2023
June: A new paper led by research fellow Dr. Zhuoyuan Lin is published in Oncogene. Palmitoyl acyltransferase ZDHHC7 inhibits androgen receptor and suppresses prostate cancer.
June: A new paper led by Northwestern University DGP graduate student Galina Gritsina is published in Journal of Clinical Investigation. Chemokine receptor CXCR7 activates Aurora Kinase A and promotes neuroendocrine prostate cancer growth.
May 15: Dr. Yu commented on ferroptosis in cancer, published in Journal of Clinical Investigation.
March: A beautiful review of CXCR7 in advanced prostate cancer written by graduate student Galina Gritsina and Dr. Yu is published in Oncogene.
March 1: J. Yu lab moved to Emory University after nearly 14 years of presence at the Northwestern University.
2022
December 1: New paper published in Mol Cell: PALI1 promotes tumor growth through competitive recruitment of PRC2 to G9A-target chromatin for dual epigenetic silencing.
August 5: New paper published in Oncogene: FOXA1 inhibits hypoxia programs through transcriptional repression of HIF1A.
May 10: Feinberg School of Medicine news: New Regulator of Prostate Cancer Metastasis Discovered.
April 25: Milestone Achievement! New paper published in Nature Genetics: HOXB13 suppresses de novo lipogenesis through HDAC3-mediated epigenetic reprogramming in prostate cancer.
March 22: New postdoc Dr. Ahmad Hasan Othman started in the lab. Welcome, Ahmad!
January 3: New postdoc Dr. Najma Shaheen started in the lab. Welcome, Najma!
2021
September 7: New postdoc Dr. Hongshun Shi started in the lab. Welcome, Hongshun!
August 4: New paper published in Oncogene: Going beyond Polycomb: EZH2 functions in prostate cancer.
July 1: Dr. Shivani Agarwal joined us as a Research Assistant Professor. Welcome, Shivani!
June 1: Sophia Marie Lamperis joined the lab as a DGP graduate student. Welcome, Sophia!
April 20: Feinberg School of Medicine news: Uncovering the Function of Prostate Cancer Protein.
April 7: New paper published in Science Advances: Posttranslational regulation of FOXA1 by Polycomb and BUB3/USP7 deubiquitin complex in prostate cancer.
February 1: New postdoc Dr. Jawad Akhtar joined us from Lahore University of Management Sciences. Welcome, Jawad!
2020
December 11: Dr. Kevin Park has graduated and joined Pfizer. Congratulations, Kevin!
November 30: New postdoc Dr. Wanqing Xie started in the lab. Welcome, Wanqing!
August 19: New paper published in Nature Communications: Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer.
August 14: New paper published in Science Advances: Epithelial cell-specific loss of function of Miz1 causes a spontaneous COPD-like phenotype and up-regulates Ace2 expression in mice.
2019
December 1: Dr. Zhuoyuan Lin joined the lab as a visiting scholar. Welcome, Zhuoyuan!
August 28: New paper published in Oncogene: BMI1 is directly regulated by androgen receptor to promote castration-resistance in prostate cancer.
August 1: New postdocs Dr. Ezinne Mong and Dr. Fang Wang joined us. Welcome!
July 19: New paper published in Cell Research: Altered chromatin recruitment by FOXA1 mutations promotes androgen independence and prostate cancer progression.
July 1: New paper published in Journal of Clinical Investigation: N-Myc-mediated epigenetic reprogramming drives lineage plasticity in advanced prostate cancer.
May 1: Lourdes Brea joined the lab as a DGP graduate student. Welcome, Luly!
April 25: New paper published in American Journal of Clinical and Experimental Urology: Immune modulatory functions of EZH2 in the tumor microenvironment: implications in cancer immunotherapy.
April 5: New paper published in Cancer Research: Activation of MAPK signaling by CXCR7 leads to enzalutamide resistance in prostate cancer.
March 29: New paper published in Asian J Androl: Transcriptional repression by androgen receptor: roles in castration-resistant prostate cancer.
March 14: Feinberg School of Medicine Research Newsletter: Uncovering Genetic and Epigenetic Pathways to Prostate Cancer.
January 23: Feinberg School of Medicine news: Study Suggests New Strategy to Treat Advanced Prostate Cancer.