Our current laboratory effort has four primary research projects:
- defining protein associations and signaling networks that underlie specific tumor cell characteristics including glioma cell migration, cytoskeletal rearrangements, extracellular matrix interactions, metabolism, and glioma stem cells;
- evaluating ways to more specifically target glioma cells with fluorescent probes that may aid in surgical resections;
- comparing genomic and proteomic signatures between Western and African society meningiomas to better understand the differences in these patient populations; and
- utilizing local institutional and large national clinical databases to better characterize various brain tumor patients and responses to treatments.