Rebecca Arnold PhD
- Department of Urology
Assistant Professor
- (404) 778-4925
Overview
In addition to performing her own independent research, Dr. Arnold directs the work of research specialists and medical students during the School of Medicine-sponsored Discovery Project in Dr. John Petros' lab. She is also active in publishing and writing grant proposals.
Dr. Arnold earned her PhD in chemistry/biochemistry from Indiana University at Bloomington. She completed postdoctoral studies at Simon Fraser University in Burnaby, British Columbia, Canada, during which she focused on the basic biochemistry of CTP: phosphatidylcholine cytidylyltransferase, the regulatory enzyme in phosphatidylcholine synthesis. She then engaged in postdoctoral studies at Emory University studying enzymes that generate reactive oxygen in cells, followed by joining the faculty of the Emory Department of Biochemistry. In 2001, she joined the Emory Department of Pathology and Laboratory Medicine, and came to Emory Urology in 2006.
Dr. Arnold's research interests include investigations of reactive oxygen in cancer, mitochondrial DNA mutations in prostate cancer and their relationship to bone metastasis, and racial disparities in prostate cancer. She is also working with other Emory Urology researchers to develop a diagnostic test for screening and detecting liver cancer.
Dr. Arnold is an active educator who teaches and mentors junior researchers, medical students, urology residents, and post-graduate fellows. She lectures both regionally and nationally and has authored multiple scientific journal articles. She is the recipient of the Henry R. Mahler Memorial Award from Indiana University and multiple National Research Service Awards from the National Institute of Health (NIH).
Academic Appointment
- Assistant Professor-Research Track, Department of Urology, Emory University
Education
Degrees
- PhD from Indiana University
- MS from Southern Illinois University
- BS from Southern Illinois University
Research
Publications
-
A Novel Liver Cancer-Selective Histone Deacetylase Inhibitor Is Effective against Hepatocellular Carcinoma and Induces Durable Responses with Immunotherapy.
ACS Pharmacol Transl Sci Volume: 7 Page(s): 3155 - 3169
10/11/2024 Authors: Wu B; Tapadar S; Ruan Z; Sun CQ; Arnold RS; Johnston A; Olugbami JO; Arunsi U; Gaul DA; Petros JA -
A missense SNP in the tumor suppressor SETD2 reduces H3K36me3 and mitotic spindle integrity in Drosophila.
Genetics Volume: 226
04/03/2024 Authors: Brockett JS; Manalo T; Zein-Sabatto H; Lee J; Fang J; Chu P; Feng H; Patil D; Davidson P; Ogan K -
Discovery of 5'-Substituted 5-Fluoro-2'-deoxyuridine Monophosphate Analogs: A Novel Class of Thymidylate Synthase Inhibitors.
ACS Pharmacol Transl Sci Volume: 6 Page(s): 702 - 709
05/12/2023 Authors: Dasari M; Pelly SC; Geng J; Gold HB; Pribut N; Sharma SK; D'Erasmo MP; Bartsch PW; Sun C; Toti K -
Genetic Factors Associated with Prostate Cancer Conversion from Active Surveillance to Treatment.
HGG Adv Volume: 3
01/13/2022 Authors: Jiang Y; Meyers TJ; Emeka AA; Cooley LF; Cooper PR; Lancki N; Helenowski I; Kachuri L; Lin DW; Stanford JL -
Urine-Based Metabolomics and Machine Learning Reveals Metabolites Associated with Renal Cell Carcinoma Stage.
Cancers (Basel) Volume: 13
12/13/2021 Authors: Bifarin OO; Gaul DA; Sah S; Arnold RS; Ogan K; Master VA; Roberts DL; Bergquist SH; Petros JA; Edison AS -
Machine Learning-Enabled Renal Cell Carcinoma Status Prediction Using Multiplatform Urine-Based Metabolomics.
J Proteome Res Volume: 20 Page(s): 3629 - 3641
07/02/2021 Authors: Bifarin OO; Gaul DA; Sah S; Arnold RS; Ogan K; Master VA; Roberts DL; Bergquist SH; Petros JA; Fernndez FM -
A panel of selected serum protein biomarkers for the detection of aggressive prostate cancer.
Theranostics Volume: 11 Page(s): 6214 - 6224
01/01/2021 Authors: Song J; Ma S; Sokoll LJ; Eguez RV; Hti N; Zhang H; Mohr P; Dua R; Patil D; May KD -
Liver-Targeting Class I Selective Histone Deacetylase Inhibitors Potently Suppress Hepatocellular Tumor Growth as Standalone Agents.
Cancers (Basel) Volume: 12
10/23/2020 Authors: Tapadar S; Fathi S; Wu B; Sun CQ; Raji I; Moore SG; Arnold RS; Gaul DA; Petros JA; Oyelere AK -
Molecular characteristics and markers of advanced clear cell renal cell carcinoma: Pitfalls due to intratumoral heterogeneity and identification of genetic alterations associated with metastasis.
Int J Urol Volume: 27 Page(s): 790 - 797
09/01/2020 Authors: Obeng RC; Arnold RS; Ogan K; Master VA; Pattaras JG; Petros JA; Osunkoya AO -
The JNK inhibitor AS602801 Synergizes with Enzalutamide to Kill Prostate Cancer Cells In Vitro and In Vivo and Inhibit Androgen Receptor Expression.
Transl Oncol Volume: 13 Page(s): 100751
04/01/2020 Authors: Li Z; Sun C; Tao S; Osunkoya AO; Arnold RS; Petros JA; Zu X; Moreno CS