Hui Mao PhD
- Department of Radiology and Imaging Sciences
Professor
- (404) 712-0357
- hmao@emory.edu
- Emory Winship Cancer Institute
- Emory University School of Medicine
- Google Scholar
- ResearchGate
-
Emory University School of Medicine
Health Sciences Research Building II
1750 Haygood Drive, N121
Overview
Dr. Mao is widely recognized for his expertise in a range of scientific fields, including chemistry, biochemistry, biomaterials, neurosciences, cancer and nanomedicine, with more than 250 peer-reviewed articles published in scientific and medical journals. Dr. Mao is a Distinguished Investigator of the Academy of Radiology and Biomedical Imaging Research, Fellow of the American Institute for Medical and Biological Engineering (AIMBE), and Fellow of the International Society of Magnetic Resonance in Medicine (ISMRM). Regarded as one of the leading experts in the field, he regularly serves on expert review panels and was a Charter Member and past chair of the NIH Study Section for Clinical Molecular Imaging and Probe Development. Dr. Mao currently is associate editor of Radiology: Imaging Cancer. He also is the recipient of multiple teaching awards, including the One-in-a-Hundred Outstanding Mentor Award for the post-doctoral education.
Dr. Mao directs the Precision and Quantitative Imaging and Image-Guided Technology Program and Laboratory of Functional Molecular Imaging and Nanomedicine (LFMI&N), which focuses on developing and utilizing cutting-edge functional and molecular imaging technologies to advance early detection and molecular characterizations of diseases for precision medicine.
Research Focus:
The research projects in Dr. Maos laboratory, which has been supported continuously by NIH grants for more than 20 years, are focusing on developing and utilizing imaging technologies to address biological questions and solve medical problems with strong emphases on translational research and potential clinical applications. His research program attempts to link molecular, cell biology and biomarker discovery to non-invasive imaging of biological and disease events and activities in vivo, and eventually in humans for early detection and molecular characterizations of diseases.
The lab's research contributions and activities are highlighted in the following areas: 1) developing biomarker targeted MRI contrast agents for MRI-based molecular and cellular imaging; 2) developing NMR/MRS based metabolomics to profile cell or tissue metabolites in vivo and ex vivo to investigate the potential metabolite markers for improving the specificity of cancer detection and for early diagnosis of neurodegenerative diseases; 3) developing nanomaterial and nanotechnology for image-guided drug delivery and interventions and in vitro diagnostics; 4) developing clinical applications of advanced MRI technologies for imaging and study of brain functions, brain disorders and diseases, as well as image-guided treatment; and 5) developing machine- and deep-learning based automatic image analysis and diagnostics.
Academic Appointment
- Adjunct Professor of Biomedical Engineering, Department of Biomedical Engineering, Emory University and Georgia Institute of Technology
- Professor of Radiology and Imaging Sciences, Department of Radiology and Imaging Sciences, Emory University School of Medicine
- Affiliated Scientist, Emory Primate Research Center, Emory University
Education
Degrees
- Ph.D. Biophysical Chemistry from Georgia State University
- M.S. in Physical Chemistry from Nanjing University
- B.S. in Chemistry from Nanjing University
Research
Focus
- The research projects in my laboratory are focusing on developing and utilizing imaging technologies, especially magnetic resonance methods, to address biological questions and solve medical problems with strong emphases on translational research and potential clinical applications. We attempt to link molecular, cell biology and biomarker discovery to non-invasive imaging of biological and disease events and activities in vivo, and eventually in human. Our research currently is involved in the following areas:
Publications
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Imaging Cancer-associated Cachexia: Utilizing Clinical Imaging Modalities for Early Diagnosis.
Radiol Imaging Cancer Volume: 7 Page(s): e240291
07/01/2025 Authors: Jiang Y; Zhao Y; Dai J; Yang Q; Tang X; Fu L; Mao H; Peng X-G -
Author Correction: Mitochondrion-specific dendritic lipopeptide liposomes for targeted sub-cellular delivery.
Nat Commun Volume: 16 Page(s): 5405
06/26/2025 Authors: Jiang L; Zhou S; Zhang X; Li C; Ji S; Mao H; Jiang X -
Long-term in vivo monitoring of transplanted mesenchymal stromal cells in colitis mice with magnetic particle imaging.
EBioMedicine Volume: 116 Page(s): 105775
06/01/2025 Authors: Shao T; Gu Z; Liu Y; Wang X; Tang C; Chen N; Wang M; Liu X; Song H; Chen S -
Irisin reverses high-fat diet-induced metabolic dysfunction via activation of brown adipose tissue in mice.
Int J Obes (Lond) Volume: 49 Page(s): 1066 - 1075
06/01/2025 Authors: Dai J; Zhao Y; Chen Y; Jiang Y; Sun R; Tang X; Cui Y; Mao H; Peng X-G -
T1-contrast enhanced MRI generation from multi-parametric MRI for glioma patients with latent tumor conditioning.
Med Phys Volume: 52 Page(s): 2064 - 2073
04/01/2025 Authors: Eidex Z; Safari M; Qiu RLJ; Yu DS; Shu H-K; Mao H; Yang X -
A subtype specific probe for targeted magnetic resonance imaging of M2 tumor-associated macrophages in brain tumors.
Acta Biomater Volume: 194 Page(s): 336 - 351
03/01/2025 Authors: Li Y; Thamizhchelvan AM; Ma H; Padelford J; Zhang Z; Wu T; Gu Q; Wang Z; Mao H -
Cross-shaped windows transformer with self-supervised pretraining for clinically significant prostate cancer detection in bi-parametric MRI.
Med Phys Volume: 52 Page(s): 993 - 1004
02/01/2025 Authors: Li Y; Wynne J; Wang J; Qiu RLJ; Roper J; Pan S; Jani AB; Liu T; Patel PR; Mao H -
Deep learning based apparent diffusion coefficient map generation from multi-parametric MR images for patients with diffuse gliomas.
Med Phys Volume: 52 Page(s): 847 - 855
02/01/2025 Authors: Eidex Z; Safari M; Wynne J; Qiu RLJ; Wang T; Viar-Hernandez D; Shu H-K; Mao H; Yang X -
A [18F]FDG PET based nomogram to predict cancer-associated cachexia and survival outcome: A multi-center study.
Nutrition Volume: 129 Page(s): 112593
01/01/2025 Authors: Jiang Y; Huang M; Zhao Y; Dai J; Yang Q; Tang X; Li X; Cui Y; Zhang J; Sun J -
Shape-dependent cellular uptake of iron oxide nanorods: mechanisms of endocytosis and implications on cell labeling and cellular delivery.
Nanoscale Volume: 16 Page(s): 21398 - 21415
11/28/2024 Authors: Thamizhchelvan AM; Ma H; Wu T; Nguyen D; Padelford J; Whitworth TJ; Li Y; Yang L; Mao H