Anice Lowen
- Department of Microbiology and Immunology
Professor
-
Emory University
Microbiology and Immunology
1510 Clifton Rd -
Emory University School of Medicine
Microbiology and Immunology
1510 Clifton Rd., Room 3101 RRC
Overview
Dr. Lowen is a professor in the Department of Microbiology and Immunology at Emory University and Co-Principal Investigator of the Emory Center of Excellence for Influenza Research and Response (CEIRR). She received her BSc in Biochemistry from the University of Alberta and PhD in Virology from the University of Glasgow. Her post-doctoral training was with Dr. Peter Palese at Mount Sinai School of Medicine in New York City.
The Lowen lab exploits molecular tools, classical virology, and animal models of infection to study the biology of RNA viruses, including influenza A virus, mammalian orthoreovirus and SARS-CoV-2. We are particularly interested in features of their biology that shape evolutionary dynamics and in the respiratory transmission of influenza A virus and SARS-CoV-2.
Much of our prior and current work focuses on reassortment and recombination mechanisms by which co-infecting viruses exchange genetic information. In broader terms, we are interested in interactions among co-infecting viruses and the implications of these interactions for the evolution of viral populations. We also have active programs related to influenza A virus escape from humoral immunity, within-host viral diversity, influenza A virus emergence in new host species, viral detection by cytoplasmic dsRNA sensors and factors that determine the efficiency of SARS-CoV-2 transmission.
Academic Appointment
- Professor, Microbiology and Immunology, Emory University
Education
Degrees
- PhD from University of Glasgow
- BSc from University of Alberta
Research
Publications
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Pandemic risk stemming from the bovine H5N1 outbreak: an account of the knowns and unknowns.
J Virol Volume: 99 Page(s): e0005225
04/01/2025 Authors: Lowen AC; Baker AL; Bowman AS; Garca-Sastre A; Hensley SE; Lakdawala SS; Moncla LH; Nelson MI; Pekosz A; Poulson RL -
Dispersal of influenza virus populations within the respiratory tract shapes their evolutionary potential.
Proc Natl Acad Sci U S A Volume: 122 Page(s): e2419985122
01/01/2025 Authors: Ferreri LM; Seibert B; Caceres CJ; Patatanian K; Holmes KE; Gay LC; Cargnin Faccin F; Cardenas M; Carnaccini S; Shetty N -
The global H5N1 influenza panzootic in mammals.
Nature Volume: 637 Page(s): 304 - 313
01/01/2025 Authors: Peacock TP; Moncla L; Dudas G; VanInsberghe D; Sukhova K; Lloyd-Smith JO; Worobey M; Lowen AC; Nelson MI -
Influenza virus infection and aerosol shedding kinetics in a controlled human infection model.
J Virol Volume: 98 Page(s): e0161224
12/17/2024 Authors: Shetty N; Shephard MJ; Rockey NC; Macenczak H; Traenkner J; Danzy S; Vargas-Maldonado N; Arts PJ; Le Sage V; Anderson EJ -
Ventilation does not affect close-range transmission of influenza virus in a ferret playpen setup.
Proc Natl Acad Sci U S A Volume: 121 Page(s): e2322660121
08/13/2024 Authors: Rockey NC; Le Sage V; Shephard M; Vargas-Maldonado N; Vu MN; Brown CA; Patel K; French AJ; Merrbach GA; Walter S -
Murine modeling of menstruation identifies immune correlates of protection during Chlamydia muridarum challenge.
bioRxiv
05/23/2024 Authors: Lawrence LA; Vidal P; Varughese RS; Tiger Li Z-R; Chen TD; Tuske SC; Jimenez AR; Lowen AC; Shafer WM; Swaims-Kohlmeier A -
Risk assessment of a highly pathogenic H5N1 influenza virus from mink.
Nat Commun Volume: 15 Page(s): 4112
05/15/2024 Authors: Restori KH; Septer KM; Field CJ; Patel DR; VanInsberghe D; Raghunathan V; Lowen AC; Sutton TC -
Reply to Ebright et al., "Implementing governmental oversight of enhanced potential pandemic pathogen research".
J Virol Volume: 98 Page(s): e0025624
04/16/2024 Authors: Rasmussen AL; Gronvall G; Lowen AC; Goodrum F -
Reply to Lipsitch et al., "Public role in research oversight".
J Virol Volume: 98 Page(s): e0008424
04/16/2024 Authors: Rasmussen AL; Gronvall G; Lowen AC; Goodrum F -
Genetic drift and purifying selection shape within-host influenza A virus populations during natural swine infections.
PLoS Pathog Volume: 20 Page(s): e1012131
04/01/2024 Authors: VanInsberghe D; McBride DS; DaSilva J; Stark TJ; Lau MSY; Shepard SS; Barnes JR; Bowman AS; Lowen AC; Koelle K