Publications by Rafi Ahmed

  • Lau, L.L., B.D. Jamieson, T. Somasundaram, and R.Ahmed. 1994. Cytotoxic T cell memory without antigen. Nature 369:648-652.  (>520 citations)
  • Matloubian, M., R.J. Concepcion, and R. Ahmed. 1994. CD4+ T cells are required to sustain CD8+ cytotoxic T cell responses during chronic viral infection.J.Virol. 68:8056-8063. (>710 citations)
  • Ahmed, R. and D. Gray. 1996. Immunological memory and protective immunity: understanding their relation. Science 272:54-60.  (>1090 citations)
  • Murali-Krishna, K., J.D. Altman, M. Suresh, D. Sourdive, A. Zajac, J.Miller, J. Slansky, and R. Ahmed.  1998.  Counting antigen specific CD8 T cells:  A re-evaluation of bystander activation during viral infection.  Immunity 8: 177-187. (>1430 citations)
  • Zajac, A.J., J.N. Blattman, K. Murali-Krishna, D.J.D. Sourdive, M. Suresh, J.D. Altman, and R. Ahmed. 1998.  Viral immune evasion due to persistence of activated T-cells without effector function.  J. Exp. Med. 188: 2205-2213. (>910 citations)
  • Murali-Krishna, K., L.L. Lau, S. Sambhara, F.Lemonnier, J.D. Altman, and R. Ahmed. 1999. Persistence of memory CD8 T cells in MHC class I deficient mice. Science 286: 1377-1381.  (>530 citations)
  • Kaech, S.M., S. Hemby, E. Kersh, and R. Ahmed. 2002. Molecular and functional profiling of memory CD8 T cell differentiation. Cell 111: 837-851.  (>530 citations)
  • Wherry, E.J., V. Teichgräber, T. Becker, S. Kaech, R. Antia, and R. Ahmed. 2003.Memory T cell subsets: Lineage relationship and protective immunity of memory CD8 T cell subsets. Nature Immunol. 4: 225-234.  (>960 citations)
  • Kaech, S.M., J.T. Tan, E.J. Wherry, B.T. Konieczny, C.D. Surh, and R. Ahmed. 2003.  Selective IL-7R expression identifies effector CD8 T cells that give rise to long-lived memory cells.  NatureImmunol.  4: 1191-1198.  (>870 citations)
  • Barber, D.L., E.J. Wherry, D. Masopust, B. Zhu, J.P. Allison, A.H. Sharpe, G.J. Freeman, and R. Ahmed. 2006.  Restoring function in exhausted CD8 T cells during chronic viral infection.  Nature 439: 682-689.  (>1200 citations)
  • Wherry, E.J., S.J. Ha, S.M. Kaech, W.N. Haining, S. Sarkar, V. Kalia, S. Subramaniam, J.N. Blattman, D.L. Barber, and R. Ahmed.  2007.  Molecular signature of CD8+ T cell exhaustion during chronic viral infection.  Immunity 27: 670-684. (>530 citations)
  • Ha, S.J., S.N. Mueller, E.J. Wherry, D.L. Barber, R.D. Aubert, A.H. Sharpe, G.J. Freeman, and R. Ahmed. 2008.  Enhancing therapeutic vaccination by blocking PD-1 mediated inhibitory signals during chronic infection.  J. Exp. Med. 205: 543-555. (>100 citations)
  • Araki, K., A.P. Turner, V.O. Shaffer, S. Gangappa, S.A. Keller, M.F. Bachmann, C.P. Larsen, and R. Ahmed.  2009.  mTOR regulates memory CD8 T-cell differentiation.  Nature 460: 108-113.  (>330 citations)
  • West, E.E., HT. Jin, A.R. Mohammed, P. Penaloza-MacMaster, SJ. Ha, W.G. Tan, B. Youngblood, G.J. Freeman, K.A. Smith, and R. Ahmed.  2013. PD-L1 blockade synergizes with IL-2 therapy in reinvigorating exhausted T cells.  J. Clin. Invest. 123:2604-15.