2025
Comparison of viral phenotype and inflammatory biomarker responses in acute HIV-1 subtype A and C infections. McInally S, Claiborne DT, El-Badry E, Xu R, Qin Q, Ende Z, et al. Front Microbiol. 2025;16:1649731. http://dx.doi.org/10.3389/fmicb.2025.1649731
Heterologous two-dose Ebola vaccine regimen in pregnant women in Rwanda: a randomized controlled phase 3 trial. Nyombayire J, Ingabire R, Mazzei A, Sharkey T, Umuhoza C, Mukamuyango J, et al. Nat Med. http://dx.doi.org/10.1038/s41591-025-03932-z
Contraception use and pregnancy in women receiving a 2-dose Ebola vaccine in Rwanda: A retrospective analysis of UMURINZI vaccination campaign data. Ingabire R, Nyombayire J, Mazzei A, Mazarati JB, Noben J, Katwere M, et al. PLoS Med. 2025;22(2):e1004508. http://dx.doi.org/10.1371/journal.pmed.1004508
Heightened expression of type I interferon signaling genes in CD4+ T cells from acutely HIV-1-infected women is associated with lower viral loads. El-Badry E, Chen L, Ghneim K, Li Z, Brooks K, Rhodes J, et al. Front Immunol. 2025;15:1507530. http://dx.doi.org/10.3389/fimmu.2024.1507530
2024
Dynamics of the blood plasma proteome during hyperacute HIV-1 infection. Nazziwa J, Freyhult E, Hong MG, Johansson E, Årman F, Hare J, et al. Nat Commun. 2024;15(1):10593. http://dx.doi.org/10.1038/s41467-024-54848-0
Phenotypic Characterization of Subtype A and Recombinant AC Transmitted/Founder Viruses from a Rwandan HIV-1 Heterosexual Transmission Cohort. Yue L, Xu R, Mclnally S, Qin Q, Rhodes JW, Muok E, et al. Viruses. 2024;16(11):1706. http://dx.doi.org/10.3390/v16111706
Uptake and perceptions of voluntary medical male circumcision among HIV-negative men in serodiscordant relationships in Zambia (2012-2015). Malama K, Allen S, Parker R, Inambao M, Sharkey T, Tichacek A, et al. PLoS One. 2024;19(11):e0309295. http://dx.doi.org/10.1371/journal.pone.0309295
HLA-A*23 Is Associated With Lower Odds of Acute Retroviral Syndrome in Human Immunodeficiency Virus Type 1 Infection: A Multicenter Sub-Saharan African Study. Lindquist L, Kilembe W, Karita E, Price MA, Kamali A, Kaleebu P, et al. Open Forum Infect Dis. 2024;11(4):ofae129. http://dx.doi.org/10.1093/ofid/ofae129
Female Genital Schistosomiasis Lesion Resolution Post-Treatment with Praziquantel in Zambian Adults. Kabengele C, Mwangelwa S, Kilembe W, Vwalika B, Inambao M, Moonga V, et al. Am J Trop Med Hyg. 2024;110(2):250-253. http://dx.doi.org/10.4269/ajtmh.23-0552
2023
Use of "Strengthening Our Vows" Video Intervention to Encourage Negotiated Explicit Sexual Agreements in Zambian Heterosexual HIV Seroconcordant-Negative Couples. Sharkey T, Parker R, Wall KM, Malama K, Pappas-DeLuca K, Tichacek A, et al. Arch Sex Behav. 2023;52(6):2649-2667. http://dx.doi.org/10.1007/s10508-023-02590-x
Monitoring of Adverse Events in Recipients of the 2-Dose Ebola Vaccine Regimen of Ad26.ZEBOV Followed by MVA-BN-Filo in the UMURINZI Ebola Vaccination Campaign. Nyombayire J, Ingabire R, Magod B, Mazzei A, Mazarati JB, Noben J, et al. J Infect Dis. 2023;227(2):268-277. http://dx.doi.org/10.1093/infdis/jiac283
2022
A mixed-methods study of factors influencing postpartum intrauterine device uptake after family planning counseling among women in Kigali, Rwanda. Tounkara MS, Ingabire R, Comeau DL, Karita E, Allen S, Nyombayire J, et al. PLoS One. 2022;17(11):e0276193. http://dx.doi.org/10.1371/journal.pone.0276193
Safety, reactogenicity, and immunogenicity of a 2-dose Ebola vaccine regimen of Ad26.ZEBOV followed by MVA-BN-Filo in healthy adult pregnant women: study protocol for a phase 3 open-label randomized controlled trial. Karita E, Nyombayire J, Ingabire R, Mazzei A, Sharkey T, Mukamuyango J, et al. Trials. 2022;23(1):513. http://dx.doi.org/10.1186/s13063-022-06360-3
Attenuated HIV-1 Nef But Not Vpu Function in a Cohort of Rwandan Long-Term Survivors. Umviligihozo G, Mann JK, Jin SW, Mwimanzi FM, Hsieh AH, Sudderuddin H, et al. Front Virol. 2022;2:917902. http://dx.doi.org/10.3389/fviro.2022.917902
Implementation and evaluation of a large-scale postpartum family planning program in Rwanda: study protocol for a clinic-randomized controlled trial. Wall KM, Ingabire R, Mazzei A, Umuhoza C, Parker R, Tichacek A, et al. Trials. 2022;23(1):337. http://dx.doi.org/10.1186/s13063-022-06261-5
Measles immunity gap among reproductive-age women participating in a simulated HIV vaccine efficacy trial in Zambia. Malama K, Tichacek A, Kelly H, Parker R, Inambao M, Sharkey T, et al. Hum Vaccin Immunother. 2022;18(5):2066426. http://dx.doi.org/10.1080/21645515.2022.2066426
Evolution of Condom Use Among a 5-Year Cohort of Female Sex Workers in Zambia. Malama K, Price MA, Sagaon-Teyssier L, Parker R, Wall KM, Tichacek A, et al. AIDS Behav. 2022;26(2):470-477. http://dx.doi.org/10.1007/s10461-021-03403-9
Antibiotic-resistant Neisseria gonorrhoeae and changes to the 2019 Rwandan National STI Guidelines. Wall KM, Nyombayire J, Parker R, Ingabire R, Bizimana J, Mukamuyango J, et al. Int J STD AIDS. 2022;33(3):315-317. http://dx.doi.org/10.1177/09564624211053242
Cross-sectional assessment of determinants of STIs among men who have sex with men and transgender women in Kigali, Rwanda. Twahirwa Rwema JO, Herbst S, Hamill MM, Liestman B, Nyombayire J, Lyons CE, et al. Sex Transm Infect. 2022;98(3):178-187. http://dx.doi.org/10.1136/sextrans-2020-054753
2021
Cross-sectional assessment of government health center needs to implement long-acting reversible contraception services in rural Rwanda. Mazzei A, Ingabire R, Karita E, Mukamuyango J, Nyombayire J, Parker R, et al. BMC Womens Health. 2021;21(1):411. http://dx.doi.org/10.1186/s12905-021-01555-3
Increased Frequency of Inter-Subtype HIV-1 Recombinants Identified by Near Full-Length Virus Sequencing in Rwandan Acute Transmission Cohorts. Umviligihozo G, Muok E, Nyirimihigo Gisa E, Xu R, Dilernia D, Herard K, et al. Front Microbiol. 2021;12:734929. http://dx.doi.org/10.3389/fmicb.2021.734929
A cluster randomized trial to reduce HIV risk from outside partnerships in Zambian HIV-Negative couples using a novel behavioral intervention, "Strengthening Our Vows": Study protocol and baseline data. Sharkey T, Wall KM, Parker R, Tichacek A, Pappas-DeLuca KA, Kilembe W, et al. Contemp Clin Trials Commun. 2021;24:100850. http://dx.doi.org/10.1016/j.conctc.2021.100850
Developing and validating a risk algorithm to diagnose Neisseria gonorrhoeae and Chlamydia trachomatis in symptomatic Rwandan women. Wall KM, Nyombayire J, Parker R, Ingabire R, Bizimana J, Mukamuyango J, et al. BMC Infect Dis. 2021;21(1):392. http://dx.doi.org/10.1186/s12879-021-06073-z
Etiologies of genital inflammation and ulceration in symptomatic Rwandan men and women responding to radio promotions of free screening and treatment services. Wall KM, Nyombayire J, Parker R, Ingabire R, Bizimana J, Mukamuyango J, et al. PLoS One. 2021;16(4):e0250044. http://dx.doi.org/10.1371/journal.pone.0250044
Elevated levels of inflammatory plasma biomarkers are associated with risk of HIV infection. McInally S, Wall K, Yu T, Tirouvanziam R, Kilembe W, Gilmour J, et al. Retrovirology. 2021;18(1):8. http://dx.doi.org/10.1186/s12977-021-00552-6
HLA-associated preadaptation in HIV Vif is associated with higher set point viral load and faster CD4+ decline in Zambian transmission pairs. Connolly S, Carlson JM, Schaefer M, Bere A, Kilembe W, Allen S, et al. AIDS. 2021;35(8):1157-1165. http://dx.doi.org/10.1097/QAD.0000000000002868
A Stronger Innate Immune Response During Hyperacute Human Immunodeficiency Virus Type 1 (HIV-1) Infection Is Associated With Acute Retroviral Syndrome. Hassan AS, Hare J, Gounder K, Nazziwa J, Karlson S, Olsson L, et al. Clin Infect Dis. 2021;73(5):832-841. http://dx.doi.org/10.1093/cid/ciab139
Genital Abnormalities, Hormonal Contraception, and Human Immunodeficiency Virus Transmission Risk in Rwandan Serodifferent Couples. Wall KM, Karita E, Nyombayire J, Ingabire R, Mukamuyango J, Parker R, et al. J Infect Dis. 2021;224(1):81-91. http://dx.doi.org/10.1093/infdis/jiab071
Antiretroviral Therapy Use and HIV Transmission Among Discordant Couples in Nonresearch Settings in Kigali, Rwanda. Nyombayire J, Ingabire R, Mukamuyango J, Karita E, Mazzei A, Wall KM, et al. Sex Transm Dis. 2021;48(6):424-428. http://dx.doi.org/10.1097/OLQ.0000000000001350
2020
Motivational interviewing to promote long-acting reversible contraception among Rwandan couples wishing to prevent or delay pregnancy. Mukamuyango J, Ingabire R, Parker R, Nyombayire J, Easter SR, Wall KM, et al.Am J Obstet Gynecol. 2020;222(4S):S919 e1-S e12. http://dx.doi.org/10.1016/j.ajog.2019.11.1280
A couple-focused, integrated unplanned pregnancy and HIV prevention program in urban and rural Zambia.Malama K, Kilembe W, Inambao M, Hoagland A, Sharkey T, Parker R, et al. Am J Obstet Gynecol. 2020;222(4S):S915 e1-S e10. http://dx.doi.org/10.1016/j.ajog.2020.01.007
Fertility intentions and long-acting reversible contraceptive use among HIV-negative single mothers in Zambia. Li JL, Kilembe W, Inambao M, Vwalika B, Parker R, Sharkey T, et al. Am J Obstet Gynecol. 2020;222(4S):S917 e1-S e15. http://dx.doi.org/10.1016/j.ajog.2019.12.269
Sociodemographic factors and STIs associated with Chlamydia trachomatis and Neisseria gonorrhoeae infections in Zambian female sex workers and single mothers. Connolly S, Wall KM, Parker R, Kilembe W, Inambao M, Visoiu AM, et al. Int J STD AIDS. 2020;31(4):364-74. http://dx.doi.org/10.1177/0956462419894453
Factors associated with alcohol use before sex among HIV-negative female sex workers in Zambia. Malama K, Sagaon-Teyssier L, Parker R, Tichacek A, Sharkey T, Kilembe W, et al. Int J STD AIDS. 2020;31(2):119-26. http://dx.doi.org/10.1177/0956462419886159
Differential Vpu-Mediated CD4 and Tetherin Downregulation Functions among Major HIV-1 Group M Subtypes.Umviligihozo G, Cobarrubias KD, Chandrarathna S, Jin SW, Reddy N, Byakwaga H, et al. J Virol. 2020;94(14). http://dx.doi.org/10.1128/JVI.00293-20
Identifying the immune interactions underlying HLA class I disease associations. Debebe BJ, Boelen L, Lee JC, Investigators IPC, Thio CL, Astemborski J, et al. Elife. 2020;9. http://dx.doi.org/10.7554/eLife.54558
Better Viral Control despite Higher CD4(+) T Cell Activation during Acute HIV-1 Infection in Zambian Women Is Linked to the Sex Hormone Estradiol. El-Badry E, Macharia G, Claiborne D, Brooks K, Dilernia DA, Goepfert P, et al. J Virol. 2020;94(16). http://dx.doi.org/10.1128/JVI.00758-20
A Population-Specific Optimized GeneXpert Pooling Algorithm for Chlamydia trachomatis and Neisseria gonorrhoeae To Reduce Cost of Molecular Sexually Transmitted Infection Screening in Resource-Limited Settings. Connolly S, Kilembe W, Inambao M, Visoiu AM, Sharkey T, Parker R, et al. J Clin Microbiol. 2020;58(9):39. http://dx.doi.org/10.1128/JCM.00176-20
HIV-1 variants are archived throughout infection and persist in the reservoir. Brooks K, Jones BR, Dilernia DA, Wilkins DJ, Claiborne DT, McInally S, et al. PLoS Pathog. 2020;16(6):e1008378. http://dx.doi.org/10.1371/journal.ppat.1008378
Cost-effectiveness of couples' voluntary HIV counselling and testing in six African countries: a modelling study guided by an HIV prevention cascade framework. Wall KM, Inambao M, Kilembe W, Karita E, Chomba E, Vwalika B, et al. J Int AIDS Soc. 2020;23 Suppl 3:e25522. http://dx.doi.org/10.1002/jia2.25522
Uptake of long acting reversible contraception following integrated couples HIV and fertility goal-based family planning counselling in Catholic and non-Catholic, urban and rural government health centers in Kigali, Rwanda. Mukamuyango J, Ingabire R, Parker R, Nyombayire J, Abaasa A, Asiki G, et al. Reprod Health. 2020;17(1):126. http://dx.doi.org/10.1186/s12978-020-00981-0
Cost-effectiveness of integrated HIV prevention and family planning services for Zambian couples. Wall KM, Kilembe W, Inambao M, Hoagland A, Sharkey T, Malama K, et al. AIDS. 2020;34(11):1633-42. http://dx.doi.org/10.1097/QAD.0000000000002584
Cohort profile: IAVI's HIV epidemiology and early infection cohort studies in Africa to support vaccine discovery. Price MA, Kilembe W, Ruzagira E, Karita E, Inambao M, Sanders EJ, et al. Int J Epidemiol. 2020;2:39. http://dx.doi.org/10.1093/ije/dyaa100
Postpartum long-acting contraception uptake and service delivery outcomes after a multilevel intervention in Kigali, Rwanda. Espey J, Ingabire R, Nyombayire J, Hoagland A, Da Costa V, Mazzei A, et al. BMJ Sex Reprod Health. 2020. http://dx.doi.org/10.1136/bmjsrh-2020-200741
HIV infection and engagement in HIV care cascade among men who have sex with men and transgender women in Kigali, Rwanda: a cross-sectional study. Twahirwa Rwema JO, Lyons CE, Herbst S, Liestman B, Nyombayire J, Ketende S, et al. J Int AIDS Soc. 2020;23 Suppl 6(Suppl 6):e25604. http://dx.doi.org/10.1002/jia2.25604
Loss to follow-up among female sex workers in Zambia: findings from a five-year HIV-incidence cohort. Malama K, Sagaon-Teyssier L, Gosset A, Parker R, Wall KM, Tichacek A, et al. Afr J AIDS Res. 2020;19(4):296-303. http://dx.doi.org/10.2989/16085906.2020.1836005
2019
Reduced frequency of HIV superinfection in a high-risk cohort in Zambia. Woodson E, Basu D, Olszewski H, Gilmour J, Brill I, Kilembe W, et al. Virology. 2019;535:11-9. DOI
HIV testing and counselling couples together for affordable HIV prevention in Africa. Wall KM, Inambao M, Kilembe W, Karita E, Vwalika B, Mulenga J, et al. Int J Epidemiol. 2019;48(1):217-27. DOI
Control of the HIV-1 Load Varies by Viral Subtype in a Large Cohort of African Adults With Incident HIV-1 Infection. Price MA, Rida W, Kilembe W, Karita E, Inambao M, Ruzagira E, et al. J Infect Dis. 2019;220(3):432-41. DOI
Community health worker promotions increase uptake of long-acting reversible contraception in Rwanda. Mazzei A, Ingabire R, Mukamuyango J, Nyombayire J, Sinabamenye R, Bayingana R, et al. Reprod Health. 2019;16(1):75. DOI
Client-Initiated Violence Against Zambian Female Sex Workers: Prevalence and Associations With Behavior, Environment, and Sexual History. Malama K, Sagaon-Teyssier L, Parker R, Tichacek A, Sharkey T, Kilembe W, et al. J Interpers Violence. 2019:886260519860083. DOI
Single Mothers and Female Sex Workers in Zambia Have Similar Risk Profiles. Kilembe W, Inambao M, Sharkey T, Wall KM, Parker R, Himukumbwa C, et al. AIDS Res Hum Retroviruses. 2019;35(9):814-25. DOI
Female sex workers in Kigali, Rwanda: a key population at risk of HIV, sexually transmitted infections, and unplanned pregnancy. Ingabire R, Parker R, Nyombayire J, Ko JE, Mukamuyango J, Bizimana J, et al. International journal of STD & AIDS. 2019;30(6):557-68. DOI
Development and Uptake of Long-Acting Reversible Contraception Services in Rwanda, 2009-2016. Ingabire R, Mukamuyango J, Nyombayire J, Easter SR, Parker R, Mazzei A, et al. Journal of women's health (2002). 2019;28(12):1640-9. DOI
Hormonal Contraception and Vaginal Infections Among Couples Who Are Human Immunodeficiency Virus Serodiscordant in Lusaka, Zambia. Haddad LB, Wall KM, Tote K, Kilembe W, Vwailika B, Sharkey T, et al. Obstet Gynecol. 2019;134(3):573-80. DOI
An Exploratory Analysis of Factors Associated With Interest in Postpartum Intrauterine Device Uptake Among Pregnant Women and Couples in Kigali, Rwanda. Da Costa V, Ingabire R, Sinabamenye R, Karita E, Umutoni V, Hoagland A, et al. Clin Med Insights Reprod Health. 2019;13:1179558119886843. DOI
Protective HLA alleles are associated with reduced LPS levels in acute HIV infection with implications for immune activation and pathogenesis. Claiborne DT, Scully EP, Palmer CD, Prince JL, Macharia GN, Kopycinski J, et al. PLoS pathogens. 2019;15(8):e1007981. DOI
Predominance of the heterozygous CCR5 delta-24 deletion in African individuals resistant to HIV infection might be related to a defect in CCR5 addressing at the cell surface. Arendt V, Amand M, Iserentant G, Lemaire M, Masquelier C, Ndayisaba GF, et al. J Int AIDS Soc. 2019;22(9):e25384. DOI