Caspary Lab

Through chemical mutagenesis of the mouse, the Caspary lab has identified over 20 recessive mutations that result in specific defects during development. This approach is especially fruitful as it permits us to focus on novel genes. We combine biochemical, molecular, cellular, and genetic approaches to figure out the mechanisms underlying the function of these genes.

Fridovich-Keil Lab

Dr. Judith Fridovich-Keil's lab is conducting research to better understand epimerase-deficient galactosemia. The research study utilizes both biochemical and genetic analyses to investigate why some patients with galactosemia are more severely affected than others, what different types of mutations cause galactosemia, and how specific mutations may influence patient outcomes.

Jin Lab

The long-term goal of the Jin Research Group is to combine various disciplines (genetics, biochemistry, chemistry, human genetics/genomics, and bioinformatics) to understand the roles of epigenetics and noncoding RNAs in human diseases, particularly neurodevelopmental and neurodegenerative disorders.

Leslie Lab

The Leslie Lab is focused on understanding the etiology of craniofacial phenotypes by combining deep phenotyping and genomics. Our primary phenotype of interest is orofacial clefts, the most common craniofacial anomaly in humans. We use deep phenotyping in individuals with orofacial clefts and their family members, genetic association methods, and next-generation sequencing to identify novel genetic risk factors and to understand fundamental questions of phenotypic heterogeneity, penetrance, and variable expressivity.

Singh Research Lab

The Singh Research Group is associated with the Emory University School of Medicine, Department of Human Genetics and is located in Atlanta, Georgia. Our research focuses on advancing treatment strategies for Inherited Metabolic Disorders.

Sloan Lab

The Sloan Lab is pursuing two big picture topics. First, how do human glia develop and what makes them unique? Secondly, given that glia play critical roles in helping neural circuit development, does abnormal glial development contribute to neurodevelopmental disorders like autism and schizophrenia?

Weinshenker Lab

The Weinshenker lab's approach is to use a combination of genetics, behavior, pharmacology, neurochemistry, optogenetics, and chemogenetics in rodents to better understand the neurobiology underlying normal brain function as well as neurological and neuropsychiatric disease. These include Alzheimer’s disease, Parkinson’s disease, drug addiction, sleep disorders, depression, and anxiety.

The Yao Lab

The Yao Lab is studying the pivotal roles epigenetic marks play in mammalian neurodevelopment and neuronal functions, as well as how dysregulation of these marks contributes to neurological, neurodegenerative and neuropsychiatric disorders.

Zwick Lab

The Zwick Lab uses genomics and bioinformatics technologies to identify rare genetic variation that contributes to pediatric disorders, early-onset disorders, or rare phenotypes with unusual clinical presentation or familial aggregation. Areas of interest include autism, congenital heart defects, early-onset inflammatory bowel disease, and schizophrenia. Precision medicine (All of Us Research Program) and cloud computing are also pursued.