni F; Giacomelli AO -
Structural basis of collagen glucosyltransferase function and its serendipitous role in kojibiose synthesis.
Res Sq
01/29/2025 Authors: Kim JS; Chen Z; Garcia SAE; Buhlheller C; Richards SJ; Chen T; Wu J; Bruntz RC; Gilliam ME; Yamauchi M -
Biochemical simulation of mutation synthesis and repair during SARS-CoV-2 RNA polymerization.
Virology Volume: 600 Page(s): 110255
12/01/2024 Authors: Oo A; Chen Z; Cao D; Cho Y-J; Liang B; Schinazi RF; Kim B -
In vitro higher-order oligomeric assembly of the respiratory syncytial virus M2-1 protein with longer RNAs.
J Virol Volume: 98 Page(s): e0104624
08/20/2024 Authors: Gao Y; Raghavan A; Espinosa Garcia SA; Deng B; Hurtado de Mendoza D; Liang B -
Structures of the promoter-bound respiratory syncytial virus polymerase.
Nature Volume: 625 Page(s): 611 - 617
01/01/2024 Authors: Cao D; Gao Y; Chen Z; Gooneratne I; Roesler C; Mera C; D'Cunha P; Antonova A; Katta D; Romanelli S -
Structural basis of the American mink ACE2 binding by Y453F trimeric spike glycoproteins of SARS-CoV-2.
J Med Virol Volume: 95 Page(s): e29163
10/01/2023 Authors: Ahn H; Calderon BM; Fan X; Gao Y; Horgan NL; Jiang N; Blohm DS; Hossain J; Rayyan NWK; Osman SH -
In Silico Identification and In Vitro Validation of Repurposed Compounds Targeting the RSV Polymerase.
Microorganisms Volume: 11
06/18/2023 Authors: Xu E; Park S; Calderon J; Cao D; Liang B -
PEBAT, an Intriguing Neurodegenerative Tubulinopathy Caused by a Novel Homozygous Variant in TBCD: A Case Series and Literature Review.
Pediatr Neurol Volume: 139 Page(s): 59 - 64
02/01/2023 Authors: Ocampo-Chih C; Dennis H; Lall N; Pham N; Liang B; Verma S; Neira Fresneda J -
Optimal Conditions for In Vitro Assembly of Respiratory Syncytial Virus Nucleocapsid-like Particles.
Viruses Volume: 15
01/25/2023 Authors: Gao Y; Raghavan A; Deng B; Lee J; Liang B -
An RSV Live-Attenuated Vaccine Candidate Lacking G Protein Mucin Domains Is Attenuated, Immunogenic, and Effective in Preventing RSV in BALB/c Mice.
J Infect Dis Volume: 227 Page(s): 50 - 60
12/28/2022 Authors: Roe MK; Perez MA; Hsiao H-M; Lapp SA; Sun H-Y; Jadhao S; Young AR; Batista YS; Reed RC; Taz A