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Profile

Benjamin Barwick Ph.D.

  • Department of Hematology and Medical Oncology
    Assistant Professor
  • (404) 727-5320
  • bbarwic@emory.edu
Head shot of Benjamin Barwick

Academic Appointment

  • Assistant Professor, Department of Hematology and Medical Oncology, Emory University School of Medicine

Education

Degrees

  • PhD from Emory University School of Medicine
  • MS from Georgia Institute of Technology

Research

Publications

  • Targeting high-risk multiple myeloma genotypes with optimized anti-CD70 CAR-T cells.
    Blood
    05/13/2025 Authors: Kasap C; Izgutdina A; Patio-Escobar B; Kang AS; Chilakapati N; Akagi N; Manoj AM; Johnson H; Rashid T; Werner J
  • Heme promotes venetoclax resistance in multiple myeloma through MEK-ERK signaling and purine biosynthesis.
    Blood Volume: 145 Page(s): 732 - 747
    02/13/2025 Authors: Nair R; Vu AH; Freer AK; Bhatia KS; Wang D; Savani MR; Matulis SM; Lonial S; Jaye DL; Boise LH
  • Predictors of response to venetoclax and therapeutic potential of CDK7 inhibition in multiple myeloma.
    Blood Neoplasia Volume: 1 Page(s): 100049
    12/01/2024 Authors: Dutta RP; Thibaud S; Leshchenko V; Ram M; Melnekoff DT; Bhalla S; Restrepo P; Gupta VA; Barwick BG; Newman S
  • KDM6A regulates immune response genes in multiple myeloma.
    Blood Volume: 144 Page(s): 1508 - 1520
    10/03/2024 Authors: Dupr-Richer D; Riva A; Barwick BG; Maji S; Casellas Romn H; Li J; De U; Sobh A; Quickstad G; Piper C
  • The epigenetic spectrum of IgM gammopathies.
    Blood Volume: 144 Page(s): 1240 - 1241
    09/19/2024 Authors: Barwick BG
  • Functional multiomics reveals genetic and pharmacologic regulation of surface CD38 in multiple myeloma.
    Blood Neoplasia Volume: 1 Page(s): 100025
    09/01/2024 Authors: Choudhry P; Kasap C; Patio-Escobar B; Gugliemini O; Geng H; Sarin V; Kang A; Kishishita A; Rampersaud S; Sarah L
  • NSD2 drives t(4;14) myeloma cell dependence on adenylate kinase 2 by diverting one-carbon metabolism to the epigenome.
    Blood Volume: 144 Page(s): 283 - 295
    07/18/2024 Authors: Sobh A; Encinas E; Patel A; Surapaneni G; Bonilla E; Kaestner C; Poullard J; Clerio M; Vasan K; Freeman T
  • Interruption of KLF5 acetylation promotes PTEN-deficient prostate cancer progression by reprogramming cancer-associated fibroblasts.
    J Clin Invest Volume: 134
    05/23/2024 Authors: Zhang B; Liu M; Mai F; Li X; Wang W; Huang Q; Du X; Ding W; Li Y; Barwick BG
  • Targeting high-risk multiple myeloma genotypes with optimized anti-CD70 CAR-T cells.
    bioRxiv
    02/28/2024 Authors: Kasap C; Izgutdina A; Patio-Escobar B; Kang A; Chilakapati N; Akagi N; Johnson H; Rashid T; Werner J; Barpanda A
  • KDM6A Regulates Immune Response Genes in Multiple Myeloma.
    bioRxiv
    02/12/2024 Authors: Dupr-Richer D; Riva A; Maji S; Barwick BG; Romn HC; Sobh A; Quickstad G; Li J; De U; Piper C
  • Transcriptional Heterogeneity Overcomes Super-Enhancer Disrupting Drug Combinations in Multiple Myeloma.
    Blood Cancer Discov Volume: 5 Page(s): 34 - 55
    01/08/2024 Authors: Welsh SJ; Barwick BG; Meermeier EW; Riggs DL; Shi C-X; Zhu YX; Sharik ME; Du MT; Abrego Rocha LD; Garbitt VM
  • ETV4-Dependent Transcriptional Plasticity Maintains MYC Expression and Results in IMiD Resistance in Multiple Myeloma.
    Blood Cancer Discov Volume: 5 Page(s): 56 - 73
    01/08/2024 Authors: Neri P; Barwick BG; Jung D; Patton JC; Maity R; Tagoug I; Stein CK; Tilmont R; Leblay N; Ahn S
  • Integrated epigenetic and transcriptional single-cell analysis of t(11;14) multiple myeloma and its BCL2 dependency.
    Blood Volume: 143 Page(s): 42 - 56
    01/04/2024 Authors: Leblay N; Ahn S; Tilmont R; Poorebrahim M; Maity R; Lee H; Barakat E; Alberge J-B; Sinha S; Jaffer A
  • Integrated Genomic Analysis of Primary Prostate Tumor Foci and Corresponding Lymph Node Metastases Identifies Mutations and Pathways Associated with Metastasis.
    Cancers (Basel) Volume: 15
    11/30/2023 Authors: Moreno CS; Winham CL; Alemozaffar M; Klein ER; Lawal IO; Abiodun-Ojo OA; Patil D; Barwick BG; Huang Y; Schuster DM
  • Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias.
    Nat Cancer Volume: 4 Page(s): 754 - 773
    05/01/2023 Authors: de Matos Simoes R; Shirasaki R; Downey-Kopyscinski SL; Matthews GM; Barwick BG; Gupta VA; Dupr-Richer D; Yamano S; Hu Y; Sheffer M
  • CD8+ Tcell activation in cancer comprises an initial activation phase in lymph nodes followed by effector differentiation within the tumor.
    Immunity Volume: 56 Page(s): 107 - 124.e5
    01/10/2023 Authors: Prokhnevska N; Cardenas MA; Valanparambil RM; Sobierajska E; Barwick BG; Jansen C; Reyes Moon A; Gregorova P; delBalzo L; Greenwald R
  • Inhibition of NADPH Oxidase-ROS Signal using Hyaluronic Acid Nanoparticles for Overcoming Radioresistance in Cancer Therapy.
    ACS Nano Volume: 16 Page(s): 18708 - 18728
    11/22/2022 Authors: Zhu L; Zhao Y; Liu T; Chen M; Qian WP; Jiang B; Barwick BG; Zhang L; Styblo TM; Li X
  • Therapeutic implications of mitochondrial stress-induced proteasome inhibitor resistance in multiple myeloma.
    Sci Adv Volume: 8 Page(s): eabq5575
    09/30/2022 Authors: Sharma A; Nair R; Achreja A; Mittal A; Gupta P; Balakrishnan K; Edgar CL; Animasahun O; Dwivedi B; Barwick BG
  • adrenergic signaling regulates hematopoietic stem and progenitor cell commitment and therapy sensitivity in multiple myeloma.
    Haematologica Volume: 107 Page(s): 2226 - 2231
    09/01/2022 Authors: Nair R; Subramaniam V; Barwick BG; Gupta VA; Matulis SM; Lonial S; Boise LH; Nooka AK; Muthumalaiappan K; Shanmugam M
  • Venetoclax ex vivo functional profiling predicts improved progression-free survival.
    Blood Cancer J Volume: 12 Page(s): 115
    08/04/2022 Authors: Gupta VA; Matulis SM; Barwick BG; Bog RD; Shebelut CW; Shanmugam M; Neri P; Bahlis NJ; Dhodapkar MV; Heffner LT
  • PDZ Proteins SCRIB and DLG1 Regulate Myeloma Cell Surface CD86 Expression, Growth, and Survival.
    Mol Cancer Res Volume: 20 Page(s): 1122 - 1136
    07/06/2022 Authors: Moser-Katz T; Gavile CM; Barwick BG; Lee KP; Boise LH
  • Multivariant Transcriptome Analysis Identifies Modules and Hub Genes Associated with Poor Outcomes in Newly Diagnosed Multiple Myeloma Patients.
    Cancers (Basel) Volume: 14
    04/29/2022 Authors: Adebayo OO; Dammer EB; Dill CD; Adebayo AO; Oseni SO; Griffen TL; Ohandjo AQ; Yan F; Jain S; Barwick BG
  • Urolithiasis/Endourology.
    J Urol Volume: 206 Page(s): 1321 - 1324
    11/01/2021 Authors: Assimos DG
  • Aberrant Extrafollicular B Cells, Immune Dysfunction, Myeloid Inflammation, and MyD88-Mutant Progenitors Precede Waldenstrom Macroglobulinemia.
    Blood Cancer Discov Volume: 2 Page(s): 600 - 615
    11/01/2021 Authors: Kaushal A; Nooka AK; Carr AR; Pendleton KE; Barwick BG; Manalo J; McCachren SS; Gupta VA; Joseph NS; Hofmeister CC
  • PDZ proteins, SCRIB and DLG1, regulate CD86 surface expression, myeloma growth, and survival
    Volume: 21 Page(s): S79 - S79
    10/01/2021 Authors: Moser-Katz T; Gavile C; Barwick B; Lee K; Boise L
  • Whole-genome analysis of TET dioxygenase function in regulatory T cells.
    EMBO Rep Volume: 22 Page(s): e52716
    08/04/2021 Authors: Yue X; Samaniego-Castruita D; Gonzlez-Avalos E; Li X; Barwick BG; Rao A
  • Venetoclax sensitivity in multiple myeloma is associated with B-cell gene expression.
    Blood Volume: 137 Page(s): 3604 - 3615
    07/01/2021 Authors: Gupta VA; Barwick BG; Matulis SM; Shirasaki R; Jaye DL; Keats JJ; Oberlton B; Joseph NS; Hofmeister CC; Heffner LT
  • Chromatin Accessibility Identifies Regulatory Elements Predictive of Gene Expression and Disease Outcome in Multiple Myeloma.
    Clin Cancer Res Volume: 27 Page(s): 3178 - 3189
    06/01/2021 Authors: Barwick BG; Gupta VA; Matulis SM; Patton JC; Powell DR; Gu Y; Jaye DL; Conneely KN; Lin YC; Hofmeister CC
  • The Murine MHC Class II Super Enhancer IA/IE-SE Contains a Functionally Redundant CTCF-Binding Component and a Novel Element Critical for Maximal Expression.
    J Immunol Volume: 206 Page(s): 2221 - 2232
    05/01/2021 Authors: Majumder P; Lee JT; Barwick BG; Patterson DG; Bally APR; Scharer CD; Boss JM
  • Ten-eleven translocation protein 1 modulates medulloblastoma progression.
    Genome Biol Volume: 22 Page(s): 125
    04/29/2021 Authors: Kim H; Kang Y; Li Y; Chen L; Lin L; Johnson ND; Zhu D; Robinson MH; McSwain L; Barwick BG
  • Oncolytic herpes simplex virus infects myeloma cells invitro and invivo.
    Mol Ther Oncolytics Volume: 20 Page(s): 519 - 531
    03/26/2021 Authors: Ghose J; Dona A; Murtadha M; Gunes EG; Caserta E; Yoo JY; Russell L; Jaime-Ramirez AC; Barwick BG; Gupta VA
  • Acetylation of KLF5 maintains EMT and tumorigenicity to cause chemoresistant bone metastasis in prostate cancer.
    Nat Commun Volume: 12 Page(s): 1714
    03/17/2021 Authors: Zhang B; Li Y; Wu Q; Xie L; Barwick B; Fu C; Li X; Wu D; Xia S; Chen J
  • YAP1 Expression in SCLC Defines a Distinct Subtype With T-cell-Inflamed Phenotype.
    J Thorac Oncol Volume: 16 Page(s): 464 - 476
    03/01/2021 Authors: Owonikoko TK; Dwivedi B; Chen Z; Zhang C; Barwick B; Ernani V; Zhang G; Gilbert-Ross M; Carlisle J; Khuri FR
  • Downregulation of PA28 induces proteasome remodeling and results in resistance to proteasome inhibitors in multiple myeloma.
    Blood Cancer J Volume: 10 Page(s): 125
    12/14/2020 Authors: Gu Y; Barwick BG; Shanmugam M; Hofmeister CC; Kaufman J; Nooka A; Gupta V; Dhodapkar M; Boise LH; Lonial S
  • We need CD38 STAT-JAK.
    Blood Volume: 136 Page(s): 2246 - 2248
    11/12/2020 Authors: Barwick BG; Lonial S
  • Epigenetically heterogeneous tumor cells direct collective invasion through filopodia-driven fibronectin micropatterning.
    Sci Adv Volume: 6 Page(s): eaaz6197
    07/01/2020 Authors: Summerbell ER; Mouw JK; Bell JSK; Knippler CM; Pedro B; Arnst JL; Khatib TO; Commander R; Barwick BG; Konen J
  • CD28 Regulates Metabolic Fitness for Long-Lived Plasma Cell Survival.
    Cell Rep Volume: 31 Page(s): 107815
    06/23/2020 Authors: Utley A; Chavel C; Lightman S; Holling GA; Cooper J; Peng P; Liu W; Barwick BG; Gavile CM; Maguire O
  • Electron transport chain activity is a predictor and target for venetoclax sensitivity in multiple myeloma.
    Nat Commun Volume: 11 Page(s): 1228
    03/06/2020 Authors: Bajpai R; Sharma A; Achreja A; Edgar CL; Wei C; Siddiqa AA; Gupta VA; Matulis SM; McBrayer SK; Mittal A
  • PD-1 Expression during Acute Infection Is Repressed through an LSD1-Blimp-1 Axis.
    J Immunol Volume: 204 Page(s): 449 - 458
    01/15/2020 Authors: Bally APR; Neeld DK; Lu P; Majumder P; Tang Y; Barwick BG; Wang Q; Boss JM
  • Gain of Chromosome 1q is associated with early progression in multiple myeloma patients treated with lenalidomide, bortezomib, and dexamethasone.
    Blood Cancer J Volume: 9 Page(s): 94
    11/25/2019 Authors: Schmidt TM; Barwick BG; Joseph N; Heffner LT; Hofmeister CC; Bernal L; Dhodapkar MV; Gupta VA; Jaye DL; Wu J
  • Multiple Myeloma Epigenetic Programming Prognostic of Outcome Converges with Loci Reprogrammed in Relapsed/Refractory Disease
    Volume: 134
    11/13/2019 Authors: Barwick BG; Skerget S; Keats JJ; Auclair D; Lonial S; Boise LH; Vertino PM; Powell DR
  • The Role of Proteasome Activator PA28 alpha in Multiple Myeloma
    Volume: 134
    11/13/2019 Authors: Gu Y; Barwick BG; Shanmugam M; Hofmeister CC; Kaufman JL; Nooka AK; Gupta VA; Dhodapkar MV; Boise LH; Lonial S
  • Integrated phosphoproteomics and transcriptional classifiers reveal hidden RAS signaling dynamics in multiple myeloma.
    Blood Adv Volume: 3 Page(s): 3214 - 3227
    11/12/2019 Authors: Lin Y-HT; Way GP; Barwick BG; Mariano MC; Marcoulis M; Ferguson ID; Driessen C; Boise LH; Greene CS; Wiita AP
  • Genetic heterogeneity within collective invasion packs drives leader and follower cell phenotypes.
    J Cell Sci Volume: 132
    10/09/2019 Authors: Zoeller EL; Pedro B; Konen J; Dwivedi B; Rupji M; Sundararaman N; Wang L; Horton JR; Zhong C; Barwick BG
  • DNA methylation reprogramming in relapsed/refractory myeloma converges with loci prognostic of survival in newly diagnosed patients
    Volume: 19 Page(s): E57 - E57
    10/01/2019 Authors: Barwick B; Skerget S; Keats J; Auclair D; Lonial S; Boise L; Vertino P
  • Antibody secreting cells require EZH2 for maximal metabolism, antibody production, and repression of the B cell transcriptional program
    Volume: 49 Page(s): 320 - 320
    10/01/2019 Authors: Guo M; Price MJ; Patterson DG; Barwick BG; Haines RR; Kania AK; Randall T; Boss JM; Scharer CD
  • Integrating Phosphoproteomics and Transcriptional Classifiers Reveals "Hidden Signaling" in Multiple Myeloma Including Differential KRAS and NRAS Mutant Effects
    Volume: 18 Page(s): S44 - S44
    08/13/2019 Authors: Lin Y-HT; Way GP; Barwick BG; Mariano MC; Marcoulis M; Ferguson ID; Driessen C; Boise LH; Greene CS; Wiita AP
  • Epigenetic programming underpins B cell dysfunction in human SLE.
    Nat Immunol Volume: 20 Page(s): 1071 - 1082
    08/01/2019 Authors: Scharer CD; Blalock EL; Mi T; Barwick BG; Jenks SA; Deguchi T; Cashman KS; Neary BE; Patterson DG; Hicks SL
  • Whole genome DNA methylation analysis of multiple myeloma identifies pervasive hypomethylation and biomarkers of survival
    Volume: 79
    07/01/2019 Authors: Barwick BG; Powell DR; Penaherrera D; Skerget S; Keats JJ; Auclair D; Lonial S; Boise LH; Vertino PM
  • PD-1 is negatively regulated by LSD1 through interactions with Blimp-1 during acute viral infection
    Volume: 202
    05/01/2019 Authors: Neeld DK; Bally A; Lu P; Majumder P; Barwick B; Boss JM
  • Epigenetic programming underpins B cell dysfunction in human SLE
    Volume: 202
    05/01/2019 Authors: Scharer C; Blalock E; Mi T; Barwick B; Jenks S; Neary B; Patterson D; Deguchi T; Lee E-H; Wei C
  • Multiple myeloma immunoglobulin lambda translocations portend poor prognosis.
    Nat Commun Volume: 10 Page(s): 1911
    04/23/2019 Authors: Barwick BG; Neri P; Bahlis NJ; Nooka AK; Dhodapkar MV; Jaye DL; Hofmeister CC; Kaufman JL; Gupta VA; Auclair D
  • Cell of Origin and Genetic Alterations in the Pathogenesis of Multiple Myeloma.
    Front Immunol Volume: 10 Page(s): 1121
    01/01/2019 Authors: Barwick BG; Gupta VA; Vertino PM; Boise LH
  • Immunoglobulin Lambda Translocations Identify Poor Outcome and IMiD Resistance in Multiple Myeloma and Co-Occur with Hyperdiploidy
    Volume: 132
    11/29/2018 Authors: Barwick BG; Neri P; Bahlis N; Nooka AK; Kaufman JL; Gupta VA; Auclair D; Keats JJ; Lonial S; Vertino PM
  • A Role for Syntenin-1 in Multiple Myeloma Cell Survival
    Volume: 132
    11/29/2018 Authors: Moser-Katz T; Gavile CM; Barwick BG; Lonial S; Boise LH
  • The Histone Demethylase LSD1 Regulates B Cell Proliferation and Plasmablast Differentiation.
    J Immunol Volume: 201 Page(s): 2799 - 2811
    11/01/2018 Authors: Haines RR; Barwick BG; Scharer CD; Majumder P; Randall TD; Boss JM
  • Syntenin regulates multiple myeloma cell survival
    Volume: 78
    07/01/2018 Authors: Moser-Katz T; Gavile CM; Barwick BG; Lonial S; Boise LH
  • B cell activation and plasma cell differentiation are inhibited by de novo DNA methylation.
    Nat Commun Volume: 9 Page(s): 1900
    05/15/2018 Authors: Barwick BG; Scharer CD; Martinez RJ; Price MJ; Wein AN; Haines RR; Bally APR; Kohlmeier JE; Boss JM
  • The histone demethylase LSD1 regulates B cell proliferation and plasmablast differentiation
    Volume: 200
    05/01/2018 Authors: Haines RR; Barwick BG; Majumder P; Scharer CD; Boss JM
  • LSD1 regulates PD-1 expression through interactions with Blimp-1 during acute viral infection
    Volume: 200
    05/01/2018 Authors: Neeld DK; Bally A; Majumder P; Barwick B; Boss JM
  • Galactic Cosmic Radiation Induces Persistent Epigenome Alterations Relevant to Human Lung Cancer.
    Sci Rep Volume: 8 Page(s): 6709
    04/30/2018 Authors: Kennedy EM; Powell DR; Li Z; Bell JSK; Barwick BG; Feng H; McCrary MR; Dwivedi B; Kowalski J; Dynan WS
  • Plasma cell differentiation is controlled by multiple cell division-coupled epigenetic programs.
    Nat Commun Volume: 9 Page(s): 1698
    04/27/2018 Authors: Scharer CD; Barwick BG; Guo M; Bally APR; Boss JM
  • 14-3-3 binds the proteasome, limits proteolytic function and enhances sensitivity to proteasome inhibitors.
    Leukemia Volume: 32 Page(s): 744 - 751
    03/01/2018 Authors: Gu Y; Xu K; Torre C; Samur M; Barwick BG; Rupji M; Arora J; Neri P; Kaufman J; Nooka A
  • EZH2 Represses the B Cell Transcriptional Program and Regulates Antibody-Secreting Cell Metabolism and Antibody Production.
    J Immunol Volume: 200 Page(s): 1039 - 1052
    02/01/2018 Authors: Guo M; Price MJ; Patterson DG; Barwick BG; Haines RR; Kania AK; Bradley JE; Randall TD; Boss JM; Scharer CD
  • High-Risk Myeloma Is Demarcated By Immunoglobulin Lambda Light Chain Translocations
    Volume: 130
    12/07/2017 Authors: Barwick B; Gupta VA; Auclair D; Keats JJ; Lonial S; Vertino PM; Boise LH
  • A B-Cell like Phenotype Is Associated with Sensitivity to Venetoclax in Multiple Myeloma
    Volume: 130
    12/07/2017 Authors: Gupta VA; Barwick B; Newman S; Keats JJ; Auclair D; Matulis S; Rossi MR; Nooka AK; Kaufman JL; Lonial S
  • CD86 regulates myeloma cell survival.
    Blood Adv Volume: 1 Page(s): 2307 - 2319
    11/28/2017 Authors: Gavile CM; Barwick BG; Newman S; Neri P; Nooka AK; Lonial S; Lee KP; Boise LH
  • LSD1 protects against hippocampal and cortical neurodegeneration.
    Nat Commun Volume: 8 Page(s): 805
    10/09/2017 Authors: Christopher MA; Myrick DA; Barwick BG; Engstrom AK; Porter-Stransky KA; Boss JM; Weinshenker D; Levey AI; Katz DJ
  • Oxidative phosphorylation is progressively programmed during plasma cell differentiation
    Volume: 198
    05/01/2017 Authors: Price MJ; Barwick BG; Scharer CD; Boss JM
  • Pathogenic epigenetic programming of expanded B cell subsets in systemic lupus erythematosus
    Volume: 198
    05/01/2017 Authors: Scharer C; Blalock E; Barwick BG; Gandham B; Neary B; Sanz I; Boss JM
  • MAX is an epigenetic sensor of 5-carboxylcytosine and is altered in multiple myeloma.
    Nucleic Acids Res Volume: 45 Page(s): 2396 - 2407
    03/17/2017 Authors: Wang D; Hashimoto H; Zhang X; Barwick BG; Lonial S; Boise LH; Vertino PM; Cheng X
  • Conserved Region C Functions To Regulate PD-1 Expression and Subsequent CD8 T Cell Memory.
    J Immunol Volume: 198 Page(s): 205 - 217
    01/01/2017 Authors: Bally APR; Tang Y; Lee JT; Barwick BG; Martinez R; Evavold BD; Boss JM
  • Plasma cell differentiation is coupled to division-dependent DNA hypomethylation and gene regulation.
    Nat Immunol Volume: 17 Page(s): 1216 - 1225
    10/01/2016 Authors: Barwick BG; Scharer CD; Bally APR; Boss JM
  • ATAC-seq on biobanked specimens defines a unique chromatin accessibility structure in nave SLE B cells.
    Sci Rep Volume: 6 Page(s): 27030
    06/01/2016 Authors: Scharer CD; Blalock EL; Barwick BG; Haines RR; Wei C; Sanz I; Boss JM
  • Epigenetic regulation of histone H3 lysine 27 (H3K27) controls the division-specific timing of gene expression during B cell differentiation
    Volume: 196
    05/01/2016 Authors: Scharer C; Barwick B; Bally A; Boss JM
  • Tissue-specific antigens induce dual complementary T cell tolerance mechanisms
    Volume: 196
    05/01/2016 Authors: Martinez RJ; Blanchfield L; Barwick B; Martinez H; Reid H; Evayold BD
  • Factors affecting the persistence of drug-induced reprogramming of the cancer methylome.
    Epigenetics Volume: 11 Page(s): 273 - 287
    04/02/2016 Authors: Bell JSK; Kagey JD; Barwick BG; Dwivedi B; McCabe MT; Kowalski J; Vertino PM
  • Genome-wide CIITA-binding profile identifies sequence preferences that dictate function versus recruitment.
    Nucleic Acids Res Volume: 43 Page(s): 3128 - 3142
    03/31/2015 Authors: Scharer CD; Choi NM; Barwick BG; Majumder P; Lohsen S; Boss JM
  • LSD1 continuously protects the differentiated state of neurons
    Volume: 26
    01/01/2015 Authors: Katz D; Christopher M; Myrick D; Engstrom A; Moudgal R; Barwick B; Levey A
  • Common distal elements orchestrate CIITA isoform-specific expression in multiple cell types.
    Genes Immun Volume: 15 Page(s): 543 - 555
    12/01/2014 Authors: Lohsen S; Majumder P; Scharer CD; Barwick BG; Austin JW; Zinzow-Kramer WM; Boss JM
  • Wnt signaling in triple negative breast cancer is associated with metastasis.
    BMC Cancer Volume: 13 Page(s): 537
    11/10/2013 Authors: Dey N; Barwick BG; Moreno CS; Ordanic-Kodani M; Chen Z; Oprea-Ilies G; Tang W; Catzavelos C; Kerstann KF; Sledge GW
  • Global DNA methylation remodeling accompanies CD8 T cell effector function.
    J Immunol Volume: 191 Page(s): 3419 - 3429
    09/15/2013 Authors: Scharer CD; Barwick BG; Youngblood BA; Ahmed R; Boss JM
  • Differential activation of Wnt--catenin pathway in triple negative breast cancer increases MMP7 in a PTEN dependent manner.
    PLoS One Volume: 8 Page(s): e77425
    01/01/2013 Authors: Dey N; Young B; Abramovitz M; Bouzyk M; Barwick B; De P; Leyland-Jones B
  • A heterozygous IDH1R132H/WT mutation induces genome-wide alterations in DNA methylation.
    Genome Res Volume: 22 Page(s): 2339 - 2355
    12/01/2012 Authors: Duncan CG; Barwick BG; Jin G; Rago C; Kapoor-Vazirani P; Powell DR; Chi J-T; Bigner DD; Vertino PM; Yan H
  • Age-associated DNA methylation in pediatric populations.
    Genome Res Volume: 22 Page(s): 623 - 632
    04/01/2012 Authors: Alisch RS; Barwick BG; Chopra P; Myrick LK; Satten GA; Conneely KN; Warren ST
  • Molecular characterisation of formalin-fixed paraffin-embedded (FFPE) breast tumour specimens using a custom 512-gene breast cancer bead array-based platform.
    Br J Cancer Volume: 105 Page(s): 1574 - 1581
    11/08/2011 Authors: Abramovitz M; Barwick BG; Willis S; Young B; Catzavelos C; Li Z; Kodani M; Tang W; Bouzyk M; Moreno CS
  • Heterozygosity for Pten promotes tumorigenesis in a mouse model of medulloblastoma.
    PLoS One Volume: 5 Page(s): e10849
    05/26/2010 Authors: Castellino RC; Barwick BG; Schniederjan M; Buss MC; Becher O; Hambardzumyan D; Macdonald TJ; Brat DJ; Durden DL
  • Prostate cancer genes associated with TMPRSS2-ERG gene fusion and prognostic of biochemical recurrence in multiple cohorts.
    Br J Cancer Volume: 102 Page(s): 570 - 576
    02/02/2010 Authors: Barwick BG; Abramovitz M; Kodani M; Moreno CS; Nam R; Tang W; Bouzyk M; Seth A; Leyland-Jones B
  • Wnt Signaling Prognosticates Outcome in Breast Cancer Cohorts.
    Volume: 69 Page(s): 509S - 509S
    12/15/2009 Authors: Barwick BG; Kerstann KF; Abramovitz M; Leyland-Jones BR
  • Identification of matrix metalloproteinase 7 (MMP7) as a selective biomarker of the triple-negative breast cancer subtype
    CANCER RESEARCH Volume: 69
    05/01/2009 Authors: Abramovitz M; Catzavelos C; Li Z; Kodani M; Barwick B; Tang W; Dey N; Moreno C; Bouzyk M; Leyland-Jones B
  • Cell line based model to study Wnt-beta catenin pathway in the control of tumor phenotypes in triple negative subset of breast cancer
    CANCER RESEARCH Volume: 69
    05/01/2009 Authors: Dey N; Kerstann K; De P; Barwick B; Marcus A; Moreno C; Abramovitz M; Bouzyk M; Leyland-Jones B
  • Protein-coding and MicroRNA Biomarker Gene Panels Predictive of Clinical Recurrence in Prostate Cancer
    FASEB JOURNAL Volume: 23
    04/01/2009 Authors: Moreno CS; Lai Y-H; Seth A; Osunkoya AO; Zhou W; Petros JA; Johnson BA; Nam RK; Barwick BG; Abramovitz M
  • DNA extraction from formalin-fixed, paraffin-embedded tissue.
    Cold Spring Harb Protoc Volume: 2009 Page(s): pdb.prot5138
    02/01/2009 Authors: Tang W; David FB; Wilson MM; Barwick BG; Leyland-Jones BR; Bouzyk MM
  • SF1126, A Novel PI3K Inhibitor Results in Downstream Inhibition of the PI3K Axis and Displays Sequen
    CLINICAL LYMPHOMA & MYELOMA Volume: 9 Page(s): S127 - S127
    02/01/2009 Authors: David E; Lonial S; Barwick B; Peng X; Kaufman J; Garlich J
  • Molecular differences in triple negative breast cancer between race/ethnicities.
    Volume: 69 Page(s): 183S - 183S
    01/15/2009 Authors: Bouzyk M; Barwick BG; Abramovitz M; Kodani M; Oprea G; Catzavelos C; Tang W; Moreno CS; Leyland-Jones B
  • Validation of a custom 512-gene breast cancer panel on the illumina-based DASL mRNA expression platform: focus on triple negative breast tumors using RNA from stored formalin-fixed, paraffin blocks.
    Volume: 69 Page(s): 164S - 164S
    01/15/2009 Authors: Abramovitz M; Calzavelos C; Li Z; Kodani M; Barwick B; Tang W; Moreno CS; Bouzyk M; Leyland-Jones B
  • Differential Wnt pathway activation in triple negative breast cancers comparative to HER2 and hormone positive breast cancers identified from formalin-fixed, paraffin-em bedded tissues
    Volume: 69 Page(s): 73S - 74S
    01/15/2009 Authors: Barwick BG; Abramovitz M; Tang W; Kodani M; Oprea GM; De PK; Catzavelos C; Bouzyk M; Moreno CS; Leyland-Jones B
  • Discovery of a novel set of prostate cancer-related genes associated with the prognostically important TMPRSS2:ERG fusion gene
    JOURNAL OF CLINICAL ONCOLOGY Volume: 26
    05/20/2008 Authors: Abramovitz M; Nam R; Kodani M; Barwick BG; Moreno C; Tang W; Bouzyk M; Seth A; Leyland-Jones B
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