Gut-derived bacterial toxins impair memory CD4 T-cell mitochondrialfunction in HIV-1infection Fighting the SARS-CoV-2 pandemic requires a global approach to understanding the heterogeneity of vaccine responses Translocated microbiome composition determines immunological outcome in treated HIV infection The transcription factor CREB1 is a mechanistic driver of immunogenicity and reduced HIV-1 acquisition following ALVAC vaccination IFN-α blockade during ART-treated SIV infection lowers tissue vDNA, rescues immune function, and improves overall health Immune mechanisms in cancer patients that lead to poor outcomes of SARS-CoV-2 infection "Go", "No Go," or "Where to Go"; does microbiota dictate T cell exhaustion, programming, and HIV persistence? Translating known drivers of COVID-19 disease severity to design better SARS-CoV-2 vaccines