Kisha Piggott

Current Status: Alumni

Graduate Department: Immunology and Molecular Pathogenesis

Advisor(s): Cornelia Weyand, MD, PhD;

Research

I studied the underlying mechanisms regulating Giant Cell Arteritis (GCA), an inflammatory vasculopathy that targets medium and large arteries. I investigated the role of unique co-stimulatory molecules such as the Notch signaling pathway in disease pathogenesis. Using human artery-mouse chimeras I explored potential therapeutic targets to curb immune responses in the arterial wall, with the ultimate development of two therapeutic approaches which were effective in mitigating the vascular inflammatory response.

Graduation Year: 2011

Residency: Ophthalmology, Washington University