Andrey Ivanov
- Department of Pharmacology & Chemical Biology
Assistant Professor
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Emory University School of Medicine
Pharmacology
615 Michael St., Whitehead Building #405-J
Overview
Research Area: Molecular biology and computational systems pharmacology to identify disease targets and chemical probes.
Research Interests: Dr. Ivanov combines experimental molecular biology with state-of-the-art bioinformatics and computational chemistry to study and regulate the molecular connectivity between the biological pathways. He develops and apply methods of computational molecular modeling, cheminformatics, and virtual screening to facilitate drug discovery and therapeutic development.
Research
Publications
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Uncovering the rewired IAP-JAK regulatory axis as an immune-dependent vulnerability of LKB1-mutant lung cancer.
Nat Commun Volume: 16 Page(s): 2324
03/08/2025 Authors: Shu C; Li J; Rui J; Fan D; Niu Q; Bai R; Cicka D; Doyle S; Wahafu A; Zheng X -
Decoding the functional impact of the cancer genome through protein-protein interactions.
Nat Rev Cancer Volume: 25 Page(s): 189 - 208
03/01/2025 Authors: Fu H; Mo X; Ivanov AA -
Polo-like Kinase 1 Inhibitors Demonstrate In Vitro and In Vivo Efficacy in Preclinical Models of Small Cell Lung Cancer.
Cancers (Basel) Volume: 17
01/28/2025 Authors: Zhang G; Pannucci A; Ivanov AA; Switchenko J; Sun S-Y; Sica GL; Liu Z; Huang Y; Schmitz JC; Owonikoko TK -
Protocol to discover actionable cancer vulnerabilities enabled by neomorph protein-protein interactions with the AVERON Notebook.
STAR Protoc Volume: 5 Page(s): 103441
12/20/2024 Authors: Chen H; Revennaugh B; Fu H; Ivanov AA -
Best practices to evaluate the impact of biomedical research software-metric collection beyond citations.
Bioinformatics Volume: 40
08/02/2024 Authors: Afiaz A; Ivanov AA; Chamberlin J; Hanauer D; Savonen CL; Goldman MJ; Morgan M; Reich M; Getka A; Holmes A -
AVERON notebook to discover actionable cancer vulnerabilities enabled by neomorph protein-protein interactions.
iScience Volume: 27 Page(s): 110035
06/21/2024 Authors: Chen H; Revennaugh B; Fu H; Ivanov AA -
Pharmacological suppression of the OTUD4/CD73 proteolytic axis revives antitumor immunity against immune-suppressive breast cancers.
J Clin Invest Volume: 134
03/26/2024 Authors: Zhu Y; Banerjee A; Xie P; Ivanov AA; Uddin A; Jiao Q; Chi JJ; Zeng L; Lee JY; Xue Y -
Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease.
J Biol Chem Volume: 299 Page(s): 105382
12/01/2023 Authors: Du Y; Bradshaw WJ; Leisner TM; Annor-Gyamfi JK; Qian K; Bashore FM; Sikdar A; Nwogbo FO; Ivanov AA; Frye SV -
TMPRSS2 and SARS-CoV-2 SPIKE interaction assay for uHTS.
J Mol Cell Biol Volume: 15
08/03/2023 Authors: Cicka D; Niu Q; Qui M; Qian K; Miller E; Fan D; Mo X; Ivanov AA; Sarafianos SG; Du Y -
Evaluation of software impact designed for biomedical research: Are we measuring what's meaningful?
ArXiv
06/05/2023 Authors: Afiaz A; Ivanov AA; Chamberlin J; Hanauer D; Savonen CL; Goldman MJ; Morgan M; Reich M; Getka A; Holmes A