Andrew Jenkins PhD
Overview
Dr. Jenkins is a tenured Associate Professor and Division Chief for Anesthesiology Research.
He has received numerous awards and fellowships, and serves on NIH study sections and the Editorial Boards of PLosOne and Molecular Pharmacology. He is a member of the Deans Faculty Development Advisory Committee and is an active teacher in Emorys graduate schools. A recognized leader in ion channel pharmacology, his work focuses on the molecular mechanisms of anesthesia and sleepiness.
Academic Appointment
- Associate Professor (with grant of Tenure), Dept. Anesthesiology, Emory University School of Medicine
- Assistant Professor (Joint Appointment), Dept. Pharmacology, Emory University School of Medicine
Education
Degrees
- PhD from Imperial College London & University of London
- B.Sc. (Hons.) from Physics Imperial College London & University of London
Research
Focus
- i. the molecular mechanisms of general anesthetics and synaptic inhibition ii. allosteric modulation of ion channel proteins iii. computational modeling of protein function iv. neuropharmacology of hypersomnia
Publications
-
De novo CLPTM1 variants with reduced GABAA R current response in patients with epilepsy.
Epilepsia Volume: 64 Page(s): 2968 - 2981
11/01/2023 Authors: Liu N; Li J; Gao K; Perszyk RE; Zhang J; Wang J; Wu Y; Jenkins A; Yuan H; Traynelis SF -
Screening Ion Channels in Cancer Cells.
J Vis Exp
06/16/2023 Authors: Kallay L; Gawali VS; Toukam DK; Bhattacharya D; Jenkins A; Sengupta S; Pomeranz Krummel DA -
Commonly Used Therapeutics Associated with Changes in Arousal Inhibit GABAAR Activation.
Biomolecules Volume: 13
02/15/2023 Authors: Kaplan A; Nash AI; Freeman AAH; Lewicki LG; Rye DB; Trotti LM; Brandt AL; Jenkins A -
Automated Intracellular Pharmacological Electrophysiology for Ligand-Gated Ionotropic Receptor and Pharmacology Screening.
Mol Pharmacol Volume: 100 Page(s): 73 - 82
07/01/2021 Authors: Perszyk RE; Yip MC; McConnell OL; Wang ET; Jenkins A; Traynelis SF; Forest CR -
Melanoma Cell Intrinsic GABAA Receptor Enhancement Potentiates Radiation and Immune Checkpoint Inhibitor Response by Promoting Direct and T Cell-Mediated Antitumor Activity.
Int J Radiat Oncol Biol Phys Volume: 109 Page(s): 1040 - 1053
03/15/2021 Authors: Pomeranz Krummel DA; Nasti TH; Kaluzova M; Kallay L; Bhattacharya D; Melms JC; Izar B; Xu M; Burnham A; Ahmed T -
RADIATION ENHANCES MELANOMA RESPONSE TO IMMUNOTHERAPY AND SYNERGIZES WITH BENZODIAZEPINES TO PROMOTE ANTI-TUMOR ACTIVITY
Volume: 21 Page(s): 84 - 84
11/01/2019 Authors: Krummel DP; Nasti T; Izar B; Xu M; Lowder L; Press R; Kaluzova M; Kallay L; Rupji M; Burnham A -
Modulating native GABAA receptors in medulloblastoma with positive allosteric benzodiazepine-derivatives induces cell death
Volume: 79
07/01/2019 Authors: Kallay L; Keskin H; Ross A; Rupji M; Moody OA; Wang X; Li G; Ahmed T; Rashid F; Stephen MR -
Antagonizing Na-K-Cl cotransporter NKCC1 impairs medulloblastoma cell viability
Volume: 79
07/01/2019 Authors: Burnhamm A; Kaluzova M; Kallay L; Li G; Ahmed T; Rashid F; Jenkins A; Cook J; Krummel DP; Sengupta S -
Reply: Novel GABRA2 variants in epileptic encephalopathy and intellectual disability with seizures.
Brain Volume: 142 Page(s): e16
05/01/2019 Authors: Jenkins A; Escayg A -
Modulating native GABAA receptors in medulloblastoma with positive allosteric benzodiazepine-derivatives induces cell death.
J Neurooncol Volume: 142 Page(s): 411 - 422
05/01/2019 Authors: Kallay L; Keskin H; Ross A; Rupji M; Moody OA; Wang X; Li G; Ahmed T; Rashid F; Stephen MR