Yu T, Jhita N, Shankles P, Fedanov A, Kramer N, Raikar SS, Sulchek T. Development of a microfluidic cell transfection device into gene-edited CAR T cell manufacturing workflow. Lab Chip. 2023 Nov 7;23(22):4804-4820. doi: 10.1039/d3lc00311f. PMID: 37830228; PMCID: PMC10701762. (Co-senior authors).
Mumme HL, Raikar SS, Bhasin SS, Thomas BE, Lawrence T, Weinzierl EP, Pang Y, DeRyckere D, Gawad C, Wechsler DS, Porter CC, Castellino SM, Graham DK, Bhasin M. Single-cell RNA sequencing distinctly characterizes the wide heterogeneity in pediatric mixed phenotype acute leukemia. Genome Med. 2023 Oct 16;15(1):83. doi: 10.1186/s13073-023-01241-z. PMID: 37845689; PMCID: PMC10577904.
Story JY, Zoine JT, Burnham RE, Hamilton JAG, Spencer HT, Doering CB, Raikar SS. Bortezomib enhances cytotoxicity of ex vivo-expanded gamma delta T cells against acute myeloid leukemia and T-cell acute lymphoblastic leukemia. Cytotherapy. 2021 Jan;23(1):12-24. doi: 10.1016/j.jcyt.2020.09.010. Epub 2020 Nov 6. PMID: 33168453; PMCID: PMC8075174.
Oberley MJ, Raikar SS, Wertheim GB, Malvar J, Sposto R, Rabin KR, Punia JN, Seif AE, Cahen VC, Schore RJ, Luca DC, Guinipero T, Woods WG, O'Gorman MRG, Orgel E. Significance of minimal residual disease in pediatric mixed phenotype acute leukemia: a multicenter cohort study. Leukemia. 2020 Jul;34(7):1741-1750. doi: 10.1038/s41375-020-0741-0. Epub 2020 Feb 14. PMID: 32060402; PMCID: PMC7332384.
Fleischer LC, Spencer HT, Raikar SS. Targeting T cell malignancies using CAR-based immunotherapy: challenges and potential solutions. J Hematol Oncol. 2019 Dec 29;12(1):141. doi: 10.1186/s13045-019-0801-y. PMID: 31884955; PMCID: PMC6936092.
Raikar SS, Fleischer LC, Moot R, Fedanov A, Paik NY, Knight KA, Doering CB, Spencer HT. Development of chimeric antigen receptors targeting T-cell malignancies using two structurally different anti-CD5 antigen binding domains in NK and CRISPR-edited T cell lines. Oncoimmunology. 2017 Dec 26;7(3):e1407898. doi: 10.1080/2162402X.2017.1407898. PMID: 29399409; PMCID: PMC5790337.
Raikar SS, Park SI, Leong T, Jaye DL, Keller FG, Horan JT, Woods WG. Isolated myeloperoxidase expression in pediatric B/myeloid mixed phenotype acute leukemia is linked with better survival. Blood. 2018 Feb 1;131(5):573-577. doi: 10.1182/blood-2017-09-807602. Epub 2017 Dec 9. PMID: 29223952.
Moot R, Raikar SS, Fleischer L, Querrey M, Tylawsky DE, Nakahara H, Doering CB, Spencer HT. Genetic engineering of chimeric antigen receptors using lamprey derived variable lymphocyte receptors. Mol Ther Oncolytics. 2016 Dec 7;3:16026. doi: 10.1038/mto.2016.26. PMID: 27933313; PMCID: PMC5142425. (Co-first authors).