Dr. Yu has published numerous articles in prestigious scientific journals including Nature Genetics, Molecular Cell, Nature Communications and Journal of Clinical Investigation. She serves as associate editor for the following journals: Oncogene, Cell & Bioscience, and Cancer Heterogeneity and Plasticity. She is also the editor-in-chief for Serican Journal of Medicine.
>>Complete list of publications
Selected publications:
- Lu X, Keo V, Cheng I, Xie W, Gritsina G, Wang J, Lu L, Shiau CK, He Y, Jin Q, Jin P, Sanda MG, Corces VG, Altemose N, Gao R, Zhao JC, Yu J. NKX2-1 drives neuroendocrine transdifferentiation of prostate cancer via epigenetic and 3D chromatin remodeling. Nat Genet. 2025 Jul 21. doi: 10.1038/s41588-025-02265-4. Online ahead of print. PMID: 40691407 highlighted in news and in Arima Genomics blog
- Brea L, Yu J. Tumor-intrinsic regulators of the immune-cold microenvironment of prostate cancer . Trends Endocrinol Metab. 2025 Jan 2:S1043-2760(24)00325-4. doi: 10.1016/j.tem.2024.12.003. Online ahead of print. PMID: 39753502 Review.
- Gritsina G, Fong KW, Lu X, Lin Z, Xie W, Agarwal S, Lin D, Schiltz GE, Beltran H, Corey E, Morrissey C, Wang Y, Zhao JC, Hussain M, Yu J. Chemokine receptor CXCR7 activates Aurora Kinase A and promotes neuroendocrine prostate cancer growth. J Clin Invest. 2023 Aug 1;133(15):e166248. doi: 10.1172/JCI166248. PMID: 37347559
- Fong KW, Zhao JC, Lu X, Kim J, Piunti A, Shilatifard A, Yu J. PALI1 promotes tumor growth through competitive recruitment of PRC2 to G9A-target chromatin for dual epigenetic silencing. Mol Cell.2022 Dec 01. PMID: 36476474 highlighted in news
- Lu X, Fong KW, Gritsina G, Wang F, Baca SC, Brea LT, Berchuck JE, Spisak S, Ross J, Morrissey C, Corey E, Chandel NS, Catalona WJ, Yang X, Freedman ML, Zhao JC, Yu J. HOXB13 suppresses de novo lipogenesis through HDAC3-mediated epigenetic reprogramming in prostate cancer. Nat Genet. 2022 April 25. PMID: 35468964 highlighted in news
- Park SH, Fong KW, Kim J, Wang F, Lu X, Lee Y, Brea LT, Wadosky K, Guo C, Abdulkadir SA, Crispino JD, Fang D, Ntziachristos P, Liu X, Li X, Wan Y, Goodrich DW, Zhao JC, Yu J. Posttranslational regulation of FOXA1 by Polycomb and BUB3/USP7 deubiquitin complex in prostate cancer. Science Advances. 2021 April 07. PMID: 33827814 highlighted in news
- Xu B, Song B, Lu X, Kim J, Hu M, Zhao JC, Yu J.Altered chromatin recruitment by FOXA1 mutations promotes androgen independence and prostate cancer progression. Cell Research. 2019 July 19. PMID: 31324884
- Kim J, Lee Y, Lu X, Song B, Fong KW, Cao Q, Licht JD, Zhao JC, Yu J. Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator. Cell Reports. 2018 Dec 04. PMID: 30517868 highlighted in news
- Song B, Park SH, Zhao JC, Fong KW, Li S, Lee Y, Yang YA, Sridhar S, Lu X, Abdulkadir SA, Vessella RL, Morrissey C, Kuzel TM, Catalona WJ, Yang XJ, Yu J. Targeting FOXA1-mediated repression of TGF-β signaling suppresses castration-resistant prostate cancer progression. J Clin Invest. 2018 Dec 04. PMID: 30511964 highlighted in news
- Kim J, Jin H, Zhao JC, Yang YA, Li Y, Yang X, Dong X, Yu J. FOXA1 inhibits prostate cancer neuroendocrine differentiation. Oncogene. 2017 March 20. PMID: 28319070
- Yang YA, Zhao JC, Fong KW, Kim J, Li S, Song C, Song B, Zheng B, He C, Yu J. FOXA1 potentiates lineage-specific enhancer activation through modulating TET1 expression and function. Nucleic Acids Res. 2016 June 01. PMID: 27268279
- Jin HJ, Zhao JC, Wu L, Kim J, Yu J. Cooperativity and equilibrium with FOXA1 define the androgen receptor transcriptional program. Nat Commun. 2014 May 30. PMID: 24875621
- Jin HJ, Zhao JC, Ogden I, Bergan R, Yu J. Androgen-receptor independent function of FoxA1 in prostate cancer metastasis. Cancer Research. 2013 Mar 28. [Epub ahead of print] PMID: 23539448
- Zhao JC, Yu JJ, Runkle C, Wu L, Hu M, Wu D, Liu JS, Wang Q, Qin ZS, Yu J. Cooperation between Polycomb and androgen receptor during oncogenic transformation. Genome Res. 2012 Feb;22(2):322-31. Epub 2011 Dec 16. PMID: 2217985554
- Yu J, Yu JJ, Mani RS, Cao Q, Brenner CJ, Cao X, Wang GX, Wu L ...Qin ZS, Chinnaiyan AM. An Integrated Network of Androgen Receptor, Polycomb, and TMPRSS2-ERG Gene Fusions in Prostate Cancer Progression. Cancer Cell. 2010 May 18;17(5):443-54. Cover Article. PMID: 20478527