(*co-first or co-corresponding author)
2025
- Shu, C., Jin, R., Niu, Q., Cicka, D., Doyle, S., Wahafu, A., Fan, D., Zheng, X., Du, Y., Ivanov, A.A., Doxie, D., Dhodapkar, K., Carlisle, J., Owonikoko, T., Sica, G., Liu, Y., Ramalingam, S., Dhodapkar, M., Zhou, W., Mo, X.*, and Fu, H. (2025). Uncovering the rewired IAP-JAK regulatory axis as an immune-dependent vulnerability of LKB1-mutant lung cancer. Nat Commun. Mar 8;16(1):2324. doi: 10.1038/s41467-025-57297-5.
- Mo, X., Du, Y., and Fu, H. (2025). Evaluation of molecular glue-induced neo-Protein-Protein Interaction with a cell lysate-based TR-FRET assay. ASPET Discovery. Volume 1, 2025, 100003. doi:10.1016/j.aspetd.2025.100003.
- Fan, Y., Jin, R., Monterroza, L., Liu, X., Huang, C., Marra, A., Mo, X., Fu, H., Gilbert-Ross, M., Marcus, AI., Tirouvanziam, R., Liu, Y., Schneider, F., and Zhou, W. (2025). Suppression of LKB1-mutant lung adenocarcinoma by natural killer cells from females. J Natl Cancer Inst. djaf138, https://doi.org/10.1093/jnci/djaf138
2024
- Lindsay, M. E., Scimone, E. R., Lawton, J., Richa, R., Yonker, L. M., Di, Y. P., Buch, K., Ouyang, W., Mo, X., Lin, A. E., & Mou, H. (2024). Gain-of-Function Variants in SMAD4 Compromise Respiratory Epithelial Function. J Allergy Clin Immunol. 2024 Sep 5:S0091-6749(24)00908-4. doi: 10.1016/j.jaci.2024.08.024.
2023
- Cicka, D., Niu, Q., Qui, M., Qian, K., Miller, E., Fan, D., Mo, X., Ivanov, A.A., Sarafianos, S.G., Du, Y., and Fu, H. TMPRSS2 and SARS-CoV-2 SPIKE interaction assay for uHTS. J Mol Cell Biol. 2023 Mar 15; mjad017. doi: 10.1093/jmcb/mjad017.
- Druzak, S.A., Tardelli, M., Mays, S.G., Bejjani, M., Mo, X., Maner-Smith, K., Bowen, T., Cato, M., Tillman, M.C., Sugiyama, A., Xie, Y., Fu, H., Cohen, D.E., and Ortlund, E.A. Ligand dependent interaction between PC-TP and PPARδ mitigates diet-induced hepatic steatosis in male mice. Nat Commun. 2023 May 12;14(1):2748. doi: 10.1038/s41467-023-38010-w.
- Ouyang, W., Li, Q., Niu, Q., Qui, M., Fu, H., Du, Y., and Mo, X. (2023). A multiplexed time-resolved fluorescence resonance energy transfer ultrahigh-throughput screening assay for targeting SMAD4-SMAD3-DNA complex. J Mol Cell Biol. 2023 Nov 15:mjad068. doi: 10.1093/jmcb/mjad068.
202
- Shu C., Zheng X., Wahafu A., Cicka D., Doyle S., Niu Q., Fan D., Qian K., Ivanov AA., Du Y., Mo X.*, Fu H. Acquisition of taxane resistance by p53 inactivation in ovarian cancer cells. Acta Pharmacol Sin. 2022 Jan 14. doi: 10.1038/s41401-021-00847-6.
- Mo, X.*, Q. Niu, A. A. Ivanov, Y. H. Tsang, C. Tang, C. Shu, Q, Li. Q, Kun, A. Wahafu, S. Doyle, D. Cicka, X. Yang, D. Fan, M. A. Reyna, L. A. D. Cooper, C. S. Moreno, W. Zhou, T. Owonikoko, S. Lonial, F. R. Khuri, Y. Du, S. S. Ramalingam, G. B. Mill and H. Fu. Systematic discovery of mutation-directed neo-protein-protein interactions in cancer. Cell. 2022 May 26;185(11):1974-1985.e12. doi: 10.1016/j.cell.2022.04.014.
2021
- Tang C., Niu Q., Cicka D., Du Y., Mo X*., and Fu H. A time-resolved fluorescence resonance energy transfer screening assay for discovery of protein-protein interaction modulators. STAR Protoc. 2021 Sep 8;2(3):100804. doi: 10.1016/j.xpro.2021.100804. eCollection 2021 Sep 17. *co-corresponding author.
2020
- Du Y, Li X, Niu Q, Mo X, Qui M, Ma T, Kuo CJ, Fu H (2020) Development of a miniaturized 3D organoid culture platform for ultra-high throughput screening. J Mol Cell Biol. 2020. mjaa036. doi: 10.1093/jmcb/mjaa036.
- Tang C, Mo X*, Niu Q, Wahafu A, Yang X, Qui M, Ivanov AA, Du Y, Fu H. Hypomorph Mutation-Directed Small-Molecule Protein-Protein Interaction Inducers to Restore Mutant SMAD4-Suppressed TGF-β Signaling. Cell Chem Biol. 2020 Dec 4;S2451-9456(20)30473-6. doi: 10.1016/j.chembiol.2020.11.010. *co-first and co-corresponding author.
2018
- Mo X, Tang C, Niu Q, Ma T, Du Y, Fu H. HTiP: High-Throughput Immunomodulator Phenotypic Screening Platform to Reveal IAP Antagonists as Anti-cancer Immune Enhancers. Cell Chem Biol. 2018. pii: S2451-9456(18)30433-1.