Publications

• Suppressing recurrence in Sonic Hedgehog subgroup medulloblastoma using the OLIG2 inhibitor CT-179.
  Nat Commun Volume: 16 Page(s): 1091
  02/04/2025 Authors: Li Y; Lim C; Dismuke T; Malawsky DS; Oasa S; Bruce ZC; Offenhuser C; Baumgartner U; D'Souza RCJ; Edwards SL
• Chronic AMPK inactivation slows SHH medulloblastoma progression by inhibiting mTORC1 signaling and depleting tumor stem cells.
  iScience Volume: 26 Page(s): 108443
  12/15/2023 Authors: Malawsky DS; Dismuke T; Liu H; Castellino E; Brenman J; Dasgupta B; Tikunov A; Gershon TR
• Preventing recurrence in Sonic Hedgehog Subgroup Medulloblastoma using the OLIG2 inhibitor CT-179.
  Res Sq
  06/09/2023 Authors: Li Y; Lim C; Dismuke T; Malawsky DS; Oasa S; Bruce ZC; Offenhuser C; Baumgartner U; D'Souza RCJ; Edwards SL
• Whole-Body Mouse Fluxomic Analysis to Detect Metabolic Disruptions Associated with Microcephaly: Using 13C Isotopes.
  Methods Mol Biol Volume: 2583 Page(s): 149 - 156
  01/01/2023 Authors: Tikunov AP
• Green Chemistry Preservation and Extraction of Biospecimens for Multi-omic Analyses.
  Volume: 2394 Page(s): 267 - 298
  01/01/2022 Authors: Tikunov AP; Tipton JD; Garrett TJ; Shinde SV; Kim HJ; Gerber DA; Herring LE; Graves LM; Macdonald JM
• Poly(2-oxazoline) nanoparticle delivery enhances the therapeutic potential of vismodegib for medulloblastoma by improving CNS pharmacokinetics and reducing systemic toxicity.
  Nanomedicine Volume: 32 Page(s): 102345
  02/01/2021 Authors: Hwang D; Dismuke T; Tikunov A; Rosen EP; Kagel JR; Ramsey JD; Lim C; Zamboni W; Kabanov AV; Gershon TR
• Author Correction: Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer.
  Nat Med Volume: 26 Page(s): 982
  06/01/2020 Authors: Bryant KL; Stalnecker CA; Zeitouni D; Klomp JE; Peng S; Tikunov AP; Gunda V; Pierobon M; Waters AM; George SD
• Lyn regulates creatine uptake in an imatinib-resistant CML cell line.
  Biochim Biophys Acta Gen Subj Volume: 1864 Page(s): 129507
  04/01/2020 Authors: Okumu DO; Aponte-Collazo LJ; Dewar BJ; Cox NJ; East MP; Tech K; McDonald IM; Tikunov AP; Holmuhamedov E; Macdonald JM
• Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer.
  Nat Med Volume: 25 Page(s): 628 - 640
  04/01/2019 Authors: Bryant KL; Stalnecker CA; Zeitouni D; Klomp JE; Peng S; Tikunov AP; Gunda V; Pierobon M; Waters AM; George SD
• Beyond detoxification: Pleiotropic functions of multiple glutathione S-transferase isoforms protect mice against a toxic electrophile.
  PLoS One Volume: 14 Page(s): e0225449
  01/01/2019 Authors: Behrens KA; Jania LA; Snouwaert JN; Nguyen M; Moy SS; Tikunov AP; Macdonald JM; Koller BH
• Dose-response in a high density three-dimensional liver device with real-time bioenergetic and metabolic flux quantification.
  Toxicol In Vitro Volume: 45 Page(s): 119 - 127
  12/01/2017 Authors: Tikunov AP; Shim Y-S; Bhattarai N; Siler SQ; Soldatow V; LeCluyse EL; McDunn JE; Watkins PB; Macdonald JM
• Pyruvate Kinase Inhibits Proliferation during Postnatal Cerebellar Neurogenesis and Suppresses Medulloblastoma Formation.
  Cancer Res Volume: 77 Page(s): 3217 - 3230
  06/15/2017 Authors: Tech K; Tikunov AP; Farooq H; Morrissy AS; Meidinger J; Fish T; Green SC; Liu H; Li Y; Mungall AJ
• Buffered Versus Non-Buffered Lidocaine With Epinephrine for Mandibular Nerve Block: Clinical Outcomes.
  J Oral Maxillofac Surg Volume: 75 Page(s): 688 - 693
  04/01/2017 Authors: Phero JA; Nelson B; Davis B; Dunlop N; Phillips C; Reside G; Tikunov AP; White RP
• Advanced Liver Tissue Engineering Approaches and Their Measure of Success Using NMR/MRI
  Page(s): 273 - 310
  01/01/2017 Authors: Lee H; Jeffries RM; Tikunov AP; Macdonald JM
• p53 coordinates DNA repair with nucleotide synthesis by suppressing PFKFB3 expression and promoting the pentose phosphate pathway.
  Sci Rep Volume: 6 Page(s): 38067
  11/30/2016 Authors: Franklin DA; He Y; Leslie PL; Tikunov AP; Fenger N; Macdonald JM; Zhang Y
• Biocompatibility of Tygon tubing in microfluidic cell culture.
  Biomed Microdevices Volume: 17 Page(s): 20
  02/01/2015 Authors: Jiang X; Jeffries RE; Acosta MA; Tikunov AP; Macdonald JM; Walker GM; Gamcsik MP
• Ribosomal protein-Mdm2-p53 pathway coordinates nutrient stress with lipid metabolism by regulating MCD and promoting fatty acid oxidation.
  Proc Natl Acad Sci U S A Volume: 111 Page(s): E2414 - E2422
  06/10/2014 Authors: Liu Y; He Y; Jin A; Tikunov AP; Zhou L; Tollini LA; Leslie P; Kim T-H; Li LO; Coleman RA
• Fluxomics of the eastern oyster for environmental stress studies.
  Metabolites Volume: 4 Page(s): 53 - 70
  01/07/2014 Authors: Tikunov AP; Stoskopf MK; Macdonald JM
• Effect of oxygen concentration on viability and metabolism in a fluidized-bed bioartificial liver using P and C NMR spectroscopy.
  Tissue Eng Part C Methods Volume: 19 Page(s): 93 - 100
  02/01/2013 Authors: Jeffries RE; Gamcsik MP; Keshari KR; Pediaditakis P; Tikunov AP; Young GB; Lee H; Watkins PB; Macdonald JM
• Identification of metabolic pathways influenced by the G-protein coupled receptors GprB and GprD in Aspergillus nidulans.
  PLoS One Volume: 8 Page(s): e62088
  01/01/2013 Authors: de Souza WR; Morais ER; Krohn NG; Savoldi M; Goldman MHS; Rodrigues F; Caldana C; Semelka CT; Tikunov AP; Macdonald JM
• C magnetic resonance spectroscopy detection of changes in serine isotopomers reflects changes in mitochondrial redox status.
  Magn Reson Med Volume: 68 Page(s): 671 - 679
  09/01/2012 Authors: Johnson CB; Tikunov AP; Lee H; Wolak JE; Pediaditakis P; Romney DA; Holmuhamedov E; Gamcsik MP; Macdonald JM
• Application of Magnetic Resonance for Metabolomic Investigation of Mollusks
  Volume: 100 Page(s): 606 - 606
  02/02/2011 Authors: Tikunov AP; Lee H; Stoskopf MK; Macdonald JM
• Metabolomic investigations of American oysters using H-NMR spectroscopy.
  Mar Drugs Volume: 8 Page(s): 2578 - 2596
  10/08/2010 Authors: Tikunov AP; Johnson CB; Lee H; Stoskopf MK; Macdonald JM
• Applications of chemical shift imaging to marine sciences.
  Mar Drugs Volume: 8 Page(s): 2369 - 2383
  08/19/2010 Authors: Lee H; Tikunov A; Stoskopf MK; Macdonald JM
• Closure of VDAC causes oxidative stress and accelerates the Ca(2+)-induced mitochondrial permeability transition in rat liver mitochondria.
  Arch Biochem Biophys Volume: 495 Page(s): 174 - 181
  03/15/2010 Authors: Tikunov A; Johnson CB; Pediaditakis P; Markevich N; Macdonald JM; Lemasters JJ; Holmuhamedov E
• [The role of the voltage-dependent anion channels in the outer membrane of mitochondria in the regulation of cellular metabolism].
  Biofizika Volume: 55 Page(s): 822 - 833
  01/01/2010 Authors: Kholmukhamedov EL; Czerny C; Lovelace G; Beeson KC; Baker T; Johnson CB; Pediaditakis P; Teplova VV; Tikunov A; MacDonald J
• Minocycline and N-methyl-4-isoleucine cyclosporin (NIM811) mitigate storage/reperfusion injury after rat liver transplantation through suppression of the mitochondrial permeability transition.
  Hepatology Volume: 47 Page(s): 236 - 246
  01/01/2008 Authors: Theruvath TP; Zhong Z; Pediaditakis P; Ramshesh VK; Currin RT; Tikunov A; Holmuhamedov E; Lemasters JJ