Anna Kenney
- Department of Pediatrics
Associate Professor
-
Aflac Cancer and Blood Disorders Center
Pediatrics
1760 Haygood Drive
Academic Appointment
- Associate Professor of Pediatrics, Emory University
Education
Degrees
- PhD from Yale University
- BA from St. Mary’s College of Maryland
Research
Focus
- We investigate the mechanisms through which mitogenic signaling pathways in the developing brain can, through aberrant activity, contribute to the transformation of pediatric brain tumor cells-of-origin. Our goal is to identify signaling networks that could be targeted by small molecule inhibitors, to improve patient survival and quality of life.
Publications
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ZIC1 is a context-dependent medulloblastoma driver in the rhombic lip.
Nat Genet Volume: 57 Page(s): 88 - 102
01/01/2025 Authors: Lee JJY; Tao R; You Z; Haldipur P; Erickson AW; Farooq H; Hendriske LD; Abeysundara N; Richman CM; Wang EY -
Editor's Note: Inhibition of Phosphatidylinositol 3-Kinase Destabilizes Mycn Protein and Blocks Malignant Progression in Neuroblastoma.
Cancer Res Volume: 84 Page(s): 3311
10/01/2024 Authors: Chesler L; Schlieve C; Goldenberg DD; Kenney A; Kim G; McMillan A; Matthay KK; Rowitch D; Weiss WA -
HELZ promotes R loop resolution to facilitate DNA double-strand break repair by homologous recombination.
bioRxiv
12/15/2023 Authors: Haji-Seyed-Javadi R; Koyen AE; Rath SK; Madden MZ; Hou Y; Song BS; Kenney AM; Lan L; Yao B; Yu DS -
The LIN28B-let-7-PBK pathway is essential for group 3 medulloblastoma tumor growth and survival.
Mol Oncol Volume: 17 Page(s): 1784 - 1802
09/01/2023 Authors: Shahab SW; Roggeveen CM; Sun J; Kunhiraman H; McSwain LF; Juraschka K; Kumar SA; Saulnier O; Taylor MD; Schniederjan M -
Author Correction: YB1 modulates the DNA damage response in medulloblastoma.
Sci Rep Volume: 13 Page(s): 9717
06/15/2023 Authors: McSwain LF; Pillsbury CE; Haji-Seyed-Javadi R; Rath SK; Chen V; Huang T; Shahab SW; Kunhiraman H; Ross J; Price GA -
YB1 modulates the DNA damage response in medulloblastoma.
Sci Rep Volume: 13 Page(s): 8087
05/19/2023 Authors: McSwain LF; Pillsbury CE; Haji-Seyed-Javadi R; Rath SK; Chen V; Huang T; Shahab SW; Kunhiraman H; Ross J; Price GA -
IGFBP2 promotes proliferation and cell migration through STAT3 signaling in Sonic hedgehog medulloblastoma.
Acta Neuropathol Commun Volume: 11 Page(s): 62
04/08/2023 Authors: Kunhiraman H; McSwain L; Shahab SW; Gershon TR; MacDonald TJ; Kenney AM -
LIN28B-LET-7-PBK PATHWAY IS AN IMPORTANT REGULATOR OF GROUP 3 MEDULLOBLASTOMA PROLIFERATION
Volume: 24 Page(s): 46 - 46
11/01/2022 Authors: Shahab S; Sun J; Kunhiraman H; Schneiderjan M; Juraschka K; Kumar S; Taylor M; MacDonald T; Kenney A -
LOSS OF HISTONE H3 THREONINE 45 PHOSPHORYLATION DECREASES H3K36ME3 TO ABROGATE THE RADIATION-INDUCED DNA DAMAGE IN GLIOBLASTOMA MULTIFORME
Volume: 24 Page(s): 91 - 91
11/01/2022 Authors: Parwani K; Spangle J; McSwain L; Javadi RHS; Kenney A; Yu D -
SPATIOTEMPORAL GENOMICS OF HUMAN MEDULLOBLASTOMA WITHIN SUBGROUPS
Volume: 24 Page(s): 289 - 289
11/01/2022 Authors: Kunhiraman H; McSwain L; Shahab S; Kenney A