School of Medicine Homepage
Emory University Shield
  • About
    • Our Vision
    • Academic Departments
    • Our Leadership
    • Health Care Partnerships
    • Diversity, Equity, & Inclusion
    • Location
    • Supporting Our People
    • Our Faculty
    • History
    • News
    • Events
    • Contact Us
  • Education
    • Degree and Certificate Programs
    • Academic Departments
    • Residents & Fellows
    • Postdoctoral Training
    • Continuing Medical Education
    • Admissions
    • Cost and Financial Aid
    • Student Resources
  • Research
    • Research Innovation
    • Conducting Research
    • Core Facilities
    • Research Centers
    • Research Training
    • Academic Departments
    • Find a Researcher
    • Research News
  • Clinical Experience
    • Where We Work
    • Caring for a Diverse Population
    • Faculty Clinical Experience
    • Advanced Patient Care
    • Academic Departments
    • Community Learning
  • Giving
  • Directory

Directory section navigation

  • Faculty Profiles

Emory University School of Medicine

  • About
    • Sub link
      Our Vision
    • Sub link
      Academic Departments
    • Sub link
      Our Leadership
    • Sub link
      Health Care Partnerships
    • Sub link
      Diversity, Equity, & Inclusion
    • Sub link
      Location
    • Sub link
      Supporting Our People
    • Sub link
      Our Faculty
    • Sub link
      History
    • Sub link
      News
    • Sub link
      Events
    • Sub link
      Contact Us
  • Education
    • Sub link
      Degree and Certificate Programs
    • Sub link
      Academic Departments
    • Sub link
      Residents & Fellows
    • Sub link
      Postdoctoral Training
    • Sub link
      Continuing Medical Education
    • Sub link
      Admissions
    • Sub link
      Cost and Financial Aid
    • Sub link
      Student Resources
  • Research
    • Sub link
      Research Innovation
    • Sub link
      Conducting Research
    • Sub link
      Core Facilities
    • Sub link
      Research Centers
    • Sub link
      Research Training
    • Sub link
      Academic Departments
    • Sub link
      Find a Researcher
    • Sub link
      Research News
  • Clinical Experience
    • Sub link
      Where We Work
    • Sub link
      Caring for a Diverse Population
    • Sub link
      Faculty Clinical Experience
    • Sub link
      Advanced Patient Care
    • Sub link
      Academic Departments
    • Sub link
      Community Learning
  • Giving
  • Directory
  • Home School of Medicine Home
  • Directory

Profile

Lily Yang MD/PhD

  • Department of Surgery
    Professor
  • (404) 778-4269
  • lyang02@emory.edu
  • Lily Yang
  • Emory University
    Surgery
    Clininc C, Room C-4088
Head shot of Lily Yang

Overview

Dr. Yang holds multiple NIH grants and is a translational cancer researcher who specializes in the development of novel cancer imaging and targeted therapeutic agents. Her research experiences include tumor immunology, cancer stem cells, cancer gene therapy, apoptosis resistance, molecular targeted cancer therapy, nanoparticle imaging probes, and theranostic nanoparticles for targeted cancer therapy and imaging. Dr. Yang is a member of the Cancer Cell Biology Research Program at Winship Cancer Institute of Emory University, and holds professional memberships with American Association for Cancer Research, American Society of Nanomedicine, and National Cancer Institute Alliance for Nanotechnology in Cancer.

Her research projects focus on the development of novel cancer nanotechnologies and imaging methods to address the major challenges in clinical oncology of early cancer detection, targeted drug delivery, overcoming drug resistance, assessment of therapeutic response using non-invasive imaging, and image-guided surgery.

Academic Appointment

  • Professor with Tenure, Department of Surgery, Emory University School of Medicine
  • Nancy Panoz Chair of Surgery in Cancer Research, Surgery, Emory University
  • Associate Professor, Department of Radiology and Imaging Sciences, Emory University School of Medicine

Education

Degrees

  • PhD from Brown University
  • Master of Medicine from Institute of Epidemiology & Microbiology, Chinese Academy of Preventive Medicine
  • MD from West China University of Medical Sciences

Research

Focus

  • 1).Development of multifunctional nanoparticles for targeted and image-guided cancer therapy; 2).Novel targeted MR imaging probes for cancer detection; 3).Tumor targeted optical imaging probes for image-guided surgery; 4).Signal pathways and molecular mechanisms that confer aggressive behavior and drug resistance of breast cancer cells (e.g. breast cancer stem cells).

Publications

  • Dual inhibition of oxidative phosphorylation and glycolysis using a hyaluronic acid nanoparticle NOX inhibitor enhanced response to radiotherapy in colorectal cancer.
    Biomaterials Volume: 323 Page(s): 123437
    12/01/2025 Authors: Zhang L; Liu T; Chen M; Gao S; Staley CA; Yang L; Zhu L
  • Muc16CD is a novel CAR Tcell target antigen for the treatment of pancreatic cancer.
    Mol Ther Oncol Volume: 32 Page(s): 200868
    12/19/2024 Authors: Lin HK; Blake DA; Liu T; Freeman R; Lesinski GB; Yang L; Rafiq S
  • Shape-dependent cellular uptake of iron oxide nanorods: mechanisms of endocytosis and implications on cell labeling and cellular delivery.
    Nanoscale Volume: 16 Page(s): 21398 - 21415
    11/28/2024 Authors: Thamizhchelvan AM; Ma H; Wu T; Nguyen D; Padelford J; Whitworth TJ; Li Y; Yang L; Mao H
  • Immunomodulatory nanoparticles activate cytotoxic T cells for enhancement of the effect of cancer immunotherapy.
    Nanoscale Volume: 16 Page(s): 17699 - 17722
    10/03/2024 Authors: Wells K; Liu T; Zhu L; Yang L
  • The magic of small-molecule drugs during ex vivo expansion in adoptive cell therapy.
    Front Immunol Volume: 14 Page(s): 1154566
    01/01/2023 Authors: Zhang H; Passang T; Ravindranathan S; Bommireddy R; Jajja MR; Yang L; Selvaraj P; Paulos CM; Waller EK
  • Non-invasive detection and complementary diagnosis of liver metastases via chemokine receptor 4 imaging.
    Cancer Gene Ther Volume: 29 Page(s): 1827 - 1839
    12/01/2022 Authors: Yang H; Tan S; Qiao J; Xu Y; Gui Z; Meng Y; Dong B; Peng G; Ibhagui OY; Qian W
  • Inhibition of NADPH Oxidase-ROS Signal using Hyaluronic Acid Nanoparticles for Overcoming Radioresistance in Cancer Therapy.
    ACS Nano Volume: 16 Page(s): 18708 - 18728
    11/22/2022 Authors: Zhu L; Zhao Y; Liu T; Chen M; Qian WP; Jiang B; Barwick BG; Zhang L; Styblo TM; Li X
  • Advanced iron oxide nanotheranostics for multimodal and precision treatment of pancreatic ductal adenocarcinoma.
    Wiley Interdiscip Rev Nanomed Nanobiotechnol Volume: 14 Page(s): e1793
    07/01/2022 Authors: Zhu L; Mao H; Yang L
  • Acetylation of KLF5 maintains EMT and tumorigenicity to cause chemoresistant bone metastasis in prostate cancer.
    Nat Commun Volume: 12 Page(s): 1714
    03/17/2021 Authors: Zhang B; Li Y; Wu Q; Xie L; Barwick B; Fu C; Li X; Wu D; Xia S; Chen J
  • In Vivo Evaluation of a Miniaturized Fluorescence Molecular Tomography (FMT) Endoscope for Breast Cancer Detection Using Targeted Nanoprobes.
    Int J Mol Sci Volume: 21
    12/09/2020 Authors: Yang H; Qian W; Yang L; Xie H; Jiang H
  • Correction: Growth differentiation factor 15 mediates epithelial mesenchymal transition and invasion of breast cancers through IGF-1R-FoxM1 signaling.
    Oncotarget Volume: 11 Page(s): 4074 - 4075
    11/03/2020 Authors: Peake BF; Eze SM; Yang L; Castellino RC; Nahta R
  • Going even smaller: Engineering sub-5 nm nanoparticles for improved delivery, biocompatibility, and functionality.
    Wiley Interdiscip Rev Nanomed Nanobiotechnol Volume: 12 Page(s): e1644
    11/01/2020 Authors: Xie M; Xu Y; Huang J; Li Y; Wang L; Yang L; Mao H
  • Targeted Imaging of CD206 Expressing Tumor-Associated M2-like Macrophages Using Mannose-Conjugated Antibiofouling Magnetic Iron Oxide Nanoparticles.
    ACS Appl Bio Mater Volume: 3 Page(s): 4335 - 4347
    07/20/2020 Authors: Li Y; Wu H; Ji B; Qian W; Xia S; Wang L; Xu Y; Chen J; Yang L; Mao H
  • Fan-shaped scanning approach for miniaturized photoacoustic tomography.
    J Biophotonics Volume: 13 Page(s): e201960102
    02/01/2020 Authors: Yang H; Shan T; Yang L; Jiang H
  • Probing and Enhancing Ligand-Mediated Active Targeting of Tumors Using Sub-5 nm Ultrafine Iron Oxide Nanoparticles.
    Theranostics Volume: 10 Page(s): 2479 - 2494
    01/01/2020 Authors: Xu Y; Wu H; Huang J; Qian W; Martinson DE; Ji B; Li Y; Wang YA; Yang L; Mao H
  • Palladium-based nanoparticles for the treatment of advanced melanoma
    Volume: 81 Page(s): AB98 - AB98
    10/01/2019 Authors: Bubley J; Elsey J; Zhu L; Rao S; Sasaki M; Pollack B; Yang L; Arbiser JL
  • NADPH oxidases 4 inhibition using a hyaluronic acid nanoparticle drug delivery system sensitized therapeutic response to chemo and radiotherapy in drug resistant breast cancer
    Volume: 79
    07/01/2019 Authors: Zhu L; Zhao Y; Qian WP; Wang D; Jiang B-H; Yang L
  • Targeted hyaluronic acid nanoparticles improve treatment response in pancreatic cancer
    Volume: 79
    07/01/2019 Authors: Jajja MR; Zhu L; Wang D; Staley CA; El-Rayes B; Kooby DA; Yang L
  • Epigenetic reactivation of BAI1/ADGRB1 suppresses tumor invasion by preventing TGF beta 1-induced mesenchymal switch in glioblastoma
    Volume: 79
    07/01/2019 Authors: Suka S; Yang L; Zhu D; Hashimoto H; Devi NS; Van Meir EG
  • Miniature fluorescence molecular tomography (FMT) endoscope based on a MEMS scanning mirror and an optical fiberscope.
    Phys Med Biol Volume: 64 Page(s): 125015
    06/20/2019 Authors: Yang H; Wang D; Shan T; Dai X; Xie H; Yang L; Jiang H
  • Personalized T cell therapy for metastatic colon cancer.
    Volume: 37
    05/20/2019 Authors: Ravindranathan S; Jajja MR; Waller A; Bommireddy R; Petersen C; Selvaraj P; Yang L; Lesinski GB; El-Rayes BF; Flynn B
  • MicroPET and bio-distribution of [C-11]SR48692, a selective antagonist for neurotensin receptor 1, in a nude mouse model bearing two subcutaneous human pancreatic adenocarcinoma xenografts, MIA PaCa-2
    Volume: 60
    05/01/2019 Authors: Mun J; Yang L; Goodman M; Qian W; Yoon Y; Yu W; Liu T; Liang Z; Parent E
  • Palladium based nanoparticles for the treatment of advanced melanoma.
    Sci Rep Volume: 9 Page(s): 3255
    03/01/2019 Authors: Elsey J; Bubley JA; Zhu L; Rao S; Sasaki M; Pollack BP; Yang L; Arbiser JL
  • The WNT10B Network Is Associated with Survival and Metastases in Chemoresistant Triple-Negative Breast Cancer.
    Cancer Res Volume: 79 Page(s): 982 - 993
    03/01/2019 Authors: El Ayachi I; Fatima I; Wend P; Alva-Ornelas JA; Runke S; Kuenzinger WL; Silva J; Silva W; Gray JK; Lehr S
  • Tumor Penetrating Polymeric Nanoparticle Improves Response in a Drug Resistant Pancreatic Cancer PDX Model
    Volume: 26 Page(s): S6 - S7
    02/01/2019 Authors: Jajja M; Zhu L; Wang D; Staley C; El-Rayes B; Kooby DA; Yang L
  • Biological Events and Barriers to Effective Delivery of Cancer Therapeutics
    Volume: 5 Page(s): 13 - 31
    01/01/2019 Authors: Bozeman EN; Yang L
  • Targeted Drug Delivery and Image-Guided Therapy of Heterogeneous Ovarian Cancer Using HER2-Targeted Theranostic Nanoparticles.
    Theranostics Volume: 9 Page(s): 778 - 795
    01/01/2019 Authors: Satpathy M; Wang L; Zielinski RJ; Qian W; Wang YA; Mohs AM; Kairdolf BA; Ji X; Capala J; Lipowska M
  • Inhibition of breast cancer metastasis to the lungs with UBS109.
    Oncotarget Volume: 9 Page(s): 36102 - 36109
    11/16/2018 Authors: Shoji M; Qian WP; Nagaraju GP; Brat DJ; Pessolano D; Luzietti R; Chennamadhavuni S; Yamaguchi M; Yang L; Liotta DC
  • Palladium based nanoparticles for the treatment of advanced melanoma
    Volume: 138 Page(s): S206 - S206
    05/01/2018 Authors: Rao S; Sasaki M; Elsey J; Zhu L; Yang L; Arbiser J
  • Molecular Imaging of Colonic Neoplasms with Novel Receptor Targeted and NIR-Dye-Labeled Nanoparticles
    Volume: 25 Page(s): S33 - S33
    02/01/2018 Authors: Jajja M; Zhou H; Guy W; Martin D; Kooby DA; Krasinskas A; Mao H; Yang L
  • Nanotechnology Strategies To Advance Outcomes in Clinical Cancer Care.
    ACS Nano Volume: 12 Page(s): 24 - 43
    01/23/2018 Authors: Hartshorn CM; Bradbury MS; Lanza GM; Nel AE; Rao J; Wang AZ; Wiesner UB; Yang L; Grodzinski P
  • Impact of Anti-Biofouling Surface Coatings on the Properties of Nanomaterials and Their Biomedical Applications.
    J Mater Chem B Volume: 6 Page(s): 9 - 24
    01/07/2018 Authors: Li Y; Xu Y; Fleischer CC; Huang J; Lin R; Yang L; Mao H
  • Dual-targeting Wnt and uPA receptors using peptide conjugated ultra-small nanoparticle drug carriers inhibited cancer stem-cell phenotype in chemo-resistant breast cancer.
    Biomaterials Volume: 152 Page(s): 47 - 62
    01/01/2018 Authors: Miller-Kleinhenz J; Guo X; Qian W; Zhou H; Bozeman EN; Zhu L; Ji X; Wang YA; Styblo T; O'Regan R
  • Targeted Molecular Imaging of Pancreatic Cancer with a Miniature Endoscope.
    Appl Sci (Basel) Volume: 7
    12/01/2017 Authors: Dai X; Qian W; Yang H; Yang L; Jiang H
  • Growth differentiation factor 15 mediates epithelial mesenchymal transition and invasion of breast cancers through IGF-1R-FoxM1 signaling.
    Oncotarget Volume: 8 Page(s): 94393 - 94406
    11/07/2017 Authors: Peake BF; Eze SM; Yang L; Castellino RC; Nahta R
  • Exerting Enhanced Permeability and Retention Effect Driven Delivery by Ultrafine Iron Oxide Nanoparticles with T1-T2 Switchable Magnetic Resonance Imaging Contrast.
    ACS Nano Volume: 11 Page(s): 4582 - 4592
    05/23/2017 Authors: Wang L; Huang J; Chen H; Wu H; Xu Y; Li Y; Yi H; Wang YA; Yang L; Mao H
  • Diverse Applications of Nanomedicine.
    ACS Nano Volume: 11 Page(s): 2313 - 2381
    03/28/2017 Authors: Pelaz B; Alexiou C; Alvarez-Puebla RA; Alves F; Andrews AM; Ashraf S; Balogh LP; Ballerini L; Bestetti A; Brendel C
  • Current status of biomarker and targeted nanoparticle development: The precision oncology approach for pancreatic cancer therapy.
    Cancer Lett Volume: 388 Page(s): 139 - 148
    03/01/2017 Authors: Zhu L; Staley C; Kooby D; El-Rays B; Mao H; Yang L
  • Tumor Penetrating Theranostic Nanoparticles for Enhancement of Targeted and Image-guided Drug Delivery into Peritoneal Tumors following Intraperitoneal Delivery.
    Theranostics Volume: 7 Page(s): 1689 - 1704
    01/01/2017 Authors: Gao N; Bozeman EN; Qian W; Wang L; Chen H; Lipowska M; Staley CA; Wang YA; Mao H; Yang L
  • Magnetic nanoparticles for precision oncology: theranostic magnetic iron oxide nanoparticles for image-guided and targeted cancer therapy.
    Nanomedicine (Lond) Volume: 12 Page(s): 73 - 87
    01/01/2017 Authors: Zhu L; Zhou Z; Mao H; Yang L
  • Magnetic Nanoparticle Facilitated Drug Delivery for Cancer Therapy with Targeted and Image-Guided Approaches.
    Adv Funct Mater Volume: 26 Page(s): 3818 - 3836
    06/14/2016 Authors: Huang J; Li Y; Orza A; Lu Q; Guo P; Wang L; Yang L; Mao H
  • IGF-1 receptor targeted nanoparticles for image-guided therapy of stroma-rich and drug resistant human cancer.
    Proc SPIE Int Soc Opt Eng Volume: 9836
    04/17/2016 Authors: Zhou H; Qian W; Uckun FM; Zhou Z; Wang L; Wang A; Mao H; Yang L
  • Rationally designed theranostic nanoparticles for applications of precision oncology for image-guided cancer treatment
    Volume: 251
    03/13/2016 Authors: Yang L
  • Enhancing tumor delivery and targeting with sub-5 nm ultrafine magnetic nanoparticles and anti-biofouling coating
    Volume: 251
    03/13/2016 Authors: Mao H; Huang J; Li Y; Wang L; Yang L
  • Nanotubes-Embedded Indocyanine Green-Hyaluronic Acid Nanoparticles for Photoacoustic-Imaging-Guided Phototherapy.
    ACS Appl Mater Interfaces Volume: 8 Page(s): 5608 - 5617
    03/02/2016 Authors: Wang G; Zhang F; Tian R; Zhang L; Fu G; Yang L; Zhu L
  • Plasma membrane vesicles decorated with glycolipid-anchored antigens and adjuvants via protein transfer as an antigen delivery platform for inhibition of tumor growth.
    Biomaterials Volume: 74 Page(s): 231 - 244
    01/01/2016 Authors: Patel JM; Vartabedian VF; Bozeman EN; Caoyonan BE; Srivatsan S; Pack CD; Dey P; D'Souza MJ; Yang L; Selvaraj P
  • A nanocomposite of Au-AgI core/shell dimer as a dual-modality contrast agent for x-ray computed tomography and photoacoustic imaging.
    Med Phys Volume: 43 Page(s): 589
    01/01/2016 Authors: Orza A; Yang Y; Feng T; Wang X; Wu H; Li Y; Yang L; Tang X; Mao H
  • Targeted Delivery with Imaging Assessment of siRNA Expressing Nanocassettes into Cancer.
    Methods Mol Biol Volume: 1372 Page(s): 49 - 59
    01/01/2016 Authors: Chen W; Yang L
  • Functionalized milk-protein-coated magnetic nanoparticles for MRI-monitored targeted therapy of pancreatic cancer.
    Int J Nanomedicine Volume: 11 Page(s): 3087 - 3099
    01/01/2016 Authors: Huang J; Qian W; Wang L; Wu H; Zhou H; Wang AY; Chen H; Yang L; Mao H
  • IGF1 Receptor Targeted Theranostic Nanoparticles for Targeted and Image-Guided Therapy of Pancreatic Cancer.
    ACS Nano Volume: 9 Page(s): 7976 - 7991
    08/25/2015 Authors: Zhou H; Qian W; Uckun FM; Wang L; Wang YA; Chen H; Kooby D; Yu Q; Lipowska M; Staley CA
  • Image-guided and targeted therapy of advanced ovarian cancer using theranostic nanoparticles
    Volume: 21
    08/15/2015 Authors: Yang L; Satpathy M; Wang L; Zielinski R; Qian W; Lipowska M; Capala J; Wang A; Mao H
  • PEG-b-AGE Polymer Coated Magnetic Nanoparticle Probes with Facile Functionalization and Anti-fouling Properties for Reducing Non-specific Uptake and Improving Biomarker Targeting.
    J Mater Chem B Volume: 3 Page(s): 3591 - 3603
    05/07/2015 Authors: Li Y; Lin R; Wang L; Huang J; Wu H; Cheng G; Zhou Z; MacDonald T; Yang L; Mao H
  • Optical imaging of ovarian cancer using HER-2 affibody conjugated nanoparticles.
    Methods Mol Biol Volume: 1219 Page(s): 171 - 185
    01/01/2015 Authors: Satpathy M; Zielinski R; Lyakhov I; Yang L
  • Theranostic nanoparticles carrying doxorubicin attenuate targeting ligand specific antibody responses following systemic delivery.
    Theranostics Volume: 5 Page(s): 43 - 61
    01/01/2015 Authors: Yang E; Qian W; Cao Z; Wang L; Bozeman EN; Ward C; Yang B; Selvaraj P; Lipowska M; Wang YA
  • Preclinical evaluation of a urokinase plasminogen activator receptor-targeted nanoprobe in rhesus monkeys.
    Int J Nanomedicine Volume: 10 Page(s): 6689 - 6698
    01/01/2015 Authors: Chen Y; Gong L; Gao N; Liao J; Sun J; Wang Y; Wang L; Zhu P; Fan Q; Wang YA
  • Targeted nanoparticles for image-guided treatment of triple-negative breast cancer: clinical significance and technological advances.
    Wiley Interdiscip Rev Nanomed Nanobiotechnol Volume: 7 Page(s): 797 - 816
    01/01/2015 Authors: Miller-Kleinhenz JM; Bozeman EN; Yang L
  • Correlation between epidermal growth factor receptor and tumor stem cell markers CD44/CD24 and their relationship with prognosis in breast invasive ductal carcinoma.
    Med Oncol Volume: 32 Page(s): 275
    01/01/2015 Authors: Zheng Z; Shao N; Weng H; Li W; Zhang J; Zhang L; Yang L; Ye S
  • Ultrashort echo time (UTE) imaging of receptor targeted magnetic iron oxide nanoparticles in mouse tumor models.
    J Magn Reson Imaging Volume: 40 Page(s): 1071 - 1081
    11/01/2014 Authors: Wang L; Zhong X; Qian W; Huang J; Cao Z; Yu Q; Lipowska M; Lin R; Wang A; Yang L
  • Targeted therapy of pancreatic cancer by intraperitoneal delivery of uPAR-targeted theranostic nanoparticles
    Volume: 74
    10/01/2014 Authors: Gao N; Bozeman E; Qian W; Staley C; Wang A; Mao H; Yang L
  • Activation of tumor specific antibody response following systemic delivery of receptor targeted nanoparticles into Balb/c mice bearing mouse mammary tumors
    Volume: 74
    10/01/2014 Authors: Ward C; Qian W; Yang E; Bozeman E; Wang YA; Yang L
  • Down-regulation of Wnt10b following targeted theranostic nanoparticles in a patient derived xenograft model of triple negative breast cancer
    Volume: 74
    10/01/2014 Authors: Miller-Kleinhenz J; Qian W; O'Regan R; Styblo T; Zelnak A; Wang A; Yang L
  • Molecular photoacoustic tomography of breast cancer using receptor targeted magnetic iron oxide nanoparticles as contrast agents.
    J Biophotonics Volume: 7 Page(s): 401 - 409
    06/01/2014 Authors: Xi L; Grobmyer SR; Zhou G; Qian W; Yang L; Jiang H
  • Photoacoustic and fluorescence image-guided surgery using a multifunctional targeted nanoprobe.
    Ann Surg Oncol Volume: 21 Page(s): 1602 - 1609
    05/01/2014 Authors: Xi L; Zhou G; Gao N; Yang L; Gonzalo DA; Hughes SJ; Jiang H
  • HER-2/neu targeted delivery of a nanoprobe enables dual photoacoustic and fluorescence tomography of ovarian cancer.
    Nanomedicine Volume: 10 Page(s): 669 - 677
    04/01/2014 Authors: Xi L; Satpathy M; Zhao Q; Qian W; Yang L; Jiang H
  • Active targeting using HER-2-affibody-conjugated nanoparticles enabled sensitive and specific imaging of orthotopic HER-2 positive ovarian tumors.
    Small Volume: 10 Page(s): 544 - 555
    02/12/2014 Authors: Satpathy M; Wang L; Zielinski R; Qian W; Lipowska M; Capala J; Lee GY; Xu H; Wang YA; Mao H
  • Facile non-hydrothermal synthesis of oligosaccharides coated sub-5 nm magnetic iron oxide nanoparticles with dual MRI contrast enhancement effect.
    J Mater Chem B
    01/01/2014 Authors: Huang J; Wang L; Zhong X; Li Y; Yang L; Mao H
  • Nanoparticles for cancer imaging: The good, the bad, and the promise.
    Nano Today Volume: 8 Page(s): 454 - 460
    10/01/2013 Authors: Chapman S; Dobrovolskaia M; Farahani K; Goodwin A; Joshi A; Lee H; Meade T; Pomper M; Ptak K; Rao J
  • uPAR-targeted theranostic nanoparticles effectively decrease expression of IGF-1R and Ki67 in drug-resistant triple-negative breast cancer human xenograft
    MOLECULAR CANCER RESEARCH Volume: 11
    10/01/2013 Authors: Miller-Kleinhenz JM; Zhou H; Qian W; O'Regan R; Zelnak A; Styblo T; Yang L
  • A dual-modal magnetic nanoparticle probe for preoperative and intraoperative mapping of sentinel lymph nodes by magnetic resonance and near infrared fluorescence imaging.
    J Biomater Appl Volume: 28 Page(s): 100 - 111
    07/01/2013 Authors: Zhou Z; Chen H; Lipowska M; Wang L; Yu Q; Yang X; Tiwari D; Yang L; Mao H
  • Casein-coated iron oxide nanoparticles for high MRI contrast enhancement and efficient cell targeting.
    ACS Appl Mater Interfaces Volume: 5 Page(s): 4632 - 4639
    06/12/2013 Authors: Huang J; Wang L; Lin R; Wang AY; Yang L; Kuang M; Qian W; Mao H
  • Targeted delivery of siRNA-generating DNA nanocassettes using multifunctional nanoparticles.
    Small Volume: 9 Page(s): 1964 - 1973
    06/10/2013 Authors: Cho Y-S; Lee GY; Sajja HK; Qian W; Cao Z; He W; Karna P; Chen X; Mao H; Wang YA
  • Multimodality imaging of ovarian cancer using HER2 affibody conjugated nanoparticles.
    Volume: 73
    04/15/2013 Authors: Satpathy M; Qian W; Zielinski R; Wang L; Xi L; Capala J; Wang A; Lipowska M; Kairdolf BA; Jiang H
  • Theranostic Nanoparticles for Targeting Drug Resistant Triple Negative Breast Cancer
    Volume: 27
    04/01/2013 Authors: Miller-Kleinhenz J; Qian W; Zhou H; Wang YA; Mao H; Yang L
  • Theranostic nanoparticles with controlled release of gemcitabine for targeted therapy and MRI of pancreatic cancer.
    ACS Nano Volume: 7 Page(s): 2078 - 2089
    03/26/2013 Authors: Lee GY; Qian WP; Wang L; Wang YA; Staley CA; Satpathy M; Nie S; Mao H; Yang L
  • Handheld miniature probe integrating diffuse optical tomography with photoacoustic imaging through a MEMS scanning mirror.
    Biomed Opt Express Volume: 4 Page(s): 427 - 432
    03/01/2013 Authors: Yang H; Xi L; Samuelson S; Xie H; Yang L; Jiang H
  • DOT corrected fluorescence molecular tomography using targeted contrast agents for small animal tumor imaging.
    J Xray Sci Technol Volume: 21 Page(s): 43 - 52
    01/01/2013 Authors: Tan Y; Cao Z; Sajja HK; Lipowska M; Wang YA; Yang L; Jiang H
  • uPAR-targeted optical imaging contrasts as theranostic agents for tumor margin detection.
    Theranostics Volume: 4 Page(s): 106 - 118
    01/01/2013 Authors: Yang L; Sajja HK; Cao Z; Qian W; Bender L; Marcus AI; Lipowska M; Wood WC; Wang YA
  • Anti-HER2 antibody and ScFvEGFR-conjugated antifouling magnetic iron oxide nanoparticles for targeting and magnetic resonance imaging of breast cancer.
    Int J Nanomedicine Volume: 8 Page(s): 3781 - 3794
    01/01/2013 Authors: Chen H; Wang L; Yu Q; Qian W; Tiwari D; Yi H; Wang AY; Huang J; Yang L; Mao H
  • Endothelial and Cancer Stem Cell Regulation of Tumor Angiogenesis
    Page(s): 91 - 111
    01/01/2013 Authors: Liu M; Yang L; Guo S; Gonzalez-Perez RR
  • Regulation of Angiogenesis via Notch Signaling in Human Malignancy
    Page(s): 37 - 90
    01/01/2013 Authors: Guo S; Liu M; Wang G; Yang L; Gonzalez-Perez RR
  • Microelectromechanical systems scanning-mirror-based handheld probe for fluorescence molecular tomography.
    Appl Opt Volume: 51 Page(s): 4678 - 4683
    07/10/2012 Authors: He B; Xi L; Samuelson SR; Xie H; Yang L; Jiang H
  • IMAGE-GUIDED AND TARGETED THERAPY USING THERANOSTIC NANOPARTICLES FOR PERSONALIZED CANCER TREATMENT
    Volume: 23 Page(s): 26 - 27
    06/01/2012 Authors: Yang L
  • Surface modifications and drug-loading affect immunogenicity of targeted nanoparticles
    CANCER RESEARCH Volume: 72
    04/15/2012 Authors: Yang E; Qian W; Wang A; Bozeman E; Selvaraj P; Mao H; Yang L
  • Improving the magnetic resonance imaging contrast and detection methods with engineered magnetic nanoparticles.
    Theranostics Volume: 2 Page(s): 86 - 102
    01/01/2012 Authors: Huang J; Zhong X; Wang L; Yang L; Mao H
  • Antibody conjugated magnetic iron oxide nanoparticles for cancer cell separation in fresh whole blood.
    Biomaterials Volume: 32 Page(s): 9758 - 9765
    12/01/2011 Authors: Xu H; Aguilar ZP; Yang L; Kuang M; Duan H; Xiong Y; Wei H; Wang A
  • A handheld fluorescence molecular tomography system for intraoperative optical imaging of tumor margins.
    Med Phys Volume: 38 Page(s): 5873 - 5878
    11/01/2011 Authors: Zhao Q; Jiang H; Cao Z; Yang L; Mao H; Lipowska M
  • Detection of survivin expression in cervical cancer cells using molecular beacon imaging: new strategy for the diagnosis of cervical cancer.
    Eur J Obstet Gynecol Reprod Biol Volume: 159 Page(s): 204 - 208
    11/01/2011 Authors: Xue Y; An R; Zhang D; Zhao J; Wang X; Yang L; He D
  • Combinatorial effects of lapatinib and rapamycin in triple-negative breast cancer cells.
    Mol Cancer Ther Volume: 10 Page(s): 1460 - 1469
    08/01/2011 Authors: Liu T; Yacoub R; Taliaferro-Smith LD; Sun S-Y; Graham TR; Dolan R; Lobo C; Tighiouart M; Yang L; Adams A
  • Survivin upregulation, dependent on leptin-EGFR-Notch1 axis, is essential for leptin-induced migration of breast carcinoma cells.
    Endocr Relat Cancer Volume: 18 Page(s): 413 - 428
    08/01/2011 Authors: Knight BB; Oprea-Ilies GM; Nagalingam A; Yang L; Cohen C; Saxena NK; Sharma D
  • Development of theranostic nanoparticles for targeted tumor imaging and treatment of HER-2/neu positive cancer
    CANCER RESEARCH Volume: 71
    04/15/2011 Authors: Satpathy M; Qian W; Capala J; Yang L
  • Theranostic nanoparticles for targeted therapy of pancreatic and triple negative breast cancers
    CANCER RESEARCH Volume: 71
    04/15/2011 Authors: Yang L
  • Current and future clinical applications for optical imaging of cancer: from intraoperative surgical guidance to cancer screening.
    Semin Oncol Volume: 38 Page(s): 109 - 118
    02/01/2011 Authors: Hadjipanayis CG; Jiang H; Roberts DW; Yang L
  • T-weighted ultrashort echo time method for positive contrast imaging of magnetic nanoparticles and cancer cells bound with the targeted nanoparticles.
    J Magn Reson Imaging Volume: 33 Page(s): 194 - 202
    01/01/2011 Authors: Zhang L; Zhong X; Wang L; Chen H; Wang YA; Yeh J; Yang L; Mao H
  • Delivery of therapeutic radioisotopes using nanoparticle platforms: potential benefit in systemic radiation therapy.
    Nanotechnol Sci Appl Volume: 3 Page(s): 159 - 170
    12/03/2010 Authors: Zhang L; Chen H; Wang L; Liu T; Yeh J; Lu G; Yang L; Mao H
  • Reducing non-specific binding and uptake of nanoparticles and improving cell targeting with an antifouling PEO-b-PgammaMPS copolymer coating.
    Biomaterials Volume: 31 Page(s): 5397 - 5407
    07/01/2010 Authors: Chen H; Wang L; Yeh J; Wu X; Cao Z; Wang YA; Zhang M; Yang L; Mao H
  • uPAR Targeted SPECT imaging probes for detection of breast cancer
    Volume: 51
    05/01/2010 Authors: Lipowska M; Sajja H; Yang L
  • c-FLIP degradation mediates sensitization of pancreatic cancer cells to TRAIL-induced apoptosis by the histone deacetylase inhibitor LBH589.
    PLoS One Volume: 5 Page(s): e10376
    04/28/2010 Authors: Kauh J; Fan S; Xia M; Yue P; Yang L; Khuri FR; Sun S-Y
  • Abundance of a distinct cluster of telomere t-stumps in advanced breast cancer cell line.
    Oncol Lett Volume: 1 Page(s): 339 - 343
    03/01/2010 Authors: Pai RB; Pai SB; Yang L; Joshi HC
  • In vivo magnetic enrichment and multiplex photoacoustic detection of circulating tumour cells.
    Nat Nanotechnol Volume: 4 Page(s): 855 - 860
    12/01/2009 Authors: Galanzha EI; Shashkov EV; Kelly T; Kim J-W; Yang L; Zharov VP
  • Multiplexed fluorescence imaging of tumor biomarkers in gene expression and protein levels for personalized and predictive medicine.
    Curr Mol Med Volume: 9 Page(s): 1017 - 1023
    11/01/2009 Authors: Smith MQ; Staley CA; Kooby DA; Styblo T; Wood WC; Yang L
  • Designing caspase-3 sensors for imaging of apoptosis in living cells.
    Chemistry Volume: 15 Page(s): 9311 - 9314
    09/21/2009 Authors: Chen N; Huang Y; Yang L; Liu R; Yang JJ
  • Receptor-targeted nanoparticles for in vivo imaging of breast cancer.
    Clin Cancer Res Volume: 15 Page(s): 4722 - 4732
    07/15/2009 Authors: Yang L; Peng X-H; Wang YA; Wang X; Cao Z; Ni C; Karna P; Zhang X; Wood WC; Gao X
  • Effect of mTOR inhibition on sensitivity of triple-negative breast cancer cells to epidermal growth factor inhibition.
    J Clin Oncol Volume: 27 Page(s): 1055
    05/20/2009 Authors: Liu T; Yacoub R; Graham T; Yang L; Tighiouart M; O'Regan RM
  • Leptin induces migration of breast cancer cells via upregulation of anti-apoptotic protein, survivin
    CANCER RESEARCH Volume: 69
    05/01/2009 Authors: Knight BB; Oberlick E; Nagalingam A; Taliaferro-Smith L; Karna P; Yang L; Saxena N; Sharma D
  • Molecular imaging of pancreatic cancer in an animal model using targeted multifunctional nanoparticles.
    Gastroenterology Volume: 136 Page(s): 1514 - 25.e2
    05/01/2009 Authors: Yang L; Mao H; Cao Z; Wang YA; Peng X; Wang X; Sajja HK; Wang L; Duan H; Ni C
  • Development of multifunctional nanoparticles for targeted drug delivery and noninvasive imaging of therapeutic effect.
    Curr Drug Discov Technol Volume: 6 Page(s): 43 - 51
    03/01/2009 Authors: Sajja HK; East MP; Mao H; Wang YA; Nie S; Yang L
  • Single chain epidermal growth factor receptor antibody conjugated nanoparticles for in vivo tumor targeting and imaging.
    Small Volume: 5 Page(s): 235 - 243
    02/01/2009 Authors: Yang L; Mao H; Wang YA; Cao Z; Peng X; Wang X; Duan H; Ni C; Yuan Q; Adams G
  • Activation of EGFR signaling in CD44 positive cells promotes aggressive behavior and progression of breast cancer
    Volume: 69 Page(s): 317S - 317S
    01/15/2009 Authors: Karna P; Cao Z; Oprea G; Cohen C; Harris W; Waller EK; O'Regan R; Wood WC; Yang L
  • Multifunctional and multiplexed nanoparticles for molecular imaging and treatment of breast cancer
    Volume: 69 Page(s): 348S - 348S
    01/15/2009 Authors: Yang L; Sajja H; Cao Z; Wang AY; Smith MQ; Bender L; Mao H; Nie S; Wood WC
  • Development of Receptor Targeted Magnetic Iron Oxide Nanoparticles for Efficient Drug Delivery and Tumor Imaging.
    J Biomed Nanotechnol Volume: 4 Page(s): 439 - 449
    12/01/2008 Authors: Yang L; Cao Z; Sajja HK; Mao H; Wang L; Geng H; Xu H; Jiang T; Wood WC; Nie S
  • Imaging of urokinase-type plasminogen activator receptor expression using a 64Cu-labeled linear peptide antagonist by microPET.
    Clin Cancer Res Volume: 14 Page(s): 4758 - 4766
    08/01/2008 Authors: Li Z-B; Niu G; Wang H; He L; Yang L; Ploug M; Chen X
  • EGFR signal activated HIF-1 alpha/survivin pathway confers apoptosis resistance in CD 44+breast cancer stem cells
    Volume: 68
    05/01/2008 Authors: Karna P; Cao Z; Harris W; Oprea G; O'Reagan R; Waller E; Wood W; Yang L
  • The effect of HIF-1alpha siRNA on growth and chemosensitivity of MIA-paca cell line.
    Yonsei Med J Volume: 49 Page(s): 295 - 300
    04/30/2008 Authors: Yang L; Kang W-K
  • Shb gene knockdown increases the susceptibility of SVR endothelial tumor cells to apoptotic stimuli in vitro and in vivo.
    J Invest Dermatol Volume: 128 Page(s): 710 - 716
    03/01/2008 Authors: Funa NS; Reddy K; Bhandarkar S; Kurenova EV; Yang L; Cance WG; Welsh M; Arbiser JL
  • In vivo tumor targeting and spectroscopic detection with surface-enhanced Raman nanoparticle tags.
    Nat Biotechnol Volume: 26 Page(s): 83 - 90
    01/01/2008 Authors: Qian X; Peng X-H; Ansari DO; Yin-Goen Q; Chen GZ; Shin DM; Yang L; Young AN; Wang MD; Nie S
  • Application of nanotechnology in cancer therapy and imaging.
    CA Cancer J Clin Volume: 58 Page(s): 97 - 110
    01/01/2008 Authors: Wang X; Yang L; Chen ZG; Shin DM
  • PI3K/PTEN/AKT signaling regulates prostate tumor angiogenesis.
    Cell Signal Volume: 19 Page(s): 2487 - 2497
    12/01/2007 Authors: Fang J; Ding M; Yang L; Liu L-Z; Jiang B-H
  • Down-regulation of inhibitor of apoptosis proteins by deguelin selectively induces apoptosis in breast cancer cells.
    Mol Pharmacol Volume: 71 Page(s): 101 - 111
    01/01/2007 Authors: Peng X-H; Karna P; O'Regan RM; Liu X; Naithani R; Moriarty RM; Wood WC; Lee H-Y; Yang L
  • Quantification of the heterogeneity in breast cancer cell lines using whole-cell impedance spectroscopy.
    Clin Cancer Res Volume: 13 Page(s): 139 - 143
    01/01/2007 Authors: Han A; Yang L; Frazier AB
  • Molecular mechanism of upregulation of survivin transcription by the AT-rich DNA-binding ligand, Hoechst33342: evidence for survivin involvement in drug resistance.
    Nucleic Acids Res Volume: 35 Page(s): 2390 - 2402
    01/01/2007 Authors: Wu J; Apontes P; Song L; Liang P; Yang L; Li F
  • The effect of HIF1Y alpha siRNA on growth and chemosensitivity in cancer cell line
    Volume: 18 Page(s): VII64 - VII64
    01/01/2007 Authors: Kang WK; Cao Z; Park JK; An CH; Yang L
  • Cross-talk between epidermal growth factor receptor and hypoxia-inducible factor-1alpha signal pathways increases resistance to apoptosis by up-regulating survivin gene expression.
    J Biol Chem Volume: 281 Page(s): 25903 - 25914
    09/08/2006 Authors: Peng X-H; Karna P; Cao Z; Jiang B-H; Zhou M; Yang L
  • Quantum dots and multifunctional nanoparticles: new contrast agents for tumor imaging.
    Nanomedicine (Lond) Volume: 1 Page(s): 209 - 217
    08/01/2006 Authors: Rhyner MN; Smith AM; Gao X; Mao H; Yang L; Nie S
  • KLF5 Interacts with p53 in regulating survivin expression in acute lymphoblastic leukemia.
    J Biol Chem Volume: 281 Page(s): 14711 - 14718
    05/26/2006 Authors: Zhu N; Gu L; Findley HW; Chen C; Dong J-T; Yang L; Zhou M
  • Engineering multi-functional quantum dots for in vivo imaging and therapy of breast cancer
    Volume: 66
    04/01/2006 Authors: Peng X-H; Gao X-H; Wang Y; Qinh AY; Admas G; Nie S; William W; Yang L
  • Differential expression of survivin-2B and survivin-DeltaEx3 is inversely associated with disease relapse and patient survival in non-small-cell lung cancer (NSCLC).
    Lung Cancer Volume: 49 Page(s): 353 - 361
    09/01/2005 Authors: Ling X; Yang J; Tan D; Ramnath N; Younis T; Bundy BN; Slocum HK; Yang L; Zhou M; Li F
  • Molecular beacon imaging of tumor marker gene expression in pancreatic cancer cells.
    Cancer Biol Ther Volume: 4 Page(s): 561 - 570
    05/01/2005 Authors: Yang L; Cao Z; Lin Y; Wood WC; Staley CA
  • Real-time detection of gene expression in cancer cells using molecular beacon imaging: new strategies for cancer research.
    Cancer Res Volume: 65 Page(s): 1909 - 1917
    03/01/2005 Authors: Peng X-H; Cao Z-H; Xia J-T; Carlson GW; Lewis MM; Wood WC; Yang L
  • In vivo molecular and cellular imaging with quantum dots.
    Curr Opin Biotechnol Volume: 16 Page(s): 63 - 72
    02/01/2005 Authors: Gao X; Yang L; Petros JA; Marshall FF; Simons JW; Nie S
  • Tumor-specific gene expression using the survivin promoter is further increased by hypoxia.
    Gene Ther Volume: 11 Page(s): 1215 - 1223
    08/01/2004 Authors: Yang L; Cao Z; Li F; Post DE; Van Meir EG; Zhong H; Wood WC
  • Coexistence of high levels of apoptotic signaling and inhibitor of apoptosis proteins in human tumor cells: implication for cancer specific therapy.
    Cancer Res Volume: 63 Page(s): 6815 - 6824
    10/15/2003 Authors: Yang L; Cao Z; Yan H; Wood WC
  • Can we select which patients with small breast cancers should receive adjuvant chemotherapy?
    Ann Surg Volume: 235 Page(s): 859 - 862
    06/01/2002 Authors: Wood WC; Anderson M; Lyles RH; Styblo TM; Murray D; Staley C; Yang L; Carlson G
  • BD.1, a ductal protein associated with preneoplasia in rat prostate epithelial cells
    FASEB JOURNAL Volume: 15 Page(s): A240 - A240
    03/07/2001 Authors: Frenkl TL; McBride AC; Carreiro M; Yang L; Hixson DC
  • Intercellular communication mediates the bystander effect during herpes simplex thymidine kinase/ganciclovir-based gene therapy of human gastrointestinal tumor cells.
    Hum Gene Ther Volume: 9 Page(s): 719 - 728
    03/20/1998 Authors: Yang L; Chiang Y; Lenz HJ; Danenberg KD; Spears CP; Gordon EM; Anderson WF; Parekh D
  • Mechanisms for ganciclovir resistance in gastrointestinal tumor cells transduced with a retroviral vector containing the herpes simplex virus thymidine kinase gene.
    Clin Cancer Res Volume: 4 Page(s): 731 - 741
    03/01/1998 Authors: Yang L; Hwang R; Chiang Y; Gordon EM; Anderson WF; Parekh D
  • Antigenic phenotypes common to rat oval cells, primary hepatocellular carcinomas and developing bile ducts.
    Carcinogenesis Volume: 18 Page(s): 1169 - 1175
    06/01/1997 Authors: Hixson DC; Chapman L; McBride A; Faris R; Yang L
  • Gene therapy of metastatic pancreas cancer with intraperitoneal injections of concentrated retroviral herpes simplex thymidine kinase vector supernatant and ganciclovir.
    Ann Surg Volume: 224 Page(s): 405 - 414
    09/01/1996 Authors: Yang L; Hwang R; Pandit L; Gordon EM; Anderson WF; Parekh D
  • Rat oval cells express antigenic phenotypes identified in primary hepatocellular carcinomas and in developing bile ducts.
    FASEB JOURNAL Volume: 10 Page(s): 1630 - 1630
    04/30/1996 Authors: Chapman L; McBride A; Faris R; Yang L; Hixson DC
  • Isolation, propagation, and characterization of rat liver serosal mesothelial cells.
    Am J Pathol Volume: 145 Page(s): 1432 - 1443
    12/01/1994 Authors: Faris RA; McBride A; Yang L; Affigne S; Walker C; Cha CJ
  • Phenotypic heterogeneity within clonogenic ductal cell populations isolated from normal adult rat liver.
    Proc Soc Exp Biol Med Volume: 204 Page(s): 280 - 288
    12/01/1993 Authors: Yang L; Faris RA; Hixson DC
  • Characterization of a mature bile duct antigen expressed on a subpopulation of biliary ductular cells but absent from oval cells.
    Hepatology Volume: 18 Page(s): 357 - 366
    08/01/1993 Authors: Yang L; Faris RA; Hixson DC
  • Long-term culture and characteristics of normal rat liver bile duct epithelial cells.
    Gastroenterology Volume: 104 Page(s): 840 - 852
    03/01/1993 Authors: Yang L; Faris RA; Hixson DC
Read more publications Fewer publications
Directory
  • Faculty Profiles
Emory University Homepage

Contact & Location

Emory University School of Medicine
100 Woodruff Circle
Atlanta, GA  30322 USA
  • Contact Us
  • Maps & Directions
  • Careers

Information For

  • Alumni
  • Faculty & Staff
  • Patients
  • Residents & Fellows
  • Students
Support the School of Medicine School of Medicine Intranet
facebook facebook twitter twitter linkedin linkedin instagram instagram youtube youtube
© 2025 Emory University
  • Privacy Policy
  • Emergency Information
  • EEO Employer-Disability/Veteran Statements