Dunham Lab | Emory School of Medicine

The Dunham laboratory aims to define how regulation of protein synthesis alters critical aspects of cellular function in ways which are essential for life. We view the ribosome as a cellular hub and sensor of environmental conditions that regulates stress responses and gene expression.

We are interested in a range of translational control mechanisms including how the genetic code in mRNA is preserved, how engineered tRNAs can be manipulated for non-natural amino acid incorporation, to more pressing clinical challenges such antibiotic resistance and persistence. Broadly, our studies address how signals are transmitted to and from the ribosome in its role as a sensor of cellular homeostasis.

Latest News

Congrats to grad student Pooja Srinivas for her 2022 RNA Society Conference Post Award!

Congrats to grad student Ian Pavelich for defending his PhD thesis!

Congrats to grad student Ha An Nguyen for defending her PhD thesis!

Congrats to grad student Ha An Nguyen for being named the 2021 APS SER-CAT Young Investigator!

Congrats to Christine for being named a Kavli fellow from the National Academy of Sciences!

Congrats to grad student Pooja Srinivas for winning a poster prize from the Protein Society!

Congrats to grad student Julia Tanquary for receiving an NSF GRFP fellowship!

Research News

Congrats to Eric and Pooja for their paper published in Nature Communications on paper on novel antibiotics targeting ribosome rescue!

Congrats to grad student Pooja Srinivas for her paper published in Nucleic Acids Research on how oxidation changes the PheRS structure!

Congrats to grad student Ha An Nguyen on her paper published in PNAS!

Congrats to Eric on his paper published in eLife! Read more at the Emory Lab Land Blog

Congrats to Ian and Eric for their paper published in Nucleic Acids Research!

We are grateful for receiving the 2018 Cozzarelli Prize from the National Academy of Sciences for the Best Biological Sciences Paper published in 2018!

Current Lab Funding: