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Profile

Ann Chahroudi MD, PhD

  • SOM: Peds: Infectious Disease
    Professor
  • (404) 727-9209
  • ann.m.chahroudi@emory.edu
Head shot of Ann Chahroudi

Academic Appointment

  • Professor of Pediatrics, Emory University School of Medicine

Education

Degrees

  • PhD from Emory University School of Medicine
  • MD from Emory University School of Medicine
  • BA from Brown University

Research

Focus

  • Viral pathogenesis and cure

    My research is centered on viral pathogenesis and treatment for HIV, Zika virus, and SARS-CoV-2. We aim to discover mechanisms of HIV persistence and test translational cure-directed strategies as well as uncover immunopathologies caused by Zika virus and SARS-CoV-2 infections using pediatric models and patient samples.

Publications

  • Divergent populations of HIV-infected naive and memory CD4+ T cell clones in children on antiretroviral therapy.
    J Clin Invest Volume: 135
    05/01/2025 Authors: Katusiime MG; Neer V; Guo S; Patro SC; Wang W; Luke B; Capoferri AA; Wu X; Horner AM; Rausch JW
  • Role of non-human primate models in accelerating research and developing countermeasures against Zika virus infection.
    Lancet Microbe Page(s): 101030
    02/20/2025 Authors: Li A; Coffey LL; Mohr EL; Raper J; Chahroudi A; Ausderau KK; Aliota MT; Friedrich TC; Mitzey AM; Koenig MR
  • SIV Env RhmAbs + N-803 at ART initiation prolongs viral decay without disrupting reservoir establishment in SIV-infected infant macaques.
    PLoS Pathog Volume: 21 Page(s): e1012863
    01/01/2025 Authors: Farinre O; Anaya T; King AC; Endrias K; Hbert AH; Hill AL; Jean S; Wood JS; Ehnert S; Liang S
  • Perinatal HIV: Past, Present, and Future.
    Clin Perinatol Volume: 51 Page(s): xix - xx
    12/01/2024 Authors: Violari A; Chahroudi A
  • A gut check: understanding the interplay of the gastrointestinal microbiome and the developing immune system towards the goal of pediatric HIV remission.
    Retrovirology Volume: 21 Page(s): 15
    10/18/2024 Authors: Soo N; Farinre O; Chahroudi A; Boliar S; Goswami R
  • Assessing the impact of autologous virus neutralizing antibodies on viral rebound time in postnatally SHIV-infected ART-treated infant rhesus macaques.
    Epidemics Volume: 48 Page(s): 100780
    09/01/2024 Authors: Mainou E; Berendam SJ; Obregon-Perko V; Uffman EA; Phan CT; Shaw GM; Bar KJ; Kumar MR; Fray EJ; Siliciano JM
  • Prevalence of detectable HIV-DNA and HIV-RNA in cerebrospinal fluid of youth with perinatal HIV and impaired cognition on antiretroviral therapy.
    AIDS Volume: 38 Page(s): 1494 - 1504
    08/01/2024 Authors: Wagner TA; Tierney C; Huang S; Nichols S; Malee KM; Montaez NA; Coletti A; Spiegel HML; Krotje C; Bone F
  • Pediatric immunotherapy and HIV control.
    Curr Opin HIV AIDS Volume: 19 Page(s): 201 - 211
    07/01/2024 Authors: Chinunga TT; Chahroudi A; Ribeiro SP
  • Assessing the impact of autologous neutralizing antibodies on rebound dynamics in postnatally SHIV-infected ART-treated infant rhesus macaques.
    bioRxiv
    06/03/2024 Authors: Mainou E; Berendam SJ; Obregon-Perko V; Uffman EA; Phan CT; Shaw GM; Bar KJ; Kumar MR; Fray EJ; Siliciano JM
  • Comparative analysis of within-host dynamics of acute infection and viral rebound dynamics in postnatally SHIV-infected ART-treated infant rhesus macaques.
    bioRxiv
    05/23/2024 Authors: Mainou E; Berendam SJ; Obregon-Perko V; Uffman EA; Phan CT; Shaw GM; Bar KJ; Kumar MR; Fray EJ; Siliciano JM
  • More than the Infinite Monkey Theorem: NHP Models in the Development of a Pediatric HIV Cure.
    Curr HIV/AIDS Rep Volume: 21 Page(s): 11 - 29
    02/01/2024 Authors: Fonseca JA; King AC; Chahroudi A
  • A novel HIV triple broadly neutralizing antibody (bNAb) combination-based passive immunization of infant rhesus macaques achieves durable protective plasma neutralization levels and mediates anti-viral effector functions.
    PLoS One Volume: 19 Page(s): e0312411
    01/01/2024 Authors: Dankwa S; Kosman C; Dennis M; Giorgi EE; Vuong K; Pahountis I; Garza A; Binuya C; McCarthy J; Mayer BT
  • Impact of the IL-15 superagonist N-803 on latency reversal induced by AZD5582 and on immune cells in ART-suppressed rhesus macaques
    Volume: 52 Page(s): 308 - 309
    10/01/2023 Authors: Dashti A; Sukkestad S; Horner AM; Neja M; Lin A; Schoof N; Singh V; Mavigner M; King H; Mason RD
  • Pilot study of a cIAP inhibitor ( AZD5582) + BCL-2 inhibitor (ABT199) in SIV-infected, art-suppressed rhesus macaques
    Volume: 52 Page(s): 333 - 333
    10/01/2023 Authors: Ukhueduan BO; Lopez LL; Bricker K; Schoof N; Singh V; Dashti A; Mavigner M; Schauer A; Tompkin L; Cottrell ML
  • AZD5582 plus SIV-specific antibodies reduce lymph node viral reservoirs in antiretroviral therapy-suppressed macaques.
    Nat Med Volume: 29 Page(s): 2535 - 2546
    10/01/2023 Authors: Dashti A; Sukkestad S; Horner AM; Neja M; Siddiqi Z; Waller C; Goldy J; Monroe D; Lin A; Schoof N
  • Assessing the impact of autologous neutralizing antibodies on viral rebound in postnatally SHIV-infected ART-treated infant rhesus macaques.
    bioRxiv
    09/14/2023 Authors: Mainou E; Berendam SJ; Obregon-Perko V; Uffman EA; Phan CT; Shaw GM; Bar KJ; Kumar MR; Fray EJ; Siliciano JM
  • Treatment with sofosbuvir attenuates the adverse neurodevelopmental consequences of Zika virus infection in infant rhesus macaques.
    J Neuroimmunol Volume: 381 Page(s): 578148
    08/15/2023 Authors: Medina A; Rusnak R; Richardson R; Zimmerman MG; Suthar M; Schoof N; Kovacs-Balint Z; Mavigner M; Sanchez M; Chahroudi A
  • Anti-SIV Env RhmAbs +/-CD8a depletion and N-803 in ART-suppressed rhesus macaques leads to post-treatment control of viremia in a subset of animals
    Volume: 26
    08/01/2023 Authors: Singh V; Burgess D; Dashti A; McBrien J; King H; Mason R; Safrit J; Lifson J; Tuyishime M; Ferrari G
  • Broadly neutralizing antibodies: "The next thing" to treat children with HIV?
    Sci Transl Med Volume: 15 Page(s): eadi0293
    07/05/2023 Authors: Mavigner M; Chahroudi A
  • Nucleic acid biomarkers of immune response and cell and tissue damage in children with COVID-19 and MIS-C.
    Cell Rep Med Volume: 4 Page(s): 101034
    06/20/2023 Authors: Loy CJ; Sotomayor-Gonzalez A; Servellita V; Nguyen J; Lenz J; Bhattacharya S; Williams ME; Cheng AP; Bliss A; Saldhi P
  • Brain microglia serve as a persistent HIV reservoir despite durable antiretroviral therapy.
    J Clin Invest Volume: 133
    06/15/2023 Authors: Tang Y; Chaillon A; Gianella S; Wong LM; Li D; Simermeyer TL; Porrachia M; Ignacio C; Woodworth B; Zhong D
  • Serologic responses to COVID-19 vaccination in children with history of multisystem inflammatory syndrome (MIS-C).
    Vaccine Volume: 41 Page(s): 2743 - 2748
    04/24/2023 Authors: Perez MA; Hsiao H-M; Chen X; Kunkel A; Baida N; Hussaini L; Lu AT; Kao CM; Laham FR; Hunstad DA
  • Multiplatform analyses reveal distinct drivers of systemic pathogenesis in adult versus pediatric severe acute COVID-19.
    Nat Commun Volume: 14 Page(s): 1638
    04/04/2023 Authors: Druzak S; Iffrig E; Roberts BR; Zhang T; Fibben KS; Sakurai Y; Verkerke HP; Rostad CA; Chahroudi A; Schneider F
  • How CD4+ T Cells Transcriptional Profile Is Affected by Culture Conditions: Towards the Design of Optimal In Vitro HIV Reactivation Assays.
    Biomedicines Volume: 11
    03/13/2023 Authors: Pascucci GR; Morrocchi E; Pighi C; Rotili A; Neri A; Medri C; Olivieri G; Sanna M; Rasi G; Persaud D
  • Highlights from the Tenth International Workshop on HIV Persistence during Therapy, December 13-16, 2022, Miami, Florida-USA.
    J Virus Erad Volume: 9 Page(s): 100315
    03/01/2023 Authors: Archin N; Bar KJ; Burdo T; Caskey M; Chahroudi A; Farzan M; Ho Y-C; Jones RB; Kearney M; Kuritzkes D
  • CD8+ lymphocytes do not impact SIV reservoir establishment under ART.
    Nat Microbiol Volume: 8 Page(s): 299 - 308
    02/01/2023 Authors: Statzu M; Jin W; Fray EJ; Wong AKH; Kumar MR; Ferrer E; Docken SS; Pinkevych M; McBrien JB; Fennessey CM
  • A simple model for viral decay dynamics and the distribution of infected cell life spans in SHIV-infected infant rhesus macaques.
    Math Biosci Volume: 356 Page(s): 108958
    02/01/2023 Authors: Sass J; Awasthi A; Obregon-Perko V; McCarthy J; Lloyd AL; Chahroudi A; Permar S; Chan C
  • Genetic variations in the envelope of SHIV-infected ART-treated infant macaques rebound viruses that escape neutralization by autologous antibodies
    Volume: 51 Page(s): 301 - 301
    10/01/2022 Authors: Berendam S; Uffman E; Kumar A; Obregon-Perko V; Styles T; Bar K; Shaw G; Silvestri G; Amara R; Chahroudi A
  • Comparison of Mid-turbinate Nasal Swabs, Saliva, and Nasopharyngeal Swabs for SARS-CoV-2 Reverse Transcription-Polymerase Chain Reaction Testing in Pediatric Outpatients.
    Arch Pathol Lab Med Volume: 146 Page(s): 1056 - 1061
    09/01/2022 Authors: Vos MB; Gonzalez MD; Stone C; Cleeton R; Figueroa J; Jerris R; Park SI; Heilman S; Nayee R; Chahroudi A
  • SARS-CoV-2 Infection and Racial Disparities in Children: Protective Mechanisms and Severe Complications Related to MIS-C.
    J Racial Ethn Health Disparities Volume: 9 Page(s): 1536 - 1542
    08/01/2022 Authors: Kurup S; Burgess R; Tine F; Chahroudi A; Lee DL
  • High prevalence of HIV persistence in CSF of adolescents and young adults with perinatally-acquired HIV and cognitive impairment in the IMPAACT 2015 study
    Volume: 25 Page(s): 115 - 116
    08/01/2022 Authors: Wagner T; Tierney C; Huang S; Nichols S; Malee K; Montanez N; Coletti A; Spiegel H; Wilkins M; Abuogi L
  • AZD5582 and SIV Env-targeting rhesus monoclonal antibodies (RhmAbs) +/- N-803 in SIV-infected ART-suppressed rhesus macaques
    Volume: 25 Page(s): 7 - 7
    08/01/2022 Authors: Dashti A; Sukkestad S; Horner AM; Neja M; Lin A; Schoof N; Mavigner M; Lifson JD; Falcinelli SD; Sacha J
  • CD8 depletion and N-803 plus anti-SIV Env RhmAbs in ART-suppressed rhesus macaques
    Volume: 25 Page(s): 237 - 237
    08/01/2022 Authors: Singh V; Burgess D; Dashti A; McBrien J; King H; Mason R; Safrit J; Lifson J; Tuyishime M; Ferrari G
  • Altered Response Pattern following AZD5582 Treatment of SIV-Infected, ART-Suppressed Rhesus Macaque Infants.
    J Virol Volume: 96 Page(s): e0169921
    04/13/2022 Authors: Bricker KM; Obregon-Perko V; Williams B; Oliver D; Uddin F; Neja M; Hopkins L; Dashti A; Jean S; Wood JS
  • Support for Establishing Best Practices for Breastfeeding in the Current HIV/ART Era.
    J Pediatric Infect Dis Soc Volume: 11 Page(s): 90 - 91
    03/24/2022 Authors: Cranmer LM; Chung MH; Chahroudi A
  • Serologic and Cytokine Signatures in Children With Multisystem Inflammatory Syndrome and Coronavirus Disease 2019.
    Open Forum Infect Dis Volume: 9 Page(s): ofac070
    03/01/2022 Authors: Lapp SA; Abrams J; Lu AT; Hussaini L; Kao CM; Hunstad DA; Rosenberg RB; Zafferani MJ; Ede KC; Ballan W
  • Limited induction of SARS-CoV-2-specific T cell responses in children with multisystem inflammatory syndrome compared with COVID-19.
    JCI Insight Volume: 7
    02/22/2022 Authors: Singh V; Obregon-Perko V; Lapp SA; Horner AM; Brooks A; Macoy L; Hussaini L; Lu A; Gibson T; Silvestri G
  • HIV Reservoirs: Modeling, Quantification, and Approaches to a Cure.
    Methods Mol Biol Volume: 2407 Page(s): 215 - 228
    01/01/2022 Authors: Dashti A; Singh V; Chahroudi A
  • Correction to: Designing Cure Studies in NHPs.
    Methods Mol Biol Volume: 2407 Page(s): C1
    01/01/2022 Authors: Dashti A; Singh V; Chahroudi A
  • Challenges and Opportunities of Therapies Targeting Early Life Immunity for Pediatric HIV Cure.
    Front Immunol Volume: 13 Page(s): 885272
    01/01/2022 Authors: Berendam SJ; Nelson AN; Yagnik B; Goswami R; Styles TM; Neja MA; Phan CT; Dankwa S; Byrd AU; Garrido C
  • The rectal mucosal immune environment and HIV susceptibility among young men who have sex with men.
    Front Immunol Volume: 13 Page(s): 972170
    01/01/2022 Authors: Ackerley CG; Smith SA; Murray PM; Amancha PK; Arthur RA; Zhu Z; Chahroudi A; Amara RR; Hu Y-J; Kelley CF
  • Dynamics and origin of rebound viremia in SHIV-infected infant macaques following interruption of long-term ART.
    JCI Insight Volume: 6
    12/08/2021 Authors: Obregon-Perko V; Bricker KM; Mensah G; Uddin F; Rotolo L; Vanover D; Desai Y; Santangelo PJ; Jean S; Wood JS
  • Research priorities for an HIV cure: International AIDS Society Global Scientific Strategy 2021.
    Nat Med Volume: 27 Page(s): 2085 - 2098
    12/01/2021 Authors: Deeks SG; Archin N; Cannon P; Collins S; Jones RB; de Jong MAWP; Lambotte O; Lamplough R; Ndung'u T; Sugarman J
  • Secretory phospholipase A2 in SARS-CoV-2 infection and multisystem inflammatory syndrome in children (MIS-C).
    Exp Biol Med (Maywood) Volume: 246 Page(s): 2543 - 2552
    12/01/2021 Authors: Kuypers FA; Rostad CA; Anderson EJ; Chahroudi A; Jaggi P; Wrammert J; Mantus G; Basu R; Harris F; Hanberry B
  • Single-Amplicon Multiplex Real-Time Reverse Transcription-PCR with Tiled Probes To Detect SARS-CoV-2 spike Mutations Associated with Variants of Concern.
    J Clin Microbiol Volume: 59 Page(s): e0144621
    11/18/2021 Authors: Babiker A; Immergluck K; Stampfer SD; Rao A; Bassit L; Su M; Nguyen V; Stittleburg V; Ingersoll JM; Bradley HL
  • SARS-CoV-2 immune repertoire in MIS-C and pediatric COVID-19.
    Nat Immunol Volume: 22 Page(s): 1452 - 1464
    11/01/2021 Authors: Ravichandran S; Tang J; Grubbs G; Lee Y; Pourhashemi S; Hussaini L; Lapp SA; Jerris RC; Singh V; Chahroudi A
  • The need for new test verification and regulatory support for innovative diagnostics.
    Nat Biotechnol Volume: 39 Page(s): 1060 - 1062
    09/01/2021 Authors: Roback JD; Tyburski EA; Alter D; Asakrah S; Chahroudi A; Esper A; Farmer S; Figueroa J; K Frediani J; D Gonzalez M
  • New Latency Reversing Agents for HIV-1 Cure: Insights from Nonhuman Primate Models.
    Viruses Volume: 13
    08/06/2021 Authors: Bricker KM; Chahroudi A; Mavigner M
  • Multidisciplinary assessment of the Abbott BinaxNOW SARS-CoV-2 point-of-care antigen test in the context of emerging viral variants and self-administration.
    Sci Rep Volume: 11 Page(s): 14604
    07/16/2021 Authors: Frediani JK; Levy JM; Rao A; Bassit L; Figueroa J; Vos MB; Wood A; Jerris R; Van Leung-Pineda; Gonzalez MD
  • Altered amino acid profile in patients with SARS-CoV-2 infection.
    Proc Natl Acad Sci U S A Volume: 118
    06/22/2021 Authors: Rees CA; Rostad CA; Mantus G; Anderson EJ; Chahroudi A; Jaggi P; Wrammert J; Ochoa JB; Ochoa A; Basu RK
  • RIFAXIMIN TO PREVENT BLOODSTREAM INFECTIONS IN PEDIATRIC HEMATOPOIETIC CELL TRANSPLANTATION (HCT)
    Volume: 68 Page(s): S105 - S105
    06/01/2021 Authors: Teherani M; Gillespie S; Pratte Z; Banksota S; Gulick D; Djeddar N; Chahroudi A; Horan J; Gibson G; Qayed M
  • Will We Have the Tools to Address a Reemergent Zika Virus Epidemic?
    Ann Intern Med Volume: 174 Page(s): 708 - 709
    05/01/2021 Authors: Chahroudi A; Permar S
  • Rapid progression is associated with lymphoid follicle dysfunction in SIV-infected infant rhesus macaques.
    PLoS Pathog Volume: 17 Page(s): e1009575
    05/01/2021 Authors: Wood MP; Jones CI; Lippy A; Oliver BG; Walund B; Fancher KA; Fisher BS; Wright PJ; Fuller JT; Murapa P
  • The RADx Tech Test Verification Core and the ACME POCT in the Evaluation of COVID-19 Testing Devices: A Model for Progress and Change.
    IEEE Open J Eng Med Biol Volume: 2 Page(s): 142 - 151
    04/28/2021 Authors: Nehl E; Heilman S; Ku D; Gottfried D; Farmer S; Mannino R; Tyburski E; Sullivan J; Suessmith A; Bassit L
  • Latency Reversal 2.0: Giving the Immune System a Seat at the Table.
    Curr HIV/AIDS Rep Volume: 18 Page(s): 117 - 127
    04/01/2021 Authors: Singh V; Dashti A; Mavigner M; Chahroudi A
  • CD8 lymphocyte depletion enhances the latency reversal activity of the SMAC mimetic AZD5582 in ART-suppressed SIV-infected rhesus macaques.
    J Virol Volume: 95
    03/25/2021 Authors: Mavigner M; Liao LE; Brooks AD; Ke R; Mattingly C; Schoof N; McBrien J; Carnathan D; Liang S; Vanderford TH
  • Covid-19 will not "magically disappear": Why access to widespread testing is paramount.
    Am J Hematol Volume: 96 Page(s): 174 - 178
    02/01/2021 Authors: George PE; Stokes CL; Bassit LC; Chahroudi A; Figueroa J; Griffiths MA; Heilman S; Ku DN; Nehl EJ; Leong T
  • Systematic Assessment of Antiviral Potency, Breadth, and Synergy of Triple Broadly Neutralizing Antibody Combinations against Simian-Human Immunodeficiency Viruses.
    J Virol Volume: 95
    01/13/2021 Authors: Berendam SJ; Styles TM; Morgan-Asiedu PK; Tenney D; Kumar A; Obregon-Perko V; Bar KJ; Saunders KO; Santra S; De Paris K
  • Clinical and Preclinical Evidence for Adverse Neurodevelopment after Postnatal Zika Virus Infection.
    Trop Med Infect Dis Volume: 6
    01/12/2021 Authors: Raper J; Chahroudi A
  • Non-human Primate Models to Investigate Mechanisms of Infection-Associated Fetal and Pediatric Injury, Teratogenesis and Stillbirth.
    Front Genet Volume: 12 Page(s): 680342
    01/01/2021 Authors: Li M; Brokaw A; Furuta AM; Coler B; Obregon-Perko V; Chahroudi A; Wang H-Y; Permar SR; Hotchkiss CE; Golos TG
  • Elimination of SHIV Infected Cells by Combinations of Bispecific HIVxCD3 DART Molecules.
    Front Immunol Volume: 12 Page(s): 710273
    01/01/2021 Authors: Tuyishime M; Dashti A; Faircloth K; Jha S; Nordstrom JL; Haynes BF; Silvestri G; Chahroudi A; Margolis DM; Ferrari G
  • Understanding Viral and Immune Interplay During Vertical Transmission of HIV: Implications for Cure.
    Front Immunol Volume: 12 Page(s): 757400
    01/01/2021 Authors: Amin O; Powers J; Bricker KM; Chahroudi A
  • Original antigenic sin responses to Betacoronavirus spike proteins are observed in a mouse model, but are not apparent in children following SARS-CoV-2 infection.
    PLoS One Volume: 16 Page(s): e0256482
    01/01/2021 Authors: Lapp SA; Edara VV; Lu A; Lai L; Hussaini L; Chahroudi A; Anderson LJ; Suthar MS; Anderson EJ; Rostad CA
  • Simian-Human Immunodeficiency Virus SHIV.C.CH505 Persistence in ART-Suppressed Infant Macaques Is Characterized by Elevated SHIV RNA in the Gut and a High Abundance of Intact SHIV DNA in Naive CD4+ T Cells.
    J Virol Volume: 95
    12/22/2020 Authors: Obregon-Perko V; Bricker KM; Mensah G; Uddin F; Kumar MR; Fray EJ; Siliciano RF; Schoof N; Horner A; Mavigner M
  • Quantitative SARS-CoV-2 Serology in Children With Multisystem Inflammatory Syndrome (MIS-C).
    Pediatrics Volume: 146
    12/01/2020 Authors: Rostad CA; Chahroudi A; Mantus G; Lapp SA; Teherani M; Macoy L; Tarquinio KM; Basu RK; Kao C; Linam WM
  • SMAC Mimetic Plus Triple-Combination Bispecific HIVxCD3 Retargeting Molecules in SHIV.C.CH505-Infected, Antiretroviral Therapy-Suppressed Rhesus Macaques.
    Volume: 94
    10/14/2020 Authors: Dashti A; Waller C; Mavigner M; Schoof N; Bar KJ; Shaw GM; Vanderford TH; Liang S; Lifson JD; Dunham RM
  • Therapeutic vaccination of SIV-infected, ART-treated infant rhesus macaques using Ad48/MVA in combination with TLR-7 stimulation.
    PLoS Pathog Volume: 16 Page(s): e1008954
    10/01/2020 Authors: Bricker KM; Obregon-Perko V; Uddin F; Williams B; Uffman EA; Garrido C; Fouda GG; Geleziunas R; Robb M; Michael N
  • Therapeutic vaccination induces antiviral T-cell response in SIV-infected ART-treated infant macaques
    Volume: 49 Page(s): 248 - 248
    10/01/2020 Authors: Bricker K; Obregon-Perko V; Uddin F; Hesselgesser J; Robb M; Michael N; Barouch D; Chahroudi A
  • Rapid progression in SIV-infected infant rhesus macaques is associated with failure to increase CXCL13 during acute infection, B-cell dysfunction and early viral replication
    Volume: 49 Page(s): 227 - 228
    10/01/2020 Authors: Wood M; Jones CI; Fisher B; Lippy A; Oliver BG; Walund B; Fancher K; Murapa P; Fuller JT; Habib J
  • Development of a polyfunctional antiviral broadly neutralizing antibody combination for passive immunization of in Simian Human Immunodeficiency Virus (SHIV)-infected infant Rhesus macaques
    Volume: 49 Page(s): 246 - 247
    10/01/2020 Authors: Berendam SJ; Styles TM; Morgan-Asiedu PK; Bar KJ; Shaw GM; Saunders KO; DeParis K; Chahroudi A; Permar SR; Amara RR
  • Viral & immune dynamics in an NHP model of pediatric HIV infection: studies to inform cure strategies
    Volume: 49 Page(s): 236 - 236
    10/01/2020 Authors: Obregon-Perko V; Bricker K; Uddin F; Berendam S; Fouda G; Bar K; Shaw G; Silvestri G; Permar S; Chahroudi A
  • Combination of CD8 Depletion and Interleukin-15 Superagonist N-803 Induces Virus Reactivation in Simian-Human Immunodeficiency Virus-Infected, Long-Term ART-Treated Rhesus Macaques.
    J Virol Volume: 94
    09/15/2020 Authors: McBrien JB; Wong AKH; White E; Carnathan DG; Lee JH; Safrit JT; Vanderford TH; Paiardini M; Chahroudi A; Silvestri G
  • Innate, non-cytolytic CD8+ T cell-mediated suppression of HIV replication by MHC-independent inhibition of virus transcription.
    PLoS Pathog Volume: 16 Page(s): e1008821
    09/01/2020 Authors: Zanoni M; Palesch D; Pinacchio C; Statzu M; Tharp GK; Paiardini M; Chahroudi A; Bosinger SE; Yoon J; Cox B
  • The Brain Retains: Nonhuman Primate Models for Pediatric HIV-1 in the CNS.
    Curr HIV/AIDS Rep Volume: 17 Page(s): 343 - 353
    08/01/2020 Authors: Obregon-Perko V; Bricker K; Chahroudi A
  • The VACCINES Act: Deciphering Vaccine Hesitancy in the Time of COVID-19.
    Clin Infect Dis Volume: 71 Page(s): 703 - 705
    07/28/2020 Authors: McAteer J; Yildirim I; Chahroudi A
  • Safety, Tolerability, and Pharmacokinetics of the Broadly Neutralizing Human Immunodeficiency Virus (HIV)-1 Monoclonal Antibody VRC01 in HIV-Exposed Newborn Infants.
    J Infect Dis Volume: 222 Page(s): 628 - 636
    07/23/2020 Authors: Cunningham CK; McFarland EJ; Morrison RL; Capparelli EV; Safrit JT; Mofenson LM; Mathieson B; Valentine ME; Perlowski C; Smith B
  • Pediatric HIV: the Potential of Immune Therapeutics to Achieve Viral Remission and Functional Cure.
    Curr HIV/AIDS Rep Volume: 17 Page(s): 237 - 248
    06/01/2020 Authors: Berendam SJ; Nelson AN; Goswami R; Persaud D; Haigwood NL; Chahroudi A; Fouda GG; Permar SR
  • Long-term alterations in brain and behavior after postnatal Zika virus infection in infant macaques.
    Nat Commun Volume: 11 Page(s): 2534
    05/21/2020 Authors: Raper J; Kovacs-Balint Z; Mavigner M; Gumber S; Burke MW; Habib J; Mattingly C; Fair D; Earl E; Feczko E
  • Therapeutic vaccination with Ad48/MVA and TLR7 stimulation in SIV-infected, ART-treated infant rhesus macaques
    Volume: 204
    05/01/2020 Authors: Bricker KM; Obregon-Perko V; Uddin F; Williams B; Hesselgesser J; Robb M; Michael N; Barouch DH; Chahroudi A
  • Correction for Mavigner et al., "Simian Immunodeficiency Virus Persistence in Cellular and Anatomic Reservoirs in Antiretroviral Therapy-Suppressed Infant Rhesus Macaques".
    J Virol Volume: 94
    03/31/2020 Authors: Mavigner M; Habib J; Deleage C; Rosen E; Mattingly C; Bricker K; Kashuba A; Amblard F; Schinazi RF; Lawson B
  • Author Correction: Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells.
    Nature Volume: 578 Page(s): E21
    02/01/2020 Authors: McBrien JB; Mavigner M; Franchitti L; Smith SA; White E; Tharp GK; Walum H; Busman-Sahay K; Aguilera-Sandoval CR; Thayer WO
  • Systemic HIV and SIV latency reversal via non-canonical NF-B signalling in vivo.
    Nature Volume: 578 Page(s): 160 - 165
    02/01/2020 Authors: Nixon CC; Mavigner M; Sampey GC; Brooks AD; Spagnuolo RA; Irlbeck DM; Mattingly C; Ho PT; Schoof N; Cammon CG
  • Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells.
    Nature Volume: 578 Page(s): 154 - 159
    02/01/2020 Authors: McBrien JB; Mavigner M; Franchitti L; Smith SA; White E; Tharp GK; Walum H; Busman-Sahay K; Aguilera-Sandoval CR; Thayer WO
  • Upward Trends of Parotitis and Mumps in Atlanta over a Decade.
    Glob Pediatr Health Volume: 7 Page(s): 2333794X20968676
    01/01/2020 Authors: Reddy LM; Bloch D; Mallino A; Kumari P; Figueroa J; Kendrick L; Chahroudi A; Tuttle J; Thomas E; Morris CR
  • Pharmacological Modulation of the Wnt/-Catenin Pathway Inhibits Proliferation and Promotes Differentiation of Long-Lived Memory CD4+ T Cells in Antiretroviral Therapy-Suppressed Simian Immunodeficiency Virus-Infected Macaques.
    J Virol Volume: 94
    12/12/2019 Authors: Mavigner M; Zanoni M; Tharp GK; Habib J; Mattingly CR; Lichterfeld M; Nega MT; Vanderford TH; Bosinger SE; Chahroudi A
  • An NHP model of pediatric oral HIV infection and ART treatment
    Volume: 48 Page(s): 285 - 285
    10/01/2019 Authors: Obregon-Perko V; Bricker K; Fouda G; Bar K; Shaw G; Silvestri G; Permar S; Chahroudi A
  • Immunological effects of the IL-15 superagonist N-803 in SIV-infected ART-treated rhesus macaques
    Volume: 48 Page(s): 307 - 308
    10/01/2019 Authors: McBrien J; White E; Tharp G; Jeng E; Wong H; Safrit J; Paiardini M; Vanderford T; Lifson J; Bosinger S
  • Postnatal Zika virus infection causes persistent abnormalities in brain structure, function, and behavior in infant macaques: one year follow-up study
    Volume: 48 Page(s): 277 - 277
    10/01/2019 Authors: Mavigner M; Raper J; Kovacs-Balint Z; Gumber S; Sanchez M; Alvarado M; Chahroudi A
  • Similar frequency of infection of naive and memory CD4(+) T-cells in ART-suppressed SIV/SHIV-infected infant rhesus macaques
    Volume: 48 Page(s): 292 - 293
    10/01/2019 Authors: Mattingly C; Goswami R; Nelson A; Schoof N; Shaw G; Bar K; Mavigner M; Van Rompay K; Permar S; Chahroudi A
  • Analytical Treatment Interruption after Short-Term Antiretroviral Therapy in a Postnatally Simian-Human Immunodeficiency Virus-Infected Infant Rhesus Macaque Model.
    mBio Volume: 10
    09/05/2019 Authors: Goswami R; Nelson AN; Tu JJ; Dennis M; Feng L; Kumar A; Mangold J; Mangan RJ; Mattingly C; Curtis AD
  • Oral TLR7 agonist administration induces an immunostimulatory response in SIV-infected ART-suppressed infant Rhesus macaques
    Volume: 22 Page(s): 40 - 40
    07/01/2019 Authors: Bricker K; Obregon-Perko V; Hesselgesser J; Chahroudi A
  • Sting agonist as a kick and kill agent to target the HIV reservoir
    Volume: 22 Page(s): 42 - 42
    07/01/2019 Authors: Mavigner M; Brooks AD; Koblansky A; Galardi C; Madsen H; Margolis DM; Silvestri G; Chahroudi A
  • Improved Perinatal and Postpartum Human Immunodeficiency Virus Outcomes After Use of a Perinatal Care Coordination Team.
    Open Forum Infect Dis Volume: 6 Page(s): ofz183
    06/01/2019 Authors: Hackett S; Badell ML; Meade CM; Davis JM; Blue J; Curtin L; Camacho-Gonzalez A; Chahroudi A; Chakraborty R; Nguyen MLT
  • Poverty and chronic illness: why safety net programs matter.
    Pediatr Res Volume: 85 Page(s): 743 - 744
    05/01/2019 Authors: Bloch D; Chahroudi A
  • Correction for Mavigner et al., "Simian Immunodeficiency Virus Persistence in Cellular and Anatomic Reservoirs in Antiretroviral Therapy-Suppressed Infant Rhesus Macaques".
    J Virol Volume: 93
    02/01/2019 Authors: Mavigner M; Habib J; Deleage C; Rosen E; Mattingly C; Bricker K; Kashuba A; Amblard F; Schinazi RF; Lawson B
  • Antibody-Mediated CD4 Depletion Induces Homeostatic CD4+ T Cell Proliferation without Detectable Virus Reactivation in Antiretroviral Therapy-Treated Simian Immunodeficiency Virus-Infected Macaques.
    J Virol Volume: 92
    11/15/2018 Authors: Kumar NA; McBrien JB; Carnathan DG; Mavigner M; Mattingly C; White ER; Viviano F; Bosinger SE; Chahroudi A; Silvestri G
  • Liver Bacterial Dysbiosis Persists During Antiretroviral Therapy of SIV plus Macaques
    Volume: 34 Page(s): 308 - 308
    10/01/2018 Authors: Fisher B; Fisher C; Wood M; Driscoll C; Hensley-McBain T; Smith E; Green R; Gale M; Silvestri G; Chahroudi A
  • A dose-escalation study of pharmacologic inhibition of beta-catenin signaling in healthy rhesus macaques
    Volume: 47 Page(s): 351 - 351
    10/01/2018 Authors: Zanoni M; Mayigner M; Habib J; Mattingly C; Easley K; Kouji H; Chahroudi A
  • Overview of vaccine approaches in adult and infant macaques
    Volume: 47 Page(s): 310 - 310
    10/01/2018 Authors: Chahroudi A
  • CNS Persistence of HIV-1 in Children: the Untapped Reservoir.
    Curr HIV/AIDS Rep Volume: 15 Page(s): 382 - 387
    10/01/2018 Authors: Chahroudi A; Wagner TA; Persaud D
  • An Unusual Cause of Fever and Headache in a School-Aged Male.
    Clin Pediatr (Phila) Volume: 57 Page(s): 1359 - 1362
    10/01/2018 Authors: Joo SJ; Thompson AB; Philipsborn R; Emrath E; Camacho-Gonzalez AF; Chahroudi A; Miller J; Ali I; Cope J
  • Simian Immunodeficiency Virus Persistence in Cellular and Anatomic Reservoirs in Antiretroviral Therapy-Suppressed Infant Rhesus Macaques.
    J Virol Volume: 92
    09/15/2018 Authors: Mavigner M; Habib J; Deleage C; Rosen E; Mattingly C; Bricker K; Kashuba A; Amblard F; Schinazi RF; Lawson B
  • Evaluating Facility Infrastructure for Prevention of Mother-to-Child Transmission of HIV-A 2015 Assessment of Major Delivery Hospitals in Atlanta, Georgia.
    J Pediatric Infect Dis Soc Volume: 7 Page(s): e102 - e106
    08/17/2018 Authors: Smith SL; Chahroudi AM; Camacho-Gonzalez AF; Gillespie S; Wynn BA; Badell ML; Swartzendruber A; Hazra R; Wortley P; Chakraborty R
  • Short-Term Pegylated Interferon 2a Treatment Does Not Significantly Reduce the Viral Reservoir of Simian Immunodeficiency Virus-Infected, Antiretroviral Therapy-Treated Rhesus Macaques.
    J Virol Volume: 92
    07/15/2018 Authors: Palesch D; Bosinger SE; Mavigner M; Billingsley JM; Mattingly C; Carnathan DG; Paiardini M; Chahroudi A; Vanderford TH; Silvestri G
  • Postnatal Zika virus infection is associated with persistent abnormalities in brain structure, function, and behavior in infant macaques.
    Sci Transl Med Volume: 10
    04/04/2018 Authors: Mavigner M; Raper J; Kovacs-Balint Z; Gumber S; O'Neal JT; Bhaumik SK; Zhang X; Habib J; Mattingly C; McDonald CE
  • Liver macrophage-associated inflammation correlates with SIV burden and is substantially reduced following cART.
    PLoS Pathog Volume: 14 Page(s): e1006871
    02/01/2018 Authors: Fisher BS; Green RR; Brown RR; Wood MP; Hensley-McBain T; Fisher C; Chang J; Miller AD; Bosche WJ; Lifson JD
  • Sooty mangabey genome sequence provides insight into AIDS resistance in a natural SIV host.
    Nature Volume: 553 Page(s): 77 - 81
    01/03/2018 Authors: Palesch D; Bosinger SE; Tharp GK; Vanderford TH; Paiardini M; Chahroudi A; Johnson ZP; Kirchhoff F; Hahn BH; Norgren RB
  • Effects of vitamin D supplementation on carotid intima-media thickness in HIV-infected youth.
    Virulence Volume: 9 Page(s): 294 - 305
    01/01/2018 Authors: Eckard AR; Raggi P; O'Riordan MA; Rosebush JC; Labbato D; Chahroudi A; Ruff JH; Longenecker CT; Tangpricha V; McComsey GA
  • Vitamin D supplementation decreases immune activation and exhaustion in HIV-1-infected youth.
    Antivir Ther Volume: 23 Page(s): 315 - 324
    01/01/2018 Authors: Eckard AR; O'Riordan MA; Rosebush JC; Lee ST; Habib JG; Ruff JH; Labbato D; Daniels JE; Uribe-Leitz M; Tangpricha V
  • Effects of Vitamin D Supplementation on Bone Mineral Density and Bone Markers in HIV-Infected Youth.
    J Acquir Immune Defic Syndr Volume: 76 Page(s): 539 - 546
    12/15/2017 Authors: Eckard AR; ORiordan MA; Rosebush JC; Ruff JH; Chahroudi A; Labbato D; Daniels JE; Uribe-Leitz M; Tangpricha V; McComsey GA
  • Neutralizing human monoclonal antibodies prevent Zika virus infection in macaques.
    Sci Transl Med Volume: 9
    10/04/2017 Authors: Magnani DM; Rogers TF; Beutler N; Ricciardi MJ; Bailey VK; Gonzalez-Nieto L; Briney B; Sok D; Le K; Strubel A
  • Using infant animal models to advance pediatric HIV prevention, vaccines and cure
    JOURNAL OF VIRUS ERADICATION Volume: 3 Page(s): 255 - 256
    10/01/2017 Authors: Chahroudi A
  • Sexually Transmitted Infections in Youth With Controlled and Uncontrolled Human Immunodeficiency Virus Infection.
    J Pediatric Infect Dis Soc Volume: 6 Page(s): e22 - e29
    09/01/2017 Authors: Camacho-Gonzalez AF; Chernoff MC; Williams PL; Chahroudi A; Oleske JM; Traite S; Chakraborty R; Purswani MU; Abzug MJ; International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) P1074 Study Team
  • Liver associated inflammation and macrophage infiltration during SIV infection is partly reversed during cART
    Volume: 46 Page(s): 163 - 163
    08/01/2017 Authors: Fisher B; Brown R; Silvestri G; Chahroudi A; Klatt N; Sodora D
  • Inhibiting memory CD4+T cell self-renewal to reduce HIV persistence
    Volume: 20 Page(s): 51 - 51
    07/01/2017 Authors: Mavigner M; Zanoni M; Habib J; Mattingly C; Demarest J; Kouji H; Lawson B; Vanderford T; Tharp G; Bosinger S
  • Correction for Mylvaganam et al., Dynamics of SIV-specific CXCR5+ CD8 T cells during chronic SIV infection.
    Proc Natl Acad Sci U S A Volume: 114 Page(s): E3366
    04/18/2017
  • Dynamics of SIV-specific CXCR5+ CD8 T cells during chronic SIV infection.
    Proc Natl Acad Sci U S A Volume: 114 Page(s): 1976 - 1981
    02/21/2017 Authors: Mylvaganam GH; Rios D; Abdelaal HM; Iyer S; Tharp G; Mavigner M; Hicks S; Chahroudi A; Ahmed R; Bosinger SE
  • Neurocognitive dysfunction in HIV-infected youth: investigating the relationship with immune activation.
    Antivir Ther Volume: 22 Page(s): 669 - 680
    01/01/2017 Authors: Eckard AR; Rosebush JC; O'Riordan MA; Graves CC; Alexander A; Grover AK; Lee ST; Habib JG; Ruff JH; Chahroudi A
  • Increased Immune Activation and Exhaustion in HIV-infected Youth.
    Pediatr Infect Dis J Volume: 35 Page(s): e370 - e377
    12/01/2016 Authors: Eckard AR; Rosebush JC; Lee ST; O'Riordan MA; Habib JG; Daniels JE; Labbato D; Uribe-Leitz M; Chahroudi A; McComsey GA
  • Quantifying integrated SIV-DNA by repetitive-sampling Alu-gag PCR.
    J Virus Erad Volume: 2 Page(s): 219 - 226
    10/05/2016 Authors: Mavigner M; Lee ST; Habib J; Robinson C; Silvestri G; O'Doherty U; Chahroudi A
  • The latest science from the IAS Towards an HIV Cure Symposium: 16-17 July 2016, Durban, South Africa.
    J Virus Erad Volume: 2 Page(s): 235 - 241
    10/05/2016 Authors: Mann J; Pasternak AO; Chahroudi A; Singh JA; Ross AL
  • Induction of Unique Subset of Follicular Homing SIV-specific CD8 T Cells by Vaccination Is Associated with Enhanced Control of Pathogenic SIV
    Volume: 32 Page(s): 85 - 85
    10/01/2016 Authors: Mylvaganam G; Reddy P; Rios D; Mohammad H; Gangadhara S; Turner-Styles T; Iyer S; Hicks S; Tharp G; Mavigner M
  • What pediatric nonprogressors and natural SIV hosts teach us about HIV.
    Sci Transl Med Volume: 8 Page(s): 358fs16
    09/28/2016 Authors: Chahroudi A; Silvestri G
  • CD8(+) Lymphocytes Are Required for Maintaining Viral Suppression in SIV-Infected Macaques Treated with Short-Term Antiretroviral Therapy.
    Immunity Volume: 45 Page(s): 656 - 668
    09/20/2016 Authors: Cartwright EK; Spicer L; Smith SA; Lee D; Fast R; Paganini S; Lawson BO; Nega M; Easley K; Schmitz JE
  • Antiretroviral Therapy in Simian Immunodeficiency Virus-Infected Sooty Mangabeys: Implications for AIDS Pathogenesis.
    J Virol Volume: 90 Page(s): 7541 - 7551
    08/15/2016 Authors: Calascibetta F; Micci L; Carnathan D; Lawson B; Vanderford TH; Bosinger SE; Easley K; Chahroudi A; Mackel J; Keele BF
  • Initiation of Antiretroviral Therapy Restores CD4+ T Memory Stem Cell Homeostasis in Simian Immunodeficiency Virus-Infected Macaques.
    J Virol Volume: 90 Page(s): 6699 - 6708
    08/01/2016 Authors: Cartwright EK; Palesch D; Mavigner M; Paiardini M; Chahroudi A; Silvestri G
  • Animal models to achieve an HIV cure.
    Curr Opin HIV AIDS Volume: 11 Page(s): 432 - 441
    07/01/2016 Authors: Kumar N; Chahroudi A; Silvestri G
  • HIV and Tfh Cells: Circulating New Ideas to Identify and Protect.
    Immunity Volume: 44 Page(s): 16 - 18
    01/19/2016 Authors: Chahroudi A; Silvestri G
  • Correction: Decreased T Follicular Regulatory Cell/T Follicular Helper Cell (T(FH)) in Simian Immunodeficiency Virus-Infected Rhesus Macaques May Contribute to Accumulation of T(FH) in Chronic Infection.
    J Immunol Volume: 195 Page(s): 5843
    12/15/2015 Authors: Chowdhury A; Del Rio Estrada PM; Tharp GK; Trible RP; Amara RR; Chahroudi A; Reyes-Teran G; Bosinger SE; Silvestri G
  • Interleukin-21 combined with ART reduces inflammation and viral reservoir in SIV-infected macaques.
    J Clin Invest Volume: 125 Page(s): 4497 - 4513
    12/01/2015 Authors: Micci L; Ryan ES; Fromentin R; Bosinger SE; Harper JL; He T; Paganini S; Easley KA; Chahroudi A; Benne C
  • Social Stress Impacts the Pathogenesis of SIV Infection and Treatment Response
    Volume: 40 Page(s): S154 - S154
    12/01/2015 Authors: Neigh G; Ethun K; Cartwright E; McGary C; Micci L; Paiardini M; Silvestri G; Chahroudi A
  • Reduced Simian Immunodeficiency Virus Replication in Macrophages of Sooty Mangabeys Is Associated with Increased Expression of Host Restriction Factors.
    J Virol Volume: 89 Page(s): 10136 - 10144
    10/01/2015 Authors: Mir KD; Mavigner M; Wang C; Paiardini M; Sodora DL; Chahroudi AM; Bosinger SE; Silvestri G
  • Decreased T Follicular Regulatory Cell/T Follicular Helper Cell (TFH) in Simian Immunodeficiency Virus-Infected Rhesus Macaques May Contribute to Accumulation of TFH in Chronic Infection.
    J Immunol Volume: 195 Page(s): 3237 - 3247
    10/01/2015 Authors: Chowdhury A; Del Rio Estrada PM; Tharp GK; Trible RP; Amara RR; Chahroudi A; Reyes-Teran G; Bosinger SE; Silvestri G
  • IAS Towards an HIV Cure Symposium: people focused, science driven: 18-19 July 2015, Vancouver, Canada.
    Volume: 1 Page(s): 276 - 281
    10/01/2015 Authors: Fidler S; Thornhill J; Malatinkova E; Reinhard R; Lamplough R; Ananworanich J; Chahroudi A
  • Differential Impact of In Vivo CD8+ T Lymphocyte Depletion in Controller versus Progressor Simian Immunodeficiency Virus-Infected Macaques.
    J Virol Volume: 89 Page(s): 8677 - 8686
    09/01/2015 Authors: Chowdhury A; Hayes TL; Bosinger SE; Lawson BO; Vanderford T; Schmitz JE; Paiardini M; Betts M; Chahroudi A; Estes JD
  • Missed opportunities for prevention of mother-to-child transmission in the United States.
    AIDS Volume: 29 Page(s): 1511 - 1515
    07/31/2015 Authors: Camacho-Gonzalez AF; Kingbo M-H; Boylan A; Eckard AR; Chahroudi A; Chakraborty R
  • The association of uncontrolled HIV infection and other sexually transmitted infections in metropolitan Atlanta youth.
    Pediatr Infect Dis J Volume: 34 Page(s): e119 - e124
    05/01/2015 Authors: Brownstein PS; Gillespie SE; Leong T; Chahroudi A; Chakraborty R; Camacho-Gonzalez AF
  • T memory stem cells and HIV: a long-term relationship.
    Curr HIV/AIDS Rep Volume: 12 Page(s): 33 - 40
    03/01/2015 Authors: Chahroudi A; Silvestri G; Lichterfeld M
  • Transition of youth living with HIV from pediatric to adult-oriented healthcare: a review of the literature (vol 9, pg 921, 2014)
    FUTURE VIROLOGY Volume: 10 Page(s): 463 - 463
    01/01/2015 Authors: Hussen SA; Chahroudi A; Boylan A; Camacho-Gonzalez AF; Hackett S; Chakraborty R
  • Transition of youth living with HIV from pediatric to adult-oriented healthcare: a review of the literature.
    Future Virol Volume: 9 Page(s): 921 - 929
    01/01/2015 Authors: Hussen SA; Chahroudi A; Boylan A; Camacho-Gonzalez AF; Hackett S; Chakraborty R
  • TARGETING SIV RESERVOIRS THROUGH AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANT IN RHESUS MACAQUES
    JOURNAL OF MEDICAL PRIMATOLOGY Volume: 43 Page(s): 380 - 380
    10/01/2014 Authors: Mavigner M; Watkins B; Lawson B; Chahroudi A; Kean L; Silvestri G
  • DIVERGENT CD4+T MEMORY STEM CELL DYNAMICS IN PATHOGENIC AND NONPATHOGENIC SIV INFECTIONS
    JOURNAL OF MEDICAL PRIMATOLOGY Volume: 43 Page(s): 384 - 384
    10/01/2014 Authors: Cartwright E; McGary C; Cervasi B; Lawson B; Bosinger SE; Paiardini M; Vanderford TH; Chahroudi A; Silvestri G
  • TARGET CELL AVAILABILITY, RATHER THAN BREAST MILK SPECIFIC FACTORS, DICTATES MOTHER-TO-INFANT TRANSMISSION OF SIV
    JOURNAL OF MEDICAL PRIMATOLOGY Volume: 43 Page(s): 385 - 385
    10/01/2014 Authors: Chahroudi A; Cartwright E; Carnathan DG; Lee ST; Lawson B; Carnathan PM; Hashempoor T; Murphy MK; Meeker T; Ehnert S
  • Persistence of virus reservoirs in ART-treated SHIV-infected rhesus macaques after autologous hematopoietic stem cell transplant.
    PLoS Pathog Volume: 10 Page(s): e1004406
    09/01/2014 Authors: Mavigner M; Watkins B; Lawson B; Lee ST; Chahroudi A; Kean L; Silvestri G
  • Divergent CD4+ T memory stem cell dynamics in pathogenic and nonpathogenic simian immunodeficiency virus infections.
    J Immunol Volume: 192 Page(s): 4666 - 4673
    05/15/2014 Authors: Cartwright EK; McGary CS; Cervasi B; Micci L; Lawson B; Elliott STC; Collman RG; Bosinger SE; Paiardini M; Vanderford TH
  • Increased stability and limited proliferation of CD4+ central memory T cells differentiate nonprogressive simian immunodeficiency virus (SIV) infection of sooty mangabeys from progressive SIV infection of rhesus macaques.
    J Virol Volume: 88 Page(s): 4533 - 4542
    04/01/2014 Authors: McGary CS; Cervasi B; Chahroudi A; Micci L; Taaffe J; Meeker T; Silvestri G; Davenport MP; Paiardini M
  • Target cell availability, rather than breast milk factors, dictates mother-to-infant transmission of SIV in sooty mangabeys and rhesus macaques.
    PLoS Pathog Volume: 10 Page(s): e1003958
    03/01/2014 Authors: Chahroudi A; Cartwright E; Lee ST; Mavigner M; Carnathan DG; Lawson B; Carnathan PM; Hashempoor T; Murphy MK; Meeker T
  • The oral mucosa immune environment and oral transmission of HIV/SIV.
    Immunol Rev Volume: 254 Page(s): 34 - 53
    07/01/2013 Authors: Wood LF; Chahroudi A; Chen H-L; Jaspan HB; Sodora DL
  • Target cell restriction may limit mother-to-child transmission of SIV in sooty mangabeys
    JOURNAL OF THE INTERNATIONAL AIDS SOCIETY Volume: 15 Page(s): 26 - 26
    10/01/2012 Authors: Chahroudi A; Carnathan D; Carnathan P; Silvestri G
  • Natural SIV hosts: Showing AIDS the door (vol 335, pg 1188, 2012)
    SCIENCE Volume: 336 Page(s): 413 - 413
    04/27/2012 Authors: Chahroudi A
  • IRIS: the unfortunate rainbow of HIV.
    Blood Volume: 119 Page(s): 2971 - 2972
    03/29/2012 Authors: Chahroudi A; Silvestri G
  • Natural SIV hosts: showing AIDS the door.
    Science Volume: 335 Page(s): 1188 - 1193
    03/09/2012 Authors: Chahroudi A; Bosinger SE; Vanderford TH; Paiardini M; Silvestri G
  • Reply to "Control of Simian Immunodeficiency Virus SIVmnd-1 RNA Plasma Viremia after Coinfection or Superinfection with SIVmnd-1 in SIVmnd-2-Infected Mandrills and Vice Versa".
    J Virol Volume: 86 Page(s): 2387 - 2388
    02/01/2012 Authors: Souquiere S; Apetrei C; Chahroudi A; Pandrea I; Silvestri G; Roques P
  • Immunovirological analyses of chronically simian immunodeficiency virus SIVmnd-1- and SIVmnd-2-infected mandrills (Mandrillus sphinx).
    J Virol Volume: 85 Page(s): 13077 - 13087
    12/01/2011 Authors: Apetrei C; Sumpter B; Souquiere S; Chahroudi A; Makuwa M; Reed P; Ribeiro RM; Pandrea I; Roques P; Silvestri G
  • Low levels of SIV infection in sooty mangabey central memory CD T cells are associated with limited CCR5 expression.
    Nat Med Volume: 17 Page(s): 830 - 836
    06/26/2011 Authors: Paiardini M; Cervasi B; Reyes-Aviles E; Micci L; Ortiz AM; Chahroudi A; Vinton C; Gordon SN; Bosinger SE; Francella N
  • Mother-to-infant transmission of simian immunodeficiency virus is rare in sooty mangabeys and is associated with low viremia.
    J Virol Volume: 85 Page(s): 5757 - 5763
    06/01/2011 Authors: Chahroudi A; Meeker T; Lawson B; Ratcliffe S; Else J; Silvestri G
  • Secondary complications and co-infections in the HIV-infected adolescent in the antiretroviral era.
    Curr Opin Infect Dis Volume: 24 Page(s): 212 - 218
    06/01/2011 Authors: Ross AC; Camacho-Gonzalez A; Chahroudi A; Chakraborty R
  • Interleukin-7 inHIV pathogenesis andtherapy.
    Eur Cytokine Netw Volume: 21 Page(s): 202 - 207
    09/01/2010 Authors: Chahroudi A; Silvestri G
  • Lineage-specific T-cell reconstitution following in vivo CD4+ and CD8+ lymphocyte depletion in nonhuman primates.
    Blood Volume: 116 Page(s): 748 - 758
    08/05/2010 Authors: Engram JC; Cervasi B; Borghans JAM; Klatt NR; Gordon SN; Chahroudi A; Else JG; Mittler RS; Sodora DL; de Boer RJ
  • A five-year longitudinal analysis of sooty mangabeys naturally infected with simian immunodeficiency virus reveals a slow but progressive decline in CD4+ T-cell count whose magnitude is not predicted by viral load or immune activation.
    J Virol Volume: 84 Page(s): 5476 - 5484
    06/01/2010 Authors: Taaffe J; Chahroudi A; Engram J; Sumpter B; Meeker T; Ratcliffe S; Paiardini M; Else J; Silvestri G
  • Early resolution of acute immune activation and induction of PD-1 in SIV-infected sooty mangabeys distinguishes nonpathogenic from pathogenic infection in rhesus macaques.
    J Immunol Volume: 180 Page(s): 6798 - 6807
    05/15/2008 Authors: Estes JD; Gordon SN; Zeng M; Chahroudi AM; Dunham RM; Staprans SI; Reilly CS; Silvestri G; Haase AT
  • Differences and similarities in viral life cycle progression and host cell physiology after infection of human dendritic cells with modified vaccinia virus Ankara and vaccinia virus.
    J Virol Volume: 80 Page(s): 8469 - 8481
    09/01/2006 Authors: Chahroudi A; Garber DA; Reeves P; Liu L; Kalman D; Feinberg MB
  • Disabling poxvirus pathogenesis by inhibition of Abl-family tyrosine kinases (vol 11, pg 731, 2005)
    NATURE MEDICINE Volume: 11 Page(s): 1361 - 1361
    12/01/2005 Authors: Reeves PM; Bommarius B; Lebeis S; McNulty S; Christensen J; Swimm A; Chahroudi A; Chavan R; Feinberg MB; Veach D
  • Measurement of HIV-1 CRF02_AG-specific T cell responses indicates the dominance of a p24gag epitope in blood donors in Abidjan, Cote d'Ivoire.
    Volume: 192 Page(s): 1417 - 1421
    10/15/2005 Authors: Chahroudi A; Sawadogo S; Ellenberger D; Pieniazek D; Borget-Alloue M-Y; Aidoo M; Koblavi-Deme S; Fernandez-Vina M; Maurice C; Chorba T
  • Vaccinia virus tropism for primary hematolymphoid cells is determined by restricted expression of a unique virus receptor.
    J Virol Volume: 79 Page(s): 10397 - 10407
    08/01/2005 Authors: Chahroudi A; Chavan R; Kozyr N; Waller EK; Silvestri G; Feinberg MB
  • Disabling poxvirus pathogenesis by inhibition of Abl-family tyrosine kinases.
    Nat Med Volume: 11 Page(s): 731 - 739
    07/01/2005 Authors: Reeves PM; Bommarius B; Lebeis S; McNulty S; Christensen J; Swimm A; Chahroudi A; Chavan R; Feinberg MB; Veach D
  • Measuring T cell-mediated cytotoxicity using fluorogenic caspase substrates.
    Methods Volume: 31 Page(s): 120 - 126
    10/01/2003 Authors: Chahroudi A; Silvestri G; Feinberg MB
  • Visualization and quantification of T cell-mediated cytotoxicity using cell-permeable fluorogenic caspase substrates.
    Nat Med Volume: 8 Page(s): 185 - 189
    02/01/2002 Authors: Liu L; Chahroudi A; Silvestri G; Wernett ME; Kaiser WJ; Safrit JT; Komoriya A; Altman JD; Packard BZ; Feinberg MB
  • Human CD4(+) T lymphocytes consistently respond to the latent Epstein-Barr virus nuclear antigen EBNA1.
    J Exp Med Volume: 191 Page(s): 1649 - 1660
    05/15/2000 Authors: Mnz C; Bickham KL; Subklewe M; Tsang ML; Chahroudi A; Kurilla MG; Zhang D; O'Donnell M; Steinman RM
  • Vaccinia virus inhibits the maturation of human dendritic cells: a novel mechanism of immune evasion.
    J Immunol Volume: 163 Page(s): 6762 - 6768
    12/15/1999 Authors: Engelmayer J; Larsson M; Subklewe M; Chahroudi A; Cox WI; Steinman RM; Bhardwaj N
  • Presentation of epstein-barr virus latency antigens to CD8(+), interferon-gamma-secreting, T lymphocytes.
    Eur J Immunol Volume: 29 Page(s): 3995 - 4001
    12/01/1999 Authors: Subklewe M; Chahroudi A; Bickham K; Larsson M; Kurilla MG; Bhardwaj N; Steinman RM
  • Induction of Epstein-Barr virus-specific cytotoxic T-lymphocyte responses using dendritic cells pulsed with EBNA-3A peptides or UV-inactivated, recombinant EBNA-3A vaccinia virus.
    Blood Volume: 94 Page(s): 1372 - 1381
    08/15/1999 Authors: Subklewe M; Chahroudi A; Schmaljohn A; Kurilla MG; Bhardwaj N; Steinman RM
  • Elispot for the determination of the repertoire of EBV antigens recognized by human T-lymphocytes.
    BLOOD Volume: 92 Page(s): 22A - 23A
    11/15/1998 Authors: Subklewet M; Chahroudi A; Bickham K; Larsson M; Bhardwaj N; Steinmann RM
  • Induction of CTL responses with dendritic cells pulsed with EBNA-3A peptide or recombinant vaccinia-EBNA-3A.
    BLOOD Volume: 92 Page(s): 411A - 411A
    11/15/1998 Authors: Subklewe M; Chahroudi A; Bhardwaj N; Steinman RM
  • Vaccinia virus goes through an abortive replication cycle in dendritic cells and inhibits their maturation
    JOURNAL OF LEUKOCYTE BIOLOGY Page(s): 37 - 37
    01/01/1998 Authors: Engelmayer J; Larsson M; Subklewe M; Chahroudi A; Steinman R; Bhardwaj N
  • Strong, MHC I-restricted, cytolytic T lymphocyte responses to EBV antigen on dendritic cells.
    BLOOD Volume: 90 Page(s): 2033 - 2033
    11/15/1997 Authors: Subklewe M; Chahroudi A; Bhardwaj N; Steinman RM
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