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Steven Yarmoska

Current Status: GRAD

Graduate Department: Biomedical Engineering

Previous Education: BSE, Biomedical Engineering, Duke University;  

Advisor(s): Stanislav Emelianov, PhD;

Hometown: Hillsborough, NJ


Playing/listening to jazz, watching college sports (Blue Devils and Longhorns), playing volleyball, cooking, gardening


Perfluorocarbon Nanodroplets for the Detection and Treatment of Nodal Metastases

Perfluorocarbon nanodroplets (PFCnDs) are an emerging ultrasound contrast agent fundamentally based on clinically-utilized gas microbubbles. These nanodroplets are roughly five times smaller than microbubbles and can therefore reach extravascular targets, such as tumors and lymphatics. I am working to engineer PFCnDs that can be used as theranostic agents to detect sentinel lymph nodes, assess them for metastases, and deliver chemotherapeutic drugs to treat these metastases non-surgically under ultrasound image guidance. The goal is to pre-clinically validate this theranostic platform in a murine model of metastatic breast cancer.

Shear Wave Elasticity Imaging to Assess the Malignant Potential of Thyroid Nodules

Shear wave elasticity imaging (SWEI) is a clinically-implemented, ultrasound-based imaging technique that generates images with contrast based on the stiffness of biological tissue. Our lab has recently developed a novel multi-angle SWEI technique to create these stiffness images with increased accuracy and over a large imaging region of interest. I am working to execute clinical proof-of-concept studies using this SWEI technique in patients with thyroid nodules to evaluate the ability of this technique in predicting the malignant potential of these nodules. The goal is to validate this SWEI technique to eventually guide biopsy decisions, thus avoiding the unnecessary biopsy of benign lesions.

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